JP2004529890A5 - - Google Patents
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- Publication number
- JP2004529890A5 JP2004529890A5 JP2002569118A JP2002569118A JP2004529890A5 JP 2004529890 A5 JP2004529890 A5 JP 2004529890A5 JP 2002569118 A JP2002569118 A JP 2002569118A JP 2002569118 A JP2002569118 A JP 2002569118A JP 2004529890 A5 JP2004529890 A5 JP 2004529890A5
- Authority
- JP
- Japan
- Prior art keywords
- nicotine
- substrate layer
- layer
- skin
- methacrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000010410 layer Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 11
- 229920001577 copolymer Polymers 0.000 claims 8
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 7
- 229960002715 nicotine Drugs 0.000 claims 7
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- -1 aluminum ions Chemical class 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 239000012752 auxiliary agent Substances 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011241 protective layer Substances 0.000 claims 1
- 230000003014 reinforcing effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 231100000245 skin permeability Toxicity 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000010936 titanium Substances 0.000 claims 1
- 229910052719 titanium Inorganic materials 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10110391A DE10110391A1 (de) | 2001-03-03 | 2001-03-03 | Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff |
| PCT/EP2002/001728 WO2002069940A2 (de) | 2001-03-03 | 2002-02-19 | Hochflexibles transdermales therapeutisches system mit nikotin als wirkstoff |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529890A JP2004529890A (ja) | 2004-09-30 |
| JP2004529890A5 true JP2004529890A5 (enExample) | 2006-08-03 |
Family
ID=7676278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002569118A Pending JP2004529890A (ja) | 2001-03-03 | 2002-02-19 | 活性成分としてのニコチンを有する可撓性の著しい皮膚透過性治療系 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8226974B2 (enExample) |
| EP (1) | EP1372619B1 (enExample) |
| JP (1) | JP2004529890A (enExample) |
| KR (1) | KR100873257B1 (enExample) |
| CN (1) | CN1330305C (enExample) |
| AR (1) | AR035688A1 (enExample) |
| AU (1) | AU2002308289B2 (enExample) |
| BR (1) | BR0207738A (enExample) |
| CA (1) | CA2440012C (enExample) |
| CZ (1) | CZ20032379A3 (enExample) |
| DE (1) | DE10110391A1 (enExample) |
| ES (1) | ES2386886T3 (enExample) |
| HU (1) | HUP0303311A3 (enExample) |
| IL (2) | IL157692A0 (enExample) |
| MX (1) | MXPA03007903A (enExample) |
| NZ (1) | NZ527824A (enExample) |
| PL (1) | PL205582B1 (enExample) |
| RU (1) | RU2302856C2 (enExample) |
| TW (1) | TWI264312B (enExample) |
| WO (1) | WO2002069940A2 (enExample) |
| ZA (1) | ZA200306194B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1655772B (zh) * | 2002-05-28 | 2010-05-26 | 拉伯泰克技术研发有限公司 | 含有芬太尼的贴剂 |
| RU2351315C2 (ru) * | 2003-07-24 | 2009-04-10 | Смитклайн Бичам Корпорейшн | Пленки, растворяющиеся в полости рта |
| RU2263503C1 (ru) * | 2004-04-23 | 2005-11-10 | Каш Тенгиз | Способ получения препарата и препарат для трансдермального введения никотина |
| ITMI20041628A1 (it) | 2004-08-06 | 2004-11-06 | Bouty S P A | Sistema terapeutico a rilascio controllato per uso topico transdermico |
| DE102005010255A1 (de) * | 2005-03-07 | 2006-09-14 | Lts Lohmann Therapie-Systeme Ag | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| JP5000932B2 (ja) * | 2005-06-21 | 2012-08-15 | 日東電工株式会社 | ニコチン含有経皮吸収製剤 |
| IL177071A0 (en) * | 2005-08-01 | 2006-12-10 | Nitto Denko Corp | Method of preparing a nicotine transdermal preparation |
| EP1774964B1 (en) | 2005-10-13 | 2014-08-06 | Nitto Denko Corporation | Nicotine transdermal preparation and production method thereof |
| US20090246264A1 (en) * | 2005-12-08 | 2009-10-01 | Fertin Pharma | Transdermal Tobacco Alkaloid Patch |
| US20090169606A1 (en) * | 2005-12-08 | 2009-07-02 | Fertin Pharma | Low Flexural Strength Transdermal Tobacco Alkaloid Patch |
| DE102006026060B4 (de) * | 2006-01-12 | 2013-01-31 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme |
| DE102006054733A1 (de) * | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit |
| WO2008145119A1 (en) * | 2007-05-31 | 2008-12-04 | Fertin Pharma A/S | Transdermal tobacco alkaloid reservoir patch |
| KR101883410B1 (ko) * | 2011-04-22 | 2018-07-30 | 아이큐어 주식회사 | 경피 흡수 제제 및 그 제조방법 |
| FR2987561B1 (fr) * | 2012-03-02 | 2014-04-11 | Pf Medicament | Dispositif transdermique comprenant des micro-particules poreuses |
| EP3280371B1 (de) * | 2015-04-08 | 2019-06-05 | LTS Lohmann Therapie-Systeme AG | Elektrisch erwärmbares pflaster |
| CA3033570C (en) * | 2015-08-17 | 2022-12-06 | Sidmak Laboratories (India) Pvt. Ltd. | Topical film delivery system |
| DE102018220589A1 (de) * | 2018-11-29 | 2020-06-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales System mit Überpflaster und Ringsystem |
| DE102020112143B4 (de) | 2020-05-05 | 2022-03-17 | Lts Lohmann Therapie-Systeme Ag | Nicotin - Corona |
| US20220175812A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| US12441996B2 (en) | 2023-12-08 | 2025-10-14 | Battelle Memorial Institute | Use of DNA origami nanostructures for molecular information based data storage systems |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4278018A (en) * | 1979-11-16 | 1981-07-14 | Ncr Canada Ltd. - Ncr Canada Ltee | Printing means |
| JPS61251619A (ja) | 1985-04-30 | 1986-11-08 | Nitto Electric Ind Co Ltd | ニコチン含有テ−プ製剤 |
| US6139868A (en) * | 1986-08-28 | 2000-10-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| DE3629304A1 (de) | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung |
| DE3727232A1 (de) | 1987-08-14 | 1989-02-23 | Lohmann Therapie Syst Lts | Verfahren zur herstellung einer darreichungs- und/oder dosierungsform fuer arzneimittelwirkstoffe |
| US4943435A (en) | 1987-10-05 | 1990-07-24 | Pharmetrix Corporation | Prolonged activity nicotine patch |
| US4915950A (en) * | 1988-02-12 | 1990-04-10 | Cygnus Research Corporation | Printed transdermal drug delivery device |
| US5364630A (en) * | 1988-06-14 | 1994-11-15 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| DE3827561C1 (enExample) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| DE3843238C1 (enExample) * | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
| DE3908432A1 (de) * | 1989-03-14 | 1990-09-27 | Lohmann Therapie Syst Lts | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
| DK0484543T3 (da) * | 1990-04-24 | 1996-01-22 | Teijin Ltd | Plaster |
| CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
| JPH08502727A (ja) | 1992-08-25 | 1996-03-26 | シグナス セラピューティック システムズ | プリントされた経皮薬剤送達デバイス |
| JPH09505028A (ja) * | 1993-07-09 | 1997-05-20 | シグナス，インコーポレイテッド | 経皮的／経頬的にニコチン置換治療を提供する方法およびデバイス |
| DE4332094C2 (de) * | 1993-09-22 | 1995-09-07 | Lohmann Therapie Syst Lts | Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung |
| WO1995024172A1 (en) * | 1994-03-07 | 1995-09-14 | Theratech, Inc. | Drug-containing adhesive composite transdermal delivery device |
| DE4416927C1 (de) * | 1994-05-13 | 1995-08-31 | Lohmann Therapie Syst Lts | Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung |
| KR0155193B1 (ko) * | 1994-10-04 | 1998-10-15 | 신재인 | 중하중 취급 및 미끄럼 방지용 전방향 바퀴 |
| FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
| DE19653606A1 (de) * | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
| DE19653605C2 (de) * | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| DE19826592A1 (de) * | 1998-06-15 | 1999-12-16 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung eines aus einzelnen Schichten bestehenden Laminats |
| EP1137406B2 (en) | 1998-12-07 | 2008-01-23 | J. Dev Limited | Transdermal patch for delivering volatile liquid drugs |
| DE19918106A1 (de) * | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
-
2001
- 2001-03-03 DE DE10110391A patent/DE10110391A1/de not_active Ceased
-
2002
- 2002-02-19 NZ NZ527824A patent/NZ527824A/en not_active IP Right Cessation
- 2002-02-19 EP EP02748317A patent/EP1372619B1/de not_active Expired - Lifetime
- 2002-02-19 BR BR0207738-8A patent/BR0207738A/pt not_active Application Discontinuation
- 2002-02-19 JP JP2002569118A patent/JP2004529890A/ja active Pending
- 2002-02-19 IL IL15769202A patent/IL157692A0/xx unknown
- 2002-02-19 HU HU0303311A patent/HUP0303311A3/hu unknown
- 2002-02-19 PL PL363697A patent/PL205582B1/pl unknown
- 2002-02-19 CA CA2440012A patent/CA2440012C/en not_active Expired - Lifetime
- 2002-02-19 US US10/469,163 patent/US8226974B2/en not_active Expired - Fee Related
- 2002-02-19 CZ CZ20032379A patent/CZ20032379A3/cs unknown
- 2002-02-19 CN CNB028059018A patent/CN1330305C/zh not_active Expired - Fee Related
- 2002-02-19 WO PCT/EP2002/001728 patent/WO2002069940A2/de not_active Ceased
- 2002-02-19 AU AU2002308289A patent/AU2002308289B2/en not_active Ceased
- 2002-02-19 RU RU2003129636/15A patent/RU2302856C2/ru active
- 2002-02-19 ES ES02748317T patent/ES2386886T3/es not_active Expired - Lifetime
- 2002-02-19 MX MXPA03007903A patent/MXPA03007903A/es active IP Right Grant
- 2002-02-19 KR KR1020037011540A patent/KR100873257B1/ko not_active Expired - Fee Related
- 2002-02-28 AR ARP020100725A patent/AR035688A1/es unknown
- 2002-03-01 TW TW091103842A patent/TWI264312B/zh not_active IP Right Cessation
-
2003
- 2003-08-11 ZA ZA200306194A patent/ZA200306194B/en unknown
- 2003-09-01 IL IL157692A patent/IL157692A/en not_active IP Right Cessation
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