JP2004501185A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004501185A5 JP2004501185A5 JP2002504985A JP2002504985A JP2004501185A5 JP 2004501185 A5 JP2004501185 A5 JP 2004501185A5 JP 2002504985 A JP2002504985 A JP 2002504985A JP 2002504985 A JP2002504985 A JP 2002504985A JP 2004501185 A5 JP2004501185 A5 JP 2004501185A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- manufactured
- animal
- oil
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 241001465754 Metazoa Species 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000008194 pharmaceutical composition Substances 0.000 description 5
- 235000014113 dietary fatty acids Nutrition 0.000 description 4
- 239000000194 fatty acid Substances 0.000 description 4
- 229930195729 fatty acid Natural products 0.000 description 4
- 150000004665 fatty acids Chemical class 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000002500 effect on skin Effects 0.000 description 3
- 208000017520 skin disease Diseases 0.000 description 3
- -1 squalane Chemical class 0.000 description 3
- 235000021355 Stearic acid Nutrition 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 235000013871 bee wax Nutrition 0.000 description 2
- 239000012166 beeswax Substances 0.000 description 2
- 229940092738 beeswax Drugs 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 239000008117 stearic acid Substances 0.000 description 2
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
- 239000004347 Glyceryl monoacetate Substances 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- CEGOLXSVJUTHNZ-UHFFFAOYSA-K aluminium tristearate Chemical compound [Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CEGOLXSVJUTHNZ-UHFFFAOYSA-K 0.000 description 1
- 229940083916 aluminum distearate Drugs 0.000 description 1
- RDIVANOKKPKCTO-UHFFFAOYSA-K aluminum;octadecanoate;hydroxide Chemical compound [OH-].[Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O RDIVANOKKPKCTO-UHFFFAOYSA-K 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 229940082483 carnauba wax Drugs 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- UGMCXQCYOVCMTB-UHFFFAOYSA-K dihydroxy(stearato)aluminium Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[Al](O)O UGMCXQCYOVCMTB-UHFFFAOYSA-K 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 235000019442 glyceryl monoacetate Nutrition 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229940043348 myristyl alcohol Drugs 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000009121 systemic therapy Methods 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0015617.4A GB0015617D0 (en) | 2000-06-26 | 2000-06-26 | Improved preparations for dermal delivery of active substances |
| PCT/GB2001/002823 WO2002000203A1 (en) | 2000-06-26 | 2001-06-26 | Topical pharmaceutical formulations and methods of treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501185A JP2004501185A (ja) | 2004-01-15 |
| JP2004501185A5 true JP2004501185A5 (https=) | 2012-04-26 |
Family
ID=9894412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002504985A Ceased JP2004501185A (ja) | 2000-06-26 | 2001-06-26 | 局所医薬製剤および治療法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US7754240B2 (https=) |
| EP (2) | EP2027851A1 (https=) |
| JP (1) | JP2004501185A (https=) |
| KR (1) | KR20030041871A (https=) |
| CN (1) | CN1438878A (https=) |
| AT (1) | ATE429904T1 (https=) |
| AU (2) | AU2001267686A1 (https=) |
| BR (1) | BR0112356A (https=) |
| CA (1) | CA2413699C (https=) |
| DE (1) | DE60138547D1 (https=) |
| DK (1) | DK1296652T3 (https=) |
| ES (1) | ES2325980T3 (https=) |
| GB (1) | GB0015617D0 (https=) |
| HU (1) | HUP0301121A3 (https=) |
| IL (1) | IL153665A0 (https=) |
| MX (1) | MXPA02012666A (https=) |
| NO (1) | NO333292B1 (https=) |
| PL (1) | PL211890B1 (https=) |
| WO (1) | WO2002000203A1 (https=) |
| ZA (1) | ZA200210224B (https=) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8188043B2 (en) * | 1999-07-28 | 2012-05-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine in therapeutic angiogenesis and vasculogenesis |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| GB2383950B (en) * | 2002-01-11 | 2006-01-18 | Cosmetic Warriors Ltd | Cosmetic product |
| WO2003092784A1 (en) * | 2002-05-06 | 2003-11-13 | Vectura Limited | Application device for topical administration of pharmaceutical agents |
| US20070065463A1 (en) | 2003-06-20 | 2007-03-22 | Ronald Aung-Din | Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions |
| US7718674B2 (en) | 2004-09-27 | 2010-05-18 | Bridge Pharma, Inc. | Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine |
| DE102004059613A1 (de) * | 2004-12-10 | 2006-06-14 | Liedtke, Rainer K., Dr. | Zusammensetzung und Methode einer topischen Therapie von Neurodermitis |
| US20090215753A1 (en) * | 2005-12-07 | 2009-08-27 | Pharmacodex Ltd. | Topical Compositions for Paediatric Use |
| GB0524961D0 (en) * | 2005-12-07 | 2006-01-18 | Pharmakodex Ltd | Transdermal administration of active agents for systemic effect |
| GB0524959D0 (en) * | 2005-12-07 | 2006-01-18 | Pharmakodex Ltd | Topical compositions for treatment of respiratory disorders |
| EP2010133B1 (en) | 2006-03-31 | 2016-05-04 | Stiefel Research Australia Pty Ltd | Foamable suspension gel |
| GB0612556D0 (en) * | 2006-06-23 | 2006-08-02 | Univ Aston | Topical pharmaceutical formulations |
| US20090221703A1 (en) * | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| CA2655809C (en) * | 2006-07-21 | 2013-10-01 | Bridge Pharma, Inc. | Dermal anesthetic compounds |
| US20080287373A1 (en) * | 2007-05-17 | 2008-11-20 | Popp Karl F | Topical skin treating kits |
| GB2450117A (en) * | 2007-06-13 | 2008-12-17 | Reckitt Benckiser Healthcare | A water- and oxygen-occlusive blister tablet pack |
| US9861154B2 (en) * | 2008-07-18 | 2018-01-09 | Biomod Collection Inc. | Articles of manufacture releasing an active ingredient |
| ES2400210T3 (es) | 2008-10-02 | 2013-04-08 | Mylan Inc. | Método para preparar un laminado de adhesivo multicapa |
| CN102470237A (zh) * | 2009-06-26 | 2012-05-23 | 塔里斯生物医药公司 | 用于可植入药物递送装置的固体药物片剂 |
| US8470304B2 (en) | 2009-08-04 | 2013-06-25 | Avidas Pharmaceuticals Llc | Therapeutic vitamin D sun-protecting formulations and methods for their use |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| WO2012010238A1 (en) | 2010-07-17 | 2012-01-26 | Merck Patent Gmbh | Enhancement of penetration and action |
| EP2441444A1 (en) * | 2010-10-14 | 2012-04-18 | Deva Holding Anonim Sirketi | Formulations of cetyl myristate and/or cetyl palmitate |
| JP2013539792A (ja) | 2010-10-15 | 2013-10-28 | ザ プロクター アンド ギャンブル カンパニー | 上皮生態の改善のためのモノアミンオキシダーゼ阻害剤の使用 |
| US8293288B2 (en) | 2011-02-23 | 2012-10-23 | Edna Ma | Pain relieving composition |
| US8512768B2 (en) | 2011-02-23 | 2013-08-20 | Miss Smarty Pants Enterprises, Inc. | Pain relieving composition |
| US11786455B2 (en) | 2011-05-10 | 2023-10-17 | Itochu Chemical Frontier Corporation | Non-aqueous patch |
| ES3034911T3 (en) | 2011-05-10 | 2025-08-26 | Itochu Chemical Frontier Corp | Non-aqueous patch |
| JP5856153B2 (ja) | 2011-05-10 | 2016-02-09 | 伊藤忠ケミカルフロンティア株式会社 | 非水性貼付剤 |
| SI2823815T1 (sl) | 2011-09-27 | 2018-09-28 | Itochu Chemical Frontier Corporation | Ne-vodni obliž |
| US8633178B2 (en) | 2011-11-23 | 2014-01-21 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CN102641275B (zh) * | 2012-05-16 | 2013-04-24 | 江苏圣宝罗药业有限公司 | 复方丙酸氯倍他索与维a酸软膏剂 |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| CN105120839B (zh) * | 2013-02-28 | 2020-07-28 | 湖州惠中济世生物科技有限公司 | 可注射长效局麻药半固体制剂及其组成成分 |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| US9006462B2 (en) | 2013-02-28 | 2015-04-14 | Dermira, Inc. | Glycopyrrolate salts |
| US8558008B2 (en) | 2013-02-28 | 2013-10-15 | Dermira, Inc. | Crystalline glycopyrrolate tosylate |
| JP6114841B2 (ja) | 2013-02-28 | 2017-04-12 | ダーミラ， インク．Ｄｅｒｍｉｒａ， Ｉｎｃ． | グリコピロレート塩 |
| PT2968880T (pt) | 2013-03-15 | 2025-07-07 | Taris Biomedical Llc | Dispositivos de aplicação de fármaco com componente permeável a fármaco |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| CN113413393B (zh) | 2013-08-19 | 2025-03-04 | 塔里斯生物医药公司 | 多单元药物递送装置和方法 |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| EP3145489A1 (en) | 2014-05-22 | 2017-03-29 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| CA2955229C (en) | 2014-07-17 | 2020-03-10 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| RU2016141135A (ru) | 2014-07-29 | 2018-08-28 | Терапьютиксмд, Инк. | Трансдермальный крем |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| KR20170134514A (ko) | 2015-03-23 | 2017-12-06 | 바이오팜엑스 인코포레이티드 | 피부과 사용을 위한 약학 테트라사이클린 조성물 |
| KR102658706B1 (ko) | 2015-04-23 | 2024-04-17 | 타리스 바이오메디컬 엘엘씨 | 약물-투과성 성분을 구비한 약물 전달 장치 및 방법 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| CN108853140A (zh) * | 2018-07-18 | 2018-11-23 | 豆立忠 | 一种多药物模块软膏及其制备方法 |
| EP3846792A4 (en) | 2018-09-06 | 2022-10-12 | Innopharmascreen Inc. | METHODS AND COMPOSITIONS FOR TREATING ASTHMA OR PARKINSON'S DISEASE |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| CN112237547B (zh) * | 2020-09-28 | 2022-08-30 | 安徽美邸康药业有限公司 | 一种药贴成型装置 |
| MX2020011523A (es) * | 2020-10-29 | 2022-05-02 | Exeltis Pharma Mexico S A De C V | Composicion farmaceutica adecuada para administracion vaginal en forma de ovulos y uso de la misma. |
| BE1028968B1 (nl) | 2020-12-29 | 2022-08-01 | Usocore Nv | Harde was zonder BHT |
| HU231751B1 (hu) * | 2022-01-11 | 2026-02-28 | Ödön dr. Wagner | Hatóanyagát hosszabb időn keresztül csak a test hőmérsékletén leadó transzdermális készítmény és eljárás annak előállítására |
| CA3267930A1 (en) * | 2022-09-21 | 2024-03-28 | The Board Of Trustees Of The Leland Stanford Junior University | Synergistic stimulation of mucociliary clearance to treat mucus obstruction in cystic fibrosis and other muco-obstructive disorders |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US308343A (en) * | 1884-11-25 | Pail handle | ||
| US597849A (en) * | 1898-01-25 | Ditching-jack | ||
| US369784A (en) * | 1887-09-13 | fueman | ||
| US151274A (en) * | 1874-05-26 | Improvement in springs for vehicles | ||
| US765986A (en) * | 1902-06-07 | 1904-07-26 | Nat Tube Co | Conical rolls for piercing, expanding, or cross-rolling metal billets or tubular blanks. |
| US863941A (en) * | 1906-06-05 | 1907-08-20 | James M Robbins | Wheelwright-machine. |
| US892890A (en) * | 1907-10-14 | 1908-07-07 | Max A Repelow | Card-index. |
| AU513753B2 (en) * | 1974-07-08 | 1980-12-18 | Johnson & Johnson | Antimicrobial composition |
| DE2551446B2 (de) | 1975-11-15 | 1977-09-15 | Karl Werner Schlüter GmbH, 2000 Ham burg | Verfahren zur herstellung von suppositorien |
| CH637014A5 (de) * | 1978-09-29 | 1983-07-15 | Sandoz Ag | Verfahren zur herstellung von suppositorien. |
| DE2920500A1 (de) * | 1979-05-21 | 1980-11-27 | Boehringer Sohn Ingelheim | Pharmazeutische zubereitung in form eines polyacrylatfilmes |
| US4278679A (en) * | 1980-05-01 | 1981-07-14 | Chromalloy American Corporation | Combination of two or more drugs in a single dosage form wherein one of the drugs is a physostigmine compound |
| FR2515036B1 (fr) * | 1981-10-23 | 1986-12-05 | Oreal | Composition stable a l'oxydation d'anthraline ou de l'un de ses derives et son utilisation dans le traitement des maladies de la peau |
| GB2107588B (en) * | 1981-10-23 | 1985-04-11 | Oreal | Anhydrous compostion based on anthralin or a derivative thereof for the treatment of skin diseases |
| US4892890A (en) | 1984-11-01 | 1990-01-09 | G. D. Searle And Company | External analgesic compositions |
| DE3522060A1 (de) * | 1985-06-20 | 1987-01-08 | Liedtke Pharmed Gmbh | Arzneipflaster fuer systemische anwendungen |
| DE3523454A1 (de) * | 1985-07-01 | 1987-01-08 | Eberhard Prof Dr Nuernberg | Formkoerper |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| FR2633187A1 (fr) | 1988-06-23 | 1989-12-29 | Gafner Paul Felix | Dispositif applicateur cutane d'une solution medicamenteuse pour le traitement dermatologique |
| AU622961B2 (en) * | 1988-12-23 | 1992-04-30 | Westech Industrial Ltd. | Flame arrester having detonation-attenuating means |
| LU87416A1 (fr) * | 1988-12-29 | 1990-07-10 | Cird | Microgranules charges en une substance active,constitues essentiellement d'un triglyceride d'acides gras satures et leur utilisation par voie topique dans le domaine therapeutique |
| US5389686A (en) | 1989-02-20 | 1995-02-14 | Jouveinal Sa | Analgesic properties of fedotozine |
| FR2663007A1 (fr) | 1990-06-08 | 1991-12-13 | Kodak Pathe | Emballage de produits photographiques en bandes. |
| US5121158A (en) * | 1990-10-31 | 1992-06-09 | Umax Data System Inc. | Filter driving mechanism for color optical reader |
| JP3086290B2 (ja) * | 1991-07-26 | 2000-09-11 | エスエス製薬株式会社 | ジクロフェナクナトリウム貼付剤 |
| JPH07258071A (ja) * | 1994-03-22 | 1995-10-09 | Ojiro Yukagaku Kenkyusho:Kk | 粒状皮膚用剤およびその用途 |
| US5597849A (en) | 1994-11-14 | 1997-01-28 | Medical Polymer Technologies, Inc. | Stick formulations for topical drug delivery of therapeutic agents and uses thereof |
| US5785991A (en) * | 1995-06-07 | 1998-07-28 | Alza Corporation | Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate |
| DE19524691A1 (de) | 1995-07-06 | 1997-01-09 | Liedtke Pharmed Gmbh | Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen |
| US5722424A (en) * | 1995-09-29 | 1998-03-03 | Target Therapeutics, Inc. | Multi-coating stainless steel guidewire |
| JPH09169635A (ja) * | 1995-12-20 | 1997-06-30 | Sekisui Chem Co Ltd | 経皮吸収製剤 |
| GB9611356D0 (en) | 1996-05-31 | 1996-08-07 | Howard Alan N | Improvements in or relating to compositions containing Creatine, and other ergogenic compounds |
| WO1999055396A1 (en) * | 1998-04-27 | 1999-11-04 | Surmodics, Inc. | Bioactive agent release coating |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6325807B1 (en) * | 1999-06-11 | 2001-12-04 | Scimed Life Systems, Inc. | Variable strength sheath |
| US6455066B1 (en) * | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
| US6517520B2 (en) * | 2000-12-21 | 2003-02-11 | Ethicon Endo Surgery, Inc. | Peripherally inserted catheter with flushable guide-tube |
-
2000
- 2000-06-26 GB GBGB0015617.4A patent/GB0015617D0/en not_active Ceased
-
2001
- 2001-06-26 JP JP2002504985A patent/JP2004501185A/ja not_active Ceased
- 2001-06-26 MX MXPA02012666A patent/MXPA02012666A/es active IP Right Grant
- 2001-06-26 EP EP07122565A patent/EP2027851A1/en not_active Withdrawn
- 2001-06-26 CN CN01811778A patent/CN1438878A/zh active Pending
- 2001-06-26 WO PCT/GB2001/002823 patent/WO2002000203A1/en not_active Ceased
- 2001-06-26 PL PL360868A patent/PL211890B1/pl not_active IP Right Cessation
- 2001-06-26 BR BR0112356-4A patent/BR0112356A/pt not_active Application Discontinuation
- 2001-06-26 ES ES01945471T patent/ES2325980T3/es not_active Expired - Lifetime
- 2001-06-26 AT AT01945471T patent/ATE429904T1/de active
- 2001-06-26 DK DK01945471T patent/DK1296652T3/da active
- 2001-06-26 AU AU2001267686A patent/AU2001267686A1/en not_active Abandoned
- 2001-06-26 US US10/312,475 patent/US7754240B2/en not_active Expired - Fee Related
- 2001-06-26 KR KR1020027017591A patent/KR20030041871A/ko not_active Withdrawn
- 2001-06-26 IL IL15366501A patent/IL153665A0/xx not_active IP Right Cessation
- 2001-06-26 DE DE60138547T patent/DE60138547D1/de not_active Expired - Lifetime
- 2001-06-26 CA CA2413699A patent/CA2413699C/en not_active Expired - Fee Related
- 2001-06-26 HU HU0301121A patent/HUP0301121A3/hu unknown
- 2001-06-26 EP EP01945471A patent/EP1296652B1/en not_active Expired - Lifetime
-
2002
- 2002-12-18 ZA ZA200210224A patent/ZA200210224B/en unknown
- 2002-12-20 NO NO20026171A patent/NO333292B1/no not_active IP Right Cessation
-
2006
- 2006-06-09 AU AU2006202479A patent/AU2006202479C1/en not_active Ceased
-
2008
- 2008-03-19 US US12/077,331 patent/US20080166413A1/en not_active Abandoned
-
2010
- 2010-07-08 US US12/832,907 patent/US8158613B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004501185A5 (https=) | ||
| EP0786251B1 (en) | Topical preparation containing a suspension of solid lipid particles | |
| AU724741B2 (en) | Antiherpetic pharmaceutical compositions containing acyclovir for topical applicators | |
| RU2238083C2 (ru) | Лечение хронической экземы кожи рук | |
| JP2003528821A (ja) | 局所適用のための薬学的および化粧用の担体または組成物 | |
| JP2002505272A (ja) | 乳化剤としてガラクト脂質物質からなり、導入された活性物質の持続作用を有する水中油型局所用組成物 | |
| IE62871B1 (en) | Compositions with enhanced penetration | |
| ES2249008T3 (es) | Composiciones para el tratamiento del acne. | |
| EP0784975B1 (en) | Use of acetylsalicylic acid in the manufacture of a drug for the treatment of skin injuries | |
| JPH04507397A (ja) | 湿疹治療用薬剤製造における必須脂肪酸の使用法 | |
| RU2339362C2 (ru) | Продукт для ухода за кожей, содержащий жирные кислоты таллового масла и растительные масла, для сухой и шелушащейся кожи и лечения псориаза, дерматита и экземы | |
| US4190669A (en) | Method for treating psoriasis | |
| RU2401104C2 (ru) | Фармацевтическая композиция на основе тилорона местного и наружного применения для лечения гнойно-деструктивных поражений слизистой и кожи, общесистемных заболеваний при иммунодефицитных состояниях | |
| RU2414221C2 (ru) | Фармацевтическая композиция на основе циклоферона местного и наружного применения для лечения гнойно-деструктивных поражений слизистой и кожи, общесистемных заболеваний при иммунодефицитных состояниях | |
| JP2024535972A (ja) | 乾癬を治療するための医薬品の調製におけるマンゴスチン果実殻抽出物の使用 | |
| CA2064476C (en) | Podophyllotoxin preparation containing triglycerides | |
| JP3689137B2 (ja) | アレルギー性皮膚疾患治療用外用剤 | |
| JPH05503295A (ja) | 乾癬の局所的治療のための組成物 | |
| WO2019002367A1 (en) | TOPICAL COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES | |
| EP1675621B1 (en) | Pharmaceutical compositions of lavendustin | |
| HK1092699B (en) | Pharmaceutical compositions of lavendustin | |
| CN112741848A (zh) | 银杏萃取物用于制备治疗局部缺血的医药组合物及用途 | |
| TW202108140A (zh) | 西地那非用於製備治療局部缺血的醫藥組成物及用途 | |
| SK18652000A3 (sk) | Farmaceutická kompozícia na báze erytromycínových solí mastných kyselín s 12 až 22 atómami uhlíka vo zvyšku mastnej kyseliny a použitie týchto erytromycínových solí mastných kyselín na topické liečenie kožných ochorení | |
| JPH03258715A (ja) | 消炎鎮痛外用剤 |