MXPA03007595A - Analogos de acido ascorbico para metalorradiofarmaceuticos. - Google Patents

Analogos de acido ascorbico para metalorradiofarmaceuticos.

Info

Publication number
MXPA03007595A
MXPA03007595A MXPA03007595A MXPA03007595A MXPA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A
Authority
MX
Mexico
Prior art keywords
metalloradiopharmaceuticals
ascorbic acid
acid analogs
analogs
ascorbic
Prior art date
Application number
MXPA03007595A
Other languages
English (en)
Spanish (es)
Inventor
Shuang Liu
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of MXPA03007595A publication Critical patent/MXPA03007595A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MXPA03007595A 2001-02-26 2002-02-22 Analogos de acido ascorbico para metalorradiofarmaceuticos. MXPA03007595A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27138901P 2001-02-26 2001-02-26
PCT/US2002/005155 WO2002067859A2 (en) 2001-02-26 2002-02-22 Ascorbic acid analogs for metalloradiopharmaceuticals

Publications (1)

Publication Number Publication Date
MXPA03007595A true MXPA03007595A (es) 2003-12-04

Family

ID=23035343

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007595A MXPA03007595A (es) 2001-02-26 2002-02-22 Analogos de acido ascorbico para metalorradiofarmaceuticos.

Country Status (12)

Country Link
US (1) US6713042B2 (enExample)
EP (1) EP1365813A4 (enExample)
JP (1) JP2004529884A (enExample)
CN (1) CN1503680A (enExample)
AU (1) AU2002253999A1 (enExample)
BR (1) BR0207315A (enExample)
CA (1) CA2438204A1 (enExample)
CZ (1) CZ20032597A3 (enExample)
HU (1) HUP0304083A2 (enExample)
IL (1) IL157359A0 (enExample)
MX (1) MXPA03007595A (enExample)
WO (1) WO2002067859A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
US20050089470A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
GB0427392D0 (en) * 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
EP2019103B1 (en) * 2006-05-19 2011-11-30 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
KR20090025282A (ko) * 2006-06-21 2009-03-10 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
CA2654369C (en) * 2006-06-21 2014-10-14 Ge Healthcare Limited Radiopharmaceutical products
EP2080526A4 (en) * 2006-11-09 2012-11-07 Nihon Mediphysics Co Ltd RADIOACTIVE DIAGNOSTIC IMAGING DAY
CA2669522A1 (en) * 2006-11-17 2008-05-22 Nihon Medi-Physics Co., Ltd. Novel compounds with affinity for amyloid
KR20090083414A (ko) * 2006-11-30 2009-08-03 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
RU2445120C2 (ru) * 2006-12-21 2012-03-20 Нихон Меди-Физикс Ко., Лтд. Радиоактивный агент для диагностической визуализации
CA2678020C (en) 2007-02-13 2015-03-24 Nihon Medi-Physics Co., Ltd. Method for production of radiation diagnostic imaging agent
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
US20100267952A1 (en) * 2007-10-30 2010-10-21 Nihon Medi-Physics Co., Ltd. Use of novel compound having affinity for amyloid, and process for production of the same
KR20100101576A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법
WO2009073698A1 (en) * 2007-12-04 2009-06-11 Bracco Imaging S.P.A. Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
CN102202503A (zh) * 2008-09-05 2011-09-28 分子制药洞察公司 放射性碘化苯甲酰胺衍生物的药用组合物及其制备方法
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
DK2419096T3 (da) * 2009-04-15 2020-02-03 Lantheus Medical Imaging Inc Stabilisering af radiofarmaceutiske sammensætninger under anvendelse af ascorbinsyre
US9321095B2 (en) 2010-06-30 2016-04-26 General Electric Company Apparatuses and methods for cutting porous substrates
WO2013093099A1 (en) * 2011-12-22 2013-06-27 Piramal Imaging Sa Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof
WO2013176522A1 (ko) * 2012-05-24 2013-11-28 서강대학교산학협력단 카트리지를 이용한 방사성의약품 제조방법
US20140147381A1 (en) * 2012-11-29 2014-05-29 Gregory David Espenan 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment
JP2016510342A (ja) * 2013-02-15 2016-04-07 トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ 腫瘍画像化のためのキット
ES2767412T3 (es) * 2014-11-27 2020-06-17 Celltrion Inc Derivado estable de ácido ascórbico conjugado con péptido, método de preparación del mismo y composición cosmética que comprende el mismo
TWI604853B (zh) * 2016-05-03 2017-11-11 行政院原子能委員會核能研究所 放射免疫複合體、診療劑及套組
CN107167540B (zh) * 2017-07-08 2019-07-30 万舒（北京）医药科技有限公司 测定人尿液生物样品中的DTPA-Zn的方法
KR102207372B1 (ko) * 2020-03-31 2021-01-27 재단법인 아산사회복지재단 방사성 의약품의 안정화제 및 이를 포함하는 방사성 의약 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5527973A (en) * 1972-05-08 1974-11-07 Solco Basel Ag PROCESS FORTHE MANUFACTURE OF INJECTABLE PREPARATIONS OF Tc99m AND/OR In113m AND APPARATUS FOR CARRYING OUT THE PROCESS
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
EP0422714A3 (en) * 1989-10-09 1991-09-25 Unilever Nv Edible fat composition
DE69231469T2 (de) * 1991-08-29 2001-01-25 Mallinckrodt Medical, Inc. Verwendung von gentisinsäure oder gentisylalkohol zur stabilisierung von radio-markierten peptiden und proteinen
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US6066309A (en) 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
AU2526497A (en) * 1996-02-02 1997-08-22 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
AU2002218751A1 (en) * 2000-07-06 2002-01-21 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions

Also Published As

Publication number Publication date
AU2002253999A1 (en) 2002-09-12
BR0207315A (pt) 2004-02-10
EP1365813A4 (en) 2006-03-22
WO2002067859A3 (en) 2002-11-28
US20020122769A1 (en) 2002-09-05
CA2438204A1 (en) 2002-09-06
JP2004529884A (ja) 2004-09-30
US6713042B2 (en) 2004-03-30
WO2002067859A2 (en) 2002-09-06
CZ20032597A3 (cs) 2004-12-15
EP1365813A2 (en) 2003-12-03
IL157359A0 (en) 2004-02-19
HUP0304083A2 (hu) 2004-03-29
CN1503680A (zh) 2004-06-09

Similar Documents

Publication Publication Date Title
MXPA03007595A (es) Analogos de acido ascorbico para metalorradiofarmaceuticos.
MXPA03009558A (es) Compuestos novedosos.
MXPA03005081A (es) Elevador.
ZA200308340B (en) Inhalation capsules.
MXPA03006268A (es) Compuestos terapeuticos de cromano.
ZA200208561B (en) Hydraulischer druckverstarker.
AU2002360487A8 (en) Acyclovir-peptide analogs
MXPA03006261A (es) Compuestos terapeuticos de cromano.
EG23387A (en) Spirocyclic 3-phenyl-3-substituted 4-ketolactams and-lactones.
ZA200110487B (en) Vitamin D3 Analogs.
GB0206189D0 (en) None available at present time
MXPA03008140A (es) Amidas de acido benzofuran-2-carboxilico sustituidas.
AU6807501A (en) 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
MXPA03005302A (es) Solucion acuosa para remover pintura.
MXPA03008139A (es) Fluoralcoxifenilsulfonilureas sustituidas.
GB0129988D0 (en) Imidazolidineacetic acid derivatives
PL366980A1 (en) Hydroxyeicosenoic acid analogs
MXPA03008394A (es) Derivados de biuretano.
PL358585A1 (en) N-substituted-1-amino-1,1-dialkylcarboxylic acid derivatives
GB0206188D0 (en) None available at present time
MXPA03004242A (es) Nuevas fenilpiperazinas.
ZA200200597B (en) Combination theraphy.
HUP0201095A3 (en) Last term for wire-chase
GB2377619B (en) Stiffener for caps
ZA200205115B (en) Novel cyclic compounds.

Legal Events

Date Code Title Description
FG Grant or registration