JP2007530551A5 - - Google Patents

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Publication number
JP2007530551A5
JP2007530551A5 JP2007505055A JP2007505055A JP2007530551A5 JP 2007530551 A5 JP2007530551 A5 JP 2007530551A5 JP 2007505055 A JP2007505055 A JP 2007505055A JP 2007505055 A JP2007505055 A JP 2007505055A JP 2007530551 A5 JP2007530551 A5 JP 2007530551A5
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JP
Japan
Prior art keywords
seq
monoclonal antibody
nos
myostatin
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007505055A
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English (en)
Japanese (ja)
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JP2007530551A (ja
JP4695133B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/009307 external-priority patent/WO2005094446A2/en
Publication of JP2007530551A publication Critical patent/JP2007530551A/ja
Publication of JP2007530551A5 publication Critical patent/JP2007530551A5/ja
Application granted granted Critical
Publication of JP4695133B2 publication Critical patent/JP4695133B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007505055A 2004-03-23 2005-03-17 抗ミオスタチン抗体 Expired - Fee Related JP4695133B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55545604P 2004-03-23 2004-03-23
US60/555,456 2004-03-23
US55962104P 2004-04-05 2004-04-05
US60/559,621 2004-04-05
PCT/US2005/009307 WO2005094446A2 (en) 2004-03-23 2005-03-17 Anti-myostatin antibodies

Publications (3)

Publication Number Publication Date
JP2007530551A JP2007530551A (ja) 2007-11-01
JP2007530551A5 true JP2007530551A5 (https=) 2009-02-12
JP4695133B2 JP4695133B2 (ja) 2011-06-08

Family

ID=35064367

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007505055A Expired - Fee Related JP4695133B2 (ja) 2004-03-23 2005-03-17 抗ミオスタチン抗体

Country Status (14)

Country Link
US (1) US20070178095A1 (https=)
EP (1) EP1733041B1 (https=)
JP (1) JP4695133B2 (https=)
KR (1) KR20060133049A (https=)
AT (1) ATE557042T1 (https=)
AU (1) AU2005227896B2 (https=)
BR (1) BRPI0508716A (https=)
CA (1) CA2558805C (https=)
EA (1) EA014112B1 (https=)
ES (1) ES2384176T3 (https=)
IL (1) IL177956A (https=)
MX (1) MXPA06010929A (https=)
NO (1) NO20064788L (https=)
WO (1) WO2005094446A2 (https=)

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ES2892925T3 (es) 2006-03-31 2022-02-07 Chugai Pharmaceutical Co Ltd Métodos para controlar la farmacocinética en sangre de anticuerpos
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CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
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JO3340B1 (ar) 2010-05-26 2019-03-13 Regeneron Pharma مضادات حيوية لـعامل تمايز النمو 8 البشري
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ES3047691T3 (en) 2012-08-01 2025-12-04 Ikaika Therapeutics Inc Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (ltbp4)
TW202237660A (zh) 2012-08-24 2022-10-01 日商中外製藥股份有限公司 FcγRIIb特異性Fc區域變異體
EP3597747B1 (en) 2012-08-24 2023-03-15 Chugai Seiyaku Kabushiki Kaisha Mouse fcgammarii-specific fc antibody
TWI633117B (zh) 2012-09-13 2018-08-21 必治妥美雅史谷比公司 結合至肌肉生長抑制素(myostatin)以纖維連接蛋白爲主之支架結構域蛋白質
AU2014250434B2 (en) 2013-04-02 2019-08-08 Chugai Seiyaku Kabushiki Kaisha Fc region variant
EP2983694B1 (en) 2013-04-08 2022-06-22 President and Fellows of Harvard College Compositions for rejuvenating skeletal muscle stem cells
HRP20251426T1 (hr) 2013-05-06 2026-01-02 Scholar Rock, Inc. Sastavi i postupci za modulaciju faktora rasta
EP3881859B1 (en) * 2013-06-11 2024-03-06 President and Fellows of Harvard College Compositions for increasing neurogenesis and angiogenesis
TW201920262A (zh) 2013-07-30 2019-06-01 美商再生元醫藥公司 抗活化素a之抗體及其用途
EP3119424A4 (en) 2014-03-19 2017-09-13 MacKay Medical Foundation the Presbyterian Church in Taiwan MacKay Memorial Hospital Immunogenic glycopeptides, composition comprising the glycopeptides and use thereof
HK1243940A1 (zh) 2014-11-06 2018-07-27 Scholar Rock, Inc. 抗原肌肉生长抑制素/潜在肌肉生长抑制素的抗体及其用途
KR101860280B1 (ko) 2014-12-19 2018-05-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
CN114773470A (zh) 2015-02-05 2022-07-22 中外制药株式会社 包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il-8-结合抗体及其应用
WO2016168613A1 (en) 2015-04-15 2016-10-20 Regeneron Pharmaceuticals, Inc. Methods of increasing strength and functionality with gdf8 inhibitors
LT3350220T (lt) 2015-09-15 2021-09-27 Scholar Rock, Inc. Anti pro/latentinio miostatino antikūnai ir jų panaudojimas
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
CA3010799A1 (en) 2016-01-06 2017-07-13 President And Fellows Of Harvard College Treatment with gdf11 prevents weight gain, improves glucose tolerance and reduces hepatosteatosis
CN115814077A (zh) 2016-01-08 2023-03-21 供石公司 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法
KR102306744B1 (ko) 2016-06-17 2021-09-28 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체 및 사용 방법
TWI693940B (zh) 2016-08-05 2020-05-21 日商中外製藥股份有限公司 Il-8相關疾病之治療用或預防用組成物
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CN111787981B (zh) 2018-03-01 2025-12-30 瑞泽恩制药公司 增加肌肉量和减少脂肪量的方法
DK3773713T3 (da) 2018-04-06 2025-08-18 Regeneron Pharma Leptinreceptoragonistantistof til anvendelse i forøgelse af knoglemasse hos et individ, der lider af metabolisk dysfunktion eller hypoleptinæmI
KR20210104744A (ko) 2018-12-18 2021-08-25 리제너론 파마슈티칼스 인코포레이티드 렙틴 수용체, gdf8 및 액티빈 a에 대한 길항제를 사용하여 체중 및 제지방 근육량을 향상시키기 위한 조성물 및 방법
CA3124415A1 (en) 2018-12-21 2020-06-25 Northwestern University Use of annexins in preventing and treating muscle membrane injury
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CN120187750A (zh) 2022-09-21 2025-06-20 瑞泽恩制药公司 治疗肥胖、糖尿病和肝功能障碍的方法
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