JP2005523843A - 生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法 - Google Patents

生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法 Download PDF

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JP2005523843A
JP2005523843A JP2003539439A JP2003539439A JP2005523843A JP 2005523843 A JP2005523843 A JP 2005523843A JP 2003539439 A JP2003539439 A JP 2003539439A JP 2003539439 A JP2003539439 A JP 2003539439A JP 2005523843 A JP2005523843 A JP 2005523843A
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container
frame
flexible container
biopharmaceutical material
temperature control
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Pending
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Japanese (ja)
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JP2005523843A5 (https=
Inventor
ヴォート,ニコラ
ロック,マキシム,エヌ.
ブラウン,デビッド,シー.
ケンドール,ジェームズ,ダブリュー.
ゲイセルハート,エドワード
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インテグレイテッド バイオシステムズ,インコーポレイテッド
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Publication of JP2005523843A publication Critical patent/JP2005523843A/ja
Publication of JP2005523843A5 publication Critical patent/JP2005523843A5/ja
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D31/00Other cooling or freezing apparatus
    • F25D31/001Plate freezers
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • A01N1/144Apparatus for temperature control, e.g. refrigerators or freeze-drying apparatus
    • A01N1/145Stationary or portable vessels generating cryogenic temperatures, e.g. liquid nitrogen baths
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/146Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/80Freezing; Subsequent thawing; Cooling
    • A23B2/805Materials not being transported through or in the apparatus with or without shaping, e.g. in the form of powders, granules or flakes
    • A23B2/8055Materials not being transported through or in the apparatus with or without shaping, e.g. in the form of powders, granules or flakes with packages or with shaping in the form of blocks or portions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/80Freezing; Subsequent thawing; Cooling
    • A23B2/82Thawing subsequent to freezing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0272Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • A61M1/0277Frames constraining or supporting bags, e.g. during freezing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0281Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00Charging, supporting, and discharging the articles to be cooled
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25BREFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2600/00Control issues
    • F25B2600/07Remote controls
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2331/00Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
    • F25D2331/80Type of cooled receptacles
    • F25D2331/801Bags
    • F25D2331/8014Bags for medical use
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2400/00General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
    • F25D2400/20Carts specially adapted for transporting objects to be cooled
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2400/00General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
    • F25D2400/30Quick freezing
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2500/00Problems to be solved
    • F25D2500/02Geometry problems

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Combustion & Propulsion (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Environmental Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
JP2003539439A 2001-11-01 2002-11-01 生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法 Pending JP2005523843A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33462201P 2001-11-01 2001-11-01
PCT/US2002/035135 WO2003037082A1 (en) 2001-11-01 2002-11-01 Systems and methods for freezing, storing and thawing biopharmaceutical material

Publications (2)

Publication Number Publication Date
JP2005523843A true JP2005523843A (ja) 2005-08-11
JP2005523843A5 JP2005523843A5 (https=) 2006-01-05

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Family Applications (2)

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JP2003539439A Pending JP2005523843A (ja) 2001-11-01 2002-11-01 生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法
JP2003539440A Pending JP2005507692A (ja) 2001-11-01 2002-11-01 生物薬剤材料を凍結及び貯蔵するためのシステム、及びその方法

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JP2003539440A Pending JP2005507692A (ja) 2001-11-01 2002-11-01 生物薬剤材料を凍結及び貯蔵するためのシステム、及びその方法

Country Status (9)

Country Link
EP (2) EP1441585B1 (https=)
JP (2) JP2005523843A (https=)
CN (3) CN1242670C (https=)
AT (2) ATE330466T1 (https=)
CA (2) CA2466122A1 (https=)
DE (2) DE60211731T2 (https=)
DK (2) DK1441586T3 (https=)
ES (2) ES2265057T3 (https=)
WO (2) WO2003037082A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009518242A (ja) * 2005-12-02 2009-05-07 スミスクライン・ビーチャム・コーポレイション バイオ医薬品製剤の凍結貯蔵容器
JP2012515688A (ja) * 2009-01-20 2012-07-12 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 低温容器
JP2015519929A (ja) * 2012-04-23 2015-07-16 フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 溶接された曲げ剛性プラスチック部分を有するバッグ
JP2018048787A (ja) * 2016-09-23 2018-03-29 大陽日酸株式会社 液体用バッグの急速凍結方法および急速凍結装置
JP2018111506A (ja) * 2017-01-11 2018-07-19 藤森工業株式会社 注出口付き包装袋
KR20210029710A (ko) * 2018-04-11 2021-03-16 바이오라이프 솔루션 인코포레이티드 냉동보관 백 (cryostorage bag) 보호를 위한 시스템들 및 방법들
JP2023070964A (ja) * 2021-11-10 2023-05-22 大陽日酸株式会社 予備凍結用ラック及び予備凍結方法

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WO2004055456A1 (en) * 2002-12-13 2004-07-01 Integrated Biosystems, Inc. Scaled down freezing and thawing system for bioparmaceuticals and biologics
DE102004015090A1 (de) 2004-03-25 2005-11-03 Hüttinger Elektronik Gmbh + Co. Kg Bogenentladungserkennungseinrichtung
JP4939405B2 (ja) 2005-04-28 2012-05-23 株式会社大塚製薬工場 薬液容器収容体およびその製造方法
WO2007023907A1 (ja) * 2005-08-24 2007-03-01 Transcu Ltd. 冷凍型イオントフォレーシス用電極構造体
WO2007103917A2 (en) * 2006-03-06 2007-09-13 Integrated Biosystems, Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
DK2080501T3 (en) 2006-10-27 2015-08-03 Otsuka Pharma Co Ltd Package containing drug solution with reduced dissolved oxygen content
CN101932235B (zh) * 2007-12-21 2014-06-18 赛多利斯斯泰迪北美有限公司 用于冷冻、贮存和解冻生物制药材料的系统和方法
US9301520B2 (en) 2007-12-21 2016-04-05 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
US8177123B2 (en) * 2008-09-24 2012-05-15 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
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US8371132B2 (en) * 2009-11-23 2013-02-12 Sartorius Stedim North America Inc. Systems and methods for use in freezing, thawing, and storing biopharmaceutical materials
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FR3003644B1 (fr) 2013-03-22 2015-03-20 Sartorius Stedim North America Inc Controle de l'etat de congelation d'un fluide biopharmaceutique se trouvant dans un conteneur.
FR3003550B1 (fr) 2013-03-22 2016-05-06 Sartorius Stedim North America Inc Installation et procede pour la preparation d'un conteneur charge avec un fluide biopharmaceutique.
CN103392691B (zh) * 2013-08-14 2015-09-23 北京瑞健高科生物科技有限公司 一种生物组织处理、灭菌及保存的容器和方法
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CA2957526C (en) 2014-08-08 2023-03-28 Fremon Scientific, Inc. Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
EP3199023B1 (en) 2016-01-27 2021-01-20 Sartorius Stedim North America Inc. Method and system for freezing biopharmaceutical fluid
US11304874B2 (en) * 2016-11-04 2022-04-19 Sartorius Stedim North America, Inc. Protecting body for a flexible pouch, system for containing a biopharmaceutical fluid and methods for using such a system
US20180324900A1 (en) 2017-05-04 2018-11-08 Fremon Scientific, Inc. Dry Heat Thawing of Biological Substances
CN108353890B (zh) * 2018-02-13 2021-01-26 京东方科技集团股份有限公司 一种生物片材固定装置
CN108357763B (zh) 2018-02-13 2019-07-16 京东方科技集团股份有限公司 一种生物片材存储装置
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CN111503959A (zh) * 2020-04-27 2020-08-07 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻工艺处理的冻融机
CN111503997B (zh) * 2020-04-27 2022-02-08 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻或混合工艺处理的冻融系统
CN111503978A (zh) * 2020-04-27 2020-08-07 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻工艺的装置
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US11571359B2 (en) 2020-07-30 2023-02-07 Sartorius Stedim North America Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
EP3960640A1 (en) 2020-08-28 2022-03-02 Sartorius Stedim Biotech GmbH Safety device for a single-use mixing or storage system
US12239127B2 (en) 2021-07-28 2025-03-04 Sartorius Stedim North America Inc. Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
CN114471754A (zh) * 2021-12-27 2022-05-13 利穗科技(苏州)有限公司 一种用于生物材料水溶液的容器

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009518242A (ja) * 2005-12-02 2009-05-07 スミスクライン・ビーチャム・コーポレイション バイオ医薬品製剤の凍結貯蔵容器
JP2012515688A (ja) * 2009-01-20 2012-07-12 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 低温容器
JP2015519929A (ja) * 2012-04-23 2015-07-16 フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 溶接された曲げ剛性プラスチック部分を有するバッグ
JP2018048787A (ja) * 2016-09-23 2018-03-29 大陽日酸株式会社 液体用バッグの急速凍結方法および急速凍結装置
JP2018111506A (ja) * 2017-01-11 2018-07-19 藤森工業株式会社 注出口付き包装袋
KR20210029710A (ko) * 2018-04-11 2021-03-16 바이오라이프 솔루션 인코포레이티드 냉동보관 백 (cryostorage bag) 보호를 위한 시스템들 및 방법들
KR102732698B1 (ko) 2018-04-11 2024-11-20 바이오라이프 솔루션 인코포레이티드 냉동보관 백 (cryostorage bag) 보호를 위한 시스템들 및 방법들
JP2023070964A (ja) * 2021-11-10 2023-05-22 大陽日酸株式会社 予備凍結用ラック及び予備凍結方法
JP7649231B2 (ja) 2021-11-10 2025-03-19 大陽日酸株式会社 予備凍結用ラック及び予備凍結方法

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Publication number Publication date
CN1229018C (zh) 2005-11-30
ATE330466T1 (de) 2006-07-15
CA2466130A1 (en) 2003-05-08
WO2003037082A1 (en) 2003-05-08
CN1315374C (zh) 2007-05-16
CN1582112A (zh) 2005-02-16
DE60211731T2 (de) 2007-05-16
WO2003037082A9 (en) 2004-01-15
ATE326841T1 (de) 2006-06-15
EP1441586A1 (en) 2004-08-04
JP2005507692A (ja) 2005-03-24
CN1732776A (zh) 2006-02-15
CA2466122A1 (en) 2003-05-08
CN1582111A (zh) 2005-02-16
HK1087889A1 (en) 2006-10-27
EP1441585B1 (en) 2006-05-24
EP1441585A1 (en) 2004-08-04
CN1242670C (zh) 2006-02-22
DE60212680T2 (de) 2007-06-28
WO2003037083A9 (en) 2004-01-15
DE60212680D1 (de) 2006-08-03
HK1074749A1 (en) 2005-11-25
DK1441585T3 (da) 2006-10-02
ES2265057T3 (es) 2007-02-01
DE60211731D1 (de) 2006-06-29
WO2003037083A1 (en) 2003-05-08
DK1441586T3 (da) 2006-10-23
EP1441586B1 (en) 2006-06-21
HK1074748A1 (en) 2005-11-25
ES2266588T3 (es) 2007-03-01

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