JP2005515214A - 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置 - Google Patents

組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置 Download PDF

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JP2005515214A
JP2005515214A JP2003556020A JP2003556020A JP2005515214A JP 2005515214 A JP2005515214 A JP 2005515214A JP 2003556020 A JP2003556020 A JP 2003556020A JP 2003556020 A JP2003556020 A JP 2003556020A JP 2005515214 A JP2005515214 A JP 2005515214A
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tfpi
ala
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glycosylated
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JP2005515214A5 (OSRAM
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アルバ エー． クリージー，
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カイロン コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2003556020A 2001-10-15 2002-10-15 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置 Withdrawn JP2005515214A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32880601P 2001-10-15 2001-10-15
PCT/US2002/032625 WO2003055442A2 (en) 2001-10-15 2002-10-15 Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)

Related Child Applications (1)

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JP2005271191A Division JP2006008704A (ja) 2001-10-15 2005-09-16 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置

Publications (2)

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JP2005515214A true JP2005515214A (ja) 2005-05-26
JP2005515214A5 JP2005515214A5 (OSRAM) 2006-01-05

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Family Applications (5)

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JP2003535710A Withdrawn JP2005506345A (ja) 2001-10-15 2002-10-15 組織因子経路インヒビター（ｔｆｐｉ）の投与による重症な肺炎の処置
JP2003556020A Withdrawn JP2005515214A (ja) 2001-10-15 2002-10-15 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置
JP2005271219A Pending JP2006008706A (ja) 2001-10-15 2005-09-16 組織因子経路インヒビター（ｔｆｐｉ）の投与による重症な肺炎の処置
JP2005271191A Withdrawn JP2006008704A (ja) 2001-10-15 2005-09-16 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置
JP2009235793A Withdrawn JP2010006839A (ja) 2001-10-15 2009-10-09 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置

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JP2003535710A Withdrawn JP2005506345A (ja) 2001-10-15 2002-10-15 組織因子経路インヒビター（ｔｆｐｉ）の投与による重症な肺炎の処置

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JP2005271219A Pending JP2006008706A (ja) 2001-10-15 2005-09-16 組織因子経路インヒビター（ｔｆｐｉ）の投与による重症な肺炎の処置
JP2005271191A Withdrawn JP2006008704A (ja) 2001-10-15 2005-09-16 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置
JP2009235793A Withdrawn JP2010006839A (ja) 2001-10-15 2009-10-09 組織因子経路インヒビター（ｔｆｐｉ）の低量投与による敗血症の処置

Country Status (17)

Country Link
US (2) US7674769B2 (OSRAM)
EP (2) EP1446140A4 (OSRAM)
JP (5) JP2005506345A (OSRAM)
KR (2) KR20050036867A (OSRAM)
CN (2) CN1604790A (OSRAM)
AU (2) AU2002365131B2 (OSRAM)
BR (2) BR0213293A (OSRAM)
CA (2) CA2463738A1 (OSRAM)
EA (2) EA200400548A1 (OSRAM)
HU (2) HUP0500472A2 (OSRAM)
IL (2) IL161407A0 (OSRAM)
IS (2) IS7224A (OSRAM)
MX (2) MXPA04003547A (OSRAM)
NO (2) NO20041996D0 (OSRAM)
PL (2) PL372138A1 (OSRAM)
WO (2) WO2003055442A2 (OSRAM)
ZA (2) ZA200403601B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009502810A (ja) * 2005-07-22 2009-01-29 ノバルティス アクチエンゲゼルシャフト 補体系と相互作用する抗微生物剤
WO2013073545A1 (ja) * 2011-11-15 2013-05-23 旭化成ファーマ株式会社 敗血症の治療及び／又は改善のための医薬

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ATE516306T1 (de) 2003-08-13 2011-07-15 Novartis Vaccines & Diagnostic Verbessertes verfahren zur reinigung von tfpi und tfpi-analogen
MXPA06010587A (es) * 2004-03-17 2007-03-29 Chiron Corp Tratamiento de neumonia severa adquirida en comunidad por administracion del inhibidor de la via del factor tisular (tfpi).
CN101180074A (zh) * 2005-04-15 2008-05-14 诺华疫苗和诊断公司 通过施用组织因子通路抑制剂(tfpi)治疗严重社区获得性肺炎
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JP5757495B2 (ja) 2005-05-16 2015-07-29 アッヴィ バイオテクノロジー リミテッド びらん性多発性関節炎の治療のためのｔｎｆ阻害剤の使用
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009502810A (ja) * 2005-07-22 2009-01-29 ノバルティス アクチエンゲゼルシャフト 補体系と相互作用する抗微生物剤
WO2013073545A1 (ja) * 2011-11-15 2013-05-23 旭化成ファーマ株式会社 敗血症の治療及び／又は改善のための医薬
JPWO2013073545A1 (ja) * 2011-11-15 2015-04-02 旭化成ファーマ株式会社 敗血症の治療及び／又は改善のための医薬
US9555080B2 (en) 2011-11-15 2017-01-31 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis
US9592275B2 (en) 2011-11-15 2017-03-14 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis

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EP1446140A4 (en) 2007-03-07
IL161407A0 (en) 2004-09-27
NO20041997D0 (no) 2004-05-14
WO2003032904A2 (en) 2003-04-24
IS7224A (is) 2004-04-15
US20030139339A1 (en) 2003-07-24
KR20050036867A (ko) 2005-04-20
ZA200403601B (en) 2006-06-28
IL161408A0 (en) 2004-09-27
WO2003055442A3 (en) 2004-03-04
US7674769B2 (en) 2010-03-09
AU2002340183B2 (en) 2008-11-13
JP2006008706A (ja) 2006-01-12
CA2463738A1 (en) 2003-07-10
EA200400549A1 (ru) 2005-02-24
PL372138A1 (en) 2005-07-11
BR0213292A (pt) 2006-05-23
AU2002365131A1 (en) 2003-07-15
EP1446138A2 (en) 2004-08-18
CA2463655A1 (en) 2003-04-24
IS7223A (is) 2004-04-15
EP1446140A2 (en) 2004-08-18
HUP0501111A2 (en) 2007-12-28
NO20041996D0 (no) 2004-05-14
EP1446138A4 (en) 2007-03-14
PL374506A1 (en) 2005-10-31
EA200400548A1 (ru) 2005-06-30
AU2002365131B2 (en) 2007-03-01
CN1604787A (zh) 2005-04-06
ZA200403690B (en) 2005-03-08
JP2010006839A (ja) 2010-01-14
CN1604790A (zh) 2005-04-06
KR20040040489A (ko) 2004-05-12
JP2006008704A (ja) 2006-01-12
HUP0500472A2 (hu) 2005-08-29
MXPA04003548A (es) 2004-07-22
WO2003032904A3 (en) 2004-03-04
BR0213293A (pt) 2004-12-21
US20030139340A1 (en) 2003-07-24
MXPA04003547A (es) 2004-07-22
WO2003055442A2 (en) 2003-07-10
JP2005506345A (ja) 2005-03-03

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