JP2004505761A - 微小粒子 - Google Patents

微小粒子 Download PDF

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Publication number
JP2004505761A
JP2004505761A JP2002518933A JP2002518933A JP2004505761A JP 2004505761 A JP2004505761 A JP 2004505761A JP 2002518933 A JP2002518933 A JP 2002518933A JP 2002518933 A JP2002518933 A JP 2002518933A JP 2004505761 A JP2004505761 A JP 2004505761A
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JP
Japan
Prior art keywords
particles
nozzle
diameter
stream
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002518933A
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English (en)
Japanese (ja)
Other versions
JP2004505761A5 (enExample
Inventor
キム，キェキョーン
パック，ダニエル，ダブリュー．
バークランド，コーリー，ジェイ．
Original Assignee
ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ filed Critical ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ
Publication of JP2004505761A publication Critical patent/JP2004505761A/ja
Publication of JP2004505761A5 publication Critical patent/JP2004505761A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2002518933A 2000-08-15 2001-08-15 微小粒子 Pending JP2004505761A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22562000P 2000-08-15 2000-08-15
US22552500P 2000-08-15 2000-08-15
PCT/US2001/025674 WO2002013786A2 (en) 2000-08-15 2001-08-15 Method of forming microparticles

Publications (2)

Publication Number Publication Date
JP2004505761A true JP2004505761A (ja) 2004-02-26
JP2004505761A5 JP2004505761A5 (enExample) 2008-11-06

Family

ID=26919678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002518933A Pending JP2004505761A (ja) 2000-08-15 2001-08-15 微小粒子

Country Status (9)

Country Link
US (3) US6669961B2 (enExample)
EP (1) EP1355630B1 (enExample)
JP (1) JP2004505761A (enExample)
KR (2) KR100902625B1 (enExample)
AT (1) ATE449596T1 (enExample)
AU (1) AU2001284982A1 (enExample)
CA (1) CA2419115C (enExample)
DE (1) DE60140625D1 (enExample)
WO (1) WO2002013786A2 (enExample)

Cited By (30)

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JP2006075708A (ja) * 2004-09-09 2006-03-23 Optonix Seimitsu:Kk 球状超微粒子及びその製造方法
JP2006077252A (ja) * 2005-09-09 2006-03-23 Optonix Seimitsu:Kk 加圧振動及び噴射造粒による超微粒子
JP2008502463A (ja) * 2004-06-01 2008-01-31 ボストン サイエンティフィック リミテッド 塞栓術
WO2008053988A1 (fr) * 2006-11-02 2008-05-08 National University Corporation Nagoya University Procédé de production de microcapsules
JP2008520407A (ja) * 2004-11-10 2008-06-19 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 多相ナノ粒子
JP2008528268A (ja) * 2005-01-28 2008-07-31 ウニベルシダ デ セビリャ マイクロメートル及びナノメートルのサイズの粒子を得るための方法及び装置
JP2011506271A (ja) * 2007-10-23 2011-03-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ ポリマー微粒子を調製する方法
US7947772B2 (en) 2004-11-10 2011-05-24 The Regents Of The University Of Michigan Multiphasic nano-components comprising colorants
US8043480B2 (en) 2004-11-10 2011-10-25 The Regents Of The University Of Michigan Methods for forming biodegradable nanocomponents with controlled shapes and sizes via electrified jetting
US8187708B2 (en) 2004-11-10 2012-05-29 The Regents Of The University Of Michigan Microphasic micro-components and methods for controlling morphology via electrified jetting
US8241651B2 (en) 2004-11-10 2012-08-14 The Regents Of The University Of Michigan Multiphasic biofunctional nano-components and methods for use thereof
US9482861B2 (en) 2010-10-22 2016-11-01 The Regents Of The University Of Michigan Optical devices with switchable particles
JP2018502167A (ja) * 2015-01-20 2018-01-25 ヒアロ テクノロジーズ，エルエルシー ミクロスフェアの調製方法
JP2019522319A (ja) * 2016-06-23 2019-08-08 アマスタン・テクノロジーズ・エル・エル・シー リチウムイオン電池材料
US11273491B2 (en) 2018-06-19 2022-03-15 6K Inc. Process for producing spheroidized powder from feedstock materials
US11311938B2 (en) 2019-04-30 2022-04-26 6K Inc. Mechanically alloyed powder feedstock
US11577314B2 (en) 2015-12-16 2023-02-14 6K Inc. Spheroidal titanium metallic powders with custom microstructures
US11590568B2 (en) 2019-12-19 2023-02-28 6K Inc. Process for producing spheroidized powder from feedstock materials
US11611130B2 (en) 2019-04-30 2023-03-21 6K Inc. Lithium lanthanum zirconium oxide (LLZO) powder
US11717886B2 (en) 2019-11-18 2023-08-08 6K Inc. Unique feedstocks for spherical powders and methods of manufacturing
US11839919B2 (en) 2015-12-16 2023-12-12 6K Inc. Spheroidal dehydrogenated metals and metal alloy particles
US11855278B2 (en) 2020-06-25 2023-12-26 6K, Inc. Microcomposite alloy structure
US11919071B2 (en) 2020-10-30 2024-03-05 6K Inc. Systems and methods for synthesis of spheroidized metal powders
US11963287B2 (en) 2020-09-24 2024-04-16 6K Inc. Systems, devices, and methods for starting plasma
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US12094688B2 (en) 2022-08-25 2024-09-17 6K Inc. Plasma apparatus and methods for processing feed material utilizing a powder ingress preventor (PIP)
US12195338B2 (en) 2022-12-15 2025-01-14 6K Inc. Systems, methods, and device for pyrolysis of methane in a microwave plasma for hydrogen and structured carbon powder production
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US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
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WO2002013786A3 (en) 2003-08-28
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CA2419115C (en) 2011-03-08
WO2002013786A2 (en) 2002-02-21
US7368130B2 (en) 2008-05-06
EP1355630B1 (en) 2009-11-25
US20040022939A1 (en) 2004-02-05
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CA2419115A1 (en) 2002-02-21

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