JP2005527575A - 糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与 - Google Patents
糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与 Download PDFInfo
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- JP2005527575A JP2005527575A JP2003581774A JP2003581774A JP2005527575A JP 2005527575 A JP2005527575 A JP 2005527575A JP 2003581774 A JP2003581774 A JP 2003581774A JP 2003581774 A JP2003581774 A JP 2003581774A JP 2005527575 A JP2005527575 A JP 2005527575A
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- diabetic foot
- substituted
- foot lesion
- infection according
- treating diabetic
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36910402P | 2002-03-29 | 2002-03-29 | |
| PCT/US2003/008882 WO2003084534A1 (en) | 2002-03-29 | 2003-03-21 | Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005527575A true JP2005527575A (ja) | 2005-09-15 |
| JP2005527575A5 JP2005527575A5 (enExample) | 2006-05-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003581774A Withdrawn JP2005527575A (ja) | 2002-03-29 | 2003-03-21 | 糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20030216330A1 (enExample) |
| EP (1) | EP1490059A1 (enExample) |
| JP (1) | JP2005527575A (enExample) |
| KR (1) | KR20040095328A (enExample) |
| CN (1) | CN1642543A (enExample) |
| AU (1) | AU2003223334A1 (enExample) |
| BR (1) | BR0308806A (enExample) |
| CA (1) | CA2476545A1 (enExample) |
| IL (1) | IL164195A0 (enExample) |
| MX (1) | MXPA04009356A (enExample) |
| NO (1) | NO20044672L (enExample) |
| NZ (1) | NZ535648A (enExample) |
| PL (1) | PL372661A1 (enExample) |
| RU (1) | RU2354372C2 (enExample) |
| WO (1) | WO2003084534A1 (enExample) |
| ZA (1) | ZA200407734B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012520864A (ja) * | 2009-03-16 | 2012-09-10 | アストラゼネカ アクチボラグ | 結核の治療のための化合物 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200404069A (en) * | 2002-06-28 | 2004-03-16 | Upjohn Co | Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent |
| JP4579502B2 (ja) * | 2003-05-02 | 2010-11-10 | キヤノン株式会社 | 構造体及びその製造方法、該構造体を含むトナー並びにそれを用いた画像形成方法及び装置 |
| PT1656370E (pt) | 2003-06-03 | 2012-11-29 | Rib X Pharmaceuticals Inc | Compostos biaril-heterocíclicos e métodos de os produzir e de os utilizar |
| US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
| AR046782A1 (es) * | 2003-12-17 | 2005-12-21 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos. |
| WO2006008640A1 (en) * | 2004-07-15 | 2006-01-26 | Pharmacia & Upjohn Company Llc | Non-aqueous suspension containing a drug having an unpleasant taste |
| TW200612923A (en) * | 2004-07-29 | 2006-05-01 | Ferrer Int | Oxazolidinone compounds and compositions and methods related thereto |
| KR101394307B1 (ko) | 2005-06-08 | 2014-05-13 | 멜린타 테라퓨틱스, 인크. | 트리아졸의 합성 방법 |
| EP1745784A1 (en) * | 2005-06-27 | 2007-01-24 | Ferrer Internacional, S.A. | Oxazolidinone derivatives and use thereof as antibiotics |
| WO2007000644A1 (en) | 2005-06-29 | 2007-01-04 | Pharmacia & Upjohn Company Llc | Homomorpholine oxazolidinones as antibacterial agents |
| US9427468B2 (en) * | 2007-08-22 | 2016-08-30 | Trustees Of Dartmouth College | Compositions and methods for diagnosing and treating community-acquired methicillin-resistant Staphylococcus aureus |
| WO2012082992A1 (en) * | 2010-12-15 | 2012-06-21 | Biovista, Inc. | Compositions and methods for cancer treatment |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5043443A (en) * | 1988-07-29 | 1991-08-27 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives |
| US5225565A (en) * | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| US5182403A (en) * | 1988-09-15 | 1993-01-26 | The Upjohn Company | Substituted 3(5'indazolyl) oxazolidin-2-ones |
| US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
| EP0610265B1 (en) * | 1991-11-01 | 1996-12-27 | PHARMACIA & UPJOHN COMPANY | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| CZ288788B6 (cs) * | 1992-12-08 | 2001-09-12 | Pharmacia & Upjohn Company | Antibakteriální fenyloxazolidinony substituované troponem |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| EP0730591B1 (en) * | 1993-11-22 | 1999-07-14 | PHARMACIA & UPJOHN COMPANY | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| DE4425609A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
| DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
| KR100392216B1 (ko) * | 1994-11-15 | 2003-10-17 | 파마시아 앤드 업존 캄파니 | 이환상옥사진및티아진옥사졸리디논항세균물질 |
| HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| SK283487B6 (sk) * | 1995-09-01 | 2003-08-05 | Pharmacia And Upjohn Company | Fenyloxazolidinóny majúce C-C väzbu v 4 až 8 členných heterocyklických kruhoch |
| DE19601264A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| CN1288462A (zh) * | 1998-01-23 | 2001-03-21 | 法玛西雅厄普约翰美国公司 | 噁唑烷酮组合库、组合物和制备方法 |
| MY122454A (en) * | 1998-06-05 | 2006-04-29 | Upjohn Co | Use of oxazolidinones for the preparation of a medicament for transdermal delivery |
| JP2004501965A (ja) * | 2000-06-30 | 2004-01-22 | ファルマシア・アンド・アップジョン・カンパニー | 細菌感染を治療するための組成物および方法 |
-
2003
- 2003-03-21 PL PL03372661A patent/PL372661A1/xx not_active Application Discontinuation
- 2003-03-21 MX MXPA04009356A patent/MXPA04009356A/es not_active Application Discontinuation
- 2003-03-21 EP EP03719451A patent/EP1490059A1/en not_active Withdrawn
- 2003-03-21 WO PCT/US2003/008882 patent/WO2003084534A1/en not_active Ceased
- 2003-03-21 AU AU2003223334A patent/AU2003223334A1/en not_active Abandoned
- 2003-03-21 IL IL16419503A patent/IL164195A0/xx unknown
- 2003-03-21 CA CA002476545A patent/CA2476545A1/en not_active Abandoned
- 2003-03-21 RU RU2004131830/14A patent/RU2354372C2/ru not_active IP Right Cessation
- 2003-03-21 CN CNA038073471A patent/CN1642543A/zh active Pending
- 2003-03-21 US US10/394,912 patent/US20030216330A1/en not_active Abandoned
- 2003-03-21 BR BR0308806-5A patent/BR0308806A/pt not_active IP Right Cessation
- 2003-03-21 JP JP2003581774A patent/JP2005527575A/ja not_active Withdrawn
- 2003-03-21 KR KR10-2004-7015307A patent/KR20040095328A/ko not_active Ceased
- 2003-03-21 NZ NZ535648A patent/NZ535648A/en unknown
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2004
- 2004-09-23 ZA ZA200407734A patent/ZA200407734B/en unknown
- 2004-10-28 NO NO20044672A patent/NO20044672L/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012520864A (ja) * | 2009-03-16 | 2012-09-10 | アストラゼネカ アクチボラグ | 結核の治療のための化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003084534A1 (en) | 2003-10-16 |
| CA2476545A1 (en) | 2003-10-16 |
| EP1490059A1 (en) | 2004-12-29 |
| IL164195A0 (en) | 2005-12-18 |
| RU2004131830A (ru) | 2005-04-10 |
| ZA200407734B (en) | 2005-06-24 |
| KR20040095328A (ko) | 2004-11-12 |
| NZ535648A (en) | 2007-05-31 |
| MXPA04009356A (es) | 2005-01-25 |
| US20030216330A1 (en) | 2003-11-20 |
| BR0308806A (pt) | 2005-01-04 |
| NO20044672L (no) | 2004-12-23 |
| PL372661A1 (en) | 2005-07-25 |
| AU2003223334A1 (en) | 2003-10-20 |
| CN1642543A (zh) | 2005-07-20 |
| RU2354372C2 (ru) | 2009-05-10 |
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