BR0207315A - Análogos de ácido ascórbico para metalorradiofármacos - Google Patents

Análogos de ácido ascórbico para metalorradiofármacos

Info

Publication number
BR0207315A
BR0207315A BR0207315-3A BR0207315A BR0207315A BR 0207315 A BR0207315 A BR 0207315A BR 0207315 A BR0207315 A BR 0207315A BR 0207315 A BR0207315 A BR 0207315A
Authority
BR
Brazil
Prior art keywords
ascorbic acid
metalloradiopharmaceuticals
acid analogues
preparation
relates
Prior art date
Application number
BR0207315-3A
Other languages
English (en)
Inventor
Shuang Liu
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of BR0207315A publication Critical patent/BR0207315A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"ANáLOGOS DE áCIDO ASCóRBICO PARA METALORRADIOFáRMACOS". A invenção diz respeito ao uso de análogos de ácido ascórbico como reagentes tamponantes e agentes quelantes para a preparação de metalorradiofármacos. Também, invenção diz respeito ao uso de ácido ascórbico como um reagente tamponante, um agente quelante e um estabilizador para a preparação e estabilização de radiofármacos e processos para produzir e utilizá-los.
BR0207315-3A 2001-02-26 2002-02-22 Análogos de ácido ascórbico para metalorradiofármacos BR0207315A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27138901P 2001-02-26 2001-02-26
PCT/US2002/005155 WO2002067859A2 (en) 2001-02-26 2002-02-22 Ascorbic acid analogs for metalloradiopharmaceuticals

Publications (1)

Publication Number Publication Date
BR0207315A true BR0207315A (pt) 2004-02-10

Family

ID=23035343

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0207315-3A BR0207315A (pt) 2001-02-26 2002-02-22 Análogos de ácido ascórbico para metalorradiofármacos

Country Status (12)

Country Link
US (1) US6713042B2 (pt)
EP (1) EP1365813A4 (pt)
JP (1) JP2004529884A (pt)
CN (1) CN1503680A (pt)
AU (1) AU2002253999A1 (pt)
BR (1) BR0207315A (pt)
CA (1) CA2438204A1 (pt)
CZ (1) CZ20032597A3 (pt)
HU (1) HUP0304083A2 (pt)
IL (1) IL157359A0 (pt)
MX (1) MXPA03007595A (pt)
WO (1) WO2002067859A2 (pt)

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US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089470A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
GB0427392D0 (en) * 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
TW200808795A (en) * 2006-05-19 2008-02-16 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
CA2655826A1 (en) * 2006-06-21 2007-12-27 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
US10328164B2 (en) * 2006-06-21 2019-06-25 Ge Healthcare Limited Radiopharmaceutical products
US20100056826A1 (en) * 2006-11-09 2010-03-04 Nihon Medi-Physicis Co., Ltd. Radioactive diagnostic imaging agent
KR20090091287A (ko) * 2006-11-17 2009-08-27 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
US8207189B2 (en) * 2006-11-30 2012-06-26 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
JP5159636B2 (ja) * 2006-12-21 2013-03-06 日本メジフィジックス株式会社 放射性画像診断剤
KR101485445B1 (ko) 2007-02-13 2015-01-22 니혼 메디피직스 가부시키가이샤 방사성 화상진단제의 제조 방법
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
EP2218463A1 (en) * 2007-10-30 2010-08-18 Nihon Medi-Physics Co., Ltd. Use of novel compound having affinity for amyloid, and process for production of the same
WO2009057577A1 (ja) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. 新規アミロイド親和性化合物の使用及び製造方法
US20100284912A1 (en) * 2007-12-04 2010-11-11 Bracco Diagnostics Inc. Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
CA2736237A1 (en) * 2008-09-05 2010-03-11 Molecular Insight Pharmaceuticals, Inc. Pharmaceutical composition of a radioiodinated benzamide derivative and methods of making the same
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
PT2419096T (pt) 2009-04-15 2020-02-19 Lantheus Medical Imaging Inc Estabilização de composições radiofarmacêuticas utilizando ácido ascórbico
US9321095B2 (en) 2010-06-30 2016-04-26 General Electric Company Apparatuses and methods for cutting porous substrates
WO2013093099A1 (en) * 2011-12-22 2013-06-27 Piramal Imaging Sa Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof
US9550704B2 (en) 2012-05-24 2017-01-24 Futurechem Co., Ltd. Method for synthesizing radiopharmaceuticals using a cartridge
US20140147381A1 (en) * 2012-11-29 2014-05-29 Gregory David Espenan 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment
US20150374861A1 (en) * 2013-02-15 2015-12-31 Thomas Jefferson Unversity Kit for tumor imaging
JP6500105B2 (ja) * 2014-11-27 2019-04-10 セルトリオン・インコーポレイテッド ペプチドが結合された安定したアスコルビン酸誘導体、その製造方法、及びそれを含む化粧料組成物
TWI604853B (zh) * 2016-05-03 2017-11-11 行政院原子能委員會核能研究所 放射免疫複合體、診療劑及套組
CN107167540B (zh) * 2017-07-08 2019-07-30 万舒（北京）医药科技有限公司 测定人尿液生物样品中的DTPA-Zn的方法

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Also Published As

Publication number Publication date
WO2002067859A3 (en) 2002-11-28
US6713042B2 (en) 2004-03-30
WO2002067859A2 (en) 2002-09-06
MXPA03007595A (es) 2003-12-04
IL157359A0 (en) 2004-02-19
US20020122769A1 (en) 2002-09-05
CN1503680A (zh) 2004-06-09
CZ20032597A3 (cs) 2004-12-15
EP1365813A2 (en) 2003-12-03
CA2438204A1 (en) 2002-09-06
EP1365813A4 (en) 2006-03-22
AU2002253999A1 (en) 2002-09-12
HUP0304083A2 (hu) 2004-03-29
JP2004529884A (ja) 2004-09-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.