JP2006514948A5 - - Google Patents
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- Publication number
- JP2006514948A5 JP2006514948A5 JP2004560214A JP2004560214A JP2006514948A5 JP 2006514948 A5 JP2006514948 A5 JP 2006514948A5 JP 2004560214 A JP2004560214 A JP 2004560214A JP 2004560214 A JP2004560214 A JP 2004560214A JP 2006514948 A5 JP2006514948 A5 JP 2006514948A5
- Authority
- JP
- Japan
- Prior art keywords
- cyanomethyl
- alkyl
- pyrimidin
- amino
- leucine amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0203712A SE0203712D0 (sv) | 2002-12-13 | 2002-12-13 | Novel compounds |
| PCT/SE2003/001931 WO2004054987A1 (en) | 2002-12-13 | 2003-12-11 | Cathepsin cysteine protease inhibitors and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514948A JP2006514948A (ja) | 2006-05-18 |
| JP2006514948A5 true JP2006514948A5 (enExample) | 2007-02-01 |
Family
ID=20289870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004560214A Pending JP2006514948A (ja) | 2002-12-13 | 2003-12-11 | カテプシン・システイン・プロテアーゼ阻害剤とその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7605159B2 (enExample) |
| EP (1) | EP1572667B1 (enExample) |
| JP (1) | JP2006514948A (enExample) |
| AT (1) | ATE361914T1 (enExample) |
| AU (1) | AU2003303076A1 (enExample) |
| DE (1) | DE60313803T2 (enExample) |
| ES (1) | ES2285273T3 (enExample) |
| SE (1) | SE0203712D0 (enExample) |
| WO (1) | WO2004054987A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005316599A1 (en) * | 2004-12-14 | 2006-06-22 | Vertex Pharmaceuticals Incorporated | Pyrimidine inhibitors of ERK protein kinase and uses therof |
| EP2170879B1 (en) | 2007-06-26 | 2013-01-16 | AstraZeneca AB | 1-cyanocyclopropyl-derivatives as cathepsin k inhibitors |
| WO2011025799A1 (en) * | 2009-08-26 | 2011-03-03 | Glaxo Group Limited | Cathepsin c inhibitors |
| CR20170076A (es) | 2014-08-04 | 2017-06-26 | Nuevolution As | Derivados de pirimidima sustituidos con heterociclilo opcionalmente condensados útiles para el tratamiento de enfermedades inflamatorias, metabólicas, oncológicas y autoinmunitarias |
| EA202092442A3 (ru) | 2016-06-07 | 2021-08-31 | Джакобио Фармасьютикалс Ко., Лтд. | Новые гетероциклические производные, применимые в качестве ингибиторов shp2 |
| MA45244A (fr) | 2016-06-13 | 2019-04-17 | Cancer Research Tech Ltd | Pyridines substituées utilisées en tant qu'inhibiteurs de dnmt1 |
| WO2018172984A1 (en) | 2017-03-23 | 2018-09-27 | Jacobio Pharmaceuticals Co., Ltd. | Novel heterocyclic derivatives useful as shp2 inhibitors |
| CN112839935A (zh) | 2018-09-26 | 2021-05-25 | 北京加科思新药研发有限公司 | 可用作shp2抑制剂的新型杂环衍生物 |
| AU2020250933A1 (en) | 2019-04-05 | 2021-10-28 | Centre Hospitalier Régional Et Universitaire De Brest | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning |
| AU2020408107B2 (en) | 2019-12-20 | 2026-04-23 | Nuevolution A/S | Compounds active towards nuclear receptors |
| AU2020405446A1 (en) | 2019-12-20 | 2022-05-26 | Nuevolution A/S | Compounds active towards nuclear receptors |
| EP4126874A1 (en) | 2020-03-31 | 2023-02-08 | Nuevolution A/S | Compounds active towards nuclear receptors |
| US11613532B2 (en) | 2020-03-31 | 2023-03-28 | Nuevolution A/S | Compounds active towards nuclear receptors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6313117B1 (en) | 1999-07-30 | 2001-11-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Succinate derivative compounds useful as cysteine protease inhibitors |
| JP2003525874A (ja) | 2000-01-06 | 2003-09-02 | メルク フロスト カナダ アンド カンパニー | プロテアーゼ阻害剤としての新規化合物および組成物 |
| AU2001245764A1 (en) | 2000-03-15 | 2001-09-24 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions as protease inhibitors |
| JP4365094B2 (ja) * | 2001-03-02 | 2009-11-18 | メルク フロスト カナダ リミテツド | カテプシンシステインプロテアーゼ阻害薬 |
| KR20050044660A (ko) | 2001-12-04 | 2005-05-12 | 에프. 호프만-라 로슈 아게 | 치환된 2-아미노-사이클로알칸카복스아마이드 및 시스테인프로테아제 저해제로서의 이의 용도 |
| ES2364046T3 (es) | 2002-12-19 | 2011-08-23 | Bristol-Myers Squibb Company | Gamma-carbolinas tricíclicas sustituidas utilizadas como agonistas y antagonistas de los receptores de la serotonina. |
-
2002
- 2002-12-13 SE SE0203712A patent/SE0203712D0/xx unknown
-
2003
- 2003-12-11 US US10/538,452 patent/US7605159B2/en not_active Expired - Fee Related
- 2003-12-11 DE DE60313803T patent/DE60313803T2/de not_active Expired - Lifetime
- 2003-12-11 EP EP03813325A patent/EP1572667B1/en not_active Expired - Lifetime
- 2003-12-11 JP JP2004560214A patent/JP2006514948A/ja active Pending
- 2003-12-11 AU AU2003303076A patent/AU2003303076A1/en not_active Abandoned
- 2003-12-11 ES ES03813325T patent/ES2285273T3/es not_active Expired - Lifetime
- 2003-12-11 AT AT03813325T patent/ATE361914T1/de not_active IP Right Cessation
- 2003-12-11 WO PCT/SE2003/001931 patent/WO2004054987A1/en not_active Ceased
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