JP2005507362A5 - - Google Patents

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Publication number
JP2005507362A5
JP2005507362A5 JP2002562718A JP2002562718A JP2005507362A5 JP 2005507362 A5 JP2005507362 A5 JP 2005507362A5 JP 2002562718 A JP2002562718 A JP 2002562718A JP 2002562718 A JP2002562718 A JP 2002562718A JP 2005507362 A5 JP2005507362 A5 JP 2005507362A5
Authority
JP
Japan
Prior art keywords
amino
hydrogen
methyl
dichloro
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002562718A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005507362A (ja
Filing date
Publication date
Priority claimed from US09/777,217 external-priority patent/US6645968B2/en
Application filed filed Critical
Publication of JP2005507362A publication Critical patent/JP2005507362A/ja
Publication of JP2005507362A5 publication Critical patent/JP2005507362A5/ja
Pending legal-status Critical Current

Links

JP2002562718A 2001-02-05 2002-01-17 カリウムチャンネル開放剤 Pending JP2005507362A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/777,217 US6645968B2 (en) 1999-08-03 2001-02-05 Potassium channel openers
PCT/US2002/005252 WO2002062762A2 (en) 2001-02-05 2002-01-17 Potassium channel openers

Publications (2)

Publication Number Publication Date
JP2005507362A JP2005507362A (ja) 2005-03-17
JP2005507362A5 true JP2005507362A5 (enExample) 2005-06-09

Family

ID=27613828

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002562718A Pending JP2005507362A (ja) 2001-02-05 2002-01-17 カリウムチャンネル開放剤

Country Status (9)

Country Link
US (1) US6645968B2 (enExample)
EP (1) EP1392655B1 (enExample)
JP (1) JP2005507362A (enExample)
AT (1) ATE401310T1 (enExample)
CA (1) CA2437405A1 (enExample)
DE (1) DE60227662D1 (enExample)
ES (1) ES2311594T3 (enExample)
MX (1) MXPA03006969A (enExample)
WO (1) WO2002062762A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030097897A (ko) 2001-05-24 2003-12-31 레오 파마 에이/에스 신규한 피리딜 시아노구아니딘 화합물
JP4753523B2 (ja) * 2002-09-03 2011-08-24 株式会社明治 子宮平滑筋弛緩用の医療用の剤
ITTO20030668A1 (it) 2003-09-02 2005-03-03 Rotta Res Lab S P A O Ra Rottapharm Derivati dell'adamantano dotati di attivita' neuroprotettiva, antidepressiva e anti-ischemica e procedimento per la loro preparazione.
WO2006066584A1 (en) * 2004-12-22 2006-06-29 Leo Pharma A/S Novel cyanoguanidine compounds
WO2007015632A1 (en) * 2005-08-04 2007-02-08 Cgk Co., Ltd. Atm and atr inhibitor
WO2007022964A2 (de) * 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
JP5752239B2 (ja) 2010-05-14 2015-07-22 チャイニーズ・ピーエルエイ・ゼネラル・ホスピタル 尿素化合物及びアポトーシスを阻害するためのその使用
EP3085690B1 (en) * 2013-12-20 2019-09-11 Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China New urea compound, manufacturing method and application thereof
CN113683535B (zh) * 2020-05-18 2022-08-30 中国药科大学 含氰胍结构的化合物及其制备方法与用途
WO2022211810A1 (en) * 2021-03-31 2022-10-06 The Board Of Trustees Of The Leland Stanford Junior University Formulations for prolonging gestation and for complications of menstruation or gestation

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
FR1363904A (fr) * 1963-01-31 1964-06-19 Bruneau & Cie Lab Dérivés d'hexahydro pyrimidines et leur préparation
CH513913A (de) * 1968-01-18 1971-10-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen heterocyclischen, zweikernigen N,N'-Diglycidylverbindungen und ihre Verwendung
CH494771A (de) * 1968-01-18 1970-08-15 Ciba Geigy Verfahren zur Herstellung von neuen heterocyclischen, zweikernigen N,N'-Diglycidylverbindungen und ihre Verwendung
DE1912281C2 (de) * 1968-04-10 1983-03-24 CIBA-GEIGY AG, 4002 Basel Verfahren zur Herstellung von vorverlängerten, epoxidgruppenhaltigen Addukten aus Polyepoxidverbindungen und einkernigen difunktionellen N-heterocyclischen Verbindungen
CH500247A (de) * 1968-04-17 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen epoxidgruppenhaltigen Addukten aus Polyepoxidverbindungen und zweikernigen N-heterocyclischen Verbindungen
DE1810293A1 (de) 1968-11-22 1970-06-11 Bayer Ag N-Fluoracetylamino-methyl-harnstoffe und Verfahren zu ihrer Herstellung
GB1489879A (en) 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
US4146646A (en) 1976-02-12 1979-03-27 Fisons Limited Bis-amide fungicidal compounds
DE3027582A1 (de) * 1980-07-21 1982-02-25 Bayer Ag, 5090 Leverkusen Triazolidin-3,5-dion-formaldehyd-amin-kondensate und verfahren zu ihrer herstellung
US5654301A (en) 1985-02-15 1997-08-05 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5378729A (en) 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5278169A (en) 1988-08-09 1994-01-11 E. R. Squibb & Sons, Inc. Method of treating or prevention of fibrillation of the heart
US5028519A (en) * 1988-12-06 1991-07-02 Fuji Photo Film Co., Ltd. Silver halide color photosensitive material
NZ232336A (en) 1989-02-03 1991-07-26 Lilly Co Eli (-)-n"-cyano-n-3-pyridyl-n'-1,2,2 trimethylpropylguandine, salts thereof, pharmaceutical compositions and an intermediate (-)-n-3-pyridyl-n'-(1,2,2 trimethylpropyl)thiourea
US5140031A (en) 1989-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Pyranyl cyanoguanidine derivatives
CA2088195A1 (en) 1990-08-31 1992-03-01 David C. Horwell Cholecystokinin antagonists, their preparation and therapeutic use
JPH05294935A (ja) 1991-03-15 1993-11-09 Green Cross Corp:The アミノピリジン系化合物
JP3453741B2 (ja) 1993-07-08 2003-10-06 日本製紙株式会社 感熱記録体
US5547966A (en) 1993-10-07 1996-08-20 Bristol-Myers Squibb Company Aryl urea and related compounds
WO1997014417A1 (en) 1995-10-19 1997-04-24 Merck & Co., Inc. Fibrinogen receptor antagonists
JP2002505683A (ja) 1997-06-18 2002-02-19 シナプティック・ファーマスーティカル・コーポレーション 複素環置換されたピペリジン類及びその使用
US6121323A (en) 1997-12-03 2000-09-19 3M Innovative Properties Company Bishydroxyureas
WO1999032495A1 (en) 1997-12-19 1999-07-01 Novo Nordisk A/S Pyrido 1,2,4-thiadiazine derivatives, their preparation and use
ATE373642T1 (de) * 1999-08-03 2007-10-15 Abbott Lab Kalium kanalaktivatoren
JP2001328979A (ja) * 2000-03-15 2001-11-27 Toyama Chem Co Ltd イソインドロン誘導体の製造法

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