SG10201406651PA - A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent - Google Patents

A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent

Info

Publication number
SG10201406651PA
SG10201406651PA SG10201406651PA SG10201406651PA SG10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA
Authority
SG
Singapore
Prior art keywords
orchymotrypsinogen
compoundand
trypsinogen
vanilloid
pharmaceutical composition
Prior art date
Application number
SG10201406651PA
Inventor
Julian Norman Kenyon
Paul Rodney Clayton
David Tosh
Fernando Felquer
Ralf Brandt
Original Assignee
Propanc Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009905147A external-priority patent/AU2009905147A0/en
Application filed by Propanc Pty Ltd filed Critical Propanc Pty Ltd
Publication of SG10201406651PA publication Critical patent/SG10201406651PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
SG10201406651PA 2009-10-22 2010-10-22 A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent SG10201406651PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009905147A AU2009905147A0 (en) 2009-10-22 Pharmaceutical Compositions
AU2010902655A AU2010902655A0 (en) 2010-06-17 Cancer Cell Regulation

Publications (1)

Publication Number Publication Date
SG10201406651PA true SG10201406651PA (en) 2014-11-27

Family

ID=43899732

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201406651PA SG10201406651PA (en) 2009-10-22 2010-10-22 A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent

Country Status (22)

Country Link
US (4) US9636359B2 (en)
EP (2) EP3095458B1 (en)
JP (1) JP5871805B2 (en)
KR (1) KR101936439B1 (en)
CN (2) CN102639145B (en)
AU (1) AU2010310887B9 (en)
BR (1) BR112012009521B1 (en)
CA (1) CA2814958C (en)
CL (1) CL2012001019A1 (en)
DK (1) DK3095458T3 (en)
ES (1) ES2692377T3 (en)
HK (1) HK1249017A1 (en)
IL (1) IL219216A (en)
MX (1) MX355971B (en)
NZ (1) NZ599996A (en)
PE (1) PE20121709A1 (en)
PT (1) PT3095458T (en)
RU (1) RU2012120785A (en)
SG (1) SG10201406651PA (en)
TR (1) TR201815315T4 (en)
WO (1) WO2011047434A1 (en)
ZA (1) ZA201203689B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20121709A1 (en) 2009-10-22 2012-12-17 Propanc Pty Ltd A PHARMACEUTICAL COMPOSITION TO TREAT CANCER INCLUDING TRYPSINOGEN AND / OR CHEMOTRIPSINOGEN AND AN ACTIVE AGENT SELECTED FROM A SELENIUM COMPOUND, A VAINILLOID COMPOUND AND A CYTOPLASMIC GLYCOLYSIS REDUCING AGENT
CN105377271A (en) * 2013-03-15 2016-03-02 全技术公司 Compositions comprising selenium and use of same for the treatment and prevention of disease or conditions associated with mitochondrial dysfunction
CZ307195B6 (en) 2013-11-18 2018-03-14 František Trnka A pharmaceutical composition comprising a mixture of proenzymes and enzymes
MX2016011897A (en) * 2014-03-14 2017-04-27 Alltech Inc Compositions of selenoorganic compounds and methods of use thereof.
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US20160106721A1 (en) 2014-10-21 2016-04-21 Life Plus, LLC Human therapeutic agents
NZ742020A (en) 2015-11-12 2022-10-28 Propanc Pty Ltd Proenzyme composition
WO2017127892A1 (en) 2016-01-29 2017-08-03 Propanc Pty Ltd Cancer treatment
AU2017250010A1 (en) 2016-04-12 2018-10-11 Propanc Pty Ltd Composition of proenzymes for cancer treatment
EP3517117A1 (en) * 2018-01-30 2019-07-31 Medizinische Universität Wien Medicament for prevention or treatment of rhinovirus infection
WO2022261440A1 (en) * 2021-06-11 2022-12-15 Sorrento Therapeutics, Inc. Administration of resiniferatoxin for treatment of pancreatic cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514388A (en) * 1983-03-22 1985-04-30 Psaledakis Nicholas G Proteolytic enzymes in the zymogen form to treat sarcoma cells
US4978332A (en) * 1987-09-28 1990-12-18 Matrix Pharmaceutical, Inc. Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
FR2727107B1 (en) * 1994-11-21 1996-12-27 Saint Gobain Vitrage GLAZING PROVIDED WITH AT LEAST ONE THIN FILM AND PROCESS FOR OBTAINING SAME
CZ283972B6 (en) * 1995-05-17 1998-07-15 František Mudr. Trnka Pharmaceutical preparation exhibiting modulation effect on malignant tumors and the use thereof
CN1121218C (en) * 2000-03-08 2003-09-17 台湾东洋药品工业股份有限公司 Medicine composition for treating hepatocellular carcinoma
US6670330B1 (en) * 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
AU2002226650A1 (en) * 2001-01-18 2002-07-30 Arnold Hoffman Redox therapy for tumors
CN1471925A (en) * 2002-08-02 2004-02-04 丛繁滋 Arsenic contained composition for directly hard tumour medoicine feed, preparation, preparing method thereof
JP2004182674A (en) * 2002-12-05 2004-07-02 Kureha Chem Ind Co Ltd Antineoplastic medicinal composition containing vanillyl fatty acid amide
BRPI0406667A (en) * 2003-01-10 2005-12-20 Threshold Pharmaceuticals Inc Method for treating cancer, and therapeutically acceptable formulation of 2-dg
JP2006528696A (en) * 2003-05-13 2006-12-21 ヘルス リサーチ インコーポレイテッド Method for enhancing antitumor activity of anticancer agent
DE10321725A1 (en) * 2003-05-14 2004-12-02 Mucos Pharma Gmbh & Co Enzyme-containing compositions, dietetic foods and pharmaceuticals made therefrom and their use for medical purposes
CN1557482A (en) * 2004-02-04 2004-12-29 高春平 Immune function regulating and tumor resisting natural nutrient
JP2006151965A (en) * 2004-10-28 2006-06-15 Mi Tec:Kk Seleniferous composition and method for producing the same
CN101287481A (en) * 2005-05-26 2008-10-15 科学工业研究委员会 A pharmaceutical composition useful for the treatment of hepatocellular carcinoma
KR100740989B1 (en) 2005-07-22 2007-07-19 넨시스(주) Spherical anti-inflammatory and anti-cancer enzyme granules and method for preparing the same
CN1944641B (en) * 2006-10-26 2010-11-03 上海林叶生物科技有限公司 Method for preparing high purity chymotrypsin
KR101058136B1 (en) * 2007-11-09 2011-08-24 신동헌 New Uses of Capsate or Dihydrocapsate
PE20121709A1 (en) 2009-10-22 2012-12-17 Propanc Pty Ltd A PHARMACEUTICAL COMPOSITION TO TREAT CANCER INCLUDING TRYPSINOGEN AND / OR CHEMOTRIPSINOGEN AND AN ACTIVE AGENT SELECTED FROM A SELENIUM COMPOUND, A VAINILLOID COMPOUND AND A CYTOPLASMIC GLYCOLYSIS REDUCING AGENT
CZ307195B6 (en) * 2013-11-18 2018-03-14 František Trnka A pharmaceutical composition comprising a mixture of proenzymes and enzymes

Also Published As

Publication number Publication date
US20230137573A1 (en) 2023-05-04
WO2011047434A1 (en) 2011-04-28
BR112012009521B1 (en) 2021-07-13
US20180064753A1 (en) 2018-03-08
RU2012120785A (en) 2013-11-27
CN102639145A (en) 2012-08-15
ES2692377T3 (en) 2018-12-03
DK3095458T3 (en) 2018-11-19
CA2814958C (en) 2023-09-26
BR112012009521A2 (en) 2016-05-17
EP3095458B1 (en) 2018-07-25
IL219216A (en) 2017-03-30
EP2490711A1 (en) 2012-08-29
CA2814958A1 (en) 2011-04-28
EP2490711A4 (en) 2013-04-03
IL219216A0 (en) 2012-06-28
AU2010310887B2 (en) 2015-09-03
PE20121709A1 (en) 2012-12-17
CN107625957B (en) 2021-06-15
MX2012004610A (en) 2012-11-12
EP3095458A1 (en) 2016-11-23
KR101936439B1 (en) 2019-01-08
US9636359B2 (en) 2017-05-02
US20190388463A1 (en) 2019-12-26
JP2013508307A (en) 2013-03-07
NZ599996A (en) 2014-06-27
CN102639145B (en) 2017-09-26
KR20120128124A (en) 2012-11-26
AU2010310887B9 (en) 2015-10-08
MX355971B (en) 2018-05-07
ZA201203689B (en) 2013-02-27
PT3095458T (en) 2018-11-09
JP5871805B2 (en) 2016-03-01
HK1249017A1 (en) 2018-10-26
CL2012001019A1 (en) 2013-07-12
AU2010310887A1 (en) 2012-06-07
TR201815315T4 (en) 2018-11-21
US10350239B2 (en) 2019-07-16
CN107625957A (en) 2018-01-26
US20120251516A1 (en) 2012-10-04

Similar Documents

Publication Publication Date Title
SG10201406651PA (en) A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent
LTPA2020520I1 (en) Anti-CD38 plus corticosteroids, plus non-corticosteroid chemotherapeutic agent for cancer treatment
IL255752B (en) Compounds, pharmaceutical compositions comprising the same and uses thereof for treating cardiovasclar disease, an inflammatory disease or cancer
IL251637A0 (en) Pharmaceutical compositions comprising a pd-1 antagonist for treating infections and tumors
HK1204277A1 (en) Compositions and methods for treating demodex infestations
IL226327A (en) Neprilysin inhibitors, pharmaceutical compositions comprising them and uses thereof for preparing such compositions
PL2532364T3 (en) Pharmaceutical composition comprising anti caprin-1 antibodies for treating and/or preventing cancer
PL2532366T3 (en) Pharmaceutical composition for treating and/or preventing cancer
IL197121A0 (en) Systems for programmable delivery of an active agent
BRPI0922475A2 (en) compound, pharmaceutical composition, method for treating cancer, and use of a compound.
BRPI0720546A2 (en) Compound, inhibitor, drug, antitumor agent, pharmaceutical composition, method for treating cancer, and compound use
EP2093237A4 (en) Cancer therapeutic agent comprising anti-hb-egf antibody as active ingredient
HK1200187A1 (en) Humanized anti-epiregulin antibody, and cancer therapeutic agent comprising said antibody as active ingredient
EP2531025A4 (en) Method for treating fungal infections, fungicidal compositions and their use
IL205401A0 (en) An orally - absorbed solid dose formulation for vancomycin
IL197212A0 (en) Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
PT2327672T (en) Plaster-based material including an agent capable of trapping formaldehyde.
BRPI0908635A2 (en) compound, pharmaceutical composition and cancer treatment method
BRPI1007334A2 (en) compound, inhibitor, drug, pharmaceutical composition, use of a compound, anticancer agent, and method for treating cancer.
HK1162138A1 (en) Skin-whitening agent, anti-aging agent, and anti-oxidant agent
IL222707B (en) 16-chloro- and 16,16-dichloro-(4a,4ß)-17ß-(2-oxo-2h-pyran-5-yl) steroid compounds and pharmaceutical compositions comprising them
EP2910246A4 (en) Pharmaceutical composition for preventing or treating cancer, containing enoblock as active ingredient
EP2473506A4 (en) Compounds and compositions for treating cancer
PL2379056T3 (en) Solid pharmaceutical composition comprising at least one stabilizing agent
EP2150243A4 (en) Compositions and methods for enhancing active agent absorption