EA201200377A8 - Способ пероральной контрацепции у женщин, способ управления нежелательными кровотечениями и предназначенная для применения в этих способах фармацевтическая упаковка - Google Patents

Способ пероральной контрацепции у женщин, способ управления нежелательными кровотечениями и предназначенная для применения в этих способах фармацевтическая упаковка

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EA201200377A8
EA201200377A8 EA201200377A EA201200377A EA201200377A8 EA 201200377 A8 EA201200377 A8 EA 201200377A8 EA 201200377 A EA201200377 A EA 201200377A EA 201200377 A EA201200377 A EA 201200377A EA 201200377 A8 EA201200377 A8 EA 201200377A8
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days
break
specified
oral
period
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EA201200377A
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EA031227B1 (ru
EA201200377A1 (ru
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Андреас Заксе
Патриция Дж. Сулак
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Байер Фарма Акциенгезельшафт
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Application filed by Байер Фарма Акциенгезельшафт filed Critical Байер Фарма Акциенгезельшафт
Publication of EA201200377A1 publication Critical patent/EA201200377A1/ru
Publication of EA201200377A8 publication Critical patent/EA201200377A8/ru
Publication of EA031227B1 publication Critical patent/EA031227B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Изобретение касается способов женской пероральной контрацепции и управления нежелательными кровотечениями в течение пероральной контрацепции у женщин, которые включают монофазный длительный циклический режим приема гормонального контрацептива, применяемого для контроля проблем, связанных с кровотечением, а также соответствующих фармацевтических упаковок. Причем пероральный контрацептив включает 20 мкг этинилэстрадиола и 3 мг дроспиренона, и его принимают ежедневно в течение первого периода, который составляет 24 дня, а затем прием указанного перорального контрацептива ежедневно в течение второго периода, который составляет максимум 96 дней, в течение которого (а) указанная женщина инициирует перерыв, который составляет 3-6 дней, при котором пероральный контрацептив не принимается, или (б) если такой перерыв не инициируется в течение указанного максимума 96 дней, указанная женщина инициирует перерыв, который составляет 3-6 дней в конце периода, который составляет 96 дней (1). После указанного перерыва прием указанного перорального контрацептива осуществляют со схемой приема/перерыва в соответствии с вышеприведенным (1). Причем в этих способах указанный второй период имеет длину по меньшей мере один день.
EA201200377A 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах EA031227B1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56644304P 2004-04-30 2004-04-30
US57502404P 2004-05-28 2004-05-28
US57719904P 2004-06-07 2004-06-07
US63838004P 2004-12-27 2004-12-27
US66006805P 2005-03-10 2005-03-10

Publications (3)

Publication Number Publication Date
EA201200377A1 EA201200377A1 (ru) 2012-08-30
EA201200377A8 true EA201200377A8 (ru) 2018-01-31
EA031227B1 EA031227B1 (ru) 2018-12-28

Family

ID=35056905

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201200377A EA031227B1 (ru) 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах
EA200601908A EA016625B1 (ru) 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов

Family Applications After (1)

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EA200601908A EA016625B1 (ru) 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов

Country Status (29)

Country Link
US (3) US8163721B2 (ru)
EP (1) EP1747001B1 (ru)
JP (4) JP2007535519A (ru)
KR (4) KR20070004919A (ru)
CN (1) CN103127156A (ru)
AR (1) AR048722A1 (ru)
AU (1) AU2005237255B2 (ru)
BR (1) BRPI0510493A (ru)
CA (1) CA2562296A1 (ru)
CR (1) CR8709A (ru)
DK (1) DK1747001T3 (ru)
EA (2) EA031227B1 (ru)
EC (1) ECSP066999A (ru)
ES (1) ES2704999T3 (ru)
HU (1) HUE041475T2 (ru)
IL (1) IL178458A (ru)
LT (1) LT1747001T (ru)
MX (1) MXPA06012567A (ru)
MY (1) MY151322A (ru)
NO (1) NO341685B1 (ru)
NZ (1) NZ586107A (ru)
PA (1) PA8631801A1 (ru)
PE (1) PE20060467A1 (ru)
SG (2) SG152288A1 (ru)
SI (1) SI1747001T1 (ru)
SV (1) SV2006002100A (ru)
TW (1) TWI374735B (ru)
UY (1) UY28875A1 (ru)
WO (1) WO2005105103A2 (ru)

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IL178458A0 (en) 2008-04-13
JP2015187157A (ja) 2015-10-29
KR20070004919A (ko) 2007-01-09
AU2005237255B2 (en) 2011-07-07
NZ586107A (en) 2012-05-25
ES2704999T3 (es) 2019-03-21
IL178458A (en) 2016-08-31
CA2562296A1 (en) 2005-11-10
TWI374735B (en) 2012-10-21
JP2007535519A (ja) 2007-12-06
US20050250747A1 (en) 2005-11-10
KR20150058555A (ko) 2015-05-28
MXPA06012567A (es) 2006-12-15
US20150174142A1 (en) 2015-06-25
SG152288A1 (en) 2009-05-29
WO2005105103A3 (en) 2006-09-08
ECSP066999A (es) 2006-12-29
EA200601908A1 (ru) 2007-04-27
SI1747001T1 (sl) 2019-02-28
US8163721B2 (en) 2012-04-24
EP1747001B1 (en) 2018-10-10
EP1747001A2 (en) 2007-01-31
EA031227B1 (ru) 2018-12-28
JP2013018787A (ja) 2013-01-31
BRPI0510493A (pt) 2007-11-13
KR101812160B1 (ko) 2017-12-27
KR20130022425A (ko) 2013-03-06
HUE041475T2 (hu) 2019-05-28
JP6153967B2 (ja) 2017-06-28
CN103127156A (zh) 2013-06-05
JP6134491B2 (ja) 2017-05-24
EA201200377A1 (ru) 2012-08-30
AR048722A1 (es) 2006-05-17
KR20160150113A (ko) 2016-12-28
EA016625B1 (ru) 2012-06-29
TW200603781A (en) 2006-02-01
US20120202779A1 (en) 2012-08-09
CR8709A (es) 2007-08-28
AU2005237255A1 (en) 2005-11-10
PA8631801A1 (es) 2006-11-09
DK1747001T3 (en) 2019-02-04
SV2006002100A (es) 2006-02-15
PE20060467A1 (es) 2006-06-11
SG10201701904TA (en) 2017-05-30
NO20065499L (no) 2006-11-29
NO341685B1 (no) 2017-12-18
WO2005105103A2 (en) 2005-11-10
JP2017048253A (ja) 2017-03-09
LT1747001T (lt) 2019-01-25
MY151322A (en) 2014-05-15
UY28875A1 (es) 2005-11-30

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