KR20040104566A - 안압 저하 및 녹내장성 망막병증/시신경병증 치료를 위한특유의 수단으로서의 결합 조직 성장 인자 (ｃｔｇｆ)의활성 및/또는 발현 조절, 저해, 또는 변조제 - Google Patents
안압 저하 및 녹내장성 망막병증/시신경병증 치료를 위한특유의 수단으로서의 결합 조직 성장 인자 (ｃｔｇｆ)의활성 및/또는 발현 조절, 저해, 또는 변조제 Download PDFInfo
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- KR20040104566A KR20040104566A KR10-2004-7016310A KR20047016310A KR20040104566A KR 20040104566 A KR20040104566 A KR 20040104566A KR 20047016310 A KR20047016310 A KR 20047016310A KR 20040104566 A KR20040104566 A KR 20040104566A
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| PCT/US2003/012521 WO2003092584A2 (en) | 2002-04-30 | 2003-04-18 | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190115725A (ko) | 2018-04-03 | 2019-10-14 | 한국과학기술연구원 | 찰콘 유도체를 포함하는 시신경 보호용 조성물 |
| KR20200062112A (ko) | 2020-05-22 | 2020-06-03 | 한국과학기술연구원 | 찰콘 유도체를 포함하는 시신경 보호용 조성물 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20040104566A (ko) * | 2002-04-30 | 2004-12-10 | 알콘, 인코퍼레이티드 | 안압 저하 및 녹내장성 망막병증/시신경병증 치료를 위한특유의 수단으로서의 결합 조직 성장 인자 (ｃｔｇｆ)의활성 및/또는 발현 조절, 저해, 또는 변조제 |
| TW200526224A (en) * | 2003-12-22 | 2005-08-16 | Alcon Inc | Short form c-Maf transcription factor antagonists for treatment of glaucoma |
| ATE400297T1 (de) | 2004-02-11 | 2008-07-15 | Fibrogen Inc | Ctgf als zielmolekül in der behandlung von mikroalbuminurie in patienten mit diabetischer nephropathie |
| AU2005244154C1 (en) | 2004-04-28 | 2010-07-01 | Fibrogen, Inc. | Treatments for pancreatic cancer |
| WO2006021817A2 (en) | 2004-08-23 | 2006-03-02 | Sylentis S.A.U. | Treatment of eye disorders characterized by an elevated introacular pressure by sirnas |
| US7803824B2 (en) * | 2004-10-29 | 2010-09-28 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases to treat glaucoma |
| TWI386225B (zh) * | 2004-12-23 | 2013-02-21 | Alcon Inc | 用於治療眼睛病症的結締組織生長因子（ＣＴＧＦ）ＲＮＡ干擾（ＲＮＡｉ）抑制技術 |
| US20060275797A1 (en) * | 2005-03-21 | 2006-12-07 | Alcon Manufacturing, Ltd. | Use of agents which inhibit connective tissue growth factor (CTGF) binding and signaling via the TrkA/p75NTR receptor complex for the prevention and treatment of CTGF-mediated ocular disorders |
| EP2002841A4 (en) | 2006-03-23 | 2009-04-15 | Senju Pharma Co | OPHTHALMIC COMPOSITION WITH XANTHANGUMMI AND GLUCOSE |
| CN101505744A (zh) * | 2006-07-25 | 2009-08-12 | 爱尔康研究有限公司 | 用于预防和治疗眼部病症的内皮分化基因亚家庭3（edg-3，s1p3）受体的拮抗剂 |
| US20080057072A1 (en) * | 2006-08-31 | 2008-03-06 | Alcon Manufacturing, Ltd. | Antagonists of ci-m6p/igf2r for prevention and treatment of ctgf-mediated ocular disorders |
| US20090202524A1 (en) * | 2007-10-31 | 2009-08-13 | Alcon Research, Ltd. | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
| US20100158897A1 (en) * | 2006-10-31 | 2010-06-24 | Alcon Research, Ltd. | Pai-1 modulators for the treatment of ocular disorders |
| AU2007313684A1 (en) * | 2006-10-31 | 2008-05-08 | Alcon Research, Ltd. | PAI-1 binding modulators for the treatment of ocular disorders |
| US7807629B1 (en) | 2007-06-05 | 2010-10-05 | Alcon Research, Ltd. | Use of bradykinin and related B2R agonists to treat ocular hypertension and glaucoma |
| US8173668B1 (en) | 2007-06-05 | 2012-05-08 | Alcon Research, Ltd. | Use of non-peptidic bradykinin receptor agonists to treat ocular hypertension and glaucoma |
| RU2392960C1 (ru) * | 2008-09-26 | 2010-06-27 | Учреждение Российской академии медицинских наук Научный центр реконструктивной и восстановительной хирургии Сибирского отделения РАМН (НЦРВХ СО РАМН) | Способ коррекции плотности соединительной ткани |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190115725A (ko) | 2018-04-03 | 2019-10-14 | 한국과학기술연구원 | 찰콘 유도체를 포함하는 시신경 보호용 조성물 |
| KR20200062112A (ko) | 2020-05-22 | 2020-06-03 | 한국과학기술연구원 | 찰콘 유도체를 포함하는 시신경 보호용 조성물 |
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| JP2010280723A (ja) | 2010-12-16 |
| CA2482789A1 (en) | 2003-11-13 |
| EP2221054A1 (en) | 2010-08-25 |
| WO2003092584A2 (en) | 2003-11-13 |
| RU2004134733A (ru) | 2005-05-10 |
| AU2008264214B2 (en) | 2011-03-31 |
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| JP2005523928A (ja) | 2005-08-11 |
| AU2003221762A1 (en) | 2003-11-17 |
| CN1650001A (zh) | 2005-08-03 |
| JP2006131643A (ja) | 2006-05-25 |
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