JP2014503544A5 - - Google Patents
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- Publication number
- JP2014503544A5 JP2014503544A5 JP2013545540A JP2013545540A JP2014503544A5 JP 2014503544 A5 JP2014503544 A5 JP 2014503544A5 JP 2013545540 A JP2013545540 A JP 2013545540A JP 2013545540 A JP2013545540 A JP 2013545540A JP 2014503544 A5 JP2014503544 A5 JP 2014503544A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- alkyl
- pyrazol
- fluorophenyl
- pyrrolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCC(CO1)=C(*C)C1=O Chemical compound CCC(CO1)=C(*C)C1=O 0.000 description 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061425213P | 2010-12-20 | 2010-12-20 | |
| US61/425,213 | 2010-12-20 | ||
| PCT/IB2011/055489 WO2012085721A1 (en) | 2010-12-20 | 2011-12-06 | Novel fused pyridine compounds as casein kinase inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015005142A Division JP5876596B2 (ja) | 2010-12-20 | 2015-01-14 | カゼインキナーゼ阻害剤としての新規縮合ピリジン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014503544A JP2014503544A (ja) | 2014-02-13 |
| JP2014503544A5 true JP2014503544A5 (https=) | 2015-01-15 |
| JP5684923B2 JP5684923B2 (ja) | 2015-03-18 |
Family
ID=45446116
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013545540A Active JP5684923B2 (ja) | 2010-12-20 | 2011-12-06 | カゼインキナーゼ阻害剤としての新規縮合ピリジン化合物 |
| JP2015005142A Active JP5876596B2 (ja) | 2010-12-20 | 2015-01-14 | カゼインキナーゼ阻害剤としての新規縮合ピリジン化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015005142A Active JP5876596B2 (ja) | 2010-12-20 | 2015-01-14 | カゼインキナーゼ阻害剤としての新規縮合ピリジン化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8536164B2 (https=) |
| EP (2) | EP2654750B1 (https=) |
| JP (2) | JP5684923B2 (https=) |
| KR (1) | KR101590236B1 (https=) |
| CN (1) | CN103260622B (https=) |
| AR (1) | AR084412A1 (https=) |
| AU (1) | AU2011346733C1 (https=) |
| CA (1) | CA2819961C (https=) |
| CY (2) | CY1118772T1 (https=) |
| DK (2) | DK3181133T3 (https=) |
| ES (2) | ES2744099T3 (https=) |
| HR (2) | HRP20170484T1 (https=) |
| HU (2) | HUE032405T2 (https=) |
| IL (1) | IL226948A (https=) |
| LT (2) | LT3181133T (https=) |
| MX (1) | MX338551B (https=) |
| PL (2) | PL2654750T3 (https=) |
| PT (2) | PT3181133T (https=) |
| RS (2) | RS59098B1 (https=) |
| SG (1) | SG190802A1 (https=) |
| SI (2) | SI3181133T1 (https=) |
| WO (1) | WO2012085721A1 (https=) |
| ZA (1) | ZA201303453B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2493876T1 (sl) * | 2009-10-28 | 2014-04-30 | Pfizer Inc. | Derivati imidazola kot inhibitorji kazein-kinaze |
| US9938269B2 (en) | 2011-06-30 | 2018-04-10 | Abbvie Inc. | Inhibitor compounds of phosphodiesterase type 10A |
| EP2935272B1 (en) * | 2012-12-21 | 2017-02-22 | Bristol-Myers Squibb Company | Pyrazole substituted imidazopyrazines as casein kinase 1 d/e inhibitors |
| WO2015163446A1 (ja) * | 2014-04-25 | 2015-10-29 | 協和発酵キリン株式会社 | イミダゾール化合物の製造方法 |
| JP2017222576A (ja) * | 2014-10-31 | 2017-12-21 | 石原産業株式会社 | 有害生物防除剤 |
| CN107365315B (zh) * | 2016-05-11 | 2024-08-09 | 国药集团国瑞药业有限公司 | 一种吡唑类化合物、其晶型及其制备方法 |
| US10973820B2 (en) * | 2017-12-13 | 2021-04-13 | Facio Intellectual Property B.V. | Compounds for treatment of diseases related to DUX4 expression |
| TW202112368A (zh) * | 2019-06-13 | 2021-04-01 | 荷蘭商法西歐知識產權股份有限公司 | 用於治療有關dux4表現之疾病的抑制劑組合 |
| CN115335057A (zh) * | 2020-03-27 | 2022-11-11 | 北京原基华毅生物科技有限公司 | 抑制酪蛋白激酶的方法 |
| EP4126878A4 (en) * | 2020-03-27 | 2024-07-10 | Gritscience Biopharmaceuticals Co., Ltd. | COMPOUNDS AS CASEIN KINASE INHIBITORS |
| AR122711A1 (es) | 2020-06-25 | 2022-09-28 | Alchemedicine Inc | COMPUESTO HETEROCÍCLICO COMO INHIBIDOR DE CASEÍNA QUINASA 1d Y/O QUINASA 5 TIPO RECEPTOR DE ACTIVINA |
| CN111808102B (zh) * | 2020-08-03 | 2021-12-31 | 南通大学 | 一种3-甲氧基-6,7-二氢-5H-吡咯并[3,4-b]吡啶盐酸盐及其合成方法 |
| JP2023541465A (ja) * | 2020-09-17 | 2023-10-02 | ヤンセン ファーマシューティカ エヌ．ベー． | カゼインキナーゼ１デルタモジュレーター |
| KR20230069169A (ko) * | 2020-09-17 | 2023-05-18 | 얀센 파마슈티카 엔.브이. | 카제인 키나제 1 델타 조절제 |
| EP4251149A4 (en) * | 2020-11-24 | 2024-10-30 | Merck Sharp & Dohme LLC | MODIFIED ISOINDOLINONES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS |
| CN116888126B (zh) * | 2020-12-15 | 2026-03-17 | 北京原基华毅生物科技有限公司 | 一种酪蛋白激酶抑制剂的化合物 |
| US20230053307A1 (en) * | 2021-07-19 | 2023-02-16 | Buddhist Tzu Chi Medical Foundation | Method for preventing or treating skin disorders and conditions |
| CN119487030A (zh) * | 2022-06-14 | 2025-02-18 | 北京原基华毅生物科技有限公司 | 作为酪蛋白激酶抑制剂的化合物的盐和/或晶形 |
| CN117362303B (zh) * | 2022-07-02 | 2026-02-03 | 黑龙江联顺生物科技有限公司 | 一种生物素中间体环酐的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0151962A3 (en) | 1984-01-25 | 1985-10-02 | Beecham Group Plc | Pyrazolopyridine derivatives |
| PL337020A1 (en) * | 1997-05-22 | 2000-07-31 | Searle & Co | Substituted pyrazoles as kinase p38 inhibitors |
| WO2001046196A1 (en) * | 1999-12-21 | 2001-06-28 | Sugen, Inc. | 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors |
| BRPI0612112A8 (pt) | 2005-06-22 | 2017-12-26 | Chemocentryx Inc | composto, composição farmacêutica, e, método de tratar doenças ou condições mediadas por ccr1. |
| WO2007140213A1 (en) | 2006-05-26 | 2007-12-06 | Forest Laboratories Holdings Limited | Pyridoazepine derivatives |
| EP2308866A1 (de) * | 2009-10-09 | 2011-04-13 | Bayer CropScience AG | Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide |
| SI2493876T1 (sl) * | 2009-10-28 | 2014-04-30 | Pfizer Inc. | Derivati imidazola kot inhibitorji kazein-kinaze |
-
2011
- 2011-12-06 LT LTEP17151228.8T patent/LT3181133T/lt unknown
- 2011-12-06 SG SG2013036934A patent/SG190802A1/en unknown
- 2011-12-06 ES ES17151228T patent/ES2744099T3/es active Active
- 2011-12-06 KR KR1020137015822A patent/KR101590236B1/ko not_active Expired - Fee Related
- 2011-12-06 WO PCT/IB2011/055489 patent/WO2012085721A1/en not_active Ceased
- 2011-12-06 CA CA2819961A patent/CA2819961C/en active Active
- 2011-12-06 PT PT17151228T patent/PT3181133T/pt unknown
- 2011-12-06 HU HUE11805210A patent/HUE032405T2/en unknown
- 2011-12-06 RS RS20191036A patent/RS59098B1/sr unknown
- 2011-12-06 SI SI201131784T patent/SI3181133T1/sl unknown
- 2011-12-06 SI SI201131141A patent/SI2654750T1/sl unknown
- 2011-12-06 HU HUE17151228A patent/HUE047089T2/hu unknown
- 2011-12-06 AU AU2011346733A patent/AU2011346733C1/en not_active Ceased
- 2011-12-06 PL PL11805210T patent/PL2654750T3/pl unknown
- 2011-12-06 JP JP2013545540A patent/JP5684923B2/ja active Active
- 2011-12-06 CN CN201180061257.2A patent/CN103260622B/zh active Active
- 2011-12-06 RS RS20170387A patent/RS55897B1/sr unknown
- 2011-12-06 DK DK17151228.8T patent/DK3181133T3/da active
- 2011-12-06 PL PL17151228T patent/PL3181133T3/pl unknown
- 2011-12-06 DK DK11805210.9T patent/DK2654750T3/en active
- 2011-12-06 LT LTEP11805210.9T patent/LT2654750T/lt unknown
- 2011-12-06 PT PT118052109T patent/PT2654750T/pt unknown
- 2011-12-06 ES ES11805210.9T patent/ES2623387T3/es active Active
- 2011-12-06 EP EP11805210.9A patent/EP2654750B1/en active Active
- 2011-12-06 MX MX2013005833A patent/MX338551B/es active IP Right Grant
- 2011-12-06 HR HRP20170484TT patent/HRP20170484T1/hr unknown
- 2011-12-06 EP EP17151228.8A patent/EP3181133B1/en active Active
- 2011-12-13 US US13/323,883 patent/US8536164B2/en active Active
- 2011-12-19 AR ARP110104787A patent/AR084412A1/es not_active Application Discontinuation
-
2013
- 2013-05-13 ZA ZA2013/03453A patent/ZA201303453B/en unknown
- 2013-06-13 IL IL226948A patent/IL226948A/en active IP Right Grant
-
2015
- 2015-01-14 JP JP2015005142A patent/JP5876596B2/ja active Active
-
2017
- 2017-03-27 CY CY20171100378T patent/CY1118772T1/el unknown
-
2019
- 2019-08-14 HR HRP20191469 patent/HRP20191469T1/hr unknown
- 2019-08-21 CY CY20191100892T patent/CY1122062T1/el unknown
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