JP2005507692A - 生物薬剤材料を凍結及び貯蔵するためのシステム、及びその方法 - Google Patents
生物薬剤材料を凍結及び貯蔵するためのシステム、及びその方法 Download PDFInfo
- Publication number
- JP2005507692A JP2005507692A JP2003539440A JP2003539440A JP2005507692A JP 2005507692 A JP2005507692 A JP 2005507692A JP 2003539440 A JP2003539440 A JP 2003539440A JP 2003539440 A JP2003539440 A JP 2003539440A JP 2005507692 A JP2005507692 A JP 2005507692A
- Authority
- JP
- Japan
- Prior art keywords
- container
- control unit
- temperature control
- biopharmaceutical material
- biopharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 200
- 229960000074 biopharmaceutical Drugs 0.000 title claims abstract description 177
- 238000007710 freezing Methods 0.000 title claims abstract description 77
- 230000008014 freezing Effects 0.000 title claims abstract description 77
- 238000000034 method Methods 0.000 title claims description 26
- 238000010257 thawing Methods 0.000 claims abstract description 28
- 239000012530 fluid Substances 0.000 claims abstract description 9
- 230000006835 compression Effects 0.000 claims description 8
- 238000007906 compression Methods 0.000 claims description 8
- 238000005304 joining Methods 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 230000000295 complement effect Effects 0.000 claims 1
- 238000003860 storage Methods 0.000 abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 28
- 239000013078 crystal Substances 0.000 description 25
- 238000001816 cooling Methods 0.000 description 13
- 239000007788 liquid Substances 0.000 description 13
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- 239000004033 plastic Substances 0.000 description 4
- 239000004952 Polyamide Substances 0.000 description 3
- 238000005138 cryopreservation Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
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- 229920000728 polyester Polymers 0.000 description 2
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- 238000005507 spraying Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
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- 238000004781 supercooling Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
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- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
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- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
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- 239000007789 gas Substances 0.000 description 1
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- 239000013529 heat transfer fluid Substances 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 239000005001 laminate film Substances 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
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- 229920000915 polyvinyl chloride Polymers 0.000 description 1
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- 238000001556 precipitation Methods 0.000 description 1
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- 239000003507 refrigerant Substances 0.000 description 1
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- 150000003839 salts Chemical class 0.000 description 1
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Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D31/00—Other cooling or freezing apparatus
- F25D31/001—Plate freezers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/142—Apparatus
- A01N1/144—Apparatus for temperature control, e.g. refrigerators or freeze-drying apparatus
- A01N1/145—Stationary or portable vessels generating cryogenic temperatures, e.g. liquid nitrogen baths
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/146—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/80—Freezing; Subsequent thawing; Cooling
- A23B2/805—Materials not being transported through or in the apparatus with or without shaping, e.g. in the form of powders, granules or flakes
- A23B2/8055—Materials not being transported through or in the apparatus with or without shaping, e.g. in the form of powders, granules or flakes with packages or with shaping in the form of blocks or portions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/80—Freezing; Subsequent thawing; Cooling
- A23B2/82—Thawing subsequent to freezing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
- A61M1/0277—Frames constraining or supporting bags, e.g. during freezing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D25/00—Charging, supporting, and discharging the articles to be cooled
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B2600/00—Control issues
- F25B2600/07—Remote controls
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
- F25D2331/80—Type of cooled receptacles
- F25D2331/801—Bags
- F25D2331/8014—Bags for medical use
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
- F25D2400/20—Carts specially adapted for transporting objects to be cooled
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
- F25D2400/30—Quick freezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2500/00—Problems to be solved
- F25D2500/02—Geometry problems
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Combustion & Propulsion (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Environmental Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Packages (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33462201P | 2001-11-01 | 2001-11-01 | |
| PCT/US2002/035137 WO2003037083A1 (en) | 2001-11-01 | 2002-11-01 | Systems and methods for freezing and storing biopharmacuetical material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2005507692A true JP2005507692A (ja) | 2005-03-24 |
Family
ID=23308033
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003539440A Pending JP2005507692A (ja) | 2001-11-01 | 2002-11-01 | 生物薬剤材料を凍結及び貯蔵するためのシステム、及びその方法 |
| JP2003539439A Pending JP2005523843A (ja) | 2001-11-01 | 2002-11-01 | 生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003539439A Pending JP2005523843A (ja) | 2001-11-01 | 2002-11-01 | 生物薬剤材料を凍結、貯蔵及び解凍するためのシステム、及びその方法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1441586B1 (enExample) |
| JP (2) | JP2005507692A (enExample) |
| CN (3) | CN1229018C (enExample) |
| AT (2) | ATE326841T1 (enExample) |
| CA (2) | CA2466130A1 (enExample) |
| DE (2) | DE60212680T2 (enExample) |
| DK (2) | DK1441586T3 (enExample) |
| ES (2) | ES2265057T3 (enExample) |
| WO (2) | WO2003037082A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007023907A1 (ja) * | 2005-08-24 | 2007-03-01 | Transcu Ltd. | 冷凍型イオントフォレーシス用電極構造体 |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006500285A (ja) * | 2002-09-23 | 2006-01-05 | インテグレーティッド バイオシステムズ，インコーポレーティッド | 生物医薬原料を凍結、貯蔵、輸送、及び解凍するシステム |
| CA2509037A1 (en) * | 2002-12-13 | 2004-07-01 | Integrated Biosystems, Inc. | Scaled down freezing and thawing system for bioparmaceuticals and biologics |
| DE102004015090A1 (de) | 2004-03-25 | 2005-11-03 | Hüttinger Elektronik Gmbh + Co. Kg | Bogenentladungserkennungseinrichtung |
| JP4939405B2 (ja) | 2005-04-28 | 2012-05-23 | 株式会社大塚製薬工場 | 薬液容器収容体およびその製造方法 |
| US20090217677A1 (en) * | 2005-12-02 | 2009-09-03 | Youn-Ok Shin | Freezing and storage container for biopharmaceutical drug products |
| US8028532B2 (en) * | 2006-03-06 | 2011-10-04 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
| CN101563057B (zh) * | 2006-10-27 | 2015-04-15 | 株式会社大塚制药工厂 | 溶解氧减少的液体制剂的制备方法、以及溶解氧含量减少的药液收容体 |
| WO2009086136A2 (en) * | 2007-12-21 | 2009-07-09 | Sartorius Stedim Systems Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
| US9301520B2 (en) | 2007-12-21 | 2016-04-05 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
| US8177123B2 (en) * | 2008-09-24 | 2012-05-15 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
| CA2749978A1 (en) * | 2009-01-20 | 2010-07-29 | F. Hoffmann-La Roche Ag | Cryogenic container |
| US20110017743A1 (en) * | 2009-07-22 | 2011-01-27 | Honeywell International Inc. | Sealable container linings and sealable containers |
| US8371132B2 (en) * | 2009-11-23 | 2013-02-12 | Sartorius Stedim North America Inc. | Systems and methods for use in freezing, thawing, and storing biopharmaceutical materials |
| IT1397926B1 (it) * | 2010-02-12 | 2013-02-04 | Angelantoni Ind Spa | Congelatore rapido per sacche con rilevazione della temperatura delle sacche. |
| PT105405B (pt) * | 2010-11-26 | 2014-08-21 | Univ Lisboa | Processo e aparelho de congelação em pratos para obtenção de matrizes de gelo com distribuição de solutos uniforme |
| CN104081142B (zh) * | 2011-03-28 | 2017-03-01 | 普莱克斯技术有限公司 | 生物制药的散装冻结 |
| CN102322725B (zh) * | 2011-09-13 | 2013-06-12 | 东莞市品翔饮水设备有限公司 | 制冰、制冷、制热直饮机 |
| DE102012007904B4 (de) * | 2012-04-23 | 2015-08-27 | Fresenius Medical Care Deutschland Gmbh | Beutel mit verbundenem biegesteifen Kunststoffteil |
| US9357766B2 (en) * | 2012-07-10 | 2016-06-07 | Lifeline Scientific, Inc. | Organ transport apparatus with a document compartment and a tamper evident seal |
| US9441893B2 (en) * | 2012-07-25 | 2016-09-13 | Grifols, S.A. | Thawing vessel for biological products |
| BR112015009137A2 (pt) * | 2012-10-31 | 2017-07-04 | Pluristem Ltd | método para descongelamento de material biológico congelado, e, sistema para o aquecimento de um material biológico em um recipiente |
| FR3003644B1 (fr) | 2013-03-22 | 2015-03-20 | Sartorius Stedim North America Inc | Controle de l'etat de congelation d'un fluide biopharmaceutique se trouvant dans un conteneur. |
| FR3003550B1 (fr) | 2013-03-22 | 2016-05-06 | Sartorius Stedim North America Inc | Installation et procede pour la preparation d'un conteneur charge avec un fluide biopharmaceutique. |
| CN103392691B (zh) * | 2013-08-14 | 2015-09-23 | 北京瑞健高科生物科技有限公司 | 一种生物组织处理、灭菌及保存的容器和方法 |
| PT107427B (pt) * | 2014-01-28 | 2021-01-04 | Inst Superior Tecnico | Sistema e método de preservação, armazenamento e transporte de materiais biológicos. |
| CA2957526C (en) | 2014-08-08 | 2023-03-28 | Fremon Scientific, Inc. | Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance |
| EP3199023B1 (en) | 2016-01-27 | 2021-01-20 | Sartorius Stedim North America Inc. | Method and system for freezing biopharmaceutical fluid |
| JP6696870B2 (ja) * | 2016-09-23 | 2020-05-20 | 大陽日酸株式会社 | 液体用バッグの急速凍結方法および急速凍結装置 |
| US11304874B2 (en) * | 2016-11-04 | 2022-04-19 | Sartorius Stedim North America, Inc. | Protecting body for a flexible pouch, system for containing a biopharmaceutical fluid and methods for using such a system |
| JP6872369B2 (ja) * | 2017-01-11 | 2021-05-19 | 藤森工業株式会社 | 注出口付き包装袋 |
| CN108357763B (zh) * | 2018-02-13 | 2019-07-16 | 京东方科技集团股份有限公司 | 一种生物片材存储装置 |
| CN108353890B (zh) * | 2018-02-13 | 2021-01-26 | 京东方科技集团股份有限公司 | 一种生物片材固定装置 |
| EP3772934B1 (en) * | 2018-03-29 | 2024-08-07 | W. L. Gore & Associates, Inc. | Carrier for freezing, storing, transporting, and thawing biological products storage bags |
| WO2019200145A1 (en) * | 2018-04-11 | 2019-10-17 | Astero Bio Corporation | Systems and methods for cryostorage bag protection |
| WO2019217488A1 (en) | 2018-05-07 | 2019-11-14 | Fremon Scientific, Inc. | Thawing biological substances |
| NL2023121B1 (en) * | 2019-05-13 | 2020-12-01 | Nutritious Juices & Soups B V | Food product dispensing system |
| CN111503978A (zh) * | 2020-04-27 | 2020-08-07 | 上海东富龙科技股份有限公司 | 一种用于生物制药材料冷冻、解冻工艺的装置 |
| CN111503959A (zh) * | 2020-04-27 | 2020-08-07 | 上海东富龙科技股份有限公司 | 一种用于生物制药材料冷冻、解冻工艺处理的冻融机 |
| CN111503997B (zh) * | 2020-04-27 | 2022-02-08 | 上海东富龙科技股份有限公司 | 一种用于生物制药材料冷冻、解冻或混合工艺处理的冻融系统 |
| US11571359B2 (en) | 2020-07-30 | 2023-02-07 | Sartorius Stedim North America | Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body |
| US11590056B2 (en) | 2020-07-30 | 2023-02-28 | Sartorius Stedim North America | Freeze/thaw containment system for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body |
| US11590055B2 (en) | 2020-07-30 | 2023-02-28 | Sartorius Stedim North America | Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body |
| EP3960640A1 (en) | 2020-08-28 | 2022-03-02 | Sartorius Stedim Biotech GmbH | Safety device for a single-use mixing or storage system |
| US12239127B2 (en) | 2021-07-28 | 2025-03-04 | Sartorius Stedim North America Inc. | Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials |
| JP7649231B2 (ja) * | 2021-11-10 | 2025-03-19 | 大陽日酸株式会社 | 予備凍結用ラック及び予備凍結方法 |
| CN114471754A (zh) * | 2021-12-27 | 2022-05-13 | 利穗科技(苏州)有限公司 | 一种用于生物材料水溶液的容器 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2557870A1 (de) * | 1975-12-22 | 1977-06-23 | Linde Ag | Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen |
| DE3238535A1 (de) * | 1982-10-18 | 1984-04-19 | Planer Products Ltd., Sunbury-on-Thames, Middlesex | Verfahren und apparat zum gesteuerten kuehlen eines produktes |
| GB2196830B (en) * | 1986-11-06 | 1990-08-29 | Gkn Vending Services Ltd | Storing pre-cooked food for vending |
| CN2084914U (zh) * | 1990-10-30 | 1991-09-18 | 中国医科大学附属第三医院 | 多功能变温贮血器 |
| US5891617A (en) * | 1993-09-15 | 1999-04-06 | Organogenesis Inc. | Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing |
| JP3037595B2 (ja) * | 1995-10-13 | 2000-04-24 | 岐阜プラスチック工業株式会社 | 運搬容器 |
| NL1004619C2 (nl) * | 1996-11-26 | 1998-05-27 | Instituut Voor Dierhouderij En | Inrichting en werkwijze voor het invriezen van levende cellen, in het bijzonder sperma. |
-
2002
- 2002-11-01 WO PCT/US2002/035135 patent/WO2003037082A1/en not_active Ceased
- 2002-11-01 DK DK02778703T patent/DK1441586T3/da active
- 2002-11-01 DE DE60212680T patent/DE60212680T2/de not_active Expired - Lifetime
- 2002-11-01 DE DE60211731T patent/DE60211731T2/de not_active Expired - Lifetime
- 2002-11-01 DK DK02778702T patent/DK1441585T3/da active
- 2002-11-01 JP JP2003539440A patent/JP2005507692A/ja active Pending
- 2002-11-01 EP EP02778703A patent/EP1441586B1/en not_active Expired - Lifetime
- 2002-11-01 CN CNB028218566A patent/CN1229018C/zh not_active Expired - Lifetime
- 2002-11-01 ES ES02778702T patent/ES2265057T3/es not_active Expired - Lifetime
- 2002-11-01 ES ES02778703T patent/ES2266588T3/es not_active Expired - Lifetime
- 2002-11-01 WO PCT/US2002/035137 patent/WO2003037083A1/en not_active Ceased
- 2002-11-01 AT AT02778702T patent/ATE326841T1/de not_active IP Right Cessation
- 2002-11-01 CN CNB028218582A patent/CN1242670C/zh not_active Expired - Fee Related
- 2002-11-01 EP EP02778702A patent/EP1441585B1/en not_active Expired - Lifetime
- 2002-11-01 JP JP2003539439A patent/JP2005523843A/ja active Pending
- 2002-11-01 CA CA002466130A patent/CA2466130A1/en not_active Abandoned
- 2002-11-01 CN CNB2005100978176A patent/CN1315374C/zh not_active Expired - Fee Related
- 2002-11-01 AT AT02778703T patent/ATE330466T1/de not_active IP Right Cessation
- 2002-11-01 CA CA002466122A patent/CA2466122A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007023907A1 (ja) * | 2005-08-24 | 2007-03-01 | Transcu Ltd. | 冷凍型イオントフォレーシス用電極構造体 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK1441585T3 (da) | 2006-10-02 |
| EP1441585A1 (en) | 2004-08-04 |
| WO2003037083A9 (en) | 2004-01-15 |
| EP1441586A1 (en) | 2004-08-04 |
| CN1732776A (zh) | 2006-02-15 |
| DK1441586T3 (da) | 2006-10-23 |
| JP2005523843A (ja) | 2005-08-11 |
| ATE330466T1 (de) | 2006-07-15 |
| HK1074749A1 (en) | 2005-11-25 |
| WO2003037082A1 (en) | 2003-05-08 |
| WO2003037083A1 (en) | 2003-05-08 |
| ES2265057T3 (es) | 2007-02-01 |
| WO2003037082A9 (en) | 2004-01-15 |
| DE60212680D1 (de) | 2006-08-03 |
| HK1087889A1 (en) | 2006-10-27 |
| ES2266588T3 (es) | 2007-03-01 |
| CA2466130A1 (en) | 2003-05-08 |
| DE60212680T2 (de) | 2007-06-28 |
| CN1242670C (zh) | 2006-02-22 |
| ATE326841T1 (de) | 2006-06-15 |
| CN1582111A (zh) | 2005-02-16 |
| CN1229018C (zh) | 2005-11-30 |
| EP1441586B1 (en) | 2006-06-21 |
| EP1441585B1 (en) | 2006-05-24 |
| DE60211731T2 (de) | 2007-05-16 |
| DE60211731D1 (de) | 2006-06-29 |
| HK1074748A1 (en) | 2005-11-25 |
| CA2466122A1 (en) | 2003-05-08 |
| CN1315374C (zh) | 2007-05-16 |
| CN1582112A (zh) | 2005-02-16 |
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