JP2004529884A5 - - Google Patents

Download PDF

Info

Publication number
JP2004529884A5
JP2004529884A5 JP2002567231A JP2002567231A JP2004529884A5 JP 2004529884 A5 JP2004529884 A5 JP 2004529884A5 JP 2002567231 A JP2002567231 A JP 2002567231A JP 2002567231 A JP2002567231 A JP 2002567231A JP 2004529884 A5 JP2004529884 A5 JP 2004529884A5
Authority
JP
Japan
Prior art keywords
radiopharmaceutical composition
formula
substituted
radiopharmaceutical
biomolecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002567231A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004529884A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/005155 external-priority patent/WO2002067859A2/en
Publication of JP2004529884A publication Critical patent/JP2004529884A/ja
Publication of JP2004529884A5 publication Critical patent/JP2004529884A5/ja
Pending legal-status Critical Current

Links

JP2002567231A 2001-02-26 2002-02-22 金属放射性医薬のためのアスコルビン酸類似体 Pending JP2004529884A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27138901P 2001-02-26 2001-02-26
PCT/US2002/005155 WO2002067859A2 (en) 2001-02-26 2002-02-22 Ascorbic acid analogs for metalloradiopharmaceuticals

Publications (2)

Publication Number Publication Date
JP2004529884A JP2004529884A (ja) 2004-09-30
JP2004529884A5 true JP2004529884A5 (enExample) 2005-12-22

Family

ID=23035343

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002567231A Pending JP2004529884A (ja) 2001-02-26 2002-02-22 金属放射性医薬のためのアスコルビン酸類似体

Country Status (12)

Country Link
US (1) US6713042B2 (enExample)
EP (1) EP1365813A4 (enExample)
JP (1) JP2004529884A (enExample)
CN (1) CN1503680A (enExample)
AU (1) AU2002253999A1 (enExample)
BR (1) BR0207315A (enExample)
CA (1) CA2438204A1 (enExample)
CZ (1) CZ20032597A3 (enExample)
HU (1) HUP0304083A2 (enExample)
IL (1) IL157359A0 (enExample)
MX (1) MXPA03007595A (enExample)
WO (1) WO2002067859A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089470A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
WO2006020779A2 (en) * 2004-08-10 2006-02-23 Dow Global Technologies Inc. Targeting chelants and chelates
GB0427392D0 (en) * 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
RU2008150377A (ru) * 2006-05-19 2010-06-27 Нихон Меди-Физикс Ко., Лтд. (Jp) Новое соединение, обладающее сродством к амилоиду
AU2007262786B2 (en) * 2006-06-21 2012-12-06 Ge Healthcare Limited Radiopharmaceutical products
KR20090025282A (ko) * 2006-06-21 2009-03-10 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
EP2080526A4 (en) * 2006-11-09 2012-11-07 Nihon Mediphysics Co Ltd RADIOACTIVE DIAGNOSTIC IMAGING DAY
US20090252680A1 (en) * 2006-11-17 2009-10-08 Nihon- Medi-Physics Co., Ltd Novel compound with affinity for amyloid
CN101595108A (zh) * 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
KR101497406B1 (ko) * 2006-12-21 2015-03-02 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
CN101636183B (zh) 2007-02-13 2014-03-19 日本医事物理股份有限公司 放射性诊断显像剂的制备方法
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
CN101903381A (zh) * 2007-10-24 2010-12-01 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物
CN101909657A (zh) * 2007-10-30 2010-12-08 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物的应用及制备方法
AU2008319986A1 (en) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. Use of novel compound having affinity for amyloid, and process for production of the same
WO2009073698A1 (en) * 2007-12-04 2009-06-11 Bracco Imaging S.P.A. Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
EP2328411A1 (en) * 2008-09-05 2011-06-08 Molecular Insight Pharmaceuticals, Inc. Pharmaceutical composition of a radioiodinated benzamide derivative and methods of making the same
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
DK2419096T3 (da) 2009-04-15 2020-02-03 Lantheus Medical Imaging Inc Stabilisering af radiofarmaceutiske sammensætninger under anvendelse af ascorbinsyre
US9321095B2 (en) 2010-06-30 2016-04-26 General Electric Company Apparatuses and methods for cutting porous substrates
WO2013093099A1 (en) * 2011-12-22 2013-06-27 Piramal Imaging Sa Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof
CN104470547B (zh) * 2012-05-24 2018-01-26 未来化学株式会社 利用筒状物合成放射性药物的方法
US20140147381A1 (en) * 2012-11-29 2014-05-29 Gregory David Espenan 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment
WO2014126902A1 (en) * 2013-02-15 2014-08-21 Thomas Jefferson University Kit for tumor imaging
JP6500105B2 (ja) * 2014-11-27 2019-04-10 セルトリオン・インコーポレイテッド ペプチドが結合された安定したアスコルビン酸誘導体、その製造方法、及びそれを含む化粧料組成物
TWI604853B (zh) * 2016-05-03 2017-11-11 行政院原子能委員會核能研究所 放射免疫複合體、診療劑及套組
CN107167540B (zh) * 2017-07-08 2019-07-30 万舒（北京）医药科技有限公司 测定人尿液生物样品中的DTPA-Zn的方法
KR102207372B1 (ko) * 2020-03-31 2021-01-27 재단법인 아산사회복지재단 방사성 의약품의 안정화제 및 이를 포함하는 방사성 의약 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL42204A (en) * 1972-05-08 1976-09-30 Solco Basel Ag Process and apparatus for the manufacture of injectable radionuclide preparations
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
DK0422713T3 (da) * 1989-10-09 1995-04-10 Unilever Plc Spiseligt smøremateriale
DE69231469T2 (de) * 1991-08-29 2001-01-25 Mallinckrodt Medical, Inc. Verwendung von gentisinsäure oder gentisylalkohol zur stabilisierung von radio-markierten peptiden und proteinen
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
WO1997028181A2 (en) * 1996-02-02 1997-08-07 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US6066309A (en) * 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
US20020122768A1 (en) * 2000-07-06 2002-09-05 Shuang Liu Stable radiopharmaceutical compositions and methods for preparation thereof

Similar Documents

Publication Publication Date Title
JP2004529884A5 (enExample)
JP7650938B2 (ja) 鉛またはトリウム放射性核種に連結されたｐｓｍａ標的化化合物を含む錯体
JP3054346B2 (ja) ペプチド類
JP2007297404A (ja) 腫瘍造影剤としてのヌクレオチドポリリン酸に結合された放射性核種
DE69837038T2 (de) Tetraaza- oder n2s2-komplexanten, und deren verwendung in der radiodiagnostik oder radiotherapie
AU691806B2 (en) Chelating agents of the type XN1S1O1 for radioactive isotopes, metal complexes thereof, and their use in diagnosis and therapy
US20080260636A1 (en) Stabilization of radionuclide-containing compositions
KR100845449B1 (ko) 테크네튬-99ｍ 니트리드 이종복합체를 함유하는영상진단용 방사선 의약품
DE19860289C2 (de) Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium
EP0630264A1 (en) Ligands for improving metal chelate formation kinetics
US5961954A (en) Chealators of type XN1 S1 X1 for radioactive isotopes, their metal complexes and their diagnostic and therapeutical uses
KR102548998B1 (ko) 혈전영상을 위한 방사성의약품 및 조성물
US6143275A (en) Type S3 N2 chelators for radioactive isotopes, their metal complexes and their diagnostic and therapeutical use
HU221882B1 (hu) Komplexvegyületek véredénybetegségek diagnózisához
US5633372A (en) Heterocycle based nitrogen sulfur ligands useful in radiographic imaging agents
JPH11509224A (ja) 遷移金属窒化物錯体を含有し迅速な心筋クリアランスを有する心臓向性放射性製剤
JPS6087228A (ja) 心臓像形成用組成物
PL147612B1 (en) Method of obtaining a pharmaceutic with affinity to neoplastic tissues
JPH11505852A (ja) 隔離された画像診断剤