JP2004532023A5 - - Google Patents
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- Publication number
- JP2004532023A5 JP2004532023A5 JP2002579516A JP2002579516A JP2004532023A5 JP 2004532023 A5 JP2004532023 A5 JP 2004532023A5 JP 2002579516 A JP2002579516 A JP 2002579516A JP 2002579516 A JP2002579516 A JP 2002579516A JP 2004532023 A5 JP2004532023 A5 JP 2004532023A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- antigen
- protein
- nucleic acid
- flavivirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 56
- 102000036639 antigens Human genes 0.000 claims 56
- 108091007433 antigens Proteins 0.000 claims 56
- 108020004707 nucleic acids Proteins 0.000 claims 38
- 102000039446 nucleic acids Human genes 0.000 claims 38
- 150000007523 nucleic acids Chemical class 0.000 claims 38
- 101710204837 Envelope small membrane protein Proteins 0.000 claims 24
- 241000710831 Flavivirus Species 0.000 claims 24
- 101710145006 Lysis protein Proteins 0.000 claims 24
- 241000700605 Viruses Species 0.000 claims 23
- 241000710842 Japanese encephalitis virus Species 0.000 claims 19
- 101710085938 Matrix protein Proteins 0.000 claims 17
- 101710127721 Membrane protein Proteins 0.000 claims 17
- 208000001490 Dengue Diseases 0.000 claims 16
- 206010012310 Dengue fever Diseases 0.000 claims 16
- 208000025729 dengue disease Diseases 0.000 claims 16
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 13
- 238000013518 transcription Methods 0.000 claims 13
- 230000035897 transcription Effects 0.000 claims 13
- 241000710888 St. Louis encephalitis virus Species 0.000 claims 8
- 241000710886 West Nile virus Species 0.000 claims 8
- 241000710772 Yellow fever virus Species 0.000 claims 8
- 229940051021 yellow-fever virus Drugs 0.000 claims 8
- 230000002163 immunogen Effects 0.000 claims 6
- 206010054261 Flavivirus infection Diseases 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 230000009918 complex formation Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 241000725619 Dengue virus Species 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000003053 immunization Effects 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 206010041896 St. Louis Encephalitis Diseases 0.000 claims 1
- 101710172711 Structural protein Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000014621 translational initiation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/826,115 US7227011B2 (en) | 1998-06-04 | 2001-04-04 | Nucleic acid vaccines for prevention of flavivirus infection |
| PCT/US2002/010764 WO2002081754A1 (en) | 2001-04-04 | 2002-04-04 | Nucleic acid vaccines for prevention of flavivirus infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009192598A Division JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532023A JP2004532023A (ja) | 2004-10-21 |
| JP2004532023A5 true JP2004532023A5 (enExample) | 2008-01-10 |
| JP4448281B2 JP4448281B2 (ja) | 2010-04-07 |
Family
ID=25245753
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579516A Expired - Lifetime JP4448281B2 (ja) | 2001-04-04 | 2002-04-04 | フラビウイルス感染症の予防のための核酸ワクチン |
| JP2009192598A Expired - Fee Related JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009192598A Expired - Fee Related JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US7227011B2 (enExample) |
| EP (3) | EP2332572B1 (enExample) |
| JP (2) | JP4448281B2 (enExample) |
| KR (1) | KR100913984B1 (enExample) |
| CN (2) | CN1304575C (enExample) |
| BR (1) | BRPI0208301B8 (enExample) |
| CA (1) | CA2443323C (enExample) |
| MX (1) | MXPA03008838A (enExample) |
| NZ (1) | NZ529106A (enExample) |
| WO (1) | WO2002081754A1 (enExample) |
| ZA (1) | ZA200307580B (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| AU2001227889A1 (en) | 2000-01-14 | 2001-07-24 | The United States of America, represented by The Secretary, Department of Health & Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US20040037848A1 (en) * | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| US7740863B2 (en) * | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| US20050031641A1 (en) * | 2001-04-06 | 2005-02-10 | Loosmore Sheena May | Recombinant vaccine against West Nile Virus |
| FR2823222B1 (fr) * | 2001-04-06 | 2004-02-06 | Merial Sas | Vaccin contre le virus de la fievre du nil |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| PL212212B1 (pl) * | 2001-07-27 | 2012-08-31 | Wyeth Corp | Kompozycja szczepionki przeciwko zakażeniu wirusem Zachodniego Nilu, kompozycja końskiej szczepionki, szczepionka wirusa Zachodniego Nilu oraz zastosowania |
| US7354909B2 (en) * | 2001-08-14 | 2008-04-08 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| AU2002366710A1 (en) * | 2001-12-20 | 2003-07-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS |
| AU2003263853A1 (en) * | 2002-08-16 | 2004-03-03 | Board Of Regents The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain iii antigens |
| US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
| AU2003296921A1 (en) * | 2002-10-31 | 2004-05-25 | Health Research, Inc. | Diagnostic test for west nile virus |
| ES2390874T3 (es) * | 2002-11-08 | 2012-11-19 | The Administrators Of The Tulane Educational Fund | Inhibidores de fusión de flavivirus |
| CA2432738A1 (en) * | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| EP1626708B1 (en) | 2003-05-23 | 2017-11-29 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic reagents from west nile virus |
| US7060280B2 (en) * | 2003-06-11 | 2006-06-13 | Academia Sinica | Immunization against flavivirus |
| WO2005024427A2 (en) * | 2003-09-09 | 2005-03-17 | Idexx Laboratories, Inc. | Detection of west nile virus infection and vaccination |
| US7074555B2 (en) | 2004-04-28 | 2006-07-11 | Idexx Laboratories, Inc. | Detection of West Nile Virus |
| EP1742963A2 (en) * | 2004-05-04 | 2007-01-17 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Synthesis and purification of west nile virus virus-like particles |
| CN103088038B (zh) * | 2004-07-12 | 2015-06-24 | 美国天甲生物医药有限公司 | 黄病毒疫苗 |
| CA2576798C (en) | 2004-07-27 | 2014-09-09 | Gwong-Jen J. Chang | Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use |
| WO2006029300A2 (en) * | 2004-09-09 | 2006-03-16 | Research Development Foundation | Flavivirus variants having phenotypic variation and immunogenic compositions thereof |
| NZ584079A (en) * | 2004-10-20 | 2011-10-28 | Acambis Inc | Vaccines against japanese encephalitis virus and west nile virus |
| AU2006232865A1 (en) * | 2005-04-01 | 2006-10-12 | Wyeth | Use of WNV DNA vaccine in combination with a conventional vaccine to overcome immunogen interference |
| CN104815327A (zh) | 2005-04-08 | 2015-08-05 | 惠氏有限责任公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
| US8048429B2 (en) * | 2005-06-24 | 2011-11-01 | Intervet International B.V. | Inactivated chimeric flavivirus |
| US7455842B2 (en) * | 2005-12-05 | 2008-11-25 | University Of Kansas | Chimeric West Nile viruses and uses thereof |
| US20070190617A1 (en) * | 2006-02-13 | 2007-08-16 | Chang-Jer Wu | DNA vaccine for Japanese encephalitis virus |
| US20080044808A1 (en) * | 2006-08-15 | 2008-02-21 | Qian-Li Song | West nile virus antigen and assay |
| EP2462930B1 (en) * | 2006-11-09 | 2017-05-31 | The United States Of America As Represented By The Secretary Of The Navy | Induction of an immune response against dengue virus using prime-boost approach |
| DK2308514T3 (da) | 2007-03-23 | 2013-09-02 | To Bbb Holding B V | Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren |
| JP2008263964A (ja) * | 2007-03-29 | 2008-11-06 | Yamaguchi Univ | コウモリ由来細胞株 |
| EP2003144A1 (en) * | 2007-06-15 | 2008-12-17 | Institut Pasteur | Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications |
| WO2009024534A2 (en) * | 2007-08-17 | 2009-02-26 | Intercell Ag | Japanese encephalitis virus (jev) and tick-borne encephalitis virus (tbev) peptides stimulating human t cell responses |
| US8138318B2 (en) * | 2007-09-13 | 2012-03-20 | Abbott Laboratories | Hepatitis B pre-S2 nucleic acid |
| WO2009099716A1 (en) * | 2008-01-11 | 2009-08-13 | Vgx Pharmaceuticals, Inc. | Novel vaccines against multiple subtypes of dengue virus |
| US8715999B2 (en) * | 2008-02-08 | 2014-05-06 | Valneva Austria Gmbh | Flaviviridae mutants comprising a deletion in the capsid protein for use as vaccines |
| CA2721657A1 (en) * | 2008-04-22 | 2009-10-29 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| CN101333246B (zh) * | 2008-07-30 | 2011-04-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒e蛋白中和性b细胞抗原表位多肽及其应用 |
| BRPI0918897B1 (pt) | 2008-08-29 | 2021-06-15 | Boehringer Ingelheim Animal Health USA Inc. | Composição imunogênica e seus usos |
| CN101607983B (zh) * | 2009-07-29 | 2012-06-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒PrM/M蛋白B细胞抗原表位多肽及应用 |
| DK2459709T3 (en) | 2009-07-31 | 2014-12-01 | Ge Healthcare Bio Sciences | HIGH-REPLACED YELLOW FEBER VIRUS TREASURY WITH INCREASED CELL STORAGE |
| US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
| MX2012012681A (es) | 2010-05-21 | 2012-12-17 | Univ Pittsburgh | Secuencias del virus de dengue universales y metodos de uso. |
| AR079970A1 (es) * | 2010-07-23 | 2012-02-29 | Xcellerex Inc | Cepas de alto rendimiento del virus de la fiebre amarilla con una propagacion incrementada en las celulas |
| US20120294889A1 (en) * | 2010-11-12 | 2012-11-22 | Paxvax, Inc. | Chimeric Flavivirus Vaccines |
| MX350718B (es) | 2011-03-14 | 2017-09-14 | Boehringer Ingelheim Vetmedica Inc | Vacuna de rinitis equina. |
| US20140286983A1 (en) | 2011-10-20 | 2014-09-25 | The Government of the USA as represented by the Secretaryof the Dept. of Health and Human Services | Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes |
| US8920804B2 (en) | 2011-12-22 | 2014-12-30 | Inbios International, Inc. | Methods and materials for the detection of dengue virus infection |
| WO2014016362A1 (en) * | 2012-07-24 | 2014-01-30 | Sanofi Pasteur | Vaccine compositions for prevention against dengue virus infection |
| TWI852899B (zh) | 2014-09-02 | 2024-08-21 | 法商賽諾菲巴斯德公司 | 疫苗組合物 |
| EP3031923A1 (en) | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| CN104630160B (zh) * | 2015-01-23 | 2018-04-27 | 中国农业科学院哈尔滨兽医研究所 | 表达西尼罗热病毒PrM/E蛋白的重组新城疫LaSota疫苗株 |
| EP3316905A1 (en) | 2015-07-03 | 2018-05-09 | Sanofi Pasteur | Concomitant dengue and yellow fever vaccination |
| EP4218805A1 (en) * | 2015-07-21 | 2023-08-02 | ModernaTX, Inc. | Infectious disease vaccines |
| WO2017218339A1 (en) * | 2016-06-13 | 2017-12-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays |
| US20180028643A1 (en) * | 2016-06-21 | 2018-02-01 | Brock Adam Kingstad-Bakke | Zika virus vaccines using virus-like particles |
| US10898566B2 (en) | 2016-09-19 | 2021-01-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Zika virus vaccines |
| US11780885B2 (en) * | 2016-11-17 | 2023-10-10 | Glaxosmithkline Biologicals Sa | Zika viral antigen constructs |
| WO2018152526A1 (en) | 2017-02-20 | 2018-08-23 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
| JP7313345B2 (ja) | 2017-10-05 | 2023-07-24 | サノフィ・パスツール | デング熱に対するブースターワクチン接種のための組成物 |
| EP3755709A1 (en) * | 2018-02-22 | 2020-12-30 | Euroimmun Medizinische Labordiagnostika AG | Assay for the diagnosis of viral infections |
| EP3530668A1 (en) * | 2018-02-22 | 2019-08-28 | Euroimmun Medizinische Labordiagnostika AG | A novel assay for the diagnosis of viral infections |
| CN113372441B (zh) * | 2018-04-04 | 2023-03-10 | 中国科学院微生物研究所 | 一种高灵敏度的黄热病毒人源单克隆抗体及其应用 |
| CN108904793B (zh) * | 2018-07-29 | 2021-03-30 | 首都医科大学附属北京友谊医院 | 预防流行性乙型脑炎的dna疫苗及其构建方法 |
| US20220054620A1 (en) * | 2018-12-20 | 2022-02-24 | The Wistar Institute Of Anatomy And Biology | Vaccines against powassan virus, and methods of using same |
| CA3162377A1 (en) * | 2019-12-18 | 2021-06-24 | Joel MASLOW | Powassan viral antigens and related compositions, and uses thereof to vaccinate and treat patients |
| KR102216078B1 (ko) * | 2020-04-22 | 2021-02-16 | 국방과학연구소 | 유전자 백신으로 사용하기 위한 항원 유전자 전달용 발현 벡터 및 이를 포함하는 유전자 백신 |
| US20230272405A1 (en) * | 2020-06-22 | 2023-08-31 | University Of Connecticut | Flavivirus signal peptides, vaccine constructs, and methods therefor |
| EP4612495A1 (en) * | 2022-11-02 | 2025-09-10 | Takeda Vaccines, Inc. | A method for determining the infectivity of a virus |
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| FR1601438A (enExample) | 1968-10-17 | 1970-08-24 | ||
| JPS53133627A (en) | 1977-04-25 | 1978-11-21 | Nippon Seibutsu Kagaku Kenkiyu | High purity deactivated vaccine for japanese encephalitis |
| JPH0768267B2 (ja) * | 1986-06-05 | 1995-07-26 | 財団法人阪大微生物病研究会 | フラビウイルス抗原 |
| JPS634895A (ja) | 1986-06-24 | 1988-01-09 | Mitsubishi Electric Corp | オゾン精製水供給装置 |
| JPS63105682A (ja) | 1986-10-23 | 1988-05-10 | Mitsubishi Kasei Corp | デングウイルス３型由来のｃＤＮＡ |
| FR2614219B1 (fr) | 1987-04-23 | 1993-07-09 | Materiels Annexes Dialyse | Procede de fabrication de granules destines a la preparation de solutions de dialyse et installation pour sa mise en oeuvre. |
| JPH084508B2 (ja) * | 1987-09-16 | 1996-01-24 | 国立予防衛生研究所長 | 組み換えワクチニアウイルス |
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| AU778988B2 (en) | 1998-06-04 | 2004-12-23 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Nucleic acid vaccines for prevention of flavivirus infection |
| AU2002305028A1 (en) | 2001-02-28 | 2002-10-28 | Brown University Research Foundation | West nile virus epitopes and uses thereof |
| AU2002309508A1 (en) | 2001-03-12 | 2002-09-24 | L2 Diagnostics, Llc | Compositions and methods comprising west nile virus polypeptides |
-
2001
- 2001-04-04 US US09/826,115 patent/US7227011B2/en not_active Expired - Lifetime
-
2002
- 2002-04-04 BR BRPI0208301 patent/BRPI0208301B8/pt not_active IP Right Cessation
- 2002-04-04 KR KR1020037013021A patent/KR100913984B1/ko not_active Expired - Lifetime
- 2002-04-04 EP EP10177282.0A patent/EP2332572B1/en not_active Expired - Lifetime
- 2002-04-04 JP JP2002579516A patent/JP4448281B2/ja not_active Expired - Lifetime
- 2002-04-04 EP EP08004141A patent/EP1935991B1/en not_active Expired - Lifetime
- 2002-04-04 MX MXPA03008838A patent/MXPA03008838A/es active IP Right Grant
- 2002-04-04 EP EP02763960A patent/EP1383931A4/en not_active Withdrawn
- 2002-04-04 CN CNB02807758XA patent/CN1304575C/zh not_active Expired - Lifetime
- 2002-04-04 NZ NZ529106A patent/NZ529106A/en not_active IP Right Cessation
- 2002-04-04 CN CNA2007100020999A patent/CN101002936A/zh active Pending
- 2002-04-04 US US10/500,796 patent/US7662394B2/en not_active Expired - Lifetime
- 2002-04-04 CA CA2443323A patent/CA2443323C/en not_active Expired - Lifetime
- 2002-04-04 WO PCT/US2002/010764 patent/WO2002081754A1/en not_active Ceased
-
2003
- 2003-09-29 ZA ZA2003/07580A patent/ZA200307580B/en unknown
-
2006
- 2006-06-14 US US11/424,127 patent/US7521177B2/en not_active Expired - Fee Related
- 2006-06-14 US US11/424,138 patent/US7632510B2/en not_active Expired - Lifetime
-
2009
- 2009-07-24 US US12/508,946 patent/US8232379B2/en not_active Expired - Fee Related
- 2009-08-21 JP JP2009192598A patent/JP5236597B2/ja not_active Expired - Fee Related
- 2009-10-15 US US12/580,080 patent/US8221768B2/en not_active Expired - Fee Related
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