JP2006524234A5 - - Google Patents
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- JP2006524234A5 JP2006524234A5 JP2006507614A JP2006507614A JP2006524234A5 JP 2006524234 A5 JP2006524234 A5 JP 2006524234A5 JP 2006507614 A JP2006507614 A JP 2006507614A JP 2006507614 A JP2006507614 A JP 2006507614A JP 2006524234 A5 JP2006524234 A5 JP 2006524234A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- compound
- composition according
- cosmetic composition
- metal cation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 150000001875 compounds Chemical class 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 13
- 239000002537 cosmetic Substances 0.000 claims 10
- 150000001768 cations Chemical class 0.000 claims 6
- 229910052751 metal Inorganic materials 0.000 claims 6
- 239000002184 metal Substances 0.000 claims 6
- 239000006071 cream Substances 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- 230000037303 wrinkles Effects 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 3
- 102000008186 Collagen Human genes 0.000 claims 3
- 108010035532 Collagen Proteins 0.000 claims 3
- 125000002252 acyl group Chemical group 0.000 claims 3
- -1 alkaline earth metal cation Chemical class 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 229920001436 collagen Polymers 0.000 claims 3
- 230000004936 stimulating effect Effects 0.000 claims 3
- 238000003786 synthesis reaction Methods 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 2
- 208000006770 Ascorbic Acid Deficiency Diseases 0.000 claims 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 2
- 239000004471 Glycine Substances 0.000 claims 2
- 229930003268 Vitamin C Natural products 0.000 claims 2
- 206010047623 Vitamin C deficiency Diseases 0.000 claims 2
- 230000003712 anti-aging effect Effects 0.000 claims 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims 2
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 claims 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 2
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 claims 2
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- YCOZIPAWZNQLMR-UHFFFAOYSA-N pentadecane Chemical compound CCCCCCCCCCCCCCC YCOZIPAWZNQLMR-UHFFFAOYSA-N 0.000 claims 2
- 229960003471 retinol Drugs 0.000 claims 2
- 235000020944 retinol Nutrition 0.000 claims 2
- 239000011607 retinol Substances 0.000 claims 2
- 208000010233 scurvy Diseases 0.000 claims 2
- 230000009469 supplementation Effects 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- SZHOJFHSIKHZHA-UHFFFAOYSA-N tridecanoic acid Chemical compound CCCCCCCCCCCCC(O)=O SZHOJFHSIKHZHA-UHFFFAOYSA-N 0.000 claims 2
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 claims 2
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 claims 2
- 235000019154 vitamin C Nutrition 0.000 claims 2
- 239000011718 vitamin C Substances 0.000 claims 2
- 230000002087 whitening effect Effects 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- XYHKNCXZYYTLRG-UHFFFAOYSA-N 1h-imidazole-2-carbaldehyde Chemical compound O=CC1=NC=CN1 XYHKNCXZYYTLRG-UHFFFAOYSA-N 0.000 claims 1
- GWYFCOCPABKNJV-UHFFFAOYSA-M 3-Methylbutanoic acid Natural products CC(C)CC([O-])=O GWYFCOCPABKNJV-UHFFFAOYSA-M 0.000 claims 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 239000005639 Lauric acid Substances 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010051246 Photodermatosis Diseases 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 claims 1
- 235000008206 alpha-amino acids Nutrition 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 230000001153 anti-wrinkle effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940114079 arachidonic acid Drugs 0.000 claims 1
- 235000021342 arachidonic acid Nutrition 0.000 claims 1
- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 210000000987 immune system Anatomy 0.000 claims 1
- 235000014705 isoleucine Nutrition 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 235000005772 leucine Nutrition 0.000 claims 1
- 235000019136 lipoic acid Nutrition 0.000 claims 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229910052744 lithium Inorganic materials 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000003094 microcapsule Substances 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 claims 1
- 239000002088 nanocapsule Substances 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- 235000017802 other dietary supplement Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 235000008729 phenylalanine Nutrition 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 235000019260 propionic acid Nutrition 0.000 claims 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 235000004400 serine Nutrition 0.000 claims 1
- 239000004334 sorbic acid Substances 0.000 claims 1
- 235000010199 sorbic acid Nutrition 0.000 claims 1
- 229940075582 sorbic acid Drugs 0.000 claims 1
- 238000005728 strengthening Methods 0.000 claims 1
- 230000000475 sunscreen effect Effects 0.000 claims 1
- 239000000516 sunscreening agent Substances 0.000 claims 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 claims 1
- 229960002663 thioctic acid Drugs 0.000 claims 1
- 235000002374 tyrosine Nutrition 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 0 *OC(C(*C1*C1)OC1=O)=C1O* Chemical compound *OC(C(*C1*C1)OC1=O)=C1O* 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46409703P | 2003-04-21 | 2003-04-21 | |
| PCT/IL2004/000343 WO2004094369A2 (en) | 2003-04-21 | 2004-04-21 | Stabilized derivatives of ascorbic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006524234A JP2006524234A (ja) | 2006-10-26 |
| JP2006524234A5 true JP2006524234A5 (enExample) | 2007-04-05 |
Family
ID=33310853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507614A Pending JP2006524234A (ja) | 2003-04-21 | 2004-04-21 | アスコルビン酸の安定化誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070167517A1 (enExample) |
| EP (1) | EP1620419A4 (enExample) |
| JP (1) | JP2006524234A (enExample) |
| KR (1) | KR20060008913A (enExample) |
| CN (1) | CN1805948A (enExample) |
| AU (1) | AU2004232556A1 (enExample) |
| BR (1) | BRPI0409628A (enExample) |
| CA (1) | CA2523042A1 (enExample) |
| MX (1) | MXPA05011269A (enExample) |
| WO (1) | WO2004094369A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050266064A1 (en) * | 2004-05-29 | 2005-12-01 | Mccarthy Kathryn J | Cosmetic compositions and methods |
| KR100691540B1 (ko) * | 2006-06-22 | 2007-03-12 | 주식회사 펩트론 | 펩타이드가 결합된 안정화된 비타민 c 유도체, 이의제조방법 및 이를 함유하는 조성물 |
| FR2904549B1 (fr) * | 2006-08-03 | 2012-12-14 | Sederma Sa | Composition comprenant de la sarsasapogenine |
| DE102006037724A1 (de) * | 2006-08-11 | 2008-02-14 | Merck Patent Gmbh | Verwendung von Ascorbinsäurederivaten zur Funktionalisierung von Matrices |
| US20080070883A1 (en) * | 2006-09-19 | 2008-03-20 | Wyeth | Use of LXR modulators for the prevention and treatment of skin aging |
| US20080095757A1 (en) * | 2006-10-23 | 2008-04-24 | Now Health Group, Inc. | Vitamin c compositions |
| FR2913686B1 (fr) * | 2007-03-14 | 2009-05-01 | Oreal | Nouveaux composes carbamates de vitamine c, compositions les comprenant, et utilisations |
| KR101056037B1 (ko) * | 2007-07-20 | 2011-08-10 | (주)바이오제닉스 | 알파-리포일기 함유 아스코르브산 유도체 및 그의 제조방법 |
| FR2946252B1 (fr) * | 2009-06-08 | 2011-07-29 | Fabre Pierre Dermo Cosmetique | Bis esters d'acide gras insature sur l'acide ascorbique et leurs utilisations cosmetiques |
| DE102009060543B4 (de) * | 2009-12-23 | 2014-02-06 | Axel Muntermann | Verfahren zur kosmetischen Hautglättung |
| US9387194B2 (en) * | 2012-01-18 | 2016-07-12 | Human Matrix Sciences, Llc | Sodium ascorbate stimulation of elastogenesis |
| WO2015048121A1 (en) * | 2013-09-25 | 2015-04-02 | University Of Florida Research Foundation, Inc. | Vitamin c prodrugs and uses thereof |
| CN103655223B (zh) * | 2013-11-14 | 2016-06-29 | 陕西东大生化科技有限责任公司 | 一种具有预防和治疗痤疮功效的制剂及其应用 |
| CN103896891A (zh) * | 2014-03-25 | 2014-07-02 | 李玉成 | 抗坏血酸锂及其制备方法 |
| KR102382346B1 (ko) * | 2019-01-11 | 2022-04-04 | 경북대학교 산학협력단 | 히알루론산 나노 입자를 합성하는 방법 및 이 방법으로 제조된 히알루론산 나노 입자 |
| CN110467689A (zh) * | 2019-09-09 | 2019-11-19 | 山东众山生物科技有限公司 | 一种透明质酸衍生物及其制备方法 |
| CN113527537B (zh) * | 2021-07-14 | 2022-04-08 | 润辉生物技术(威海)有限公司 | 一种左旋维生素c透明质酸酯衍生物及其制备方法和应用 |
| CN120172937B (zh) * | 2025-03-18 | 2026-02-17 | 上海珈凯生物股份有限公司 | 一种维生素c乙基醚的合成工艺 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA852614B (en) * | 1985-05-17 | 1986-10-09 | Takeda Chemical Industries, Ltd. | Ascorbic acid ethers and their production |
| CN1093360A (zh) * | 1992-10-02 | 1994-10-12 | 武田药品工业株式会社 | 2-o-烷基抗坏血酸的锂盐 |
| FR2715156B1 (fr) * | 1994-01-20 | 1996-03-01 | Oreal | Mono-esters d'acide cinnamique ou de ses dérivés et de vitamine C, leur procédé de préparation et leur utilisation comme anti-oxydants dans des compositions cosmétiques, pharmaceutiques ou alimentaires. |
| GB9403855D0 (en) * | 1994-03-01 | 1994-04-20 | Scotia Holdings Plc | Fatty acid derivatives |
| DE19750526A1 (de) * | 1997-11-14 | 1999-05-20 | Basf Ag | Ascorbinsäurederivate enthaltende kosmetische und pharmazeutische Zubereitungen |
| DE19750528A1 (de) * | 1997-11-14 | 1999-05-20 | Basf Ag | Ascorbylsorbate |
| JP4981198B2 (ja) * | 1998-03-31 | 2012-07-18 | 格 山本 | グリコシル−l−アスコルビン酸のアシル化誘導体 |
| FR2807320B1 (fr) * | 2000-04-10 | 2002-05-24 | Oreal | Utilisation de derives d'acide ascorbique pour augmenter la synthese des creramides epidermiques |
| DE60118625T2 (de) * | 2001-07-26 | 2007-02-22 | Tagra Biotechnologies Ltd. | Stabilisierte ascorbinsäure -3- phosphat- derivate |
| PL373522A1 (en) * | 2001-08-24 | 2005-09-05 | Matthias Rath | Novel ascorbic acid compounds, methods of synthesis and application use thereof |
| JP2004051535A (ja) * | 2002-07-19 | 2004-02-19 | Lion Corp | 口腔用組成物 |
-
2004
- 2004-04-21 BR BRPI0409628-2A patent/BRPI0409628A/pt not_active IP Right Cessation
- 2004-04-21 JP JP2006507614A patent/JP2006524234A/ja active Pending
- 2004-04-21 US US10/553,757 patent/US20070167517A1/en not_active Abandoned
- 2004-04-21 CA CA002523042A patent/CA2523042A1/en not_active Abandoned
- 2004-04-21 WO PCT/IL2004/000343 patent/WO2004094369A2/en not_active Ceased
- 2004-04-21 CN CNA2004800165028A patent/CN1805948A/zh active Pending
- 2004-04-21 KR KR1020057020056A patent/KR20060008913A/ko not_active Withdrawn
- 2004-04-21 EP EP04728625A patent/EP1620419A4/en not_active Withdrawn
- 2004-04-21 MX MXPA05011269A patent/MXPA05011269A/es unknown
- 2004-04-21 AU AU2004232556A patent/AU2004232556A1/en not_active Abandoned
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