JP2004532023A5 - - Google Patents
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- Publication number
- JP2004532023A5 JP2004532023A5 JP2002579516A JP2002579516A JP2004532023A5 JP 2004532023 A5 JP2004532023 A5 JP 2004532023A5 JP 2002579516 A JP2002579516 A JP 2002579516A JP 2002579516 A JP2002579516 A JP 2002579516A JP 2004532023 A5 JP2004532023 A5 JP 2004532023A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- antigen
- protein
- nucleic acid
- flavivirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 56
- 102000036639 antigens Human genes 0.000 claims 56
- 108091007433 antigens Proteins 0.000 claims 56
- 108020004707 nucleic acids Proteins 0.000 claims 38
- 102000039446 nucleic acids Human genes 0.000 claims 38
- 150000007523 nucleic acids Chemical class 0.000 claims 38
- 101710204837 Envelope small membrane protein Proteins 0.000 claims 24
- 241000710831 Flavivirus Species 0.000 claims 24
- 101710145006 Lysis protein Proteins 0.000 claims 24
- 241000700605 Viruses Species 0.000 claims 23
- 241000710842 Japanese encephalitis virus Species 0.000 claims 19
- 101710085938 Matrix protein Proteins 0.000 claims 17
- 101710127721 Membrane protein Proteins 0.000 claims 17
- 208000001490 Dengue Diseases 0.000 claims 16
- 206010012310 Dengue fever Diseases 0.000 claims 16
- 208000025729 dengue disease Diseases 0.000 claims 16
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 13
- 238000013518 transcription Methods 0.000 claims 13
- 230000035897 transcription Effects 0.000 claims 13
- 241000710888 St. Louis encephalitis virus Species 0.000 claims 8
- 241000710886 West Nile virus Species 0.000 claims 8
- 241000710772 Yellow fever virus Species 0.000 claims 8
- 229940051021 yellow-fever virus Drugs 0.000 claims 8
- 230000002163 immunogen Effects 0.000 claims 6
- 206010054261 Flavivirus infection Diseases 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 230000009918 complex formation Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 241000725619 Dengue virus Species 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000003053 immunization Effects 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 206010041896 St. Louis Encephalitis Diseases 0.000 claims 1
- 101710172711 Structural protein Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000014621 translational initiation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/826,115 US7227011B2 (en) | 1998-06-04 | 2001-04-04 | Nucleic acid vaccines for prevention of flavivirus infection |
| PCT/US2002/010764 WO2002081754A1 (en) | 2001-04-04 | 2002-04-04 | Nucleic acid vaccines for prevention of flavivirus infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009192598A Division JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532023A JP2004532023A (ja) | 2004-10-21 |
| JP2004532023A5 true JP2004532023A5 (enExample) | 2008-01-10 |
| JP4448281B2 JP4448281B2 (ja) | 2010-04-07 |
Family
ID=25245753
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579516A Expired - Lifetime JP4448281B2 (ja) | 2001-04-04 | 2002-04-04 | フラビウイルス感染症の予防のための核酸ワクチン |
| JP2009192598A Expired - Fee Related JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009192598A Expired - Fee Related JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US7227011B2 (enExample) |
| EP (3) | EP1935991B1 (enExample) |
| JP (2) | JP4448281B2 (enExample) |
| KR (1) | KR100913984B1 (enExample) |
| CN (2) | CN101002936A (enExample) |
| BR (1) | BRPI0208301B8 (enExample) |
| CA (1) | CA2443323C (enExample) |
| MX (1) | MXPA03008838A (enExample) |
| NZ (1) | NZ529106A (enExample) |
| WO (1) | WO2002081754A1 (enExample) |
| ZA (1) | ZA200307580B (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| WO2001051500A1 (en) | 2000-01-14 | 2001-07-19 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| FR2823222B1 (fr) * | 2001-04-06 | 2004-02-06 | Merial Sas | Vaccin contre le virus de la fievre du nil |
| US7740863B2 (en) * | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| US20040037848A1 (en) * | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| US20050031641A1 (en) * | 2001-04-06 | 2005-02-10 | Loosmore Sheena May | Recombinant vaccine against West Nile Virus |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| ES2435095T3 (es) * | 2001-07-27 | 2013-12-18 | Zoetis W Llc | Vacuna del Nilo Occidental |
| US7354909B2 (en) * | 2001-08-14 | 2008-04-08 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| AU2002366710A1 (en) | 2001-12-20 | 2003-07-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| US7785799B2 (en) * | 2002-08-16 | 2010-08-31 | The Board Of Regents Of The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain III antigens |
| US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
| BR0315935A (pt) * | 2002-10-31 | 2005-09-20 | Health Research Inc | Teste de diagnóstico para o vìrus do nilo ocidental |
| DK1558276T3 (da) * | 2002-11-08 | 2012-10-22 | Univ Tulane | Flavivirus-fusionsinhibitorer |
| CA2432738A1 (en) * | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| US8475808B2 (en) | 2003-05-23 | 2013-07-02 | Novartis Vaccines And Diagnostics, Inc. | Immunogenic reagents from west nile virus |
| US7060280B2 (en) * | 2003-06-11 | 2006-06-13 | Academia Sinica | Immunization against flavivirus |
| US7585621B2 (en) | 2003-09-09 | 2009-09-08 | Idexx Laboratories, Inc. | Detection of West Nile virus infection and vaccination |
| US7074555B2 (en) | 2004-04-28 | 2006-07-11 | Idexx Laboratories, Inc. | Detection of West Nile Virus |
| US20080118528A1 (en) * | 2004-05-04 | 2008-05-22 | Tsanyang Jake Liang | Synthesis and Purification of West Nile Virus Virus-Like Particles |
| CN103088038B (zh) * | 2004-07-12 | 2015-06-24 | 美国天甲生物医药有限公司 | 黄病毒疫苗 |
| ATE521627T1 (de) | 2004-07-27 | 2011-09-15 | Us Gov Health & Human Serv | Identifikation kreuzreaktiver epitope des flavivirus-hüllglykoproteins |
| US7482017B2 (en) * | 2004-09-09 | 2009-01-27 | Research Development Foundation | Flavivirus variants having phenotypic variation and immunogenic compositions thereof |
| SG156666A1 (en) * | 2004-10-20 | 2009-11-26 | Acambis Inc | Vaccines against japanese encephalitis virus and west nile virus |
| EP1863528A2 (en) * | 2005-04-01 | 2007-12-12 | Wyeth | Use of wnv dna vaccine in combination with a conventional vaccine to overcome immunogen interference |
| IL308456A (en) | 2005-04-08 | 2024-01-01 | Wyeth Llc | A multivalent pneumomuroral protein-polysaccharide conjugate preparation |
| EP1896069B1 (en) * | 2005-06-24 | 2013-03-13 | Intervet International BV | Inactivated chimeric vaccines and related methods of use |
| US7455842B2 (en) * | 2005-12-05 | 2008-11-25 | University Of Kansas | Chimeric West Nile viruses and uses thereof |
| US20070190617A1 (en) * | 2006-02-13 | 2007-08-16 | Chang-Jer Wu | DNA vaccine for Japanese encephalitis virus |
| US20080044808A1 (en) * | 2006-08-15 | 2008-02-21 | Qian-Li Song | West nile virus antigen and assay |
| WO2008127307A2 (en) * | 2006-11-09 | 2008-10-23 | The United States Of America As Represented By The Secretary Of The Navy | Induction of an immune response against dengue virus using prime-boost approach |
| WO2008118013A2 (en) | 2007-03-23 | 2008-10-02 | To-Bbb Holding B.V. | Targeted intracellular delivery of antiviral agents |
| JP2008263964A (ja) * | 2007-03-29 | 2008-11-06 | Yamaguchi Univ | コウモリ由来細胞株 |
| EP2003144A1 (en) * | 2007-06-15 | 2008-12-17 | Institut Pasteur | Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications |
| WO2009024534A2 (en) * | 2007-08-17 | 2009-02-26 | Intercell Ag | Japanese encephalitis virus (jev) and tick-borne encephalitis virus (tbev) peptides stimulating human t cell responses |
| US8138318B2 (en) * | 2007-09-13 | 2012-03-20 | Abbott Laboratories | Hepatitis B pre-S2 nucleic acid |
| JP5788676B2 (ja) * | 2008-01-11 | 2015-10-07 | イノビオ ファーマシューティカルズ，インコーポレイティド | デングウイルスの複数のサブタイプに対する新規ワクチン |
| JP2011510672A (ja) * | 2008-02-08 | 2011-04-07 | インターツェル・アクチェンゲゼルシャフト | ワクチンとして使用するための、カプシドタンパク質中に欠失を含むフラビウイルス科突然変異体 |
| BRPI0910476A2 (pt) * | 2008-04-22 | 2018-03-27 | Cytios Biotechnology Ag | composições de vacinas para tratamento de febre do dengue e seus usos |
| CN101333246B (zh) * | 2008-07-30 | 2011-04-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒e蛋白中和性b细胞抗原表位多肽及其应用 |
| SG193821A1 (en) | 2008-08-29 | 2013-10-30 | Boehringer Ingelheim Vetmed | West nile virus vaccine |
| CN101607983B (zh) * | 2009-07-29 | 2012-06-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒PrM/M蛋白B细胞抗原表位多肽及应用 |
| ES2524975T3 (es) | 2009-07-31 | 2014-12-16 | Ge Healthcare Bio-Sciences Corp. | Cepa del virus de la fiebre amarilla de alto rendimiento con mayor propagación en células |
| US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
| CN102906266A (zh) | 2010-05-21 | 2013-01-30 | 高等教育联邦系统-匹兹堡大学 | 登革病毒通用序列及其使用方法 |
| AR079970A1 (es) * | 2010-07-23 | 2012-02-29 | Xcellerex Inc | Cepas de alto rendimiento del virus de la fiebre amarilla con una propagacion incrementada en las celulas |
| US20120294889A1 (en) * | 2010-11-12 | 2012-11-22 | Paxvax, Inc. | Chimeric Flavivirus Vaccines |
| AU2012229192B2 (en) | 2011-03-14 | 2017-04-20 | Boehringer Ingelheim Animal Health USA Inc. | Equine Rhinitis vaccine |
| EP3269728B1 (en) | 2011-10-20 | 2020-12-16 | The Government of The United States of America as represented by The Secretary, Department of Health and Human Services | Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes |
| US8920804B2 (en) | 2011-12-22 | 2014-12-30 | Inbios International, Inc. | Methods and materials for the detection of dengue virus infection |
| US20150265695A1 (en) * | 2012-07-24 | 2015-09-24 | Sanofi Pasteur | Vaccine compositions for prevention against dengue virus infection |
| TWI852899B (zh) | 2014-09-02 | 2024-08-21 | 法商賽諾菲巴斯德公司 | 疫苗組合物 |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| CN104630160B (zh) * | 2015-01-23 | 2018-04-27 | 中国农业科学院哈尔滨兽医研究所 | 表达西尼罗热病毒PrM/E蛋白的重组新城疫LaSota疫苗株 |
| EP3316905A1 (en) | 2015-07-03 | 2018-05-09 | Sanofi Pasteur | Concomitant dengue and yellow fever vaccination |
| MA42502A (fr) * | 2015-07-21 | 2018-05-30 | Modernatx Inc | Vaccins contre une maladie infectieuse |
| CA3026807A1 (en) * | 2016-06-13 | 2017-12-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays |
| US20180028643A1 (en) * | 2016-06-21 | 2018-02-01 | Brock Adam Kingstad-Bakke | Zika virus vaccines using virus-like particles |
| WO2018052549A1 (en) | 2016-09-19 | 2018-03-22 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
| EP3541416A1 (en) * | 2016-11-17 | 2019-09-25 | GlaxoSmithKline Biologicals SA | Zika viral antigen constructs |
| WO2018152526A1 (en) | 2017-02-20 | 2018-08-23 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
| JP7313345B2 (ja) | 2017-10-05 | 2023-07-24 | サノフィ・パスツール | デング熱に対するブースターワクチン接種のための組成物 |
| EP3530668A1 (en) * | 2018-02-22 | 2019-08-28 | Euroimmun Medizinische Labordiagnostika AG | A novel assay for the diagnosis of viral infections |
| EP3755709A1 (en) * | 2018-02-22 | 2020-12-30 | Euroimmun Medizinische Labordiagnostika AG | Assay for the diagnosis of viral infections |
| CN113583117B (zh) * | 2018-04-04 | 2022-04-15 | 中国科学院微生物研究所 | 一种高灵敏度的黄热病毒人源单克隆抗体及其应用 |
| CN108904793B (zh) * | 2018-07-29 | 2021-03-30 | 首都医科大学附属北京友谊医院 | 预防流行性乙型脑炎的dna疫苗及其构建方法 |
| US12576144B2 (en) * | 2018-12-20 | 2026-03-17 | The Wistar Institute Of Anatomy And Biology | Vaccines against Powassan virus, and methods of using same |
| US20250276051A1 (en) * | 2019-12-18 | 2025-09-04 | Geneone Life Science, Inc. | Powassan viral antigens and related compositions, and uses thereof to vaccinate and treat patients |
| KR102216078B1 (ko) * | 2020-04-22 | 2021-02-16 | 국방과학연구소 | 유전자 백신으로 사용하기 위한 항원 유전자 전달용 발현 벡터 및 이를 포함하는 유전자 백신 |
| WO2021262659A1 (en) * | 2020-06-22 | 2021-12-30 | University Of Connecticut | Flavivirus signal peptides, vaccine constructs, and methods therefor |
| US20260167703A1 (en) * | 2022-11-02 | 2026-06-18 | Takeda Vaccines, Inc. | A method for determining the infectivity of a virus |
Family Cites Families (33)
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|---|---|---|---|---|
| FR1601438A (enExample) | 1968-10-17 | 1970-08-24 | ||
| JPS53133627A (en) | 1977-04-25 | 1978-11-21 | Nippon Seibutsu Kagaku Kenkiyu | High purity deactivated vaccine for japanese encephalitis |
| JPH0768267B2 (ja) * | 1986-06-05 | 1995-07-26 | 財団法人阪大微生物病研究会 | フラビウイルス抗原 |
| JPS634895A (ja) | 1986-06-24 | 1988-01-09 | Mitsubishi Electric Corp | オゾン精製水供給装置 |
| JPS63105682A (ja) | 1986-10-23 | 1988-05-10 | Mitsubishi Kasei Corp | デングウイルス３型由来のｃＤＮＡ |
| FR2614219B1 (fr) | 1987-04-23 | 1993-07-09 | Materiels Annexes Dialyse | Procede de fabrication de granules destines a la preparation de solutions de dialyse et installation pour sa mise en oeuvre. |
| JPH084508B2 (ja) | 1987-09-16 | 1996-01-24 | 国立予防衛生研究所長 | 組み換えワクチニアウイルス |
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| IL91304A0 (en) | 1988-08-20 | 1990-03-19 | Us Health | Recombinant vaccinia virus for prevention of disease caused by flavivirus |
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| WO1999063095A1 (en) | 1998-06-04 | 1999-12-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nucleic acid vaccines for prevention of flavivirus infection |
| US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| US20050048073A1 (en) | 2001-02-28 | 2005-03-03 | De Groot Anne S. | Methods of determining west nile virus epitopes and method of using the same |
| US20030148261A1 (en) | 2001-03-12 | 2003-08-07 | Erol Fikrig | Compositions and methods comprising West Nile virus polypeptides |
-
2001
- 2001-04-04 US US09/826,115 patent/US7227011B2/en not_active Expired - Lifetime
-
2002
- 2002-04-04 MX MXPA03008838A patent/MXPA03008838A/es active IP Right Grant
- 2002-04-04 EP EP08004141A patent/EP1935991B1/en not_active Expired - Lifetime
- 2002-04-04 CN CNA2007100020999A patent/CN101002936A/zh active Pending
- 2002-04-04 NZ NZ529106A patent/NZ529106A/en not_active IP Right Cessation
- 2002-04-04 US US10/500,796 patent/US7662394B2/en not_active Expired - Lifetime
- 2002-04-04 KR KR1020037013021A patent/KR100913984B1/ko not_active Expired - Lifetime
- 2002-04-04 BR BRPI0208301-9 patent/BRPI0208301B8/pt not_active IP Right Cessation
- 2002-04-04 CN CNB02807758XA patent/CN1304575C/zh not_active Expired - Lifetime
- 2002-04-04 JP JP2002579516A patent/JP4448281B2/ja not_active Expired - Lifetime
- 2002-04-04 CA CA2443323A patent/CA2443323C/en not_active Expired - Lifetime
- 2002-04-04 EP EP02763960A patent/EP1383931A4/en not_active Withdrawn
- 2002-04-04 EP EP10177282.0A patent/EP2332572B1/en not_active Expired - Lifetime
- 2002-04-04 WO PCT/US2002/010764 patent/WO2002081754A1/en not_active Ceased
-
2003
- 2003-09-29 ZA ZA2003/07580A patent/ZA200307580B/en unknown
-
2006
- 2006-06-14 US US11/424,127 patent/US7521177B2/en not_active Expired - Fee Related
- 2006-06-14 US US11/424,138 patent/US7632510B2/en not_active Expired - Lifetime
-
2009
- 2009-07-24 US US12/508,946 patent/US8232379B2/en not_active Expired - Fee Related
- 2009-08-21 JP JP2009192598A patent/JP5236597B2/ja not_active Expired - Fee Related
- 2009-10-15 US US12/580,080 patent/US8221768B2/en not_active Expired - Fee Related
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