JP2004521111A - 局所麻酔薬および使用法 - Google Patents

局所麻酔薬および使用法 Download PDF

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Publication number
JP2004521111A
JP2004521111A JP2002559004A JP2002559004A JP2004521111A JP 2004521111 A JP2004521111 A JP 2004521111A JP 2002559004 A JP2002559004 A JP 2002559004A JP 2002559004 A JP2002559004 A JP 2002559004A JP 2004521111 A JP2004521111 A JP 2004521111A
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Japan
Prior art keywords
administration
hours
formulation
local
bupivacaine
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Pending
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JP2002559004A
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English (en)
Japanese (ja)
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JP2004521111A5 (https=
Inventor
チェイシン，マーク
バスカーク，グレン ヴァン
マスキーウィッツ，リチャード
ケトカー，アモル
バートン，ケビン
シャメーム，モハメド
ランドー，クレイグ
コールズ，セリア
スワントン，ルース
ラクーチュア，ピーター
Original Assignee
ユーロ−セルティーク，エス．エイ．
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Application filed by ユーロ−セルティーク，エス．エイ． filed Critical ユーロ−セルティーク，エス．エイ．
Publication of JP2004521111A publication Critical patent/JP2004521111A/ja
Publication of JP2004521111A5 publication Critical patent/JP2004521111A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2002559004A 2001-01-25 2002-01-25 局所麻酔薬および使用法 Pending JP2004521111A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26418601P 2001-01-25 2001-01-25
PCT/US2002/002461 WO2002058670A1 (en) 2001-01-25 2002-01-25 Local anesthetic, and method of use

Publications (2)

Publication Number Publication Date
JP2004521111A true JP2004521111A (ja) 2004-07-15
JP2004521111A5 JP2004521111A5 (https=) 2005-10-27

Family

ID=23004954

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002559004A Pending JP2004521111A (ja) 2001-01-25 2002-01-25 局所麻酔薬および使用法

Country Status (4)

Country Link
US (1) US20030152637A1 (https=)
EP (1) EP1363602A4 (https=)
JP (1) JP2004521111A (https=)
WO (1) WO2002058670A1 (https=)

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WO2007081061A1 (ja) * 2006-01-16 2007-07-19 Japan Science And Technology Agency 神経因性疼痛治療剤
JP2008543876A (ja) 2005-06-17 2008-12-04 ウイスコンシン アラムニ リサーチ ファンデーション 癌の化学療法および放射線療法の際に細胞を保護するための局所的血管収縮剤および方法
JP2010530435A (ja) * 2007-06-19 2010-09-09 ウォーソー・オーソペディック・インコーポレーテッド 局所的に投与される低用量のコルチコステロイド
JP2011503213A (ja) * 2007-11-19 2011-01-27 カプスレイテッド システムズ インコーポレイテッド マイクロ粒子を使用する局所麻酔薬の持続放出および手術適用方法
JP2011508791A (ja) * 2008-04-18 2011-03-17 ウォーソー・オーソペディック・インコーポレーテッド 生物分解性ポリマー担体中のフルオシノロン製剤
JP2011518164A (ja) * 2008-04-18 2011-06-23 ウォーソー・オーソペディック・インコーポレーテッド 生分解性材料中のデキサメタゾン配合物
JP2011518187A (ja) * 2008-04-18 2011-06-23 メドトロニック，インコーポレイテッド 局所麻酔薬を含む術後疼痛を処置する方法および組成物
JP4865792B2 (ja) * 2005-07-12 2012-02-01 赴朝 李 局所麻酔薬の効果増強・時間延長剤
JP2019514976A (ja) * 2016-05-05 2019-06-06 リクイディア・テクノロジーズ・インコーポレーテッド 負荷と放出が正確に制御された術後疼痛用粒子

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