JP2006512318A5 - - Google Patents
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- Publication number
- JP2006512318A5 JP2006512318A5 JP2004551638A JP2004551638A JP2006512318A5 JP 2006512318 A5 JP2006512318 A5 JP 2006512318A5 JP 2004551638 A JP2004551638 A JP 2004551638A JP 2004551638 A JP2004551638 A JP 2004551638A JP 2006512318 A5 JP2006512318 A5 JP 2006512318A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- retinal
- neovascularization
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42557402P | 2002-11-12 | 2002-11-12 | |
| PCT/US2003/034617 WO2004043352A2 (en) | 2002-11-12 | 2003-10-30 | Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006512318A JP2006512318A (ja) | 2006-04-13 |
| JP2006512318A5 true JP2006512318A5 (https=) | 2006-07-13 |
Family
ID=32313018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004551638A Pending JP2006512318A (ja) | 2002-11-12 | 2003-10-30 | 眼の血管新生もしくは水腫状の疾患および障害を処置するためのヒストンデアセチラーゼインヒビター |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20060074100A1 (https=) |
| EP (1) | EP1560583A4 (https=) |
| JP (1) | JP2006512318A (https=) |
| KR (1) | KR20050086526A (https=) |
| CN (1) | CN1711087A (https=) |
| AU (1) | AU2003287349B2 (https=) |
| BR (1) | BR0316206A (https=) |
| CA (1) | CA2504460A1 (https=) |
| MX (1) | MXPA05004485A (https=) |
| RU (1) | RU2352337C2 (https=) |
| WO (1) | WO2004043352A2 (https=) |
| ZA (1) | ZA200503237B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| JP2006512318A (ja) * | 2002-11-12 | 2006-04-13 | アルコン，インコーポレイテッド | 眼の血管新生もしくは水腫状の疾患および障害を処置するためのヒストンデアセチラーゼインヒビター |
| CA2518318A1 (en) | 2003-03-17 | 2004-09-30 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| CN1839121A (zh) * | 2003-04-01 | 2006-09-27 | 斯隆-凯特林癌症研究所 | 异羟肟酸化合物及其使用方法 |
| US20050197336A1 (en) * | 2004-03-08 | 2005-09-08 | Miikana Therapeutics Corporation | Inhibitors of histone deacetylase |
| US7345043B2 (en) * | 2004-04-01 | 2008-03-18 | Miikana Therapeutics | Inhibitors of histone deacetylase |
| KR20070057822A (ko) * | 2004-08-09 | 2007-06-07 | 아스텔라스세이야쿠 가부시키가이샤 | 히스톤 디아세틸라제 (ｈｄａｃ) 억제제 활성을 갖는히드록시아미드 화합물 |
| JP2008524246A (ja) | 2004-12-16 | 2008-07-10 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| CA2596015A1 (en) | 2005-02-14 | 2006-08-24 | Sampath K. Anandan | Fused heterocyclic compounds useful as inhibitors of histone deacetylase |
| GB0509225D0 (en) * | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Inhibitors of enzymatic activity |
| BRPI0610368A8 (pt) | 2005-05-05 | 2015-09-08 | Glaxosmithkline Ip Dev Ltd | Modulação de enzima e de receptor |
| US7642253B2 (en) | 2005-05-11 | 2010-01-05 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| EA200800321A1 (ru) * | 2005-07-14 | 2008-06-30 | Такеда Сан Диего, Инк. | Ингибиторы гистондеацетилазы |
| AU2006272497B2 (en) * | 2005-07-27 | 2012-07-19 | University Of Florida Research Foundation, Inc. | Small compounds that correct protein misfolding and uses thereof |
| KR20080091297A (ko) * | 2006-02-07 | 2008-10-09 | 아스텔라스세이야쿠 가부시키가이샤 | Ｎ-히드록시아크릴아미드 화합물 |
| WO2007113644A2 (en) * | 2006-04-05 | 2007-10-11 | Orchid Research Laboratories Limited | New hdac inhibitors |
| US8962825B2 (en) * | 2006-10-30 | 2015-02-24 | Glaxosmithkline Intellectual Property Development Limited | Hydroxamates as inhibitors of histone deacetylase |
| JP2010513223A (ja) * | 2006-12-15 | 2010-04-30 | アステラス製薬株式会社 | Ｎ−ヒドロキシアクリルアミド化合物 |
| CN101239929B (zh) * | 2007-02-09 | 2013-04-17 | 中国科学院上海药物研究所 | 曲古抑菌素a衍生物及其制备方法和用途 |
| JP2008266321A (ja) * | 2007-03-28 | 2008-11-06 | Santen Pharmaceut Co Ltd | フェニレンジアミン誘導体を有効成分とする眼圧下降剤 |
| KR102341446B1 (ko) * | 2016-09-29 | 2021-12-21 | 네이처와이즈 바이오테크 & 메디칼스 코포레이션 | 안구 질병을 치료하는 방법 |
| WO2019089573A1 (en) * | 2017-10-30 | 2019-05-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Treatment of ocular conditions utilizing a histone/protein deacetylase inhibitor |
| KR102236356B1 (ko) | 2017-11-24 | 2021-04-05 | 주식회사 종근당 | 루푸스의 예방 또는 치료를 위한 조성물 |
| KR20190099952A (ko) * | 2018-02-20 | 2019-08-28 | 주식회사 종근당 | 포도막염의 예방 또는 치료를 위한 조성물 |
| WO2019246509A1 (en) * | 2018-06-22 | 2019-12-26 | Mohan Rajiv R | Methods and compositions for promoting wound healing with decreased scar formation after glaucoma filtration surgery |
| WO2020102599A1 (en) * | 2018-11-14 | 2020-05-22 | Vanderbilt University | Treating intraocular retinoblastoma with inhibitors of histone modification |
| RU2769320C1 (ru) * | 2020-12-28 | 2022-03-30 | Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) | Способ получения производных N-гидроксибутанамида |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975537A (en) * | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
| US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
| US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
| GB9804504D0 (en) * | 1998-03-03 | 1998-04-29 | Leo Pharm Prod Ltd | Matrix metalloproteinase inhibitors |
| AUPP505798A0 (en) * | 1998-08-04 | 1998-08-27 | Fujisawa Pharmaceutical Co., Ltd. | Novel compound fr225497 substance |
| BR9914779A (pt) * | 1998-10-13 | 2001-07-03 | Fujisawa Pharmaceutical Co | Composto wf27082, processo para sua produção, composição farmacêutica contendo o mesmo, cepa de fundos pertencente ao gênero acremonium, composto tendo atividade inibidora de desacetilase de histona, processo para sua produção, seu método e uso |
| US6953783B1 (en) * | 1998-10-19 | 2005-10-11 | Methylgene, Inc. | Modulation of gene expression by combination therapy |
| EP1167346A4 (en) * | 1999-04-06 | 2003-07-23 | Ono Pharmaceutical Co | DERIVATIVES OF 4-AMINOBUTANIC ACID AND MEDICINES THAT CONTAIN THESE DERIVATIVES AS ACTIVE ACTIVE SUBSTANCES |
| EA200601252A1 (ru) * | 1999-09-08 | 2006-10-27 | Слоан-Кеттеринг Инститьют Фор Кэнсер Рисёч | Новый класс веществ, вызывающих дифференцировку клеток и являющихся ингибиторами гистондеацетилазы, и способы их применения |
| US6544957B2 (en) * | 2000-01-04 | 2003-04-08 | The Johns Hopkins University | Methods and reagents for facilitating transcription |
| AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| GB0023983D0 (en) * | 2000-09-29 | 2000-11-15 | Prolifix Ltd | Therapeutic compounds |
| RU2177801C1 (ru) * | 2001-01-25 | 2002-01-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Средство, ингибирующее ангиогенез при заболеваниях органа зрения |
| JPWO2002074298A1 (ja) * | 2001-03-21 | 2004-07-08 | 小野薬品工業株式会社 | Ｉｌ−６産生阻害剤 |
| US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
| EP1443928B1 (en) * | 2001-10-16 | 2011-07-27 | Sloan-Kettering Institute For Cancer Research | Treatment of neurodegenerative diseases and cancer of the brain |
| US7154002B1 (en) * | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| JP2006512318A (ja) * | 2002-11-12 | 2006-04-13 | アルコン，インコーポレイテッド | 眼の血管新生もしくは水腫状の疾患および障害を処置するためのヒストンデアセチラーゼインヒビター |
| US20080004311A1 (en) * | 2002-11-12 | 2008-01-03 | Alcon, Inc. | Histone deacetylase inhibitors for treating degenerative diseases of the eye |
| CN1711086A (zh) * | 2002-11-12 | 2005-12-21 | 爱尔康公司 | 用于治疗眼的退化性疾病的组蛋白脱乙酰酶抑制剂 |
-
2003
- 2003-10-30 JP JP2004551638A patent/JP2006512318A/ja active Pending
- 2003-10-30 CA CA002504460A patent/CA2504460A1/en not_active Abandoned
- 2003-10-30 EP EP03781581A patent/EP1560583A4/en not_active Withdrawn
- 2003-10-30 AU AU2003287349A patent/AU2003287349B2/en not_active Ceased
- 2003-10-30 CN CNA2003801030038A patent/CN1711087A/zh active Pending
- 2003-10-30 BR BR0316206-0A patent/BR0316206A/pt not_active Application Discontinuation
- 2003-10-30 WO PCT/US2003/034617 patent/WO2004043352A2/en not_active Ceased
- 2003-10-30 KR KR1020057008413A patent/KR20050086526A/ko not_active Ceased
- 2003-10-30 MX MXPA05004485A patent/MXPA05004485A/es active IP Right Grant
- 2003-10-30 US US10/531,754 patent/US20060074100A1/en not_active Abandoned
- 2003-10-30 US US10/697,135 patent/US20040092558A1/en not_active Abandoned
- 2003-10-30 RU RU2005118107/14A patent/RU2352337C2/ru not_active IP Right Cessation
-
2005
- 2005-04-21 ZA ZA200503237A patent/ZA200503237B/en unknown
-
2009
- 2009-10-30 US US12/609,873 patent/US20100048608A1/en not_active Abandoned
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