JP2004512262A5 - - Google Patents
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- JP2004512262A5 JP2004512262A5 JP2002503341A JP2002503341A JP2004512262A5 JP 2004512262 A5 JP2004512262 A5 JP 2004512262A5 JP 2002503341 A JP2002503341 A JP 2002503341A JP 2002503341 A JP2002503341 A JP 2002503341A JP 2004512262 A5 JP2004512262 A5 JP 2004512262A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- pharmaceutical composition
- composition according
- antibody fragment
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000008194 pharmaceutical composition Substances 0.000 description 28
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 19
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 19
- 210000003719 b-lymphocyte Anatomy 0.000 description 15
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 description 9
- 230000000779 depleting effect Effects 0.000 description 8
- 230000003211 malignant effect Effects 0.000 description 7
- 208000023275 Autoimmune disease Diseases 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 6
- 229960004641 rituximab Drugs 0.000 description 6
- 201000011510 cancer Diseases 0.000 description 5
- 206010025323 Lymphomas Diseases 0.000 description 4
- 230000036210 malignancy Effects 0.000 description 4
- 230000002285 radioactive effect Effects 0.000 description 4
- 230000000890 antigenic effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 208000032839 leukemia Diseases 0.000 description 2
- 208000002008 AIDS-Related Lymphoma Diseases 0.000 description 1
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010025312 Lymphoma AIDS related Diseases 0.000 description 1
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000009175 antibody therapy Methods 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000002659 cell therapy Methods 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 201000003444 follicular lymphoma Diseases 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000000527 lymphocytic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical group [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21266800P | 2000-06-20 | 2000-06-20 | |
| PCT/US2001/018939 WO2001097858A2 (en) | 2000-06-20 | 2001-06-14 | Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004512262A JP2004512262A (ja) | 2004-04-22 |
| JP2004512262A5 true JP2004512262A5 (enExample) | 2008-08-14 |
Family
ID=22791978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002503341A Abandoned JP2004512262A (ja) | 2000-06-20 | 2001-06-14 | 非放射性抗cd20抗体/放射標識抗cd22抗体の組合せ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6846476B2 (enExample) |
| EP (2) | EP2052742A1 (enExample) |
| JP (1) | JP2004512262A (enExample) |
| AU (2) | AU2001268363B2 (enExample) |
| CA (1) | CA2411102A1 (enExample) |
| WO (1) | WO2001097858A2 (enExample) |
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-
2001
- 2001-06-14 JP JP2002503341A patent/JP2004512262A/ja not_active Abandoned
- 2001-06-14 EP EP09150477A patent/EP2052742A1/en not_active Withdrawn
- 2001-06-14 AU AU2001268363A patent/AU2001268363B2/en not_active Ceased
- 2001-06-14 EP EP01946293A patent/EP1299128A2/en not_active Withdrawn
- 2001-06-14 CA CA002411102A patent/CA2411102A1/en not_active Abandoned
- 2001-06-14 AU AU6836301A patent/AU6836301A/xx active Pending
- 2001-06-14 WO PCT/US2001/018939 patent/WO2001097858A2/en not_active Ceased
- 2001-06-20 US US09/883,962 patent/US6846476B2/en not_active Expired - Fee Related
-
2003
- 2003-11-10 US US10/703,669 patent/US20050112060A1/en not_active Abandoned
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