JP2005195485A5 - - Google Patents

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Publication number
JP2005195485A5
JP2005195485A5 JP2004002886A JP2004002886A JP2005195485A5 JP 2005195485 A5 JP2005195485 A5 JP 2005195485A5 JP 2004002886 A JP2004002886 A JP 2004002886A JP 2004002886 A JP2004002886 A JP 2004002886A JP 2005195485 A5 JP2005195485 A5 JP 2005195485A5
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JP
Japan
Prior art keywords
light source
confocal
semiconductor
excitation
fluorescence
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JP2004002886A
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English (en)
Japanese (ja)
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JP4414771B2 (ja
JP2005195485A (ja
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Priority to JP2004002886A priority Critical patent/JP4414771B2/ja
Priority claimed from JP2004002886A external-priority patent/JP4414771B2/ja
Priority to US11/020,456 priority patent/US7315039B2/en
Publication of JP2005195485A publication Critical patent/JP2005195485A/ja
Publication of JP2005195485A5 publication Critical patent/JP2005195485A5/ja
Application granted granted Critical
Publication of JP4414771B2 publication Critical patent/JP4414771B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004002886A 2004-01-08 2004-01-08 共焦点顕微分光装置 Expired - Fee Related JP4414771B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2004002886A JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置
US11/020,456 US7315039B2 (en) 2004-01-08 2004-12-22 Confocal microspectroscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004002886A JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置

Publications (3)

Publication Number Publication Date
JP2005195485A JP2005195485A (ja) 2005-07-21
JP2005195485A5 true JP2005195485A5 (cg-RX-API-DMAC10.html) 2007-02-22
JP4414771B2 JP4414771B2 (ja) 2010-02-10

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Family Applications (1)

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JP2004002886A Expired - Fee Related JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置

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US (1) US7315039B2 (cg-RX-API-DMAC10.html)
JP (1) JP4414771B2 (cg-RX-API-DMAC10.html)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60141090D1 (de) 2000-10-30 2010-03-04 Gen Hospital Corp Optische systeme zur gewebeanalyse
CA2519937C (en) 2003-03-31 2012-11-20 Guillermo J. Tearney Speckle reduction in optical coherence tomography by path length encoded angular compounding
KR101204370B1 (ko) 2003-06-06 2012-11-23 더 제너럴 하스피탈 코포레이션 파장 동조 소스용 방법 및 장치
JP4995720B2 (ja) 2004-07-02 2012-08-08 ザ ジェネラル ホスピタル コーポレイション ダブルクラッドファイバを有する内視鏡撮像プローブ
ATE538714T1 (de) 2004-08-24 2012-01-15 Gen Hospital Corp Verfahren, system und software-anordnung zur bestimmung des elastizitätsmoduls
JP5324095B2 (ja) 2004-08-24 2013-10-23 ザ ジェネラル ホスピタル コーポレイション 血管セグメントを画像化する方法および装置
EP1816949A1 (en) 2004-11-29 2007-08-15 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
US8351665B2 (en) 2005-04-28 2013-01-08 The General Hospital Corporation Systems, processes and software arrangements for evaluating information associated with an anatomical structure by an optical coherence ranging technique
EP1889037A2 (en) 2005-06-01 2008-02-20 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
EP1913332B1 (en) 2005-08-09 2010-10-13 The General Hospital Corporation Apparatus and method for performing polarization-based quadrature demodulation in optical coherence tomography
US20070121196A1 (en) 2005-09-29 2007-05-31 The General Hospital Corporation Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions
US7889348B2 (en) * 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
EP2289397A3 (en) 2006-01-19 2011-04-06 The General Hospital Corporation Methods and systems for optical imaging of epithelial luminal organs by beam scanning thereof
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
WO2007149602A2 (en) 2006-02-01 2007-12-27 The General Hospital Corporation Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
EP1986545A2 (en) 2006-02-01 2008-11-05 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
JP2007225381A (ja) * 2006-02-22 2007-09-06 Osaka Prefecture Univ 蛍光測定方法及び蛍光顕微鏡
WO2007101026A2 (en) 2006-02-24 2007-09-07 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
EP2015669A2 (en) 2006-05-10 2009-01-21 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
US7846391B2 (en) 2006-05-22 2010-12-07 Lumencor, Inc. Bioanalytical instrumentation using a light source subsystem
US8838213B2 (en) 2006-10-19 2014-09-16 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s)
DE102007003134A1 (de) * 2007-01-18 2008-07-24 Carl Zeiss Microimaging Gmbh Laserscanmikroskop und strahlvereinigende optische Baugruppe
US9176319B2 (en) 2007-03-23 2015-11-03 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US8098375B2 (en) 2007-08-06 2012-01-17 Lumencor, Inc. Light emitting diode illumination system
EP2309923B1 (en) 2008-07-14 2020-11-25 The General Hospital Corporation Apparatus and methods for color endoscopy
KR101018153B1 (ko) * 2008-11-27 2011-02-28 삼성엘이디 주식회사 Ｌｅｄ 패키지
JP5731394B2 (ja) 2008-12-10 2015-06-10 ザ ジェネラル ホスピタル コーポレイション 光サブサンプリングを通じて、光コヒーレンストモグラヒィーのイメージング深度範囲を伸ばすためのシステム、装置及び方法
US9615748B2 (en) 2009-01-20 2017-04-11 The General Hospital Corporation Endoscopic biopsy apparatus, system and method
US8242462B2 (en) * 2009-01-23 2012-08-14 Lumencor, Inc. Lighting design of high quality biomedical devices
WO2010091190A2 (en) 2009-02-04 2010-08-12 The General Hospital Corporation Apparatus and method for utilization of a high-speed optical wavelength tuning source
CN102469943A (zh) 2009-07-14 2012-05-23 通用医疗公司 用于测量脉管内流动和压力的设备、系统和方法
SMT202000624T1 (it) 2010-03-05 2021-01-05 Massachusetts Gen Hospital Apparecchio per fornire radiazione elettromagnetica a un campione
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
EP2575598A2 (en) 2010-05-25 2013-04-10 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
US10285568B2 (en) 2010-06-03 2019-05-14 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
WO2012058381A2 (en) 2010-10-27 2012-05-03 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
US8389957B2 (en) 2011-01-14 2013-03-05 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
US8466436B2 (en) 2011-01-14 2013-06-18 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
CN102175643B (zh) * 2011-03-18 2013-04-10 苏州晓松科技开发有限公司 激光物证勘查仪
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
TWI454735B (zh) * 2011-08-19 2014-10-01 Anmo Electronics Corp 手持式螢光顯微鏡
EP2769491A4 (en) 2011-10-18 2015-07-22 Gen Hospital Corp DEVICE AND METHOD FOR PRODUCING AND / OR PROVIDING RECIRCULATING OPTICAL DELAY (DE)
US9642515B2 (en) 2012-01-20 2017-05-09 Lumencor, Inc. Solid state continuous white light source
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
US11490797B2 (en) 2012-05-21 2022-11-08 The General Hospital Corporation Apparatus, device and method for capsule microscopy
US9217561B2 (en) 2012-06-15 2015-12-22 Lumencor, Inc. Solid state light source for photocuring
US9415550B2 (en) 2012-08-22 2016-08-16 The General Hospital Corporation System, method, and computer-accessible medium for fabrication miniature endoscope using soft lithography
US10101274B2 (en) 2012-12-05 2018-10-16 Genepoc Inc. Optical interrogation device
JP2014115121A (ja) * 2012-12-06 2014-06-26 Sony Corp 微小粒子分析装置及び微小粒子分析方法
WO2014117130A1 (en) 2013-01-28 2014-07-31 The General Hospital Corporation Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
US11179028B2 (en) 2013-02-01 2021-11-23 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
WO2014144709A2 (en) 2013-03-15 2014-09-18 The General Hospital Corporation Methods and systems for characterizing an object
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
US10117576B2 (en) 2013-07-19 2018-11-06 The General Hospital Corporation System, method and computer accessible medium for determining eye motion by imaging retina and providing feedback for acquisition of signals from the retina
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
WO2015013651A2 (en) 2013-07-26 2015-01-29 The General Hospital Corporation System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography
CN104089883B (zh) * 2013-12-17 2017-02-01 浙江工商大学 基于激光器阵列的检测装置及小黄鱼存储时间检测方法
CN104076001A (zh) * 2013-12-17 2014-10-01 浙江工商大学 基于激光器阵列的检测装置及大黄鱼存储时间检测方法
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
WO2016015052A1 (en) 2014-07-25 2016-01-28 The General Hospital Corporation Apparatus, devices and methods for in vivo imaging and diagnosis
LU92620B1 (de) * 2014-12-19 2016-06-20 Leica Microsystems Rastermikroskop
CN104597590B (zh) * 2014-12-30 2018-02-02 深圳先进技术研究院 一种超分辨荧光光谱成像显微镜
CN106990519B (zh) * 2017-05-12 2024-09-24 中国科学院苏州生物医学工程技术研究所 结构光照明显微成像系统
JP7256207B2 (ja) * 2018-04-20 2023-04-11 ザ プロクター アンド ギャンブル カンパニー 頭皮ケア剤の空間的イメージング
US11525967B1 (en) 2018-09-28 2022-12-13 Apple Inc. Photonics integrated circuit architecture
US11471389B2 (en) 2019-06-28 2022-10-18 The Procter & Gamble Company Enhanced stability of zinc pyrithione in oxidative environments, such as scalp sebaceous fluid
US11881678B1 (en) 2019-09-09 2024-01-23 Apple Inc. Photonics assembly with a photonics die stack
EP4182747B1 (en) 2020-07-20 2025-06-18 Apple Inc. Photonic integrated circuits with controlled collapse chip connections
WO2023283294A1 (en) * 2021-07-08 2023-01-12 Apple Inc. Light source modules for noise mitigation
US11914201B2 (en) 2021-09-23 2024-02-27 Apple Inc. Mechanisms that transfer light between layers of multi-chip photonic assemblies
US12111207B2 (en) 2022-09-23 2024-10-08 Apple Inc. Despeckling in optical measurement systems

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239178A (en) * 1990-11-10 1993-08-24 Carl Zeiss Optical device with an illuminating grid and detector grid arranged confocally to an object
JPH0894938A (ja) * 1994-09-21 1996-04-12 Sony Corp 共焦点顕微鏡並びに光記録再生装置
JP3816632B2 (ja) * 1997-05-14 2006-08-30 オリンパス株式会社 走査型顕微鏡
US6121603A (en) * 1997-12-01 2000-09-19 Hang; Zhijiang Optical confocal device having a common light directing means
US6355934B1 (en) * 1999-02-26 2002-03-12 Packard Biochip Technologies Imaging system for an optical scanner
US6181474B1 (en) * 1999-03-22 2001-01-30 Kovex Corporation Scanning confocal microscope with objective lens position tracking
JP2001185796A (ja) * 1999-12-27 2001-07-06 Hitachi Metals Ltd レーザ装置、その応用装置並びにその使用方法
US6423956B1 (en) * 2000-07-28 2002-07-23 Optical Biopsy Technologies Fiber-coupled, high-speed, integrated, angled-dual-axis confocal scanning microscopes employing vertical cross-section scanning
DE10038526B4 (de) 2000-08-08 2004-09-02 Carl Zeiss Jena Gmbh Verfahren und Anordnung zur Erfassung des wellenlängenabhängigen Verhaltens einer beleuchteten Probe
US6858852B2 (en) * 2000-08-08 2005-02-22 Carl Zeiss Jena Gmbh Method and apparatus for rapid change of fluorescence bands in the detection of dyes in fluorescence microscopy
US6987259B2 (en) * 2002-05-30 2006-01-17 Dmetrix, Inc. Imaging system with an integrated source and detector array
US20050053109A1 (en) * 2002-06-03 2005-03-10 Josh Hogan Integrated multiple wavelength system
DE10225838B4 (de) * 2002-06-11 2021-10-21 Leica Microsystems Cms Gmbh Verfahren zur Scanmikroskopie, Scanmikroskop und Vorrichtung zum Codieren eines Beleuchtungslichtstrahles
US6985224B2 (en) * 2003-03-14 2006-01-10 The United States Of America As Represented By The Secretary Of The Navy Light emitting diode (LED) array for excitation emission matrix (EEM) fluorescence spectroscopy
US7215468B2 (en) * 2003-07-29 2007-05-08 Olympus Corporation Confocal microscope

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