JP2004529884A - 金属放射性医薬のためのアスコルビン酸類似体 - Google Patents
金属放射性医薬のためのアスコルビン酸類似体 Download PDFInfo
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- JP2004529884A JP2004529884A JP2002567231A JP2002567231A JP2004529884A JP 2004529884 A JP2004529884 A JP 2004529884A JP 2002567231 A JP2002567231 A JP 2002567231A JP 2002567231 A JP2002567231 A JP 2002567231A JP 2004529884 A JP2004529884 A JP 2004529884A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/121—Solutions, i.e. homogeneous liquid formulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
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- Physics & Mathematics (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27138901P | 2001-02-26 | 2001-02-26 | |
| PCT/US2002/005155 WO2002067859A2 (en) | 2001-02-26 | 2002-02-22 | Ascorbic acid analogs for metalloradiopharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529884A true JP2004529884A (ja) | 2004-09-30 |
| JP2004529884A5 JP2004529884A5 (enExample) | 2005-12-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567231A Pending JP2004529884A (ja) | 2001-02-26 | 2002-02-22 | 金属放射性医薬のためのアスコルビン酸類似体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6713042B2 (enExample) |
| EP (1) | EP1365813A4 (enExample) |
| JP (1) | JP2004529884A (enExample) |
| CN (1) | CN1503680A (enExample) |
| AU (1) | AU2002253999A1 (enExample) |
| BR (1) | BR0207315A (enExample) |
| CA (1) | CA2438204A1 (enExample) |
| CZ (1) | CZ20032597A3 (enExample) |
| HU (1) | HUP0304083A2 (enExample) |
| IL (1) | IL157359A0 (enExample) |
| MX (1) | MXPA03007595A (enExample) |
| WO (1) | WO2002067859A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008056481A1 (en) * | 2006-11-09 | 2008-05-15 | Nihon Medi-Physics Co., Ltd. | Radioactive diagnostic imaging agent |
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| US20090252680A1 (en) * | 2006-11-17 | 2009-10-08 | Nihon- Medi-Physics Co., Ltd | Novel compound with affinity for amyloid |
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| KR101497406B1 (ko) * | 2006-12-21 | 2015-03-02 | 니혼 메디피직스 가부시키가이샤 | 방사성 화상 진단제 |
| CN101636183B (zh) | 2007-02-13 | 2014-03-19 | 日本医事物理股份有限公司 | 放射性诊断显像剂的制备方法 |
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| CN101909657A (zh) * | 2007-10-30 | 2010-12-08 | 日本医事物理股份有限公司 | 对淀粉样蛋白具有亲和性的新化合物的应用及制备方法 |
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| CN107167540B (zh) * | 2017-07-08 | 2019-07-30 | 万舒（北京）医药科技有限公司 | 测定人尿液生物样品中的DTPA-Zn的方法 |
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| US4504462A (en) * | 1982-06-10 | 1985-03-12 | Mallinckrodt, Inc. | Process for making a lyophilized product for use in skeletal imaging |
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| DE69231469T2 (de) * | 1991-08-29 | 2001-01-25 | Mallinckrodt Medical, Inc. | Verwendung von gentisinsäure oder gentisylalkohol zur stabilisierung von radio-markierten peptiden und proteinen |
| GB9417873D0 (en) * | 1994-09-06 | 1994-10-26 | Sandoz Ltd | Organic compounds |
| WO1997028181A2 (en) * | 1996-02-02 | 1997-08-07 | Rhomed Incorporated | Post-labeling stabilization of radiolabeled proteins and peptides |
| US6066309A (en) * | 1996-02-02 | 2000-05-23 | Rhomed Incorporated | Post-labeling stabilization of radiolabeled proteins and peptides |
| US5961955A (en) * | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
| US20020122768A1 (en) * | 2000-07-06 | 2002-09-05 | Shuang Liu | Stable radiopharmaceutical compositions and methods for preparation thereof |
-
2002
- 2002-02-22 EP EP02723206A patent/EP1365813A4/en not_active Withdrawn
- 2002-02-22 US US10/081,258 patent/US6713042B2/en not_active Expired - Fee Related
- 2002-02-22 CA CA002438204A patent/CA2438204A1/en not_active Abandoned
- 2002-02-22 CN CNA028087186A patent/CN1503680A/zh active Pending
- 2002-02-22 JP JP2002567231A patent/JP2004529884A/ja active Pending
- 2002-02-22 AU AU2002253999A patent/AU2002253999A1/en not_active Abandoned
- 2002-02-22 HU HU0304083A patent/HUP0304083A2/hu unknown
- 2002-02-22 CZ CZ20032597A patent/CZ20032597A3/cs unknown
- 2002-02-22 BR BR0207315-3A patent/BR0207315A/pt not_active IP Right Cessation
- 2002-02-22 IL IL15735902A patent/IL157359A0/xx unknown
- 2002-02-22 WO PCT/US2002/005155 patent/WO2002067859A2/en not_active Ceased
- 2002-02-22 MX MXPA03007595A patent/MXPA03007595A/es active IP Right Grant
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008056481A1 (en) * | 2006-11-09 | 2008-05-15 | Nihon Medi-Physics Co., Ltd. | Radioactive diagnostic imaging agent |
| JPWO2008056481A1 (ja) * | 2006-11-09 | 2010-02-25 | 日本メジフィジックス株式会社 | 放射性画像診断剤 |
| JP2012502060A (ja) * | 2008-09-05 | 2012-01-26 | モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド | 放射性ヨウ素化ベンズアミド誘導体の薬学的組成物およびそれを作製する方法 |
| JP2012524064A (ja) * | 2009-04-15 | 2012-10-11 | ランセウス メディカル イメージング， インコーポレイテッド | アスコルビン酸による放射性医薬組成物の安定化 |
| US9687571B2 (en) | 2009-04-15 | 2017-06-27 | Lantheus Medical Imaging, Inc. | Stabilization of radiopharmaceutical compositions using ascorbic acid |
| JP2016510342A (ja) * | 2013-02-15 | 2016-04-07 | トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 腫瘍画像化のためのキット |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002253999A1 (en) | 2002-09-12 |
| IL157359A0 (en) | 2004-02-19 |
| BR0207315A (pt) | 2004-02-10 |
| WO2002067859A2 (en) | 2002-09-06 |
| US6713042B2 (en) | 2004-03-30 |
| US20020122769A1 (en) | 2002-09-05 |
| CN1503680A (zh) | 2004-06-09 |
| EP1365813A2 (en) | 2003-12-03 |
| EP1365813A4 (en) | 2006-03-22 |
| MXPA03007595A (es) | 2003-12-04 |
| CZ20032597A3 (cs) | 2004-12-15 |
| HUP0304083A2 (hu) | 2004-03-29 |
| WO2002067859A3 (en) | 2002-11-28 |
| CA2438204A1 (en) | 2002-09-06 |
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