ZA200407734B - Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections. - Google Patents
Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections. Download PDFInfo
- Publication number
- ZA200407734B ZA200407734B ZA200407734A ZA200407734A ZA200407734B ZA 200407734 B ZA200407734 B ZA 200407734B ZA 200407734 A ZA200407734 A ZA 200407734A ZA 200407734 A ZA200407734 A ZA 200407734A ZA 200407734 B ZA200407734 B ZA 200407734B
- Authority
- ZA
- South Africa
- Prior art keywords
- composition
- substance
- substituted
- treatment according
- oxazolidinone
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
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| US36910402P | 2002-03-29 | 2002-03-29 |
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| EP (1) | EP1490059A1 (enExample) |
| JP (1) | JP2005527575A (enExample) |
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| CN (1) | CN1642543A (enExample) |
| AU (1) | AU2003223334A1 (enExample) |
| BR (1) | BR0308806A (enExample) |
| CA (1) | CA2476545A1 (enExample) |
| IL (1) | IL164195A0 (enExample) |
| MX (1) | MXPA04009356A (enExample) |
| NO (1) | NO20044672L (enExample) |
| NZ (1) | NZ535648A (enExample) |
| PL (1) | PL372661A1 (enExample) |
| RU (1) | RU2354372C2 (enExample) |
| WO (1) | WO2003084534A1 (enExample) |
| ZA (1) | ZA200407734B (enExample) |
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| TW200404069A (en) * | 2002-06-28 | 2004-03-16 | Upjohn Co | Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent |
| JP4579502B2 (ja) * | 2003-05-02 | 2010-11-10 | キヤノン株式会社 | 構造体及びその製造方法、該構造体を含むトナー並びにそれを用いた画像形成方法及び装置 |
| US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
| AU2004267007C1 (en) | 2003-06-03 | 2010-04-29 | Melinta Subsidiary Corp. | Biaryl heterocyclic compounds and methods of making and using the same |
| US7129259B2 (en) | 2003-12-17 | 2006-10-31 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
| WO2006008640A1 (en) * | 2004-07-15 | 2006-01-26 | Pharmacia & Upjohn Company Llc | Non-aqueous suspension containing a drug having an unpleasant taste |
| TW200612923A (en) * | 2004-07-29 | 2006-05-01 | Ferrer Int | Oxazolidinone compounds and compositions and methods related thereto |
| DE602006019870D1 (de) | 2005-06-08 | 2011-03-10 | Rib X Pharmaceuticals Inc | Verfahren zur synthese von triazolen |
| EP1745784A1 (en) * | 2005-06-27 | 2007-01-24 | Ferrer Internacional, S.A. | Oxazolidinone derivatives and use thereof as antibiotics |
| JP2008544979A (ja) | 2005-06-29 | 2008-12-11 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 抗菌剤としてのホモモルホリンオキサゾリジノン |
| WO2009032470A2 (en) * | 2007-08-22 | 2009-03-12 | Trustees Of Dartmouth College | Compositions and methods for diagnosing and treating community-acquired methicillin-resistant staphylococcus aureus |
| TW201036609A (en) * | 2009-03-16 | 2010-10-16 | Astrazeneca Ab | Compound for the treatment of tuberculosis |
| US9795601B2 (en) * | 2010-12-15 | 2017-10-24 | Biovista, Inc. | Compositions and methods for cancer treatment |
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| US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
| US5043443A (en) * | 1988-07-29 | 1991-08-27 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5225565A (en) * | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| US5182403A (en) * | 1988-09-15 | 1993-01-26 | The Upjohn Company | Substituted 3(5'indazolyl) oxazolidin-2-ones |
| US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
| CA2119556C (en) * | 1991-11-01 | 2004-07-06 | Michael Robert Barbachyn | Substituted aryl- and heteroaryl-phenyloxazolidinones |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| HUT74099A (en) * | 1992-12-08 | 1996-11-28 | Upjohn Co | Tropone-substituted phenyloxazolidinone antibacterial agents and pharmaceutical compositions containing the same |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| EP0730591B1 (en) * | 1993-11-22 | 1999-07-14 | PHARMACIA & UPJOHN COMPANY | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE4425609A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
| DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
| PT792273E (pt) * | 1994-11-15 | 2003-06-30 | Upjohn Co | Produtos antibacterianos de oxazolidinona substituida com oxazina e tiazina biciclicas |
| HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| FI980452A7 (fi) * | 1995-09-01 | 1998-02-27 | Upjohn Co | Fenyylioksatsolidinoneja, jotka ovat liittyneet C-C-sidoksella 4-8-jäs enisiin heterosyklisiin renkaisiin |
| DE19601264A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| US6239152B1 (en) * | 1998-01-23 | 2001-05-29 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| MY122454A (en) * | 1998-06-05 | 2006-04-29 | Upjohn Co | Use of oxazolidinones for the preparation of a medicament for transdermal delivery |
| ATE301474T1 (de) * | 2000-06-30 | 2005-08-15 | Pharmacia & Upjohn Co Llc | Zusammensetzungen zur behandlung baktrieller infektionen, welche ein oxazolidinonderivat, sulbactam und ampicillin enthalten |
-
2003
- 2003-03-21 IL IL16419503A patent/IL164195A0/xx unknown
- 2003-03-21 WO PCT/US2003/008882 patent/WO2003084534A1/en not_active Ceased
- 2003-03-21 NZ NZ535648A patent/NZ535648A/en unknown
- 2003-03-21 KR KR10-2004-7015307A patent/KR20040095328A/ko not_active Ceased
- 2003-03-21 CA CA002476545A patent/CA2476545A1/en not_active Abandoned
- 2003-03-21 AU AU2003223334A patent/AU2003223334A1/en not_active Abandoned
- 2003-03-21 RU RU2004131830/14A patent/RU2354372C2/ru not_active IP Right Cessation
- 2003-03-21 CN CNA038073471A patent/CN1642543A/zh active Pending
- 2003-03-21 PL PL03372661A patent/PL372661A1/xx not_active Application Discontinuation
- 2003-03-21 US US10/394,912 patent/US20030216330A1/en not_active Abandoned
- 2003-03-21 JP JP2003581774A patent/JP2005527575A/ja not_active Withdrawn
- 2003-03-21 BR BR0308806-5A patent/BR0308806A/pt not_active IP Right Cessation
- 2003-03-21 MX MXPA04009356A patent/MXPA04009356A/es not_active Application Discontinuation
- 2003-03-21 EP EP03719451A patent/EP1490059A1/en not_active Withdrawn
-
2004
- 2004-09-23 ZA ZA200407734A patent/ZA200407734B/en unknown
- 2004-10-28 NO NO20044672A patent/NO20044672L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04009356A (es) | 2005-01-25 |
| IL164195A0 (en) | 2005-12-18 |
| US20030216330A1 (en) | 2003-11-20 |
| RU2354372C2 (ru) | 2009-05-10 |
| WO2003084534A1 (en) | 2003-10-16 |
| CA2476545A1 (en) | 2003-10-16 |
| EP1490059A1 (en) | 2004-12-29 |
| KR20040095328A (ko) | 2004-11-12 |
| CN1642543A (zh) | 2005-07-20 |
| BR0308806A (pt) | 2005-01-04 |
| AU2003223334A1 (en) | 2003-10-20 |
| PL372661A1 (en) | 2005-07-25 |
| JP2005527575A (ja) | 2005-09-15 |
| RU2004131830A (ru) | 2005-04-10 |
| NO20044672L (no) | 2004-12-23 |
| NZ535648A (en) | 2007-05-31 |
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