AR030277A1 - Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirla - Google Patents
Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirlaInfo
- Publication number
- AR030277A1 AR030277A1 ARP010101663A ARP010101663A AR030277A1 AR 030277 A1 AR030277 A1 AR 030277A1 AR P010101663 A ARP010101663 A AR P010101663A AR P010101663 A ARP010101663 A AR P010101663A AR 030277 A1 AR030277 A1 AR 030277A1
- Authority
- AR
- Argentina
- Prior art keywords
- heterocyclic
- keto
- oxo
- aryl
- hydroxy
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 210000004185 liver Anatomy 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 210000000941 bile Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
- A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19489400P | 2000-04-06 | 2000-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR030277A1 true AR030277A1 (es) | 2003-08-20 |
Family
ID=22719290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010101663A AR030277A1 (es) | 2000-04-06 | 2001-04-06 | Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirla |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6469062B2 (https=) |
| EP (1) | EP1267883B1 (https=) |
| JP (2) | JP4183943B2 (https=) |
| KR (1) | KR100874626B1 (https=) |
| CN (1) | CN1241570C (https=) |
| AR (1) | AR030277A1 (https=) |
| AT (1) | ATE433754T1 (https=) |
| AU (2) | AU2001244727B2 (https=) |
| BR (1) | BR0107544A (https=) |
| CA (1) | CA2404767C (https=) |
| DE (1) | DE60139002D1 (https=) |
| MX (1) | MXPA02009915A (https=) |
| NZ (1) | NZ521784A (https=) |
| TW (1) | TWI232750B (https=) |
| WO (1) | WO2001076593A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1267883B1 (en) * | 2000-04-06 | 2009-06-17 | Sucampo AG | Bile secretion promoting composition for liver transplantation containing a 15-keto-prostaglandin |
| EP1420794B1 (en) | 2001-08-31 | 2017-12-27 | Sucampo AG | Prostaglandin analogs as chloride channel openers |
| AR037524A1 (es) | 2001-11-14 | 2004-11-17 | Sucampo Ag | Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion |
| TWI263505B (en) * | 2001-11-19 | 2006-10-11 | Sucampo Ag | Pharmaceutical composition comprising a C1C-2 channel opener |
| EP1575596B1 (en) * | 2002-12-27 | 2016-06-22 | Sucampo AG | Derivatives of prostaglandins for treating irritable bowel syndrome and/or functional dyspepsia |
| RU2468800C2 (ru) * | 2005-04-12 | 2012-12-10 | Сукампо Аг | Комбинированное применение производного простагландина и ингибитора протонового насоса для лечения желудочно-кишечных заболеваний |
| WO2007008697A2 (en) * | 2005-07-08 | 2007-01-18 | University Of Chicago | Compositions and methods for refolding of denatured proteins |
| CA2642744C (en) * | 2006-02-28 | 2015-02-24 | Sucampo Ag | Method and composition for treating chronic obstructive pulmonary disease |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| JP6957610B2 (ja) * | 2016-10-06 | 2021-11-02 | スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ | 医薬品用途のための多層ビーズ |
| KR102595299B1 (ko) | 2020-10-12 | 2023-10-26 | 류형준 | 담즙 분비 촉진 효능이 있는 식품 조성물 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
| JPS6327433A (ja) | 1986-07-21 | 1988-02-05 | Teijin Ltd | 肝疾患治療剤 |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| US5076569A (en) * | 1989-09-15 | 1991-12-31 | Gootter Steven M | Contoured grip for exercising the hand |
| CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
| TW224942B (https=) | 1990-04-04 | 1994-06-11 | Adka Ueno Kk | |
| ATE174221T1 (de) * | 1990-05-01 | 1998-12-15 | R Tech Ueno Ltd | Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten |
| JPH069404A (ja) | 1992-06-23 | 1994-01-18 | Ono Pharmaceut Co Ltd | 臓器移植用薬剤 |
| CA2150287C (en) * | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| JP3183615B2 (ja) * | 1994-06-03 | 2001-07-09 | 株式会社アールテック・ウエノ | 肝・胆道系疾患処置剤 |
| EP1267883B1 (en) * | 2000-04-06 | 2009-06-17 | Sucampo AG | Bile secretion promoting composition for liver transplantation containing a 15-keto-prostaglandin |
-
2001
- 2001-04-05 EP EP01917828A patent/EP1267883B1/en not_active Expired - Lifetime
- 2001-04-05 CA CA2404767A patent/CA2404767C/en not_active Expired - Fee Related
- 2001-04-05 DE DE60139002T patent/DE60139002D1/de not_active Expired - Lifetime
- 2001-04-05 CN CNB018105831A patent/CN1241570C/zh not_active Expired - Fee Related
- 2001-04-05 MX MXPA02009915A patent/MXPA02009915A/es active IP Right Grant
- 2001-04-05 WO PCT/JP2001/002938 patent/WO2001076593A2/en not_active Ceased
- 2001-04-05 AU AU2001244727A patent/AU2001244727B2/en not_active Ceased
- 2001-04-05 AT AT01917828T patent/ATE433754T1/de not_active IP Right Cessation
- 2001-04-05 NZ NZ521784A patent/NZ521784A/en not_active IP Right Cessation
- 2001-04-05 AU AU4472701A patent/AU4472701A/xx active Pending
- 2001-04-05 KR KR1020027013275A patent/KR100874626B1/ko not_active Expired - Fee Related
- 2001-04-05 JP JP2001574111A patent/JP4183943B2/ja not_active Expired - Fee Related
- 2001-04-05 BR BR0107544-6A patent/BR0107544A/pt not_active Application Discontinuation
- 2001-04-06 US US09/827,375 patent/US6469062B2/en not_active Expired - Lifetime
- 2001-04-06 AR ARP010101663A patent/AR030277A1/es not_active Application Discontinuation
- 2001-04-06 TW TW090108254A patent/TWI232750B/zh not_active IP Right Cessation
-
2002
- 2002-07-18 US US10/197,403 patent/US20030060506A1/en not_active Abandoned
-
2008
- 2008-06-05 JP JP2008148107A patent/JP5073588B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008291033A (ja) | 2008-12-04 |
| JP2004519412A (ja) | 2004-07-02 |
| NZ521784A (en) | 2005-04-29 |
| KR100874626B1 (ko) | 2008-12-17 |
| US20030060506A1 (en) | 2003-03-27 |
| ATE433754T1 (de) | 2009-07-15 |
| JP5073588B2 (ja) | 2012-11-14 |
| KR20020087123A (ko) | 2002-11-21 |
| JP4183943B2 (ja) | 2008-11-19 |
| CA2404767C (en) | 2010-12-07 |
| US6469062B2 (en) | 2002-10-22 |
| EP1267883A2 (en) | 2003-01-02 |
| CN1450899A (zh) | 2003-10-22 |
| TWI232750B (en) | 2005-05-21 |
| US20020004524A1 (en) | 2002-01-10 |
| CA2404767A1 (en) | 2001-10-18 |
| CN1241570C (zh) | 2006-02-15 |
| WO2001076593A3 (en) | 2002-07-11 |
| EP1267883B1 (en) | 2009-06-17 |
| BR0107544A (pt) | 2005-01-11 |
| DE60139002D1 (de) | 2009-07-30 |
| AU2001244727B2 (en) | 2006-08-10 |
| AU4472701A (en) | 2001-10-23 |
| WO2001076593A2 (en) | 2001-10-18 |
| MXPA02009915A (es) | 2003-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |