JP2006509751A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006509751A5 JP2006509751A5 JP2004554308A JP2004554308A JP2006509751A5 JP 2006509751 A5 JP2006509751 A5 JP 2006509751A5 JP 2004554308 A JP2004554308 A JP 2004554308A JP 2004554308 A JP2004554308 A JP 2004554308A JP 2006509751 A5 JP2006509751 A5 JP 2006509751A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- composition
- composition according
- incontinence
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 17
- 206010069632 Bladder dysfunction Diseases 0.000 claims 5
- 206010046543 Urinary incontinence Diseases 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- ZEUITGRIYCTCEM-KRWDZBQOSA-N (S)-duloxetine Chemical compound C1([C@@H](OC=2C3=CC=CC=C3C=CC=2)CCNC)=CC=CS1 ZEUITGRIYCTCEM-KRWDZBQOSA-N 0.000 claims 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 229960002866 duloxetine Drugs 0.000 claims 3
- -1 fluparoxane Chemical compound 0.000 claims 3
- 206010020853 Hypertonic bladder Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010053236 Mixed incontinence Diseases 0.000 claims 2
- 208000009722 Overactive Urinary Bladder Diseases 0.000 claims 2
- 206010066218 Stress Urinary Incontinence Diseases 0.000 claims 2
- 208000000921 Urge Urinary Incontinence Diseases 0.000 claims 2
- 208000015114 central nervous system disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 208000020629 overactive bladder Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims 2
- 208000022170 stress incontinence Diseases 0.000 claims 2
- 206010046494 urge incontinence Diseases 0.000 claims 2
- GJJFMKBJSRMPLA-HIFRSBDPSA-N (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide Chemical compound C=1C=CC=CC=1[C@@]1(C(=O)N(CC)CC)C[C@@H]1CN GJJFMKBJSRMPLA-HIFRSBDPSA-N 0.000 claims 1
- YWPHCCPCQOJSGZ-LLVKDONJSA-N (2r)-2-[(2-ethoxyphenoxy)methyl]morpholine Chemical compound CCOC1=CC=CC=C1OC[C@@H]1OCCNC1 YWPHCCPCQOJSGZ-LLVKDONJSA-N 0.000 claims 1
- VMMYRRFPMAGXNP-BTYIYWSLSA-N 2-[4-[2-[[(1r,2s)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]-2,5-dimethylphenoxy]acetic acid Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC(C)=C(OCC(O)=O)C=C1C VMMYRRFPMAGXNP-BTYIYWSLSA-N 0.000 claims 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 239000000048 adrenergic agonist Substances 0.000 claims 1
- 229940126157 adrenergic receptor agonist Drugs 0.000 claims 1
- 229960002430 atomoxetine Drugs 0.000 claims 1
- VHGCDTVCOLNTBX-QGZVFWFLSA-N atomoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=CC=C1C VHGCDTVCOLNTBX-QGZVFWFLSA-N 0.000 claims 1
- 102000016959 beta-3 Adrenergic Receptors Human genes 0.000 claims 1
- 108010014502 beta-3 Adrenergic Receptors Proteins 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- MJRPHRMGEKCADU-JVLSTEMRSA-N lortalamine Chemical compound C12=CC(Cl)=CC=C2O[C@]23CCN(C)C[C@@H]2[C@H]1CC(=O)N3 MJRPHRMGEKCADU-JVLSTEMRSA-N 0.000 claims 1
- 229950004863 lortalamine Drugs 0.000 claims 1
- 229960000600 milnacipran Drugs 0.000 claims 1
- 229960001073 nomifensine Drugs 0.000 claims 1
- XXPANQJNYNUNES-UHFFFAOYSA-N nomifensine Chemical compound C12=CC=CC(N)=C2CN(C)CC1C1=CC=CC=C1 XXPANQJNYNUNES-UHFFFAOYSA-N 0.000 claims 1
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 claims 1
- 229940127221 norepinephrine reuptake inhibitor Drugs 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- AMJPIGOYWBNJLP-UHFFFAOYSA-N pirandamine Chemical compound C1C2=CC=CC=C2C2=C1C(CCN(C)C)(C)OCC2 AMJPIGOYWBNJLP-UHFFFAOYSA-N 0.000 claims 1
- 229950007239 pirandamine Drugs 0.000 claims 1
- DTPOQEUUHFQKSS-UHFFFAOYSA-N pyrrolo[2,1,5-cd]indolizine Chemical compound C1=CC(N23)=CC=C3C=CC2=C1 DTPOQEUUHFQKSS-UHFFFAOYSA-N 0.000 claims 1
- 229960003770 reboxetine Drugs 0.000 claims 1
- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 claims 1
- 229940076279 serotonin Drugs 0.000 claims 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 claims 1
- LJBBMCNHIUJBDU-UHFFFAOYSA-N talopram Chemical compound O1C(C)(C)C2=CC=CC=C2C1(CCCNC)C1=CC=CC=C1 LJBBMCNHIUJBDU-UHFFFAOYSA-N 0.000 claims 1
- 229950007352 talopram Drugs 0.000 claims 1
- BRPOADLGOFPKKJ-UHFFFAOYSA-N tandamine Chemical compound C12=CC=CC=C2N(CC)C2=C1CCSC2(C)CCN(C)C BRPOADLGOFPKKJ-UHFFFAOYSA-N 0.000 claims 1
- 229950006964 tandamine Drugs 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 229960004688 venlafaxine Drugs 0.000 claims 1
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 claims 1
- 229960001255 viloxazine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02026546A EP1424079A1 (en) | 2002-11-27 | 2002-11-27 | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| PCT/EP2003/012225 WO2004047830A2 (de) | 2002-11-27 | 2003-11-03 | Pharmazeutische zusammensetzung aus einem beta-3-adrenozeptor-agonisten und einem serotonin- und/oder norepinephrin-reuptake-inhibitor deren verwendung zur behandlung von blasenfunktionsstörungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006509751A JP2006509751A (ja) | 2006-03-23 |
| JP2006509751A5 true JP2006509751A5 (cg-RX-API-DMAC7.html) | 2006-12-21 |
Family
ID=32241298
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004554308A Pending JP2006509751A (ja) | 2002-11-27 | 2003-11-03 | β−３アドレナリン受容体アゴニストとセロトニン及び／又はノルエピネフリン再取り込み阻害剤とを含む医薬組成物 |
| JP2004554318A Pending JP2006509752A (ja) | 2002-11-27 | 2003-11-05 | β−３アドレナリン受容体アゴニスト及び抗ムスカリン作用薬を含む医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004554318A Pending JP2006509752A (ja) | 2002-11-27 | 2003-11-05 | β−３アドレナリン受容体アゴニスト及び抗ムスカリン作用薬を含む医薬組成物 |
Country Status (22)
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7704527B2 (en) * | 2002-10-25 | 2010-04-27 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| JP2007509896A (ja) * | 2003-11-03 | 2007-04-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | β−３−アドレノセプターアゴニスト及びαアンタゴニスト及び／又は５−αレダクターゼインヒビターを含有する医薬組成物 |
| DE10356112A1 (de) * | 2003-11-27 | 2005-06-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem in den Prostglandinstoffwechsel eingreifendem Wirkstoff |
| EP1804778A1 (de) * | 2004-10-18 | 2007-07-11 | Boehringer Ingelheim International GmbH | Verwendung eines beta-3-agonisten zur behandlung von beschwerden der prostata und des unteren urogenitaltrakts |
| US20090247781A1 (en) * | 2004-10-26 | 2009-10-01 | Kissei Pharmaceutical Co., Ltd. | Synthesis of phenoxyacetic acid derivatives |
| EP1852117A4 (en) * | 2005-02-25 | 2010-10-27 | Astellas Pharma Inc | PHARMACEUTICAL AGENT COMPRISING SOLIFENACIN |
| US20060165776A1 (en) * | 2005-08-31 | 2006-07-27 | Ramesh Sesha | Antidepressant oral pharmaceutical compositions |
| EP1769792A1 (de) * | 2005-09-30 | 2007-04-04 | Boehringer Ingelheim Pharma GmbH & Co.KG | Verwendung eines beta-3-Adrenozeptor-Agonisten zur Behandlung von Nieren- und Blasenbeschwerden |
| US9440003B2 (en) * | 2005-11-04 | 2016-09-13 | Boston Scientific Scimed, Inc. | Medical devices having particle-containing regions with diamond-like coatings |
| FR2895259B1 (fr) * | 2005-12-22 | 2008-02-22 | Urosphere Sas | Methodes de traitement des incontinences urinaires |
| WO2007080776A1 (ja) * | 2006-01-10 | 2007-07-19 | Kissei Pharmaceutical Co., Ltd. | 徐放性製剤およびその製造方法 |
| MX2008014758A (es) * | 2006-05-22 | 2009-01-19 | Teva Pharma | Formulaciones de liberacion retardada de clorhidrato de duloxetina. |
| US20090175935A1 (en) * | 2006-08-14 | 2009-07-09 | Torrent Research Ltd. | Pharmaceutical compositions of duloxetine |
| EP1947103A1 (en) | 2007-01-22 | 2008-07-23 | 4Sc Ag | Aryloxypropanolamines, methods of preparation thereof and use of aryloxypropanolamines as medicaments |
| US20080226711A1 (en) * | 2007-03-12 | 2008-09-18 | Torrent Pharmaceuticals Ltd. | Pharmaceutical compositions of duloxetine |
| WO2009066181A2 (en) * | 2007-07-09 | 2009-05-28 | Combino Pharm, S.L. | Oral delayed-release duloxentine hydrochloride pellets |
| ES2393525T3 (es) * | 2007-11-02 | 2012-12-26 | Astellas Pharma Inc. | Composición farmacéutica para el tratamiento de la vejiga hiperactiva |
| TWI478712B (zh) | 2008-09-30 | 2015-04-01 | Astellas Pharma Inc | 釋控性醫藥組成物 |
| ES2376095B1 (es) * | 2008-10-02 | 2013-01-24 | Laboratorios Del Dr. Esteve, S.A. | Pellets entéricos de duloxetina. |
| US20110262566A1 (en) * | 2008-11-07 | 2011-10-27 | Dainippon Sumitomo Pharma Co., Ltd. | Novel useful therapeutic agent for lower urinary tract symptom |
| EP2316432A1 (de) * | 2009-10-30 | 2011-05-04 | ratiopharm GmbH | Zusammensetzung enthaltend Fesoterodin und Ballaststoffe |
| EP2377525A1 (en) * | 2010-03-26 | 2011-10-19 | Laboratorios del Dr. Esteve S.A. | Duloxetine enteric pellets |
| JP5849947B2 (ja) | 2010-03-29 | 2016-02-03 | アステラス製薬株式会社 | 放出制御医薬組成物 |
| US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| AU2011285928B9 (en) * | 2010-08-03 | 2018-08-02 | B3Ar Therapeutics, Inc. | Combinations of beta - 3 adrenergic receptor agonists and muscarinic receptor antagonists for treating overactive bladder |
| SG11201404776PA (en) * | 2012-02-09 | 2014-09-26 | Altherx Inc | Combination of muscarinic receptor antagonists and beta- 3 adrenoceptor agonists for treating overactive bladder |
| KR102141433B1 (ko) * | 2012-09-18 | 2020-08-05 | 타리스 바이오메디컬 엘엘씨 | 트로스피움을 이용함으로써 방광 배뇨 장애 및 다른 하부 요도관 장애의 치료를 위한 약물 전달 시스템과 방법 |
| PL224543B1 (pl) | 2013-08-21 | 2017-01-31 | Pabianickie Zakłady Farm Polfa Spółka Akcyjna | Dojelitowa tabletka duloksetyny |
| CN107205964A (zh) | 2014-12-03 | 2017-09-26 | 威力塞帕特治疗股份有限公司 | 使用调节释放索拉贝隆用于下尿路症状的组合物和方法 |
| CA3000230A1 (en) * | 2015-10-15 | 2017-04-20 | Duke University | State-dependent peripheral neuromodulation to treat bladder dysfunction |
| PT3365321T (pt) | 2015-10-23 | 2024-01-12 | B3Ar Therapeutics Inc | Zwiterião de solabegron e suas utilizações |
| US20190307696A1 (en) | 2016-04-25 | 2019-10-10 | Synthon B.V. | Tablets comprising mirabegron and solifenacin |
| EP3448366A1 (en) | 2016-04-25 | 2019-03-06 | Synthon B.V. | Modified release tablet composition comprising mirabegron |
| US10478399B2 (en) | 2017-10-12 | 2019-11-19 | Synthon B.V. | Modified release tablet composition comprising mirabegron |
| US12097189B1 (en) | 2024-02-09 | 2024-09-24 | Astellas Pharma Inc. | Pharmaceutical composition for modified release |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956388A (en) * | 1986-12-22 | 1990-09-11 | Eli Lilly And Company | 3-aryloxy-3-substituted propanamines |
| ZA921292B (en) * | 1991-02-25 | 1993-08-23 | Lilly Co Eli | Treatment of lower urinary tract disorders. |
| IL104567A (en) * | 1992-02-03 | 1997-03-18 | Fujisawa Pharmaceutical Co | Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| US6262115B1 (en) * | 1995-05-22 | 2001-07-17 | Alza Coporation | Method for the management of incontinence |
| WO1997015549A1 (en) * | 1995-10-26 | 1997-05-01 | Tokyo Tanabe Company Limited | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS β3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME |
| ES2208772T3 (es) * | 1996-01-10 | 2004-06-16 | Asahi Kasei Kabushiki Kaisha | Nuevos compuestos triciclicos y compuestos farmaceuticos que contienen los mismos. |
| CZ287798A3 (cs) * | 1996-03-11 | 1999-05-12 | Eli Lilly And Company | Použití duloxetinu pro výrobu léčiva, duloxetin k použití v léčbě nebo prevenci a farmaceutický přípravek s jeho obsahem |
| CA2259012C (en) * | 1996-07-19 | 2008-05-13 | Gunnar Aberg | S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders |
| EP0958835A4 (en) * | 1996-08-19 | 2001-04-18 | Kissei Pharmaceutical | THERAPEUTIC OR PREVENTIVE REMEDY AGAINST INCONTINENCE OR FREQUENT URINARY ELIMINATION |
| TR199901063T2 (xx) * | 1996-11-14 | 1999-08-23 | Pfizer Inc. | �kame edilmi� piridinler i�in i�lem. |
| WO1998022480A1 (en) * | 1996-11-18 | 1998-05-28 | Smithkline Beecham Plc | Phosphorus containing aryloxy or arylthio propanolamine derivatives |
| JPH1112171A (ja) * | 1997-06-19 | 1999-01-19 | Nisshin Flour Milling Co Ltd | 消化器疾患治療薬 |
| ID24062A (id) * | 1997-07-25 | 2000-07-06 | Kissei Pharmaceutical | Turunan-turunan asam aminoetilfenoksiasetat dan obat untuk mengurangi nyeri dan membantu penyingkiran dalam litiasis saluran air kencing |
| BR9804500B1 (pt) * | 1997-10-17 | 2010-06-15 | derivado de amida, referida composição farmacêutica e agente terapêutico. | |
| IL136612A (en) * | 1997-12-18 | 2003-11-23 | Kissei Pharmaceutical | Phenylaminoalkyl-carboxylic acid derivatives and pharmaceutical compositions containing the same |
| US6319920B1 (en) * | 1998-02-27 | 2001-11-20 | Syntex (U.S.A.) Llc | 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives |
| JP2002512639A (ja) * | 1998-04-06 | 2002-04-23 | 藤沢薬品工業株式会社 | プロパノールアミン誘導体 |
| CA2328348C (en) * | 1998-04-14 | 2009-03-03 | Kissei Pharmaceutical Co., Ltd. | 2-methylpropionic acid derivatives and medicinal compositions containing the same |
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| MY126489A (en) * | 1998-07-08 | 2006-10-31 | Kissei Pharmaceutical | Phenoxyacetic acid derivatives and medicinal compositions containing the same |
| DE69942928D1 (de) * | 1998-08-27 | 2010-12-23 | Pfizer Health Ab | Therapeutische formulierung zur verabreichung von tolterodin mit kontrollierter freisetzung |
| DE19932651A1 (de) * | 1999-07-13 | 2001-01-18 | Hexal Ag | Transdermales therapeutisches System zur Anwendung von Tolterodin |
| DE60015036T2 (de) * | 1999-07-23 | 2006-03-02 | Pfizer Products Inc., Groton | Zwischenprodukte und ein Verfahren zur Herstellung von beta3-Adrenergischer Rezeptor-Agoniste |
| DK1227806T3 (da) * | 1999-11-11 | 2005-10-31 | Pfizer Health Ab | Farmaceutisk præparat indeholdende tolterodin og dets anvendelse |
| US6562368B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers |
| SE9904850D0 (sv) * | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| AU2710301A (en) * | 2000-01-28 | 2001-08-07 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
| PT1257277E (pt) * | 2000-02-24 | 2005-09-30 | Pharmacia & Upjohn Co Llc | Novas combinacoes de farmacos |
| AU5596600A (en) * | 2000-06-07 | 2001-12-17 | Bridge Pharma Inc | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
| US6514991B2 (en) * | 2000-07-17 | 2003-02-04 | Wyeth | Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists |
| AU2002232470B2 (en) * | 2001-01-02 | 2005-11-03 | Pharmacia & Upjohn Company Llc | New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents |
| GB0102408D0 (en) * | 2001-01-31 | 2001-03-14 | Glaxo Group Ltd | Chemical compounds |
| EP1236723A1 (en) * | 2001-03-01 | 2002-09-04 | Pfizer Products Inc. | Sulfamide derivatives useful as beta3 agonists and pharmaceutical uses thereof |
| US6696450B2 (en) * | 2001-04-04 | 2004-02-24 | Wyeth | Serotonergic agents with long-acting in vivo effects |
| WO2003035600A1 (en) * | 2001-10-19 | 2003-05-01 | Fujisawa Pharmaceutical Co., Ltd. | Process for producing benzocycloheptene derivative |
| JP2005511582A (ja) * | 2001-11-05 | 2005-04-28 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | 抗ムスカリン・エアゾール |
| CN1633283A (zh) * | 2002-02-19 | 2005-06-29 | 法玛西雅公司 | 环加氧酶抑制剂和抗蕈毒碱试剂用于治疗失禁的用途 |
-
2002
- 2002-11-27 EP EP02026546A patent/EP1424079A1/en not_active Withdrawn
-
2003
- 2003-03-11 UA UAA200506227A patent/UA81931C2/uk unknown
- 2003-11-03 HR HR20050467A patent/HRP20050467A2/xx not_active Application Discontinuation
- 2003-11-03 PL PL03376259A patent/PL376259A1/xx unknown
- 2003-11-03 MX MXPA05005483A patent/MXPA05005483A/es not_active Application Discontinuation
- 2003-11-03 WO PCT/EP2003/012225 patent/WO2004047830A2/de not_active Ceased
- 2003-11-03 RS RSP-2005/0392A patent/RS20050392A/sr unknown
- 2003-11-03 EP EP03778298A patent/EP1572181B1/de not_active Expired - Lifetime
- 2003-11-03 DE DE50310046T patent/DE50310046D1/de not_active Expired - Fee Related
- 2003-11-03 CA CA002507266A patent/CA2507266A1/en not_active Abandoned
- 2003-11-03 AT AT03778298T patent/ATE399005T1/de not_active IP Right Cessation
- 2003-11-03 KR KR1020057009414A patent/KR20050088295A/ko not_active Withdrawn
- 2003-11-03 BR BR0316535-3A patent/BR0316535A/pt not_active IP Right Cessation
- 2003-11-03 EA EA200500776A patent/EA009781B1/ru not_active IP Right Cessation
- 2003-11-03 CN CNA2003801044257A patent/CN1717230A/zh active Pending
- 2003-11-03 JP JP2004554308A patent/JP2006509751A/ja active Pending
- 2003-11-03 AU AU2003285312A patent/AU2003285312A1/en not_active Abandoned
- 2003-11-03 ES ES03778298T patent/ES2309371T3/es not_active Expired - Lifetime
- 2003-11-03 EP EP05027827A patent/EP1640000A3/de not_active Withdrawn
- 2003-11-05 JP JP2004554318A patent/JP2006509752A/ja active Pending
- 2003-11-05 WO PCT/EP2003/012331 patent/WO2004047838A2/de not_active Ceased
- 2003-11-05 EP EP03782183A patent/EP1567149A2/de not_active Withdrawn
- 2003-11-05 AU AU2003289854A patent/AU2003289854A1/en not_active Abandoned
- 2003-11-05 CA CA002507343A patent/CA2507343A1/en not_active Abandoned
-
2005
- 2005-04-22 ZA ZA200503282A patent/ZA200503282B/en unknown
- 2005-05-23 EC EC2005005814A patent/ECSP055814A/es unknown
- 2005-05-24 US US11/136,165 patent/US20090012161A9/en not_active Abandoned
- 2005-05-24 US US11/136,148 patent/US20050261328A1/en not_active Abandoned
- 2005-06-23 NO NO20053088A patent/NO20053088L/no not_active Application Discontinuation
- 2005-06-27 CO CO05062906A patent/CO5580754A2/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006509751A5 (cg-RX-API-DMAC7.html) | ||
| JP2006509752A5 (cg-RX-API-DMAC7.html) | ||
| CO5580754A2 (es) | Composicion farmaceutica a base de un agonista de receptor adrenergico beta-3 y un inhibidor de la reabsorcion de se- rotonina y/o norepinefrina | |
| JP5933176B2 (ja) | タペンタドールの用量調節 | |
| US10813890B2 (en) | Pharmaceutical combination | |
| CA2716080C (en) | Cns pharmaceutical compositions and methods of use | |
| JP2005512995A5 (cg-RX-API-DMAC7.html) | ||
| EP2167065A1 (en) | Combination therapy for depression | |
| JP2013523775A (ja) | 睡眠の質を改善するための方法 | |
| JP2023143940A5 (cg-RX-API-DMAC7.html) | ||
| TW201912153A (zh) | 用於治療ｂ型肝炎的化合物、醫藥組合物及方法 | |
| US20220062279A1 (en) | Treatment of movement disorders | |
| JP2024543419A (ja) | Ｓｓａｏ阻害剤による肝障害の治療 | |
| RU2008112176A (ru) | Профилактическое или терапевтическое средство для заболевания, вызванного уменьшением количества слезной жидкости | |
| CA2415154A1 (en) | Modified release formulations of selective serotonin re-uptake inhibitors | |
| CN105848655B (zh) | 用于注意力和认知障碍的、以及用于与神经变性障碍相关联的痴呆的新疗法 | |
| TWI409061B (zh) | 莫達非尼於縮短抗抑鬱劑效果的開始時間的用途 | |
| JP2008509147A5 (cg-RX-API-DMAC7.html) | ||
| JP2007502865A5 (cg-RX-API-DMAC7.html) | ||
| US20070123555A1 (en) | Prevention and treatment of hearing disorders | |
| RU2004122639A (ru) | Способ получения 1r,2s-метоксамина, его терапевтическое применение (варианты) и фармацевтическая композиция | |
| WO2020229388A1 (en) | Mirtazapine for use in medication overuse headache based on tension-type headache | |
| CN116194092A (zh) | 经口给予制剂 | |
| MX2013011079A (es) | Composiciones farmaceuticas para el tratamiento del dolor agudo y neuropatico con base en el enantiomero activo (+)- tramadol o sus sales. | |
| US20220323435A1 (en) | Composition and method for treatment of depression and psychosis in humans |