JP2003510037A5 - - Google Patents

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Publication number
JP2003510037A5
JP2003510037A5 JP2001522272A JP2001522272A JP2003510037A5 JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5 JP 2001522272 A JP2001522272 A JP 2001522272A JP 2001522272 A JP2001522272 A JP 2001522272A JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5
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JP
Japan
Prior art keywords
seq
polypeptide
nucleic acid
sequence
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001522272A
Other languages
English (en)
Japanese (ja)
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JP2003510037A (ja
JP4339542B2 (ja
Filing date
Publication date
Priority claimed from US09/393,634 external-priority patent/US6558910B2/en
Application filed filed Critical
Priority claimed from PCT/US2000/024821 external-priority patent/WO2001018050A2/en
Publication of JP2003510037A publication Critical patent/JP2003510037A/ja
Publication of JP2003510037A5 publication Critical patent/JP2003510037A5/ja
Application granted granted Critical
Publication of JP4339542B2 publication Critical patent/JP4339542B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001522272A 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー Expired - Fee Related JP4339542B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/393,634 US6558910B2 (en) 1999-09-10 1999-09-10 SF, a novel family of taste receptors
US09/393,634 1999-09-10
US09/510,332 2000-02-22
US09/510,332 US7244584B2 (en) 1999-09-10 2000-02-22 T2R, a novel family of taste receptors
PCT/US2000/024821 WO2001018050A2 (en) 1999-09-10 2000-09-08 T2r taste receptor family

Publications (3)

Publication Number Publication Date
JP2003510037A JP2003510037A (ja) 2003-03-18
JP2003510037A5 true JP2003510037A5 (enExample) 2007-09-06
JP4339542B2 JP4339542B2 (ja) 2009-10-07

Family

ID=27014384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001522272A Expired - Fee Related JP4339542B2 (ja) 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー

Country Status (10)

Country Link
US (8) US7465550B2 (enExample)
EP (1) EP1214343A2 (enExample)
JP (1) JP4339542B2 (enExample)
CN (1) CN1289525C (enExample)
AU (2) AU773600B2 (enExample)
CA (1) CA2384777A1 (enExample)
IL (1) IL148593A0 (enExample)
MX (1) MXPA02002538A (enExample)
NO (1) NO20021164L (enExample)
WO (1) WO2001018050A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
WO2001018050A2 (en) 1999-09-10 2001-03-15 The Regents Of The University Of California T2r taste receptor family
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
AU2001251258B2 (en) * 2000-04-07 2008-06-05 Senomyx, Inc. T2r taste receptors and genes encoding same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US8030008B2 (en) 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP2327985B2 (en) 2001-06-26 2019-08-21 Senomyx, Inc. T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
EP1502112A4 (en) 2001-07-10 2008-07-23 Senomyx Inc USE OF SPECIFIC T2R TASTE RECIPES TO IDENTIFY CONNECTIONS WHICH BLOCK A BITTER TASTE
EP1523308A4 (en) 2001-07-20 2007-01-10 Us Gov Health & Human Serv PHENYL THIOCARBAMIDE (PTC) TREATMENT RECEPTOR
EP1442117A4 (en) * 2001-10-12 2005-04-27 Univ California CHEMOLIC RECEPTORS OF THE STOMACH DARM TRAKTS
CA2488863A1 (en) 2002-07-29 2004-02-05 Senomyx, Inc. Identification of a novel bitter taste receptor, t2r76
EP2163623A3 (en) * 2002-09-25 2010-05-26 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
WO2004055048A2 (en) 2002-12-18 2004-07-01 Givaudan Sa Chimeric alpha q-gustducin g-proteins
WO2005007891A2 (en) * 2003-06-19 2005-01-27 The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
US7829299B2 (en) 2004-11-18 2010-11-09 Deutsches Institut fur Ernahrungforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts Agonists of bitter taste receptors and uses thereof
CA2597085A1 (en) * 2005-02-08 2006-08-17 Senomyx, Inc. Phuman t2r receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators
WO2007074937A1 (ja) 2005-12-27 2007-07-05 Nihon University 亜鉛欠乏性味覚異常検査法
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
JP2009533065A (ja) 2006-04-20 2009-09-17 ジボダン エス エー 味覚物質同定のための機能的方法
EP2047254B1 (en) 2006-04-20 2015-10-28 Givaudan SA Method relating to sweetness enhancement
JP2010514411A (ja) * 2006-09-05 2010-05-06 セノミクス・インコーポレーテッド ヒトＴ２Ｒ受容体ｈＴ２Ｒ５０の新規ハプロタイプおよびヒト苦味モジュレータを同定するためのアッセイにおけるその使用
KR101511394B1 (ko) 2007-01-18 2015-04-10 지보당 에스아 키메라 우마미 미각 수용체, 이를 코딩하는 핵산 및 이의 용도
EP2137322B1 (en) 2007-03-30 2013-02-27 Givaudan SA Methods to identify tas2r modulators
EP2164976A4 (en) 2007-06-08 2010-06-30 Senomyx Inc THEORETICAL BASIS, METHODS AND TESTS FOR IDENTIFYING FLAVOR SPECIES OF HUMAN AND NON-MUSCLE PRIMATES AND USE THEREOF IN TASTE MODULATOR AND THERAPEUTIC SCREENING TESTS
WO2009025793A2 (en) 2007-08-21 2009-02-26 Senomyx, Inc. Human t2r bitterness receptors and uses thereof
CA2713885A1 (en) * 2008-02-01 2009-08-20 Chromocell Corporation Novel cell lines and methods
US20130115624A1 (en) 2010-05-07 2013-05-09 Givaudan S.A. Methods To Identify Modulators
EP2567231A1 (en) 2010-05-07 2013-03-13 Givaudan SA Methods to identify modulators of tas2r4s receptors
WO2011160093A2 (en) * 2010-06-17 2011-12-22 California Institute Of Technology Methods and systems for modulating hormones and related methods, agents and compositions
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
WO2013159227A1 (en) * 2012-04-25 2013-10-31 University Of Manitoba Bitter taste receptor constitutively active mutants
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
ES2797547T3 (es) 2013-03-15 2020-12-02 Applied Food Biotech Inc Receptores del sabor amargo felino y métodos.
US10107794B2 (en) 2013-05-10 2018-10-23 Pepsico, Inc. Methods of using U2-OS cells to identify potential sweet taste modulators
MX384586B (es) * 2013-05-10 2025-03-14 Pepsico Inc Ensayo de internalización del receptor del gusto.
ES2802376T3 (es) 2014-02-12 2021-01-19 Firmenich Incorporated Procedimiento mejorado para la síntesis de 1-bencil-3-(1-(isoxazol-4-ilmetil)-1h-pirazol-4-il)imidazolidin-2,4-dionas sustituidas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016178A2 (en) 1992-02-12 1993-08-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Sequences characteristic of human gene transcription product
CN1155714C (zh) 1996-09-04 2004-06-30 辛根塔默根有限公司 抗真菌蛋白及其编码dna和掺入此dna的宿主
AU2685599A (en) 1998-02-18 1999-09-06 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
WO2000038536A2 (en) 1998-12-23 2000-07-06 Mount Sinai School Of Medicine Of New York University Inhibitors of the bitter taste response
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
WO2001018050A2 (en) 1999-09-10 2001-03-15 The Regents Of The University Of California T2r taste receptor family

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