JP2005526058A - グリコゲンホスホリラーゼの阻害剤としての複素環式アミド誘導体 - Google Patents

グリコゲンホスホリラーゼの阻害剤としての複素環式アミド誘導体 Download PDF

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Publication number
JP2005526058A
JP2005526058A JP2003573000A JP2003573000A JP2005526058A JP 2005526058 A JP2005526058 A JP 2005526058A JP 2003573000 A JP2003573000 A JP 2003573000A JP 2003573000 A JP2003573000 A JP 2003573000A JP 2005526058 A JP2005526058 A JP 2005526058A
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Japan
Prior art keywords
oxo
thieno
pyrrole
alkyl
chloro
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Withdrawn
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JP2003573000A
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Japanese (ja)
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JP2005526058A5 (enExample
Inventor
バーチ，アラン・マーティン
モーリー，アンドリュー・デービッド
ストッカー，アンドリュー
ホウィッタモア，ポール・ロバート・オーウェン
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AstraZeneca AB
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AstraZeneca AB
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Publication of JP2005526058A publication Critical patent/JP2005526058A/ja
Publication of JP2005526058A5 publication Critical patent/JP2005526058A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2003573000A 2002-03-06 2003-03-04 グリコゲンホスホリラーゼの阻害剤としての複素環式アミド誘導体 Withdrawn JP2005526058A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0205165.4A GB0205165D0 (en) 2002-03-06 2002-03-06 Chemical compounds
PCT/GB2003/000877 WO2003074532A1 (en) 2002-03-06 2003-03-04 Heterocyclic amide derivatives as inhibitors of glycogen phosphorylase

Publications (2)

Publication Number Publication Date
JP2005526058A true JP2005526058A (ja) 2005-09-02
JP2005526058A5 JP2005526058A5 (enExample) 2006-04-06

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ID=9932329

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Application Number Title Priority Date Filing Date
JP2003573000A Withdrawn JP2005526058A (ja) 2002-03-06 2003-03-04 グリコゲンホスホリラーゼの阻害剤としての複素環式アミド誘導体

Country Status (18)

Country Link
US (2) US7129249B2 (enExample)
EP (1) EP1483270A1 (enExample)
JP (1) JP2005526058A (enExample)
KR (1) KR20040096661A (enExample)
CN (1) CN100384852C (enExample)
AR (1) AR038888A1 (enExample)
AU (1) AU2003214377A1 (enExample)
BR (1) BR0308146A (enExample)
CA (1) CA2477667A1 (enExample)
GB (1) GB0205165D0 (enExample)
IL (1) IL163803A0 (enExample)
MX (1) MXPA04008614A (enExample)
NO (1) NO20043852L (enExample)
NZ (1) NZ534990A (enExample)
PL (1) PL372973A1 (enExample)
TW (1) TW200305412A (enExample)
WO (1) WO2003074532A1 (enExample)
ZA (1) ZA200406679B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018039784A (ja) * 2009-10-16 2018-03-15 メリンタ セラピューティクス，インコーポレイテッド 抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
US10259825B2 (en) 2009-10-16 2019-04-16 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
US10947237B2 (en) 2015-03-11 2021-03-16 BioVersys AG Antimicrobial compounds and methods of making and using the same
US11999739B2 (en) 2016-05-06 2024-06-04 BioVersys AG Antimicrobials methods of making and using the same

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US7402674B2 (en) 2004-01-31 2008-07-22 Sanofi-Aventis Deutschland Gmbh, 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
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JP5438975B2 (ja) 2006-01-06 2014-03-12 サノビオン ファーマシューティカルズ インク テトラロン系モノアミン再取り込み阻害剤
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CN112442022B (zh) * 2019-09-02 2022-05-20 承德医学院 苯并嗪-4-酮类化合物、其制备方法及医药用途
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018039784A (ja) * 2009-10-16 2018-03-15 メリンタ セラピューティクス，インコーポレイテッド 抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
US10259825B2 (en) 2009-10-16 2019-04-16 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
US10947237B2 (en) 2015-03-11 2021-03-16 BioVersys AG Antimicrobial compounds and methods of making and using the same
US11999739B2 (en) 2016-05-06 2024-06-04 BioVersys AG Antimicrobials methods of making and using the same

Also Published As

Publication number Publication date
PL372973A1 (en) 2005-08-08
BR0308146A (pt) 2004-12-07
GB0205165D0 (en) 2002-04-17
CN100384852C (zh) 2008-04-30
CN1653070A (zh) 2005-08-10
US7129249B2 (en) 2006-10-31
US7276517B2 (en) 2007-10-02
KR20040096661A (ko) 2004-11-16
AR038888A1 (es) 2005-02-02
TW200305412A (en) 2003-11-01
NZ534990A (en) 2006-02-24
AU2003214377A1 (en) 2003-09-16
CA2477667A1 (en) 2003-09-12
MXPA04008614A (es) 2004-12-06
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NO20043852L (no) 2004-09-14
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US20070043069A1 (en) 2007-02-22
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