JP2007523151A5 - - Google Patents

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Publication number
JP2007523151A5
JP2007523151A5 JP2006553697A JP2006553697A JP2007523151A5 JP 2007523151 A5 JP2007523151 A5 JP 2007523151A5 JP 2006553697 A JP2006553697 A JP 2006553697A JP 2006553697 A JP2006553697 A JP 2006553697A JP 2007523151 A5 JP2007523151 A5 JP 2007523151A5
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JP
Japan
Prior art keywords
pyrido
ylamino
pyridin
pyrimidin
piperazin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006553697A
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English (en)
Japanese (ja)
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JP2007523151A (ja
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Publication date
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Priority claimed from PCT/IB2005/000300 external-priority patent/WO2005082903A1/en
Publication of JP2007523151A publication Critical patent/JP2007523151A/ja
Publication of JP2007523151A5 publication Critical patent/JP2007523151A5/ja
Withdrawn legal-status Critical Current

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JP2006553697A 2004-02-18 2005-02-07 ２−（ピリジン−３−イルアミノ）−ピリド［２，３−ｄ］ピリミジン−７−オン Withdrawn JP2007523151A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54536104P 2004-02-18 2004-02-18
PCT/IB2005/000300 WO2005082903A1 (en) 2004-02-18 2005-02-07 2-(pyridin-3-ylamino)-pyrido[2,3-d]pyrimidin-7-ones

Publications (2)

Publication Number Publication Date
JP2007523151A JP2007523151A (ja) 2007-08-16
JP2007523151A5 true JP2007523151A5 (https=) 2008-02-28

Family

ID=34910727

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006553697A Withdrawn JP2007523151A (ja) 2004-02-18 2005-02-07 ２−（ピリジン−３−イルアミノ）−ピリド［２，３−ｄ］ピリミジン−７−オン

Country Status (6)

Country Link
US (1) US20050182078A1 (https=)
EP (1) EP1718645A1 (https=)
JP (1) JP2007523151A (https=)
BR (1) BRPI0507852A (https=)
CA (1) CA2555724A1 (https=)
WO (1) WO2005082903A1 (https=)

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US8389533B2 (en) * 2008-04-07 2013-03-05 Amgen Inc. Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors
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ES2525866T3 (es) 2010-08-05 2014-12-30 Temple University - Of The Commonwealth System Of Higher Education 8-alquil-7-oxo-7,8-dihidropirido [2,3-d]pirimidina-6-carbonitrilos sustituidos en 2 y usos de los mismos
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
EP2937349B1 (en) 2011-03-23 2016-12-28 Amgen Inc. Fused tricyclic dual inhibitors of cdk 4/6 and flt3
RS58514B1 (sr) 2012-06-13 2019-04-30 Incyte Holdings Corp Supstituisana triciklična jedinjenja kao inhibitori fgfr
US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
PH12015502383B1 (en) 2013-04-19 2023-02-03 Incyte Holdings Corp Bicyclic heterocycles as fgfr inhibitors
CN105294682B (zh) 2014-07-26 2017-07-07 广东东阳光药业有限公司 Cdk类小分子抑制剂的化合物及其用途
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
TWI712601B (zh) 2015-02-20 2020-12-11 美商英塞特公司 作為fgfr抑制劑之雙環雜環
US9580423B2 (en) 2015-02-20 2017-02-28 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
PT3497103T (pt) 2016-08-15 2021-06-17 Pfizer Inibidores de piridopirimidinona cdk2/4/6
CN108191857B (zh) * 2017-01-24 2020-10-23 晟科药业（江苏）有限公司 6-取代的吡啶并[2,3-d]嘧啶类化合物作为蛋白激酶抑制剂
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
CN111032655B (zh) * 2017-08-31 2022-09-02 达纳-法伯癌症研究所股份有限公司 Egfr和/或her2抑制剂和使用方法
AU2019262579B2 (en) 2018-05-04 2024-09-12 Incyte Corporation Salts of an FGFR inhibitor
HRP20241288T1 (hr) 2018-05-04 2024-12-06 Incyte Corporation Čvrsti oblici fgfr inhibitora i postupci za njihovu proizvodnju
US12312346B2 (en) * 2018-06-27 2025-05-27 Tufts Medical Center, Inc. Pyridopyrimidine compounds and methods of their use
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CA3150681A1 (en) 2019-08-14 2021-02-18 Incyte Corporation Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
WO2021067374A1 (en) 2019-10-01 2021-04-08 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
US11851426B2 (en) * 2019-10-11 2023-12-26 Incyte Corporation Bicyclic amines as CDK2 inhibitors
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US11981671B2 (en) 2021-06-21 2024-05-14 Incyte Corporation Bicyclic pyrazolyl amines as CDK2 inhibitors
US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors
CN117430597A (zh) * 2022-07-14 2024-01-23 浙江同源康医药股份有限公司 用作cdk4激酶抑制剂的化合物及其应用
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