MXPA03007595A - Analogos de acido ascorbico para metalorradiofarmaceuticos. - Google Patents

Analogos de acido ascorbico para metalorradiofarmaceuticos.

Info

Publication number
MXPA03007595A
MXPA03007595A MXPA03007595A MXPA03007595A MXPA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A MX PA03007595 A MXPA03007595 A MX PA03007595A
Authority
MX
Mexico
Prior art keywords
metalloradiopharmaceuticals
ascorbic acid
acid analogs
analogs
ascorbic
Prior art date
Application number
MXPA03007595A
Other languages
English (en)
Inventor
Shuang Liu
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of MXPA03007595A publication Critical patent/MXPA03007595A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation
MXPA03007595A 2001-02-26 2002-02-22 Analogos de acido ascorbico para metalorradiofarmaceuticos. MXPA03007595A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27138901P 2001-02-26 2001-02-26
PCT/US2002/005155 WO2002067859A2 (en) 2001-02-26 2002-02-22 Ascorbic acid analogs for metalloradiopharmaceuticals

Publications (1)

Publication Number Publication Date
MXPA03007595A true MXPA03007595A (es) 2003-12-04

Family

ID=23035343

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007595A MXPA03007595A (es) 2001-02-26 2002-02-22 Analogos de acido ascorbico para metalorradiofarmaceuticos.

Country Status (12)

Country Link
US (1) US6713042B2 (es)
EP (1) EP1365813A4 (es)
JP (1) JP2004529884A (es)
CN (1) CN1503680A (es)
AU (1) AU2002253999A1 (es)
BR (1) BR0207315A (es)
CA (1) CA2438204A1 (es)
CZ (1) CZ20032597A3 (es)
HU (1) HUP0304083A2 (es)
IL (1) IL157359A0 (es)
MX (1) MXPA03007595A (es)
WO (1) WO2002067859A2 (es)

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DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
US20050089470A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
GB0427392D0 (en) * 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
EP2019103B1 (en) * 2006-05-19 2011-11-30 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
EP2029178B1 (en) * 2006-06-21 2012-03-14 GE Healthcare Limited Radiopharmaceutical products
EP2042501B1 (en) * 2006-06-21 2017-04-12 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
US20100056826A1 (en) * 2006-11-09 2010-03-04 Nihon Medi-Physicis Co., Ltd. Radioactive diagnostic imaging agent
WO2008059714A1 (fr) * 2006-11-17 2008-05-22 Nihon Medi-Physics Co., Ltd. Composés inédits présentant une affinité pour la substance amyloïde
US8207189B2 (en) * 2006-11-30 2012-06-26 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
AU2007335633A1 (en) * 2006-12-21 2008-06-26 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent
TWI406674B (zh) 2007-02-13 2013-09-01 Nihon Mediphysics Co Ltd Method for manufacturing diagnostic radiographic diagnostic agents
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
AU2008314870A1 (en) * 2007-10-24 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
TW200922628A (en) * 2007-10-30 2009-06-01 Nihon Mediphysics Co Ltd Use of novel compound having affinity for amyloid, and process for production of the same
WO2009057576A1 (ja) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. 新規アミロイド親和性化合物の使用及び製造方法
US20100284912A1 (en) * 2007-12-04 2010-11-11 Bracco Diagnostics Inc. Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
WO2010028281A1 (en) * 2008-09-05 2010-03-11 Molecular Insight Pharmaceuticals, Inc. Pharmaceutical composition of a radioiodinated benzamide derivative and methods of making the same
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
KR20160030589A (ko) 2009-04-15 2016-03-18 랜티우스 메디컬 이메징, 인크. 아스코르브산을 사용한 방사성 약제 조성물의 안정화
US9321095B2 (en) 2010-06-30 2016-04-26 General Electric Company Apparatuses and methods for cutting porous substrates
WO2013093099A1 (en) * 2011-12-22 2013-06-27 Piramal Imaging Sa Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof
KR101479690B1 (ko) * 2012-05-24 2015-01-07 (주)퓨쳐켐 카트리지를 이용한 방사성의약품 제조방법
US20140147381A1 (en) * 2012-11-29 2014-05-29 Gregory David Espenan 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment
CA2901231C (en) * 2013-02-15 2020-06-23 Thomas Jefferson University Kit comprising lyophilized compositions for tumor imaging
WO2016085127A2 (ko) * 2014-11-27 2016-06-02 (주)셀트리온 펩타이드가 결합된 안정한 아스코르빈산 유도체, 그의 제조방법 및 그를 포함하는 화장료 조성물
TWI604853B (zh) * 2016-05-03 2017-11-11 行政院原子能委員會核能研究所 放射免疫複合體、診療劑及套組
CN107167540B (zh) * 2017-07-08 2019-07-30 万舒（北京）医药科技有限公司 测定人尿液生物样品中的DTPA-Zn的方法

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IL42204A (en) * 1972-05-08 1976-09-30 Solco Basel Ag Process and apparatus for the manufacture of injectable radionuclide preparations
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
EP0422713B1 (en) * 1989-10-09 1994-11-09 Unilever N.V. Edible spread
EP0600992B1 (en) * 1991-08-29 2000-09-20 Mallinckrodt Medical, Inc. Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US6066309A (en) * 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
WO1997028181A2 (en) * 1996-02-02 1997-08-07 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
WO2002004030A2 (en) * 2000-07-06 2002-01-17 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions

Also Published As

Publication number Publication date
EP1365813A2 (en) 2003-12-03
US6713042B2 (en) 2004-03-30
CA2438204A1 (en) 2002-09-06
WO2002067859A2 (en) 2002-09-06
HUP0304083A2 (hu) 2004-03-29
BR0207315A (pt) 2004-02-10
US20020122769A1 (en) 2002-09-05
IL157359A0 (en) 2004-02-19
AU2002253999A1 (en) 2002-09-12
CN1503680A (zh) 2004-06-09
CZ20032597A3 (cs) 2004-12-15
JP2004529884A (ja) 2004-09-30
WO2002067859A3 (en) 2002-11-28
EP1365813A4 (en) 2006-03-22

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