JP2004519412A5 - - Google Patents
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- Publication number
- JP2004519412A5 JP2004519412A5 JP2001574111A JP2001574111A JP2004519412A5 JP 2004519412 A5 JP2004519412 A5 JP 2004519412A5 JP 2001574111 A JP2001574111 A JP 2001574111A JP 2001574111 A JP2001574111 A JP 2001574111A JP 2004519412 A5 JP2004519412 A5 JP 2004519412A5
- Authority
- JP
- Japan
- Prior art keywords
- keto
- composition
- prostaglandin compound
- prostaglandin
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 27
- 125000000217 alkyl group Chemical group 0.000 claims 12
- 125000000623 heterocyclic group Chemical group 0.000 claims 10
- 125000003545 alkoxy group Chemical group 0.000 claims 8
- 125000003118 aryl group Chemical group 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000004043 oxo group Chemical group O=* 0.000 claims 6
- -1 13,14-dihydro-15-keto-prostaglandin compound Chemical class 0.000 claims 4
- 125000001931 aliphatic group Chemical group 0.000 claims 4
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 210000004185 liver Anatomy 0.000 claims 4
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 239000003761 preservation solution Substances 0.000 claims 2
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19489400P | 2000-04-06 | 2000-04-06 | |
| PCT/JP2001/002938 WO2001076593A2 (en) | 2000-04-06 | 2001-04-05 | Bile secretion promoting composition a 15-keto prostaglandin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008148107A Division JP5073588B2 (ja) | 2000-04-06 | 2008-06-05 | １５−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004519412A JP2004519412A (ja) | 2004-07-02 |
| JP2004519412A5 true JP2004519412A5 (https=) | 2005-06-30 |
| JP4183943B2 JP4183943B2 (ja) | 2008-11-19 |
Family
ID=22719290
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001574111A Expired - Fee Related JP4183943B2 (ja) | 2000-04-06 | 2001-04-05 | １５−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 |
| JP2008148107A Expired - Fee Related JP5073588B2 (ja) | 2000-04-06 | 2008-06-05 | １５−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008148107A Expired - Fee Related JP5073588B2 (ja) | 2000-04-06 | 2008-06-05 | １５−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6469062B2 (https=) |
| EP (1) | EP1267883B1 (https=) |
| JP (2) | JP4183943B2 (https=) |
| KR (1) | KR100874626B1 (https=) |
| CN (1) | CN1241570C (https=) |
| AR (1) | AR030277A1 (https=) |
| AT (1) | ATE433754T1 (https=) |
| AU (2) | AU2001244727B2 (https=) |
| BR (1) | BR0107544A (https=) |
| CA (1) | CA2404767C (https=) |
| DE (1) | DE60139002D1 (https=) |
| MX (1) | MXPA02009915A (https=) |
| NZ (1) | NZ521784A (https=) |
| TW (1) | TWI232750B (https=) |
| WO (1) | WO2001076593A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1267883B1 (en) * | 2000-04-06 | 2009-06-17 | Sucampo AG | Bile secretion promoting composition for liver transplantation containing a 15-keto-prostaglandin |
| EP1420794B1 (en) | 2001-08-31 | 2017-12-27 | Sucampo AG | Prostaglandin analogs as chloride channel openers |
| AR037524A1 (es) | 2001-11-14 | 2004-11-17 | Sucampo Ag | Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion |
| TWI263505B (en) * | 2001-11-19 | 2006-10-11 | Sucampo Ag | Pharmaceutical composition comprising a C1C-2 channel opener |
| EP1575596B1 (en) * | 2002-12-27 | 2016-06-22 | Sucampo AG | Derivatives of prostaglandins for treating irritable bowel syndrome and/or functional dyspepsia |
| RU2468800C2 (ru) * | 2005-04-12 | 2012-12-10 | Сукампо Аг | Комбинированное применение производного простагландина и ингибитора протонового насоса для лечения желудочно-кишечных заболеваний |
| WO2007008697A2 (en) * | 2005-07-08 | 2007-01-18 | University Of Chicago | Compositions and methods for refolding of denatured proteins |
| CA2642744C (en) * | 2006-02-28 | 2015-02-24 | Sucampo Ag | Method and composition for treating chronic obstructive pulmonary disease |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| JP6957610B2 (ja) * | 2016-10-06 | 2021-11-02 | スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ | 医薬品用途のための多層ビーズ |
| KR102595299B1 (ko) | 2020-10-12 | 2023-10-26 | 류형준 | 담즙 분비 촉진 효능이 있는 식품 조성물 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
| JPS6327433A (ja) | 1986-07-21 | 1988-02-05 | Teijin Ltd | 肝疾患治療剤 |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| US5076569A (en) * | 1989-09-15 | 1991-12-31 | Gootter Steven M | Contoured grip for exercising the hand |
| CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
| TW224942B (https=) | 1990-04-04 | 1994-06-11 | Adka Ueno Kk | |
| ATE174221T1 (de) * | 1990-05-01 | 1998-12-15 | R Tech Ueno Ltd | Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten |
| JPH069404A (ja) | 1992-06-23 | 1994-01-18 | Ono Pharmaceut Co Ltd | 臓器移植用薬剤 |
| CA2150287C (en) * | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| JP3183615B2 (ja) * | 1994-06-03 | 2001-07-09 | 株式会社アールテック・ウエノ | 肝・胆道系疾患処置剤 |
| EP1267883B1 (en) * | 2000-04-06 | 2009-06-17 | Sucampo AG | Bile secretion promoting composition for liver transplantation containing a 15-keto-prostaglandin |
-
2001
- 2001-04-05 EP EP01917828A patent/EP1267883B1/en not_active Expired - Lifetime
- 2001-04-05 CA CA2404767A patent/CA2404767C/en not_active Expired - Fee Related
- 2001-04-05 DE DE60139002T patent/DE60139002D1/de not_active Expired - Lifetime
- 2001-04-05 CN CNB018105831A patent/CN1241570C/zh not_active Expired - Fee Related
- 2001-04-05 MX MXPA02009915A patent/MXPA02009915A/es active IP Right Grant
- 2001-04-05 WO PCT/JP2001/002938 patent/WO2001076593A2/en not_active Ceased
- 2001-04-05 AU AU2001244727A patent/AU2001244727B2/en not_active Ceased
- 2001-04-05 AT AT01917828T patent/ATE433754T1/de not_active IP Right Cessation
- 2001-04-05 NZ NZ521784A patent/NZ521784A/en not_active IP Right Cessation
- 2001-04-05 AU AU4472701A patent/AU4472701A/xx active Pending
- 2001-04-05 KR KR1020027013275A patent/KR100874626B1/ko not_active Expired - Fee Related
- 2001-04-05 JP JP2001574111A patent/JP4183943B2/ja not_active Expired - Fee Related
- 2001-04-05 BR BR0107544-6A patent/BR0107544A/pt not_active Application Discontinuation
- 2001-04-06 US US09/827,375 patent/US6469062B2/en not_active Expired - Lifetime
- 2001-04-06 AR ARP010101663A patent/AR030277A1/es not_active Application Discontinuation
- 2001-04-06 TW TW090108254A patent/TWI232750B/zh not_active IP Right Cessation
-
2002
- 2002-07-18 US US10/197,403 patent/US20030060506A1/en not_active Abandoned
-
2008
- 2008-06-05 JP JP2008148107A patent/JP5073588B2/ja not_active Expired - Fee Related
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