DE60211731D1 - Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material - Google Patents

Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material

Info

Publication number
DE60211731D1
DE60211731D1 DE60211731T DE60211731T DE60211731D1 DE 60211731 D1 DE60211731 D1 DE 60211731D1 DE 60211731 T DE60211731 T DE 60211731T DE 60211731 T DE60211731 T DE 60211731T DE 60211731 D1 DE60211731 D1 DE 60211731D1
Authority
DE
Germany
Prior art keywords
container
control unit
temperature control
flexible
freezing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60211731T
Other languages
English (en)
Other versions
DE60211731T2 (de
Inventor
Nicolas Voute
N Lok
C Brown
W Kendall
Edward Geiselhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim North America Inc
Original Assignee
Integrated Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integrated Biosystems Inc filed Critical Integrated Biosystems Inc
Publication of DE60211731D1 publication Critical patent/DE60211731D1/de
Application granted granted Critical
Publication of DE60211731T2 publication Critical patent/DE60211731T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D31/00—Other cooling or freezing apparatus
    • F25D31/001—Plate freezers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
    • A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/36—Freezing; Subsequent thawing; Cooling
    • A23L3/363—Freezing; Subsequent thawing; Cooling the materials not being transported through or in the apparatus with or without shaping, e.g. in form of powder, granules, or flakes
    • A23L3/364—Freezing; Subsequent thawing; Cooling the materials not being transported through or in the apparatus with or without shaping, e.g. in form of powder, granules, or flakes with packages or with shaping in form of blocks or portions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/36—Freezing; Subsequent thawing; Cooling
    • A23L3/365—Thawing subsequent to freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • A61M1/0277—Frames constraining or supporting bags, e.g. during freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00—Charging, supporting, and discharging the articles to be cooled
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2600/00—Control issues
    • F25B2600/07—Remote controls
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
    • F25D2331/80—Type of cooled receptacles
    • F25D2331/801—Bags
    • F25D2331/8014—Bags for medical use
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
    • F25D2400/20—Carts specially adapted for transporting objects to be cooled
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
    • F25D2400/30—Quick freezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2500/00—Problems to be solved
    • F25D2500/02—Geometry problems

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Thermal Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Wood Science & Technology (AREA)
  • Combustion & Propulsion (AREA)
  • Vascular Medicine (AREA)
  • Environmental Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Packages (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
DE60211731T 2001-11-01 2002-11-01 Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material Expired - Lifetime DE60211731T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33462201P 2001-11-01 2001-11-01
US334622P 2001-11-01
PCT/US2002/035135 WO2003037082A1 (en) 2001-11-01 2002-11-01 Systems and methods for freezing, storing and thawing biopharmaceutical material

Publications (2)

Publication Number Publication Date
DE60211731D1 true DE60211731D1 (de) 2006-06-29
DE60211731T2 DE60211731T2 (de) 2007-05-16

Family

ID=23308033

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60212680T Expired - Lifetime DE60212680T2 (de) 2001-11-01 2002-11-01 Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material
DE60211731T Expired - Lifetime DE60211731T2 (de) 2001-11-01 2002-11-01 Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60212680T Expired - Lifetime DE60212680T2 (de) 2001-11-01 2002-11-01 Vorrichtung und verfahren zum einfrieren und zur lagerung von biopharmazeutischem material

Country Status (10)

Country Link
EP (2) EP1441585B1 (de)
JP (2) JP2005507692A (de)
CN (3) CN1229018C (de)
AT (2) ATE330466T1 (de)
CA (2) CA2466130A1 (de)
DE (2) DE60212680T2 (de)
DK (2) DK1441585T3 (de)
ES (2) ES2266588T3 (de)
HK (3) HK1074748A1 (de)
WO (2) WO2003037082A1 (de)

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ATE416116T1 (de) * 2002-09-23 2008-12-15 Sartorius Stedim Systems Inc Verfahren und vorrichtung zum einfrieren, lagern, befördern und auftauen von biopharmazeutischem material
CA2509037A1 (en) * 2002-12-13 2004-07-01 Integrated Biosystems, Inc. Scaled down freezing and thawing system for bioparmaceuticals and biologics
DE102004015090A1 (de) 2004-03-25 2005-11-03 Hüttinger Elektronik Gmbh + Co. Kg Bogenentladungserkennungseinrichtung
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EP1957918A4 (de) * 2005-12-02 2012-03-21 Glaxosmithkline Llc Gefrier- und lagerungsbehälter für biopharmazeutische arzneimittelprodukte
EP2012585B1 (de) * 2006-03-06 2016-11-02 Sartorius Stedim North America Inc. Systeme und verfahren zum einfrieren, lagern und auftauen biopharmauzeutischer materialien
AU2007309987B2 (en) * 2006-10-27 2012-10-11 Otsuka Pharmaceutical Factory, Inc. Drug solution having reduced dissolved oxygen content, method of producing the same and drug solution containing unit having reduced dissolved oxygen content
CN101932235B (zh) * 2007-12-21 2014-06-18 赛多利斯斯泰迪北美有限公司 用于冷冻、贮存和解冻生物制药材料的系统和方法
US9301520B2 (en) 2007-12-21 2016-04-05 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
US8177123B2 (en) * 2008-09-24 2012-05-15 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
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US8371132B2 (en) * 2009-11-23 2013-02-12 Sartorius Stedim North America Inc. Systems and methods for use in freezing, thawing, and storing biopharmaceutical materials
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CN102322725B (zh) * 2011-09-13 2013-06-12 东莞市品翔饮水设备有限公司 制冰、制冷、制热直饮机
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US9441893B2 (en) * 2012-07-25 2016-09-13 Grifols, S.A. Thawing vessel for biological products
KR102074024B1 (ko) * 2012-10-31 2020-02-05 플루리스템 리미티드 생물학적 물질을 해동하기 위한 방법 및 장치
FR3003550B1 (fr) 2013-03-22 2016-05-06 Sartorius Stedim North America Inc Installation et procede pour la preparation d'un conteneur charge avec un fluide biopharmaceutique.
FR3003644B1 (fr) 2013-03-22 2015-03-20 Sartorius Stedim North America Inc Controle de l'etat de congelation d'un fluide biopharmaceutique se trouvant dans un conteneur.
CN103392691B (zh) * 2013-08-14 2015-09-23 北京瑞健高科生物科技有限公司 一种生物组织处理、灭菌及保存的容器和方法
PT107427B (pt) * 2014-01-28 2021-01-04 Inst Superior Tecnico Sistema e método de preservação, armazenamento e transporte de materiais biológicos.
CA2957526C (en) 2014-08-08 2023-03-28 Fremon Scientific, Inc. Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
EP3199023B1 (de) 2016-01-27 2021-01-20 Sartorius Stedim North America Inc. Verfahren und system zum einfrieren biopharmazeutischer flüssigkeiten
JP6696870B2 (ja) * 2016-09-23 2020-05-20 大陽日酸株式会社 液体用バッグの急速凍結方法および急速凍結装置
US11304874B2 (en) * 2016-11-04 2022-04-19 Sartorius Stedim North America, Inc. Protecting body for a flexible pouch, system for containing a biopharmaceutical fluid and methods for using such a system
JP6872369B2 (ja) * 2017-01-11 2021-05-19 藤森工業株式会社 注出口付き包装袋
CN108353890B (zh) * 2018-02-13 2021-01-26 京东方科技集团股份有限公司 一种生物片材固定装置
CN108357763B (zh) 2018-02-13 2019-07-16 京东方科技集团股份有限公司 一种生物片材存储装置
EP3772934A1 (de) * 2018-03-29 2021-02-17 W. L. Gore & Associates, Inc. Träger für aufbewahrungsbeutel zum einfrieren, lagern, transportieren und auftauen biologischer produkte
CN112512603A (zh) 2018-05-07 2021-03-16 弗莱蒙科学公司 解冻生物物质
NL2023121B1 (en) * 2019-05-13 2020-12-01 Nutritious Juices & Soups B V Food product dispensing system
CN111503959A (zh) * 2020-04-27 2020-08-07 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻工艺处理的冻融机
CN111503997B (zh) * 2020-04-27 2022-02-08 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻或混合工艺处理的冻融系统
CN111503978A (zh) * 2020-04-27 2020-08-07 上海东富龙科技股份有限公司 一种用于生物制药材料冷冻、解冻工艺的装置
US11590056B2 (en) 2020-07-30 2023-02-28 Sartorius Stedim North America Freeze/thaw containment system for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
US11590055B2 (en) 2020-07-30 2023-02-28 Sartorius Stedim North America Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
US11571359B2 (en) 2020-07-30 2023-02-07 Sartorius Stedim North America Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
EP3960640A1 (de) * 2020-08-28 2022-03-02 Sartorius Stedim Biotech GmbH Sicherheitsvorrichtung für ein misch- oder aufbewahrungssystem zur einmaligen verwendung
CN114471754A (zh) * 2021-12-27 2022-05-13 利穗科技(苏州)有限公司 一种用于生物材料水溶液的容器

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Also Published As

Publication number Publication date
HK1087889A1 (en) 2006-10-27
WO2003037083A9 (en) 2004-01-15
JP2005523843A (ja) 2005-08-11
WO2003037082A9 (en) 2004-01-15
ATE326841T1 (de) 2006-06-15
DK1441585T3 (da) 2006-10-02
DK1441586T3 (da) 2006-10-23
EP1441585A1 (de) 2004-08-04
ES2265057T3 (es) 2007-02-01
EP1441585B1 (de) 2006-05-24
ES2266588T3 (es) 2007-03-01
WO2003037082A1 (en) 2003-05-08
WO2003037083A1 (en) 2003-05-08
CN1242670C (zh) 2006-02-22
DE60212680D1 (de) 2006-08-03
CA2466130A1 (en) 2003-05-08
DE60211731T2 (de) 2007-05-16
CA2466122A1 (en) 2003-05-08
CN1229018C (zh) 2005-11-30
JP2005507692A (ja) 2005-03-24
CN1315374C (zh) 2007-05-16
CN1582112A (zh) 2005-02-16
EP1441586B1 (de) 2006-06-21
CN1582111A (zh) 2005-02-16
CN1732776A (zh) 2006-02-15
EP1441586A1 (de) 2004-08-04
DE60212680T2 (de) 2007-06-28
HK1074749A1 (en) 2005-11-25
ATE330466T1 (de) 2006-07-15
HK1074748A1 (en) 2005-11-25

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