JP2005523928A5 - - Google Patents

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Publication number
JP2005523928A5
JP2005523928A5 JP2004500769A JP2004500769A JP2005523928A5 JP 2005523928 A5 JP2005523928 A5 JP 2005523928A5 JP 2004500769 A JP2004500769 A JP 2004500769A JP 2004500769 A JP2004500769 A JP 2004500769A JP 2005523928 A5 JP2005523928 A5 JP 2005523928A5
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JP
Japan
Prior art keywords
composition
glaucoma
ctgf
intraocular pressure
patient
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JP2004500769A
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English (en)
Japanese (ja)
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JP2005523928A (ja
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Priority claimed from PCT/US2003/012521 external-priority patent/WO2003092584A2/en
Publication of JP2005523928A publication Critical patent/JP2005523928A/ja
Publication of JP2005523928A5 publication Critical patent/JP2005523928A5/ja
Withdrawn legal-status Critical Current

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JP2004500769A 2002-04-30 2003-04-18 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤 Withdrawn JP2005523928A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37660602P 2002-04-30 2002-04-30
PCT/US2003/012521 WO2003092584A2 (en) 2002-04-30 2003-04-18 Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2006035819A Division JP2006131643A (ja) 2002-04-30 2006-02-13 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤
JP2010208643A Division JP2010280723A (ja) 2002-04-30 2010-09-16 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤

Publications (2)

Publication Number Publication Date
JP2005523928A JP2005523928A (ja) 2005-08-11
JP2005523928A5 true JP2005523928A5 (enExample) 2006-03-23

Family

ID=29401375

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004500769A Withdrawn JP2005523928A (ja) 2002-04-30 2003-04-18 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤
JP2006035819A Pending JP2006131643A (ja) 2002-04-30 2006-02-13 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤
JP2010208643A Withdrawn JP2010280723A (ja) 2002-04-30 2010-09-16 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2006035819A Pending JP2006131643A (ja) 2002-04-30 2006-02-13 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤
JP2010208643A Withdrawn JP2010280723A (ja) 2002-04-30 2010-09-16 眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤

Country Status (15)

Country Link
US (3) US7351407B2 (enExample)
EP (2) EP1497420A4 (enExample)
JP (3) JP2005523928A (enExample)
KR (1) KR20040104566A (enExample)
CN (1) CN1650001A (enExample)
AR (1) AR039511A1 (enExample)
AU (2) AU2003221762B2 (enExample)
BR (1) BR0309623A (enExample)
CA (1) CA2482789A1 (enExample)
MX (1) MXPA04009471A (enExample)
PL (1) PL378030A1 (enExample)
RU (1) RU2332213C2 (enExample)
TW (1) TWI288640B (enExample)
WO (1) WO2003092584A2 (enExample)
ZA (1) ZA200408021B (enExample)

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ATE400297T1 (de) 2004-02-11 2008-07-15 Fibrogen Inc Ctgf als zielmolekül in der behandlung von mikroalbuminurie in patienten mit diabetischer nephropathie
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US20060275797A1 (en) * 2005-03-21 2006-12-07 Alcon Manufacturing, Ltd. Use of agents which inhibit connective tissue growth factor (CTGF) binding and signaling via the TrkA/p75NTR receptor complex for the prevention and treatment of CTGF-mediated ocular disorders
EP2002841A4 (en) 2006-03-23 2009-04-15 Senju Pharma Co OPHTHALMIC COMPOSITION WITH XANTHANGUMMI AND GLUCOSE
CN101505744A (zh) * 2006-07-25 2009-08-12 爱尔康研究有限公司 用于预防和治疗眼部病症的内皮分化基因亚家庭3(edg-3,s1p3)受体的拮抗剂
US20080057072A1 (en) * 2006-08-31 2008-03-06 Alcon Manufacturing, Ltd. Antagonists of ci-m6p/igf2r for prevention and treatment of ctgf-mediated ocular disorders
US20090202524A1 (en) * 2007-10-31 2009-08-13 Alcon Research, Ltd. Pai-1 expression and activity inhibitors for the treatment of ocular disorders
US20100158897A1 (en) * 2006-10-31 2010-06-24 Alcon Research, Ltd. Pai-1 modulators for the treatment of ocular disorders
AU2007313684A1 (en) * 2006-10-31 2008-05-08 Alcon Research, Ltd. PAI-1 binding modulators for the treatment of ocular disorders
US7807629B1 (en) 2007-06-05 2010-10-05 Alcon Research, Ltd. Use of bradykinin and related B2R agonists to treat ocular hypertension and glaucoma
US8173668B1 (en) 2007-06-05 2012-05-08 Alcon Research, Ltd. Use of non-peptidic bradykinin receptor agonists to treat ocular hypertension and glaucoma
RU2392960C1 (ru) * 2008-09-26 2010-06-27 Учреждение Российской академии медицинских наук Научный центр реконструктивной и восстановительной хирургии Сибирского отделения РАМН (НЦРВХ СО РАМН) Способ коррекции плотности соединительной ткани
RU2411033C1 (ru) * 2009-05-12 2011-02-10 Государственное образовательное учреждение высшего профессионального образования "Владивостокский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ВГМУ Росздрава) Способ лечения глаукомной оптической нейропатии в пожилом и старом возрасте
CN102666587A (zh) 2009-07-02 2012-09-12 菲布罗根有限公司 用于治疗肌营养不良的方法
WO2011056234A1 (en) 2009-11-06 2011-05-12 Fibrogen, Inc. Treatment for radiation-induced disorders
EA025415B1 (ru) 2010-01-11 2016-12-30 Инотек Фармасьютикалз Корпорейшн Комбинация, набор и способ снижения внутриглазного давления
EP2569325A4 (en) 2010-03-26 2013-10-09 Inotek Pharmaceuticals Corp METHOD FOR REDUCING INNER EYE PRESSURE IN HUMANS USING N6-CYCLOPENTYLADENOSINE (CPA), CPA DERIVATIVES OR PRODRUGS THEREOF
RU2424796C1 (ru) * 2010-05-12 2011-07-27 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" Способ лечения токсической оптической нейропатии, вызванной длительным приемом кодеинсодержащих лекарственных средств
TW201210584A (en) 2010-08-18 2012-03-16 Alcon Res Ltd Bradykinin receptor agonists and uses thereof to treat ocular hypertension and glaucoma
US20140134181A1 (en) 2010-11-05 2014-05-15 Kenneth E. Lipson Treatment Method For Lung Remodeling Diseases
US9278991B2 (en) 2012-01-26 2016-03-08 Inotek Pharmaceuticals Corporation Anhydrous polymorphs of [(2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof
IN2015DN02699A (enExample) 2012-09-05 2015-09-04 Sylentis Sau
CA2903114A1 (en) 2013-03-15 2014-09-25 Inotek Pharmaceuticals Corporation Ophthalmic formulations
WO2015132303A1 (en) 2014-03-04 2015-09-11 Sylentis Sau Sirnas and their use in methods and compositions for the treatment and/or prevention of eye conditions
US11299537B2 (en) 2015-12-10 2022-04-12 Fibrogen, Inc. Methods for treatment of motor neuron diseases
DE102018107621A1 (de) * 2018-03-29 2019-10-02 Imedos Systems GmbH Vorrichtung und Verfahren zur Untersuchung der metabolischen Autoregulation
KR20190115725A (ko) 2018-04-03 2019-10-14 한국과학기술연구원 찰콘 유도체를 포함하는 시신경 보호용 조성물
US20200369759A1 (en) 2019-05-23 2020-11-26 Fibrogen, Inc. Methods of treatment of muscular dystrophies
KR102231354B1 (ko) 2020-05-22 2021-03-24 한국과학기술연구원 찰콘 유도체를 포함하는 시신경 보호용 조성물
IL300724A (en) * 2020-08-21 2023-04-01 Oculotherapy Llc Methods of neuroprotection and its uses

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