|
US7119120B2
(en)
*
|
2001-12-26 |
2006-10-10 |
Genzyme Corporation |
Phosphate transport inhibitors
|
|
US7119112B2
(en)
*
|
2002-02-28 |
2006-10-10 |
Icagen, Inc. |
Sulfonamides as potassium channel blockers
|
|
US20040161474A1
(en)
*
|
2002-05-24 |
2004-08-19 |
Moerck Rudi E. |
Rare earth metal compounds methods of making, and methods of using the same
|
|
US20060083791A1
(en)
*
|
2002-05-24 |
2006-04-20 |
Moerck Rudi E |
Rare earth metal compounds methods of making, and methods of using the same
|
|
US20060160856A1
(en)
*
|
2002-09-05 |
2006-07-20 |
Dahl Bjarne H |
Diarylurea derivatives and their use as chloride channel blockers
|
|
EP1398029A1
(en)
*
|
2002-09-10 |
2004-03-17 |
LION Bioscience AG |
NR3B1 nuclear receptor binding 3-substituted pyrazole derivatives
|
|
US7491718B2
(en)
*
|
2002-10-08 |
2009-02-17 |
Abbott Laboratories |
Sulfonamides having antiangiogenic and anticancer activity
|
|
WO2004037274A1
(en)
*
|
2002-10-22 |
2004-05-06 |
Genzyme Corporation |
Amine polymers for promoting bone formation
|
|
DE10257357A1
(de)
|
2002-12-09 |
2004-06-24 |
Bayer Ag |
Fluorhaltige Benzaldehyde
|
|
EP1753421B1
(en)
|
2004-04-20 |
2012-08-01 |
Amgen Inc. |
Arylsulfonamides and uses as hydroxysteroid dehydrogenase
|
|
CA2583548A1
(en)
*
|
2004-10-15 |
2006-04-27 |
Altairnano, Inc. |
Phosphate binder with reduced pill burden
|
|
WO2006077901A1
(ja)
*
|
2005-01-20 |
2006-07-27 |
Shionogi & Co., Ltd. |
Ctgf発現阻害剤
|
|
WO2007022466A2
(en)
*
|
2005-08-17 |
2007-02-22 |
Altairnano, Inc. |
Hyperphosphatemia in domestic animals: compositions and methods of treatment
|
|
JP2009504779A
(ja)
*
|
2005-08-17 |
2009-02-05 |
アルテアナノ インコーポレイテッド |
家畜における慢性腎不全及びその他の病気の治療:組成物及び方法
|
|
DE102005044156A1
(de)
*
|
2005-09-15 |
2007-03-29 |
Riemser Arzneimittel Ag |
Substituierte Acetophenonderivate
|
|
GB0526252D0
(en)
*
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
GB0526255D0
(en)
*
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
JP2009542653A
(ja)
*
|
2006-07-05 |
2009-12-03 |
ジェンザイム コーポレーション |
リン酸塩過剰血症のための鉄(ii)含有治療剤
|
|
WO2009017863A2
(en)
|
2007-05-08 |
2009-02-05 |
Burnham Institute For Medical Research |
Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification
|
|
US7776877B2
(en)
|
2007-06-22 |
2010-08-17 |
Chemocentryx, Inc. |
N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
|
|
JP2011523655A
(ja)
*
|
2008-06-03 |
2011-08-18 |
フレセニウス メディカル ケア ドイッチュランド ゲーエムベーハー |
ガンマセクレターゼモジュレータを含む医薬組成物
|
|
US20110293520A1
(en)
|
2008-06-09 |
2011-12-01 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
New drug for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases
|
|
CA2729767A1
(en)
*
|
2008-07-07 |
2010-01-14 |
Fasgen, Inc. |
Novel compounds, pharmaceutical compositions containing same, methods of use for same, and methods for preparing same
|
|
EP3351248B1
(en)
|
2008-12-31 |
2021-06-09 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
WO2018129556A1
(en)
|
2017-01-09 |
2018-07-12 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
EP3351250A3
(en)
|
2009-01-26 |
2018-10-17 |
Opko Ireland Global Holdings, Ltd. |
Phosphate management with small molecules
|
|
AU2010303270A1
(en)
|
2009-10-09 |
2012-05-03 |
Zafgen Corporation |
Sulphone compounds for use in the treatment of obesity
|
|
ES2561672T3
(es)
*
|
2010-03-05 |
2016-02-29 |
Duophos |
Inhibidores de fluorofosfato de arilo del cotransporte sodio/fosfato de la membrana apical intestinal
|
|
RU2570007C2
(ru)
|
2010-05-12 |
2015-12-10 |
Спектрум Фармасьютикалз, Инк. |
Гидроксид карбонат лантана, оксикарбонат лантана и способы их получения и применения
|
|
EP2590656B1
(en)
|
2010-07-07 |
2017-11-15 |
Ardelyx, Inc. |
Compounds and methods for inhibiting phosphate transport
|
|
WO2012006473A1
(en)
|
2010-07-07 |
2012-01-12 |
Ardelyx, Inc. |
Compounds and methods for inhibiting phosphate transport
|
|
WO2012006477A1
(en)
|
2010-07-07 |
2012-01-12 |
Ardelyx, Inc. |
Compounds and methods for inhibiting phosphate transport
|
|
EP2590965B1
(en)
*
|
2010-07-07 |
2016-04-20 |
Ardelyx, Inc. |
Compounds and methods for inhibiting phosphate transport
|
|
WO2012012642A1
(en)
|
2010-07-22 |
2012-01-26 |
Zafgen Corporation |
Tricyclic compounds and methds of making and using same
|
|
WO2012103333A1
(en)
|
2011-01-26 |
2012-08-02 |
Zafgen Corporation |
Tetrazole compounds and methods of making and using same
|
|
US9290472B2
(en)
|
2011-05-06 |
2016-03-22 |
Zafgen, Inc. |
Partially saturated tricyclic compounds and methods of making and using same
|
|
BR112013028665A2
(pt)
|
2011-05-06 |
2016-09-06 |
Zafgen Inc |
compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos
|
|
CN103764652B
(zh)
|
2011-05-06 |
2016-03-23 |
扎夫根股份有限公司 |
三环吡唑磺酰胺化合物及其制备和使用方法
|
|
CA2861390A1
(en)
|
2012-01-18 |
2013-07-25 |
Zafgen, Inc. |
Tricyclic sulfonamide compounds and methods of making and using same
|
|
CA2861381A1
(en)
|
2012-01-18 |
2013-07-25 |
Zafgen, Inc. |
Tricyclic sulfone compounds and methods of making and using same
|
|
CA2880338A1
(en)
|
2012-08-21 |
2014-02-27 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
US10376481B2
(en)
|
2012-08-21 |
2019-08-13 |
Ardelyx, Inc. |
Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
KR20150080614A
(ko)
|
2012-11-05 |
2015-07-09 |
자프겐 인크. |
비만의 치료 및/또는 제어에서 사용하기 위한 트리시클릭 화합물
|
|
NZ707773A
(en)
|
2012-11-05 |
2019-05-31 |
Zafgen Inc |
Methods of treating liver diseases
|
|
MX2015005732A
(es)
|
2012-11-05 |
2015-12-16 |
Zafgen Inc |
Compuestos tricíclicos y métodos para hacer y utilizar los mismos.
|
|
KR102287207B1
(ko)
|
2013-04-12 |
2021-08-09 |
알데릭스, 인코포레이티드 |
Nhe3-결합 화합물 및 포스페이트 수송을 저해하는 방법
|
|
CN103467452B
(zh)
*
|
2013-09-11 |
2015-11-18 |
陕西理工学院 |
一种苯甲酰胺类化合物及其应用
|
|
CN106008360B
(zh)
*
|
2016-08-11 |
2018-10-16 |
华南农业大学 |
一种对氨基苯磺酰咪唑及其制备方法
|
|
JOP20190080A1
(ar)
|
2016-10-14 |
2019-04-11 |
Bayer Pharma AG |
مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
|
|
US11046683B2
(en)
*
|
2016-12-15 |
2021-06-29 |
Ono Pharmaceutical Co., Ltd. |
Activator of TREK (TWIK RElated K+ channels) channels
|
|
CN110267944B
(zh)
|
2017-01-09 |
2024-03-08 |
阿德利克斯股份有限公司 |
可用于治疗胃肠道病症的化合物
|
|
JP2020505333A
(ja)
|
2017-01-09 |
2020-02-20 |
アルデリックス, インコーポレイテッド |
Nhe媒介性アンチポートの阻害薬
|
|
WO2019028343A1
(en)
*
|
2017-08-03 |
2019-02-07 |
Georgetown University |
SMALL MOLECULE INHIBITORS OF SLC25A1
|
|
BR112020014561A2
(pt)
|
2018-01-17 |
2020-12-08 |
Migal - Galilee Research Institute Ltd. |
Nibidores inovadores da via metabólica da metionina
|
|
WO2019142192A1
(en)
|
2018-01-17 |
2019-07-25 |
Gavish-Galilee Bio Applications Ltd. |
New methionine metabolic pathway inhibitors
|
|
CN110305045A
(zh)
*
|
2018-03-20 |
2019-10-08 |
成都海创药业有限公司 |
一种酰胺类化合物及其在治疗癌症中的用途
|
|
EP3802514B1
(en)
|
2018-06-01 |
2022-08-03 |
Promega Corporation |
Inhibitors of oplophorus luciferase-derived bioluminescent complexes
|
|
CA3133803A1
(en)
|
2019-04-11 |
2020-10-15 |
Angion Biomedica Corp. |
Solid forms of (e)-3-[2-(2-thienyl)vinyl]-1h-pyrazole
|
|
WO2021041561A2
(en)
*
|
2019-08-26 |
2021-03-04 |
Avantaggiati Mauria Laura |
Treating non-alcoholic fatty liver disease and inflammatory steatohepatitis with slc25a1 inhibitors
|
|
US20250302833A1
(en)
*
|
2022-05-11 |
2025-10-02 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for treating or preventing cystic disease
|