|
US8563522B2
(en)
|
1997-07-08 |
2013-10-22 |
The Iams Company |
Method of maintaining and/or attenuating a decline in quality of life
|
|
US7381413B1
(en)
*
|
1998-04-17 |
2008-06-03 |
University Of Vermont And State Agricultural College |
Methods and products related to metabolic interactions in disease
|
|
EP1205493A1
(en)
*
|
2000-11-14 |
2002-05-15 |
ATOFINA Research |
Polymerisation catalyst systems and their preparation
|
|
US7666459B2
(en)
*
|
2001-09-12 |
2010-02-23 |
The Procter & Gamble Company |
Pet food compositions
|
|
US7547673B2
(en)
*
|
2001-09-13 |
2009-06-16 |
The Johns Hopkins University |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
|
|
EP1599196A4
(en)
*
|
2003-01-17 |
2006-05-31 |
Threshold Pharmaceuticals Inc |
COMBINATION THERAPIES FOR CANCER TREATMENT
|
|
US20050158294A1
(en)
|
2003-12-19 |
2005-07-21 |
The Procter & Gamble Company |
Canine probiotic Bifidobacteria pseudolongum
|
|
US8877178B2
(en)
|
2003-12-19 |
2014-11-04 |
The Iams Company |
Methods of use of probiotic bifidobacteria for companion animals
|
|
WO2005070126A2
(en)
*
|
2004-01-08 |
2005-08-04 |
The Regents Of The University Of Colorado |
Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
|
|
KR20120117943A
(ko)
|
2004-02-06 |
2012-10-24 |
쓰레솔드 파마슈티컬스, 인코포레이티드 |
항암 치료 방법
|
|
US20090252834A1
(en)
*
|
2004-05-10 |
2009-10-08 |
Michael Griffin Hayek |
Compositions comprising glucose anti-metabolites
|
|
JP2008502705A
(ja)
*
|
2004-06-17 |
2008-01-31 |
ウィスコンシン・アルムニ・リサーチ・ファウンデーション |
発作および発作性障害を処置するための化合物ならびに方法
|
|
WO2006024488A2
(en)
*
|
2004-08-30 |
2006-03-09 |
Interstitial Therapeutics |
Medical stent provided with inhibitors of atp synthesis
|
|
US20060078580A1
(en)
*
|
2004-10-08 |
2006-04-13 |
Mediquest Therapeutics, Inc. |
Organo-gel formulations for therapeutic applications
|
|
US7740875B2
(en)
*
|
2004-10-08 |
2010-06-22 |
Mediquest Therapeutics, Inc. |
Organo-gel formulations for therapeutic applications
|
|
BRPI0517268A
(pt)
*
|
2004-11-02 |
2008-10-07 |
Conforma Therapeutics Corp |
método para tratar uma forma de leucemia linfocìtica crÈnica
|
|
US8735394B2
(en)
|
2005-02-18 |
2014-05-27 |
Abraxis Bioscience, Llc |
Combinations and modes of administration of therapeutic agents and combination therapy
|
|
CN103169729A
(zh)
|
2005-02-18 |
2013-06-26 |
阿布拉科斯生物科学有限公司 |
治疗剂的组合和给予方式以及联合治疗
|
|
WO2006091790A1
(en)
|
2005-02-23 |
2006-08-31 |
Xenoport, Inc. |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
|
|
WO2006108681A2
(en)
|
2005-04-15 |
2006-10-19 |
Biomac Privatinstitut Für Medizinische Und Zahnmedizinische Forschung, Entwicklung Und Diagnostik Gmbh |
Substances and pharmaceutical compositions for the inhibition of glyoxalases and their use against bacteria
|
|
JP4938006B2
(ja)
|
2005-05-31 |
2012-05-23 |
ザ・アイムス・カンパニー |
ネコ科動物プロバイオティク・ビフィドバクテリア
|
|
EP2261323A1
(en)
|
2005-05-31 |
2010-12-15 |
The Iams Company |
Feline probiotic lactobacilli
|
|
US20060287253A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Kriegler Steven M |
Compounds and methods for treating seizure disorders
|
|
WO2006137595A1
(ja)
*
|
2005-06-24 |
2006-12-28 |
Takeda Pharmaceutical Company Limited |
Ｈｅｒ２発現癌の予防・治療薬
|
|
US20070032383A1
(en)
*
|
2005-07-27 |
2007-02-08 |
Newell M K |
Systems, methods, and compositions for modifying the metabolism of plants and of euucaryotic microbes
|
|
US20070134349A1
(en)
*
|
2005-09-19 |
2007-06-14 |
Duke University |
Methods of treating hematological malignancies
|
|
US8278349B2
(en)
|
2005-11-28 |
2012-10-02 |
Ramot At Tel-Aviv University Ltd. |
Cancer treatment using FTS and 2-deoxyglucose
|
|
WO2007067516A2
(en)
*
|
2005-12-06 |
2007-06-14 |
Duke University |
Multiple myeloma
|
|
US8324175B2
(en)
|
2006-02-16 |
2012-12-04 |
Young Hee Ko |
Compositions and methods for the treatment of cancer
|
|
US7754693B2
(en)
*
|
2006-02-16 |
2010-07-13 |
Young Hee Ko |
Composition and method for the efficacious and safe administration of halopyruvate for the treatment of cancer
|
|
EP1986660A4
(en)
*
|
2006-02-24 |
2009-08-26 |
Univ Texas |
HEXOSE COMPOUNDS FOR CANCER TREATMENT
|
|
CN101426508A
(zh)
*
|
2006-02-24 |
2009-05-06 |
得克萨斯系统大学评议会 |
治疗癌症的己糖化合物
|
|
US9149489B2
(en)
*
|
2006-04-27 |
2015-10-06 |
Board Of Regents, University Of Texas System |
Inhibitors of glycolysis useful in the treatment of brain tumors
|
|
WO2009108926A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Board Of Regents, The University Of Texas System |
Inhibitors of glycolysis useful in the treatment of brain tumors
|
|
AU2007246077A1
(en)
*
|
2006-05-03 |
2007-11-08 |
I.Q.A., A.S. |
Pharmaceutical composition containing taxane derivative destined for the preparation of an infusion solution, method of preparation thereof and use thereof
|
|
EP2161332B1
(en)
|
2006-11-20 |
2015-04-22 |
National University Corporation Kagawa University |
Deoxyketohexose isomerase and method for producing deoxyhexose and derivative thereof using same
|
|
EP2114413B1
(en)
*
|
2006-12-18 |
2014-10-22 |
The Johns Hopkins University |
Therapeutics for treating cancer using 3-bromopyruvate
|
|
WO2008093303A2
(en)
|
2007-02-01 |
2008-08-07 |
The Iams Company |
Method for decreasing inflammation and stress in a mammal using glucose antimetaboltes, avocado or avocado extracts
|
|
EP2156188B1
(en)
|
2007-03-28 |
2021-05-05 |
University of Southern California |
Induction of differential stress resistance and uses thereof
|
|
US8865646B2
(en)
*
|
2007-03-28 |
2014-10-21 |
University Of South California |
Dietary compositions and methods for protection against chemotherapy, radiotherapy, oxidative stress, and aging
|
|
RU2349271C2
(ru)
*
|
2007-03-29 |
2009-03-20 |
ФГУ Ростовский научно-исследовательский онкологический институт Росздрава |
Способ лечения рака прямой кишки
|
|
US8642067B2
(en)
|
2007-04-02 |
2014-02-04 |
Allergen, Inc. |
Methods and compositions for intraocular administration to treat ocular conditions
|
|
US8765690B2
(en)
*
|
2007-04-05 |
2014-07-01 |
Threshold Pharmaceuticals, Inc. |
Treatment of cancer with glufosfamide in patients not receiving insulin therapy
|
|
US20110091574A1
(en)
*
|
2008-02-15 |
2011-04-21 |
Catholic Healthcare West |
Treatment of adenocarcinoma expressing lkb1 with mtor inhibitor in combination with cox2 inhibitor
|
|
CA2716321A1
(en)
|
2008-02-21 |
2009-08-27 |
The Regents Of The University Of Colorado |
Methods for treating cancer using combination therapy
|
|
PL2282773T3
(pl)
|
2008-05-02 |
2014-08-29 |
Seattle Genetics Inc |
Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej
|
|
US20110183926A1
(en)
*
|
2008-05-23 |
2011-07-28 |
University Of Miami |
Treatment using continuous low dose application of sugar analogs
|
|
TW200950777A
(en)
*
|
2008-05-27 |
2009-12-16 |
Oncolytics Biotech Inc |
Abrogating proinflammatory cytokine production during oncolytic reovirus therapy
|
|
US9771199B2
(en)
|
2008-07-07 |
2017-09-26 |
Mars, Incorporated |
Probiotic supplement, process for making, and packaging
|
|
US8927506B2
(en)
*
|
2008-07-11 |
2015-01-06 |
Board Of Regents, The University Of Texas System |
Acetates of 2-deoxy monosaccharides with anticancer activity
|
|
US9073985B2
(en)
|
2008-07-14 |
2015-07-07 |
The Regents Of The University Of Colorado, A Body Corporate |
Methods and products for treating proliferative diseases
|
|
US20110207680A1
(en)
*
|
2008-08-13 |
2011-08-25 |
Curd John G |
Administration of Glufosfamide For The Treatment of Cancer
|
|
WO2010021750A2
(en)
*
|
2008-08-21 |
2010-02-25 |
The Johns Hopkins University |
Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
|
|
UA104147C2
(uk)
*
|
2008-09-10 |
2014-01-10 |
Новартис Аг |
Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
|
|
NZ594434A
(en)
*
|
2009-01-29 |
2014-11-28 |
Young Hee Ko |
Compositions and methods for the treatment of cancer
|
|
CN102985557B
(zh)
|
2009-03-13 |
2018-06-15 |
安吉奥斯医药品有限公司 |
用于细胞增殖相关病症的方法和组合物
|
|
PE20120693A1
(es)
|
2009-06-29 |
2012-07-04 |
Agios Pharmaceuticals Inc |
Compuestos heterociclos como moduladores de la piruvato cinasa m2 (pkm2)
|
|
US10104903B2
(en)
|
2009-07-31 |
2018-10-23 |
Mars, Incorporated |
Animal food and its appearance
|
|
US8450090B2
(en)
|
2009-10-06 |
2013-05-28 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods for promoting fatty acid production in plants
|
|
EP2525790B1
(en)
|
2009-10-21 |
2020-05-27 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
WO2011050210A1
(en)
*
|
2009-10-21 |
2011-04-28 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
SG10201406651PA
(en)
*
|
2009-10-22 |
2014-11-27 |
Propanc Pty Ltd |
A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent
|
|
CN102115483B
(zh)
*
|
2009-12-30 |
2014-12-17 |
苏州天人合生物技术有限公司 |
卤代双去氧糖衍生物及其制备方法与应用
|
|
GB2478556A
(en)
*
|
2010-03-09 |
2011-09-14 |
Myrovlytis Technology Ventures Ltd |
A composition for use in the treatment of Birt-Hogg-Dubô sydrome
|
|
US9393318B2
(en)
|
2010-03-29 |
2016-07-19 |
Abraxis Bioscience, Llc |
Methods of treating cancer
|
|
KR20130028727A
(ko)
|
2010-03-29 |
2013-03-19 |
아브락시스 바이오사이언스, 엘엘씨 |
치료제의 약물 전달 및 유효성 향상 방법
|
|
KR20130088116A
(ko)
|
2010-06-04 |
2013-08-07 |
아브락시스 바이오사이언스, 엘엘씨 |
췌장암의 치료 방법
|
|
EP3513794A3
(en)
|
2010-08-05 |
2019-10-16 |
Seattle Genetics, Inc. |
Fucose analogs for inhibition of protein fucosylation in vivo
|
|
WO2012049439A1
(en)
*
|
2010-10-13 |
2012-04-19 |
Imperial Innovations Limited |
Treatment of cancer/inhibition of metastasis
|
|
WO2012049440A1
(en)
*
|
2010-10-13 |
2012-04-19 |
Imperial Innovations Limited |
Treatment of cancer/inhibition of metastasis
|
|
WO2012097052A2
(en)
*
|
2011-01-11 |
2012-07-19 |
Intertech Bio, Llc |
Monosaccharide-based compounds for the treatment of proliferative and inflammatory dermatological diseases
|
|
WO2012123774A1
(en)
*
|
2011-03-11 |
2012-09-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Glycolytic inhibitor with cytotoxic agent for use in the treatment of a cancer
|
|
US20120238511A1
(en)
*
|
2011-03-14 |
2012-09-20 |
University Of Southern California |
2-deoxy-d-glucose formulations for prevention or treatment of neurodegenerative diseases
|
|
PT3406251T
(pt)
|
2011-05-03 |
2024-01-24 |
Agios Pharmaceuticals Inc |
Ativadores da piruvato-cinase para utilização em terapia
|
|
CN102827170A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
CN102827073A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
US20130196349A1
(en)
*
|
2011-08-02 |
2013-08-01 |
Realbio Technology, Inc. |
In Vitro Tumor Metastasis Model
|
|
KR101900478B1
(ko)
*
|
2011-08-04 |
2018-09-20 |
한올바이오파마주식회사 |
암의 재발 또는 전이의 억제용 약제학적 조성물
|
|
SMT201800334T1
(it)
|
2012-01-06 |
2018-09-13 |
Agios Pharmaceuticals Inc |
Composti terapeuticamente attivi e loro metodi di utilizzo
|
|
US9474779B2
(en)
|
2012-01-19 |
2016-10-25 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compositions and their methods of use
|
|
US20160015725A1
(en)
*
|
2012-02-14 |
2016-01-21 |
The Wistar Institute Of Anatomy And Biology |
Methods of controlling tumor bioenergetics networks
|
|
AU2013202693B2
(en)
*
|
2012-04-16 |
2015-01-22 |
Baxalta GmbH |
Combination Therapy of Anti-MIF Antibodies and Chemotherapeutics
|
|
EP2887947B1
(en)
|
2012-08-23 |
2019-06-05 |
Seattle Genetics, Inc. |
Fucose analogues for the treatment of sickle cell disease
|
|
WO2014062511A1
(en)
|
2012-10-15 |
2014-04-24 |
Agios Pharmaceuticals, Inc. |
Therapeutic compounds and compositions
|
|
WO2014072967A1
(en)
*
|
2012-11-12 |
2014-05-15 |
Urifer Ltd |
Drug combination comprising a glycolysis inhibitor and a tyrosine kinase inhibitor
|
|
KR101419816B1
(ko)
*
|
2013-01-30 |
2014-07-17 |
(주)제욱 |
상승적 치료 효과를 갖는 비소세포폐암의 예방 또는 치료용 조성물
|
|
ES2897699T3
(es)
|
2013-04-05 |
2022-03-02 |
Univ Texas |
Esteres de 2-desoxi-monosacáridos con actividad antiproliferativa
|
|
WO2015003360A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
CN105593215B
(zh)
|
2013-07-11 |
2019-01-15 |
安吉奥斯医药品有限公司 |
用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物
|
|
WO2015003355A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
WO2015010297A1
(en)
|
2013-07-25 |
2015-01-29 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
CA2936940C
(en)
|
2014-01-14 |
2023-07-04 |
The Johns Hopkins University |
Cyclodextrin compositions encapsulating a selective atp inhibitor and uses thereof
|
|
PH12021551647A1
(en)
|
2014-03-14 |
2022-06-06 |
Agios Pharmaceuticals Inc |
Pharmaceutical compositions of therapeutically active compounds
|
|
WO2016065353A1
(en)
*
|
2014-10-24 |
2016-04-28 |
University Of Miami |
Combination therapy with fenofibrate and 2-deoxyglucose or 2-deoxymannose
|
|
MX384883B
(es)
|
2015-06-11 |
2025-03-14 |
Agios Pharmaceuticals Inc |
Métodos para usar activadores de piruvato cinasa.
|
|
HUE067449T2
(hu)
|
2015-10-15 |
2024-10-28 |
Servier Lab |
Ivozidenib, citarabin és daunorubicin vagy idarubicin kombinációs terápa akut mielogén leukémia kezelésére
|
|
MD3362066T2
(ro)
|
2015-10-15 |
2022-08-31 |
Les Laboratoires Servier Sas |
Terapie combinată pentru tratamentul tumorilor maligne
|
|
WO2017079563A1
(en)
|
2015-11-06 |
2017-05-11 |
The Johns Hopkins University |
Methods of treating liver fibrosis by administering 3-bromopyruvate
|
|
HK1259489A1
(zh)
|
2015-11-12 |
2019-11-29 |
普罗潘克股份有限公司 |
酶原组合物
|
|
CN108697771A
(zh)
|
2016-01-29 |
2018-10-23 |
普罗潘克股份有限公司 |
癌症治疗
|
|
WO2017173360A2
(en)
*
|
2016-03-31 |
2017-10-05 |
Stcube, Inc. |
Combination treatments directed toward programmed death ligand-1 (pd-l1) positive cancers
|
|
JP6888239B2
(ja)
|
2017-06-28 |
2021-06-16 |
株式会社 ＳＥＮＴＡＮ Ｐｈａｒｍａ |
腫瘍治療用腫瘍免疫活性促進剤及び腫瘍治療用医薬組成物
|
|
BR112020001285A2
(pt)
|
2017-07-21 |
2020-07-28 |
Buck Institute For Research On Aging |
s-enantiômeros de beta-hidroxibutirato e butanodiol e métodos para sua utilização
|
|
US12037317B2
(en)
|
2018-01-25 |
2024-07-16 |
Buck Institute For Research On Aging |
Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
|
|
SMT202300073T1
(it)
|
2018-05-16 |
2023-05-12 |
Forma Therapeutics Inc |
Inibizione di idh-1 mutante
|
|
US11311527B2
(en)
|
2018-05-16 |
2022-04-26 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)
|
|
WO2019222551A1
(en)
|
2018-05-16 |
2019-11-21 |
Forma Therapeutics, Inc. |
Solid forms of ((s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile
|
|
US11013733B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1)
|
|
US11013734B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation
|
|
US10980788B2
(en)
|
2018-06-08 |
2021-04-20 |
Agios Pharmaceuticals, Inc. |
Therapy for treating malignancies
|
|
RU2707554C1
(ru)
*
|
2019-02-27 |
2019-11-28 |
Федеральное государственное бюджетное учреждение "Петербургский институт ядерной физики им. Б.П. Константинова Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт-ПИЯФ") |
Композиция, ингибирующая рост и выживаемость опухолевых клеток
|
|
IL296389A
(en)
|
2020-03-16 |
2022-11-01 |
Univ Texas |
Method of treating viral infections with hexose type monosaccharides and analogs thereof
|
|
WO2021211609A1
(en)
*
|
2020-04-16 |
2021-10-21 |
Buck Institute For Research On Aging |
Treatment of viral pathologies with exogenous ketones
|
|
CA3200999A1
(en)
*
|
2020-12-14 |
2022-06-23 |
Miguel Angel Barajas Velez |
Compositions comprising bacteria for cancer immunotherapy
|
|
WO2023062516A1
(en)
*
|
2021-10-11 |
2023-04-20 |
Exploration Invest Pte Ltd |
2-deoxy-d-glucose for use in disease therapy
|
|
CN114617876B
(zh)
*
|
2022-01-28 |
2023-04-07 |
四川大学华西医院 |
一种抗肿瘤联合用药物
|
|
KR102980182B1
(ko)
|
2022-09-16 |
2026-06-19 |
이화여자대학교 산학협력단 |
해당과정 억제제 및 미토콘드리아 기능 억제제를 포함하는 암의 예방 또는 치료용 약학적 조성물
|
|
EP4582080A1
(en)
|
2024-01-02 |
2025-07-09 |
G.ST Antivirals GmbH |
Dispenser for mucosal administration comprising 2-deoxy-glucose or analogues thereof
|