JP2006508134A - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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Publication number
JP2006508134A
JP2006508134A JP2004552010A JP2004552010A JP2006508134A JP 2006508134 A JP2006508134 A JP 2006508134A JP 2004552010 A JP2004552010 A JP 2004552010A JP 2004552010 A JP2004552010 A JP 2004552010A JP 2006508134 A JP2006508134 A JP 2006508134A
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
pharmaceutically acceptable
hydroxymethyl
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004552010A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006508134A5 (https=
Inventor
グッドソン，ゲーリー，ウェイン
フロイド，アリソン，グリーン
ナヴィー，セシリア，カーペンター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2006508134A publication Critical patent/JP2006508134A/ja
Publication of JP2006508134A5 publication Critical patent/JP2006508134A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP2004552010A 2002-11-08 2003-11-07 医薬組成物 Pending JP2006508134A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42518202P 2002-11-08 2002-11-08
PCT/US2003/035830 WO2004043433A2 (en) 2002-11-08 2003-11-07 Pharmaceutical antiviral compositions

Publications (2)

Publication Number Publication Date
JP2006508134A true JP2006508134A (ja) 2006-03-09
JP2006508134A5 JP2006508134A5 (https=) 2006-12-21

Family

ID=32312939

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004552010A Pending JP2006508134A (ja) 2002-11-08 2003-11-07 医薬組成物

Country Status (9)

Country Link
US (1) US20050287177A1 (https=)
EP (1) EP1567133B1 (https=)
JP (1) JP2006508134A (https=)
AT (1) ATE361059T1 (https=)
AU (1) AU2003291457A1 (https=)
CA (1) CA2505130C (https=)
DE (1) DE60313657T2 (https=)
ES (1) ES2286471T3 (https=)
WO (1) WO2004043433A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
ES2320663T3 (es) 2003-08-26 2009-05-27 Smithkline Beecham Corporation Nuevos indoles cicloalquil(b) condensados.
TW201414495A (zh) 2005-04-04 2014-04-16 Tibotec Pharm Ltd Ｈｉｖ-感染之預防
RU2008128424A (ru) * 2005-12-14 2010-01-20 Сипла Лимитед (In) Фармацевтическая комбинация, включающая нуклеотидный и нуклеозидный ингибиторы обратной транскриптазы (такие как тенофовир и ламивудин) в различных частях дозы
PT1981506E (pt) 2006-01-20 2013-06-25 Janssen R & D Ireland Tratamento a longo prazo da infeção pelo vih com tmc278
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
JP2010529073A (ja) * 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア チュアブル錠及びトローチ剤製造のための医薬製剤
MX2009013063A (es) * 2007-06-06 2010-01-15 Basf Se Formulacion farmaceutica para la produccion de tabletas de desintegracion rapida.
MX2009013499A (es) * 2007-06-22 2010-01-18 Bristol Myers Squibb Co Composiciones comprimidas que contienen atazanavir.
KR101057640B1 (ko) * 2009-05-27 2011-08-18 (주)다산메디켐 발포성 층을 포함하는 다층 정제

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63255230A (ja) * 1987-03-27 1988-10-21 ザ　ウエルカム　フアウンデーシヨン　リミテツド 徐放性製剤
US5681581A (en) * 1992-08-04 1997-10-28 Dunn; James M. Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use
JP2001502718A (ja) * 1996-10-31 2001-02-27 グラクソ、グループ、リミテッド ラミブジンおよびジドブジンを含む医薬組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) * 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
GB9009861D0 (en) * 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
WO1992020344A1 (en) * 1991-05-16 1992-11-26 Glaxo Group Limited Antiviral combinations containing nucleoside analogs
GB9111902D0 (en) * 1991-06-03 1991-07-24 Glaxo Group Ltd Chemical compounds
US6177435B1 (en) * 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63255230A (ja) * 1987-03-27 1988-10-21 ザ　ウエルカム　フアウンデーシヨン　リミテツド 徐放性製剤
US5681581A (en) * 1992-08-04 1997-10-28 Dunn; James M. Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use
JP2001502718A (ja) * 1996-10-31 2001-02-27 グラクソ、グループ、リミテッド ラミブジンおよびジドブジンを含む医薬組成物

Also Published As

Publication number Publication date
EP1567133B1 (en) 2007-05-02
DE60313657T2 (de) 2008-01-03
CA2505130A1 (en) 2004-05-27
ES2286471T3 (es) 2007-12-01
AU2003291457A8 (en) 2004-06-03
EP1567133A2 (en) 2005-08-31
AU2003291457A1 (en) 2004-06-03
ATE361059T1 (de) 2007-05-15
US20050287177A1 (en) 2005-12-29
DE60313657D1 (de) 2007-06-14
CA2505130C (en) 2009-10-06
WO2004043433A3 (en) 2004-12-29
WO2004043433A2 (en) 2004-05-27

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