JP2005517488A - 脂肪組織の超音波処理および画像化 - Google Patents
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Abstract
Description
本出願は、2002年2月20日に出願された、米国出願連続番号60/357,628(代理人整理番号021356−000100)の非仮出願であり、この全体の開示が、本明細書中において参考として援用される。
(1.発明の分野)本発明は、細胞を超音波的に破壊することによって、ヒト脂肪を切除するための方法および装置に関する。
従って、本発明は、関連技術の制限および欠点に起因する1つ以上の問題を実質的に取り除く様式で脂肪組織の超音波処理およびイメージングに関する。
データの電気的記憶のため、および複数のシステムコンポーネントを制御するためのコントローラー;
上記ヒト内に脂肪組織を存在させるための三次元座標位置データを確立するためのヒト身体をマッピングする手段であって、ここで、上記コントローラーは、ヒト身体上の複数の脂肪組織位置を識別し得、そして脂肪組織破壊のためのプロトコールを確立する;
高強度集束超音波を発するための1つ以上の圧電要素、および少なくとも1つのセンサーを有するトランスデューサーアセンブリであって、ここで、このセンサーは、上記コントローラーに上記1つ以上の圧電要素の安全作動のためのフィードバック情報を提供する;
ここで、上記少なくとも1つのセンサーは、上記コントローラーに電気的に接続され、そしてコントローラーは、上記三次元座標位置データから得られた位置情報に基づき、上記1つ以上の圧電要素に、必須の処置命令情報を提供する。
上記のように、美容および基礎的健康理由の両方のために、皮下脂肪組織の特定部分(または特定の主要部分)を取り除くことが有利である。この目的のために、本発明の原理によれば、患者との相談に際し、開業医は処置プランをセットアップする。この処置プランは、脂肪が身体内から除去されるべき領域中の脂肪の厚みを決定することを含む。次いで、脂肪の除去のための最適位置が自動的に決定される。一般に、身体内で最も深いレベルに位置する脂肪が最初に除去される。
ΣiAisin(ωτ+θi)=Bsin(ωτ+θ)
ここで、B2=(ΣiAicosθi)2+(ΣiAisinθi)2
そして、θ=tan−1((ΣiAisinθI)/(ΣiAicosθI))。
θi=tan−1(si/ci)
そして、Ai 2=ci 2+si 2。
Claims (46)
- 高強度集束超音波トランスデューサーであって、以下:
沸騰センサ;
空洞化センサ;および
該沸騰センサおよび空洞化センサに接続された、複数のトランスデューサー要素、
を備える、高強度集束超音波トランスデューサー。 - 前記複数のトランスデューサー要素の各々によって放射されるエネルギー量が、前記空洞化センサおよび沸騰センサによってとられた測定値によって制御される、請求項1に記載の高強度集束超音波トランスデューサー。
- 光学センサをさらに備える、請求項に1に記載の高強度集束超音波トランスデューサーであって、前記複数のトランスデューサー要素の各々の位置、速度、および回転のうちの少なくとも1つが、該光学センサを使用して決定される、高強度集束超音波トランスデューサー。
- 前記光学センサが、直交バーコード格子に対して応答性であり、該直交バーコード格子は、患者の身体上に印刷された擬似ランダム配列を含む、請求項3に記載の高強度集束超音波トランスデューサー。
- ボールおよびソケットセンサをさらに備える、請求項1に記載の高強度集束超音波トランスデューサーであって、前記複数のトランスデューサー要素の各々の位置、速度、および回転のうちの少なくとも1つが、該ボールおよびソケットセンサを使用して決定される、高強度集束超音波トランスデューサー。
- 光学センサをさらに備える、請求項に1に記載の高強度集束超音波トランスデューサーであって、前記複数のトランスデューサー要素の各々によって適用されるべき処置エネルギーに関する情報が、該光学センサを使用して決定される、高強度集束超音波トランスデューサー。
- 請求項6に記載の高強度集束超音波トランスデューサーであって、領域にわたる該トランスデューサーの適用範囲を示して、該トランスデューサーからの超音波エネルギーを受け取るための前記トランスデューサー要素に接続された複数のLEDをさらに備える、高強度集束超音波トランスデューサー。
- 前記複数のLEDが、患者の身体に適用される色素に対して応答性である、請求項7に記載の高強度集束超音波トランスデューサー。
- 超音波センサをさらに備える、請求項1に記載の高強度集束超音波トランスデューサーであって、前記複数のトランスデューサー要素の各々の位置が、該超音波センサを使用して決定される、高強度集束超音波トランスデューサー。
- 超音波センサをさらに備える、請求項1に記載の高強度集束超音波トランスデューサーであって、前記複数のトランスデューサー要素の各々によって適用されるべき処置エネルギーに関する情報が、該超音波センサを使用して決定される、高強度集束超音波トランスデューサー。
- 請求項1に記載の高強度集束超音波トランスデューサーであって、前記トランスデューサー要素の各々が、以下:
圧電要素;および
該圧電要素に接続された、少なくとも2つの材料を含む、フレネル型レンズ、
を備える、高強度集束超音波トランスデューサー。 - 前記トランスデューサーが、器官組織から該トランスデューサーを分離するための固体プラスチック材料を含む、請求項1に記載の高強度集束超音波トランスデューサー。
- 前記トランスデューサー要素の各々が、複数のエネルギー光線を生成するための機械的変調器を備える、請求項1に記載の高強度集束超音波トランスデューサー。
- 前記トランスデューサー要素の各々が、単結晶圧電セラミック要素を備える、請求項1に記載の高強度集束超音波トランスデューサー。
- 請求項1に記載の高強度集束超音波トランスデューサーであって、
前記トランスデューサー要素の各々が、複数の光線を生成し得;そして
前記トランスデューサー要素の各々が、互いに独立して操作可能である、高強度集束超音波トランスデューサー。 - 前記トランスデューサーが、単一スポットに対して異なる周波数の2つの光線を同時に放射し得る、請求項1に記載の高強度集束超音波トランスデューサー。
- 前記複数のトランスデューサー要素が、乱光線経路を生成するパターンで配置される、請求項1に記載の高強度集束超音波トランスデューサー。
- 脂肪の厚さを測定するためのAトレースセンサをさらに備える、請求項1に記載の高強度集束超音波トランスデューサー。
- 前記トランスデューサーの位置が、コンピューターに保存された患者の身体のデータを含む仮想データに従って決定される、請求項1に記載の高強度集束超音波トランスデューサー。
- 高強度集束超音波トランスデューサーアセンブリであって、以下:
1つ以上のトランスデューサー要素;ならびに
該高強度集束超音波トランスデューサーが、手動で操作され得る、複数の運動センサおよび組織センサ、
を備える、高強度集束超音波トランスデューサーアセンブリ。 - 受動的画像化デバイスであって、以下:
器官組織の空洞化または沸騰によって発生された音響を検出するように適合された、複数のセンサ;および
該複数のセンサによって検出された音響に対応する画像を表示するように適合される、表示デバイス、
を備える、受動的画像化デバイス。 - 器官組織に超音波エネルギーを適用する方法であって、該方法は、以下:
一連のオン/オフサイクルでトランスデューサーから器官組織へ超音波エネルギーを放射して、それにより、該放射の間に生成された熱が、該一連のオン/オフサイクルにおける連続したオンサイクルの間に、該トランスデューサーから伝導されない、工程、
を包含する、方法。 - 前記トランスデューサーが、平均電力を維持しながらピーク電力で操作される、請求項22に記載の超音波エネルギーを適用する方法。
- 前記トランスデューサーが、空冷により冷却される、請求項22に記載の超音波エネルギーを適用する方法。
- 患者から除去されるべき脂肪組織を同定する方法であって、以下:
光学カメラの線形アレイおよび超音波画像化システムを用いて患者を画像化して、一定の脂肪の厚さの外形をマークする、工程;
画像化工程からの画像を印刷することによって皮膚フィンガープリントを作製する工程;ならびに
異なる色のインクを用いて個体の脂肪の厚さを同定する工程、
を包含する、方法。 - 患者の身体内で高強度集束超音波(HIFU)を利用する、脂肪組織の破壊のためのシステムであって、該システムは、以下:
データの電気的保存および複数のシステム構成要素を制御するための、コントローラー;
ヒトの身体をマッピングして、該ヒト内の既存の脂肪組織についての3次元座標位置データを確立するための手段であって、該コントローラーは、該ヒトの身体上の複数の脂肪組織位置を同定し、そして脂肪組織破壊のためのプロトコルを確立し得る、手段;
高強度集束超音波を放射するための1つ以上の圧電要素、および少なくとも1つのセンサを有するトランスデューサーアセンブリであって、該センサは、該1つ以上の圧電要素の安全な操作のために、該コントローラーにフィードバック情報を提供する、トランスデューサーアセンブリ、
を備え、
ここで、該少なくとも1つのセンサは、該コントローラーに電気的に接続されており、そして該コントローラーは、該3次元座標位置データから得られる位置決め情報に基づいて、該1つ以上の圧電要素に必須処置命令情報を提供する、システム。 - 処置表をさらに備える、請求項26に記載のシステムであって、該処置表は、該表に存在する複数の固定された同定可能な位置を有し、それにより、前記マッピング成分が、該固定された同定可能な位置の使用により、該表上のヒトの身体の相対位置を同定し得る、システム。
- 前記固定された同定可能な位置が、複数の電気的位置マーカーまたは磁気位置マーカーである、請求項27に記載のシステム。
- 前記システムの構成要素の1つ以上が、ガントリーを利用して操作可能であるように、前記患者の身体について三次元の移動範囲を有する該ガントリーをさらに備える、請求項26に記載のシステム。
- 前記トランスデューサーアセンブリが、さらに以下:
沸騰センサ;
空洞化センサ;ならびに
該沸騰センサおよび空洞化センサに接続された1つ以上の圧電要素、
を備える、請求項26に記載のシステム。 - 前記圧電要素の各々によって放出されるエネルギーの量が、前記空洞化センサおよび前記沸騰センサによって取得される測定値によって制御される、請求項26に記載のシステム。
- 光学センサをさらに備える、請求項26に記載のシステムであって、前記1つ以上の圧電要素の位置、速度、および回転のうちの少なくとも1つが、該光学センサを使用して決定される、システム。
- 前記光学センサが、直交バーコード格子に応答性であり、該直交バーコード格子は、患者の身体上に印刷された擬似ランダム配列を含む、請求項32に記載のシステム。
- ボールおよびソケットセンサをさらに備える、請求項26に記載のシステムであって、前記1つ以上の圧電要素の位置、速度、および回転のうちの少なくとも1つが、該ボールおよびソケットセンサを使用して決定される、システム。
- 光学センサをさらに備える、請求項26に記載のシステムであって、前記1つ以上の圧電要素の各々によって印加される処置エネルギーに関する情報が、該光学センサを使用して決定される、システム。
- 前記1つ以上の圧電要素から超音波エネルギーを受け取る領域にわたって、前記トランスデューサーアセンブリの適用範囲を示すための該トランスデューサーアセンブリに接続された、複数のLEDをさらに備える、請求項35に記載のシステム。
- 前記複数のLEDが、前記患者の身体に塗布された染料に応答する、請求項36に記載のシステム。
- 超音波センサをさらに備える、請求項26に記載のシステムであって、前記1つの以上の圧電要素の各々の位置が、該超音波センサを使用して決定される、システム。
- 画像化超音波センサをさらに備える、請求項26に記載のシステムであって、前記1つ以上の圧電要素の各々によって印加される処置エネルギーに関する情報が、該画像化超音波センサを使用して決定される、システム。
- 前記1つ以上の圧電要素の各々が、該圧電要素に接続されたフレネル型レンズを備える、請求項26に記載のシステムであって、該フレネル型レンズが、少なくとも2つの材料を含む、システム。
- 前記1つ以上の圧電要素の各々が、複数のエネルギー光線を生成する機械的変調器を備える、請求項26に記載のシステム。
- 前記1つ以上の圧電要素の各々が、複数のビームを生成し得;そして該1つ以上の圧電要素が、互いに独立して操作可能である、請求項26に記載のシステム。
- 前記変換機アセンブリが、単一スポットに対して、異なる周波数の、2つ以上のHIFUビームを同時に放射し得る、請求項26に記載のシステム。
- 前記1つ以上の圧電要素が、乱光線経路を生成するパターンで配置される、請求項26に記載のシステム。
- 脂肪の厚みを測定するためのAトレースセンサをさらに備える、請求項26に記載のシステム。
- 前記変換機アセンブリの位置が、コンピューターに保存された患者の身体のデータを含む仮想格子に従って決定される、請求項26に記載のシステム。
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Also Published As
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EP1476080A4 (en) | 2010-06-02 |
US7841984B2 (en) | 2010-11-30 |
US20080015435A1 (en) | 2008-01-17 |
US7258674B2 (en) | 2007-08-21 |
AU2003219843A1 (en) | 2003-09-09 |
WO2003070105A1 (en) | 2003-08-28 |
US20040039312A1 (en) | 2004-02-26 |
CA2476873A1 (en) | 2003-08-28 |
JP4551090B2 (ja) | 2010-09-22 |
EP1476080A1 (en) | 2004-11-17 |
AU2003219843B2 (en) | 2009-04-23 |
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