JP2006117675A5 - - Google Patents

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Publication number
JP2006117675A5
JP2006117675A5 JP2005304883A JP2005304883A JP2006117675A5 JP 2006117675 A5 JP2006117675 A5 JP 2006117675A5 JP 2005304883 A JP2005304883 A JP 2005304883A JP 2005304883 A JP2005304883 A JP 2005304883A JP 2006117675 A5 JP2006117675 A5 JP 2006117675A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2005304883A
Other languages
Japanese (ja)
Other versions
JP2006117675A (ja
JP4101833B2 (ja
Filing date
Publication date
Priority claimed from US08/326,110 external-priority patent/US5945275A/en
Priority claimed from US08/486,397 external-priority patent/US5866542A/en
Priority claimed from US08/486,399 external-priority patent/US5866543A/en
Priority claimed from US08/465,380 external-priority patent/US5863894A/en
Priority claimed from US08/461,965 external-priority patent/US5872098A/en
Application filed filed Critical
Publication of JP2006117675A publication Critical patent/JP2006117675A/ja
Publication of JP2006117675A5 publication Critical patent/JP2006117675A5/ja
Application granted granted Critical
Publication of JP4101833B2 publication Critical patent/JP4101833B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2005304883A 1994-10-18 2005-10-19 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質 Expired - Fee Related JP4101833B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/326,110 US5945275A (en) 1994-10-18 1994-10-18 Nematode-extracted anticoagulant protein
US08/486,397 US5866542A (en) 1994-10-18 1995-06-05 Nematode-extracted anticoagulant protein
US08/486,399 US5866543A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US08/465,380 US5863894A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US08/461,965 US5872098A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP51339996A Division JP3811186B2 (ja) 1994-10-18 1995-10-17 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006356647A Division JP2007145851A (ja) 1994-10-18 2006-12-28 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質

Publications (3)

Publication Number Publication Date
JP2006117675A JP2006117675A (ja) 2006-05-11
JP2006117675A5 true JP2006117675A5 (enExample) 2006-08-31
JP4101833B2 JP4101833B2 (ja) 2008-06-18

Family

ID=27541063

Family Applications (3)

Application Number Title Priority Date Filing Date
JP51339996A Expired - Fee Related JP3811186B2 (ja) 1994-10-18 1995-10-17 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質
JP2005304883A Expired - Fee Related JP4101833B2 (ja) 1994-10-18 2005-10-19 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質
JP2006356647A Pending JP2007145851A (ja) 1994-10-18 2006-12-28 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP51339996A Expired - Fee Related JP3811186B2 (ja) 1994-10-18 1995-10-17 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006356647A Pending JP2007145851A (ja) 1994-10-18 2006-12-28 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質

Country Status (12)

Country Link
US (11) US6090916A (enExample)
EP (2) EP1772516A1 (enExample)
JP (3) JP3811186B2 (enExample)
AT (1) ATE346928T1 (enExample)
AU (1) AU711405B2 (enExample)
DE (1) DE69535317T2 (enExample)
DK (1) DK0788546T3 (enExample)
ES (1) ES2276396T3 (enExample)
HU (1) HU225126B1 (enExample)
NZ (1) NZ296648A (enExample)
PL (1) PL183855B1 (enExample)
WO (1) WO1996012021A2 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP1772516A1 (en) * 1994-10-18 2007-04-11 Dendreon Corporation Pharmaceutical compositions for the treatment of thrombosis
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
ES2232196T3 (es) * 1998-12-23 2005-05-16 The Horticulture And Food Research Institute Of New Zealand Limited Inhibidor de la serin proteasa.
US7074556B2 (en) * 1999-03-02 2006-07-11 Invitrogen Corporation cDNA synthesis improvements
US6849605B1 (en) 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
WO2000051623A2 (en) 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US7704958B1 (en) 1999-03-05 2010-04-27 Bio Holding, Inc. Methods and compositions for inhibiting apoptosis using serine protease inhibitors
DE60014919T2 (de) * 1999-08-06 2005-10-13 Genentech, Inc., South San Francisco Peptidantagonisten des faktors viia
WO2001036351A2 (en) 1999-11-19 2001-05-25 Corvas International, Inc. Plasminogen activator inhibitor antagonists related applications
US6703494B2 (en) * 2000-03-16 2004-03-09 Genentech, Inc. Anti-tissue factor antibodies with enhanced anticoagulant potency
US20040072315A1 (en) * 2001-02-05 2004-04-15 Xinjie Lu Integrin-binding chimeras
US20030143225A1 (en) * 2001-03-08 2003-07-31 Genentech, Inc. Combinations of anti-tissue factor antibodies and anticoagulant and/or antiplatelet agents
EP1569912B1 (en) 2002-12-03 2015-04-29 Pharmacyclics, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
US7164002B2 (en) 2002-02-06 2007-01-16 Genentech, Inc. FVIIa antagonists
US20040001801A1 (en) * 2002-05-23 2004-01-01 Corvas International, Inc. Conjugates activated by cell surface proteases and therapeutic uses thereof
ATE528014T1 (de) 2002-06-07 2011-10-15 Dyax Corp Polypeptid mit modifizierten kunitz domains
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US20040152072A1 (en) * 2002-07-30 2004-08-05 Invitrogen Corporation Reverse transcription
EP1542710B1 (en) * 2002-08-28 2012-09-26 Dyax Corp. Methods for preserving organs and tissues
CN100355783C (zh) * 2003-02-20 2007-12-19 刘凤鸣 一种抗凝蛋白及其编码基因与它的高效表达方法
US7132398B2 (en) * 2003-05-06 2006-11-07 Dendreon Corporation Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor
US20040229334A1 (en) * 2003-05-15 2004-11-18 Mendoza Christine B. Process for manufacture of nematode-extracted anticoagulant protein (NAP)
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7685191B1 (en) 2005-06-16 2010-03-23 Enquisite, Inc. Selection of advertisements to present on a web page or other destination based on search activities of users who selected the destination
KR100757354B1 (ko) 2006-03-07 2007-09-11 강릉대학교산학협력단 꼼치 알 유래의 단백분해효소 저해제의 분리방법
WO2007106746A2 (en) * 2006-03-10 2007-09-20 Dyax Corp. Formulations for ecallantide
US8889117B2 (en) * 2007-02-15 2014-11-18 Yale University Modular nanoparticles for adaptable vaccines
US20100015160A1 (en) * 2007-02-21 2010-01-21 Yale University Compositions and methods for diagnosing and treating endometriosis
CN102617722B (zh) * 2007-03-05 2013-10-16 广东医学院 犬钩虫抗凝肽及其制备和应用
US8105795B2 (en) * 2008-05-19 2012-01-31 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting roundworm
CA2724717C (en) 2008-05-19 2018-06-19 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting roundworm
JP2013516389A (ja) * 2009-01-06 2013-05-13 ダイアックス コーポレーション カリクレイン阻害剤による粘膜炎治療
KR101499302B1 (ko) 2009-11-17 2015-03-09 아이덱스 래보러토리즈, 인코포레이티드 회충을 검출하기 위한 방법, 장치, 키트 및 조성물
ES2905545T3 (es) 2010-01-06 2022-04-11 Takeda Pharmaceuticals Co Proteínas de unión a calicreína plasmática
IL269565B2 (en) 2011-01-06 2024-06-01 Dyax Corp Plasma kallikrein binding proteins
US9958160B2 (en) 2013-02-06 2018-05-01 United Technologies Corporation Gas turbine engine component with upstream-directed cooling film holes
EP2954261B1 (en) 2013-02-08 2020-03-04 United Technologies Corporation Gas turbine engine combustor
KR101374194B1 (ko) * 2013-05-16 2014-03-13 대한민국 대하로부터 분리한 쿠니츠형 세린 프로테아제 저해인자
EP3122782A4 (en) 2014-03-27 2017-09-13 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
CN116077648A (zh) 2015-12-11 2023-05-09 武田药品工业株式会社 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
WO2018175581A1 (en) 2017-03-21 2018-09-27 The Jackson Laboratory A GENETICALLY MODIFIED MOUSE EXPRESSING HUMAN APOE4 MOUSE Trem2.p.R47H AND METHODS OF USE THEREOF
JP2023526880A (ja) * 2020-05-26 2023-06-26 ウニヴェルシテーツメディツィン・デア・ヨハネス・グーテンベルク－ウニヴェルシテート・マインツ コロナウイルス感染症および関連する凝固障害を処置するための方法および組成物
AU2022291028A1 (en) * 2021-06-09 2024-01-18 Universitätsmedizin Der Johannes Gutenberg-Universität Mainz Methods and compositions for treatment of autoimmune conditions

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4745051A (en) * 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
US4808537A (en) * 1984-10-30 1989-02-28 Phillips Petroleum Company Methanol inducible genes obtained from pichia and methods of use
US4885242A (en) * 1984-10-30 1989-12-05 Phillips Petroleum Company Genes from pichia histidine pathway and uses thereof
US4879231A (en) * 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4837148A (en) * 1984-10-30 1989-06-06 Phillips Petroleum Company Autonomous replication sequences for yeast strains of the genus pichia
US5166329A (en) * 1985-10-25 1992-11-24 Phillips Petroleum Company DNA encoding the alcohol oxidase 2 gene of yeast of the genus Pichia
US4818700A (en) * 1985-10-25 1989-04-04 Phillips Petroleum Company Pichia pastoris argininosuccinate lyase gene and uses thereof
US4882279A (en) * 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US5135868A (en) * 1985-10-25 1992-08-04 Phillips Petroleum Company Cultures of yeast of the genus Pichia altered by site selective genomic modification
US5032516A (en) * 1985-10-25 1991-07-16 Phillips Petroleum Company Pichia pastoris alcohol oxidase II regulatory region
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
US4812405A (en) * 1986-02-18 1989-03-14 Phillips Petroleum Company Double auxotrophic mutants of Pichia pastoris and methods for preparation
US4857467A (en) * 1986-07-23 1989-08-15 Phillips Petroleum Company Carbon and energy source markers for transformation of strains of the genes Pichia
US5258288A (en) * 1986-07-25 1993-11-02 Genzyme Corporation Vector containing DNA encoding mature human protein S
US5002876A (en) * 1986-09-22 1991-03-26 Phillips Petroleum Company Yeast production of human tumor necrosis factor
US4777242A (en) * 1986-10-10 1988-10-11 Phillips Petroleum Company Purification of recombinant tumor necrosis factor
US4683293A (en) * 1986-10-20 1987-07-28 Phillips Petroleum Company Purification of pichia produced lipophilic proteins
DK299087D0 (da) * 1987-06-12 1987-06-12 Novo Industri As Proteins and derivatives thereof
US5106833A (en) * 1987-07-23 1992-04-21 Washington University Coagulation inhibitors
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
JPH0219399A (ja) * 1988-07-05 1990-01-23 Oklahoma Medical Res Found トロンビン結合ポリピペプチド
JPH02255699A (ja) * 1989-03-28 1990-10-16 Asahi Chem Ind Co Ltd 新規血液抗凝固物質及びその製法
US5122465A (en) * 1989-06-12 1992-06-16 Phillips Petroleum Company Strains of pichia pastoris created by interlocus recombination
JPH0637711B2 (ja) * 1989-06-22 1994-05-18 新日本製鐵株式会社 黒色表面処理鋼板の製造方法
WO1991001383A1 (en) * 1989-07-14 1991-02-07 Michigan State University Method for diagnosing blood clotting disorders
CA2022713A1 (en) * 1989-08-11 1991-02-12 Nils U. Bang Human thrombomodulin derivatives
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
CA2024697A1 (en) * 1989-09-07 1991-03-08 George P. Vlasuk Protein having anticoagulant properties
US5239058A (en) * 1989-09-07 1993-08-24 Merck & Co., Inc. Proteins having anticoagulant properties
EP0439442B1 (en) * 1990-01-25 1996-03-06 Washington University Factor x-laci hybrid protein
US5189019A (en) * 1990-04-23 1993-02-23 Merck & Co., Inc. Antistasin derived anticoagulant protein
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
US5204261A (en) * 1991-04-24 1993-04-20 Phillips Petroleum Company Catalase-negative pichia pastoris
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5239059A (en) * 1991-05-10 1993-08-24 The Children's Hospital Of Philadelphia Ion-channel forming peptides
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US5427937A (en) * 1993-04-30 1995-06-27 Cappello; Michael Hookworm anticoagulant
GB9322576D0 (en) * 1993-11-02 1993-12-22 Univ Nottingham Antihaemostatic agents
US5589359A (en) * 1994-08-05 1996-12-31 Chiron Corporation Chimeric proteins
DE69528591T2 (de) * 1994-08-05 2003-02-20 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Herstellung des inhibitors fuer die komplexbildung des gewebefaktors
EP1772516A1 (en) * 1994-10-18 2007-04-11 Dendreon Corporation Pharmaceutical compositions for the treatment of thrombosis
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US7132398B2 (en) * 2003-05-06 2006-11-07 Dendreon Corporation Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor

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