JP2004518665A5 - - Google Patents

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Publication number
JP2004518665A5
JP2004518665A5 JP2002552533A JP2002552533A JP2004518665A5 JP 2004518665 A5 JP2004518665 A5 JP 2004518665A5 JP 2002552533 A JP2002552533 A JP 2002552533A JP 2002552533 A JP2002552533 A JP 2002552533A JP 2004518665 A5 JP2004518665 A5 JP 2004518665A5
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JP
Japan
Prior art keywords
vitro elution
elution kinetics
kinetics
vitro
elution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002552533A
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English (en)
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JP2004518665A (ja
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Publication date
Priority claimed from FR0017015A external-priority patent/FR2818552B1/fr
Application filed filed Critical
Publication of JP2004518665A publication Critical patent/JP2004518665A/ja
Publication of JP2004518665A5 publication Critical patent/JP2004518665A5/ja
Pending legal-status Critical Current

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In vitro溶出動態を示す。 In vitro溶出動態を示す。 In vitro溶出動態を示す。 In vitro溶出動態を示す。 In vitro溶出動態を示す。
JP2002552533A 2000-12-26 2001-12-21 イバブラジン制御放出のための熱成形可能な固形医薬組成物 Pending JP2004518665A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0017015A FR2818552B1 (fr) 2000-12-26 2000-12-26 Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine
PCT/FR2001/004134 WO2002051387A1 (fr) 2000-12-26 2001-12-21 Composition pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009295406A Division JP2010100641A (ja) 2000-12-26 2009-12-25 イバブラジン制御放出のための熱成形可能な固形医薬組成物

Publications (2)

Publication Number Publication Date
JP2004518665A JP2004518665A (ja) 2004-06-24
JP2004518665A5 true JP2004518665A5 (ja) 2005-06-02

Family

ID=8858190

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002552533A Pending JP2004518665A (ja) 2000-12-26 2001-12-21 イバブラジン制御放出のための熱成形可能な固形医薬組成物
JP2009295406A Pending JP2010100641A (ja) 2000-12-26 2009-12-25 イバブラジン制御放出のための熱成形可能な固形医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009295406A Pending JP2010100641A (ja) 2000-12-26 2009-12-25 イバブラジン制御放出のための熱成形可能な固形医薬組成物

Country Status (27)

Country Link
US (1) US20040028743A1 (ja)
EP (1) EP1345594B1 (ja)
JP (2) JP2004518665A (ja)
KR (1) KR100542472B1 (ja)
CN (1) CN1203844C (ja)
AT (1) ATE352290T1 (ja)
AU (1) AU2002228119B2 (ja)
BR (1) BR0116548A (ja)
CA (1) CA2432645A1 (ja)
CY (1) CY1106390T1 (ja)
CZ (1) CZ304587B6 (ja)
DE (1) DE60126332T2 (ja)
DK (1) DK1345594T3 (ja)
EA (1) EA005814B1 (ja)
ES (1) ES2280420T3 (ja)
FR (1) FR2818552B1 (ja)
HK (1) HK1060514A1 (ja)
HU (1) HU229410B1 (ja)
MX (1) MXPA03005840A (ja)
NO (1) NO333776B1 (ja)
NZ (1) NZ526406A (ja)
PL (1) PL203835B1 (ja)
PT (1) PT1345594E (ja)
SI (1) SI1345594T1 (ja)
SK (1) SK286413B6 (ja)
WO (1) WO2002051387A1 (ja)
ZA (1) ZA200304441B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2818552B1 (fr) * 2000-12-26 2003-02-07 Servier Lab Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine
FR2834896B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'ivabradine
TWI357815B (en) * 2003-06-27 2012-02-11 Euro Celtique Sa Multiparticulates
US20060165790A1 (en) * 2003-06-27 2006-07-27 Malcolm Walden Multiparticulates
GB2418854B (en) 2004-08-31 2009-12-23 Euro Celtique Sa Multiparticulates
FR2882553B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882556B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
WO2010128525A2 (en) 2009-05-04 2010-11-11 Dinesh Shantilal Patel A formulation of ivabradine for treating the cardiovascular disease
US20130116239A1 (en) 2010-06-14 2013-05-09 ratiopharm GnbH Ivabradine-containing pharmaceutical composition with modified release
CN101897682B (zh) * 2010-07-13 2012-02-15 石药集团欧意药业有限公司 一种伊伐布雷定或其可药用盐固体制剂及其制备方法
CN102908327B (zh) * 2011-08-05 2015-03-11 江苏恒瑞医药股份有限公司 伊伐布雷定或其可药用盐的缓释制剂
EP3082772A1 (en) * 2013-12-20 2016-10-26 Synhton B.V. Pharmaceutical composition comprising amorphous ivabradine
EP3025705B8 (en) 2014-11-25 2018-11-28 Sanofi Ilaç Sanayi ve Ticaret Anonim Sirketi Stable ivabradine formulations
CN104398486B (zh) * 2014-12-08 2018-01-12 武汉武药科技有限公司 一种盐酸伊伐布雷定渗透泵控释片及其制备方法
EP3366282A1 (en) 2017-02-28 2018-08-29 Sanovel Ilac Sanayi ve Ticaret A.S. Solid oral pharmaceutical compositions of ivabradine
KR20190001340A (ko) * 2017-06-27 2019-01-04 에리슨제약(주) 이바브라딘을 포함하는 서방성 약제학적 조성물 및 이의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2681862B1 (fr) * 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
CA2231050A1 (en) * 1995-09-07 1997-03-13 Biovail International Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
CN1159012C (zh) * 1997-08-26 2004-07-28 阿旺蒂斯制药公司 用于组合哌啶子基烷醇-减充血剂的药物组合物
US6673367B1 (en) * 1998-12-17 2004-01-06 Euro-Celtique, S.A. Controlled/modified release oral methylphenidate formulations
DE19901040A1 (de) * 1999-01-14 2000-07-20 Knoll Ag Arzneiformen mit gesteuerter Freisetzung, enthaltend gut wasserlösliche Wirkstoffe
FR2795326B1 (fr) * 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
FR2818552B1 (fr) * 2000-12-26 2003-02-07 Servier Lab Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine

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