JP2003510037A5 - - Google Patents

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Publication number
JP2003510037A5
JP2003510037A5 JP2001522272A JP2001522272A JP2003510037A5 JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5 JP 2001522272 A JP2001522272 A JP 2001522272A JP 2001522272 A JP2001522272 A JP 2001522272A JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5
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JP
Japan
Prior art keywords
seq
polypeptide
nucleic acid
sequence
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001522272A
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English (en)
Japanese (ja)
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JP4339542B2 (ja
JP2003510037A (ja
Filing date
Publication date
Priority claimed from US09/393,634 external-priority patent/US6558910B2/en
Application filed filed Critical
Priority claimed from PCT/US2000/024821 external-priority patent/WO2001018050A2/en
Publication of JP2003510037A publication Critical patent/JP2003510037A/ja
Publication of JP2003510037A5 publication Critical patent/JP2003510037A5/ja
Application granted granted Critical
Publication of JP4339542B2 publication Critical patent/JP4339542B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001522272A 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー Expired - Fee Related JP4339542B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/393,634 US6558910B2 (en) 1999-09-10 1999-09-10 SF, a novel family of taste receptors
US09/393,634 1999-09-10
US09/510,332 US7244584B2 (en) 1999-09-10 2000-02-22 T2R, a novel family of taste receptors
US09/510,332 2000-02-22
PCT/US2000/024821 WO2001018050A2 (en) 1999-09-10 2000-09-08 T2r taste receptor family

Publications (3)

Publication Number Publication Date
JP2003510037A JP2003510037A (ja) 2003-03-18
JP2003510037A5 true JP2003510037A5 (enExample) 2007-09-06
JP4339542B2 JP4339542B2 (ja) 2009-10-07

Family

ID=27014384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001522272A Expired - Fee Related JP4339542B2 (ja) 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー

Country Status (10)

Country Link
US (8) US7465550B2 (enExample)
EP (1) EP1214343A2 (enExample)
JP (1) JP4339542B2 (enExample)
CN (1) CN1289525C (enExample)
AU (2) AU773600B2 (enExample)
CA (1) CA2384777A1 (enExample)
IL (1) IL148593A0 (enExample)
MX (1) MXPA02002538A (enExample)
NO (1) NO20021164L (enExample)
WO (1) WO2001018050A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4339542B2 (ja) 1999-09-10 2009-10-07 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア Ｔ２ｒ、すなわち味覚受容体の新規ファミリー
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
JP2003530098A (ja) 2000-04-07 2003-10-14 セノミックス、インコーポレイテッド Ｔ２ｒ味覚受容体及びそれをコードする遺伝子
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US8030008B2 (en) 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
CN100489102C (zh) 2001-06-26 2009-05-20 塞诺米克斯公司 T1r异源寡聚的味觉受体和表达所述受体的细胞系及其在鉴定味觉化合物中的用途
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
JP4551656B2 (ja) * 2001-07-10 2010-09-29 セノミックス インコーポレイテッド 苦味を阻止する化合物を同定するための特異的ｔ２ｒ味覚受容体の使用
US7314725B2 (en) 2001-07-20 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Phenylthiocarbamide (PTC) taste receptor
JP2005522187A (ja) * 2001-10-12 2005-07-28 ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア サン ディエゴ 胃腸化学感覚受容体
AU2003261280B2 (en) 2002-07-29 2009-02-05 Senomyx, Inc. Identification of a novel bitter taste receptor, T2R76
EP2270156A3 (en) * 2002-09-25 2011-08-10 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
WO2004055048A2 (en) 2002-12-18 2004-07-01 Givaudan Sa Chimeric alpha q-gustducin g-proteins
CA2534027A1 (en) 2003-06-19 2005-01-27 Dennis Drayna Variants of human taste receptor genes
WO2006053771A2 (en) 2004-11-18 2006-05-26 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts Agonists of bitter taste receptors and uses thereof
JP2008537473A (ja) 2005-02-08 2008-09-18 セノミクス・インコーポレーテッド アセトアミノフェン、ラニチジン、ストリキニーネおよびデナトニウムのｐヒトＴ２Ｒ受容体、ならびにヒト苦味調節剤を同定するための関連アッセイ
EP1970452A4 (en) 2005-12-27 2009-06-17 Univ Nihon METHOD FOR STUDYING TASTE DISTURBANCE WITH ZINC
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
EP2047254B1 (en) 2006-04-20 2015-10-28 Givaudan SA Method relating to sweetness enhancement
WO2007121599A1 (en) 2006-04-20 2007-11-01 Givaudan Sa Functional method to identify tastants
US7811788B2 (en) * 2006-09-05 2010-10-12 Senomyx Inc. Nucleic acid encoding a haplotype of human T2R receptor hT2R50
KR101511394B1 (ko) 2007-01-18 2015-04-10 지보당 에스아 키메라 우마미 미각 수용체, 이를 코딩하는 핵산 및 이의 용도
JP5465656B2 (ja) 2007-03-30 2014-04-09 ジボダン エス エー 調節物質を同定するための方法
WO2008153924A2 (en) * 2007-06-08 2008-12-18 Senomyx, Inc. Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays
RU2522456C2 (ru) 2007-08-21 2014-07-10 Синомикс, Инк. Соединения, ингибирующие (блокирующие) горький вкус, способы их применения и получения
WO2009102569A2 (en) * 2008-02-01 2009-08-20 Chromocell Corporation Novel cell lines and methods
WO2011138455A1 (en) 2010-05-07 2011-11-10 Givaudan Sa Methods to identify modulators
EP2567231A1 (en) 2010-05-07 2013-03-13 Givaudan SA Methods to identify modulators of tas2r4s receptors
WO2011160093A2 (en) 2010-06-17 2011-12-22 California Institute Of Technology Methods and systems for modulating hormones and related methods, agents and compositions
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
WO2013159227A1 (en) * 2012-04-25 2013-10-31 University Of Manitoba Bitter taste receptor constitutively active mutants
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
US9603379B2 (en) 2013-03-15 2017-03-28 Applied Food Biotechnology, Inc Feline bitter taste receptors and methods
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
MX384586B (es) * 2013-05-10 2025-03-14 Pepsico Inc Ensayo de internalización del receptor del gusto.
EP2994477A4 (en) 2013-05-10 2017-03-22 Pepsico, Inc. Cells as a model to identify potential taste modulators
ES2802376T3 (es) 2014-02-12 2021-01-19 Firmenich Incorporated Procedimiento mejorado para la síntesis de 1-bencil-3-(1-(isoxazol-4-ilmetil)-1h-pirazol-4-il)imidazolidin-2,4-dionas sustituidas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3665893A (en) 1992-02-12 1993-09-03 United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Sequences characteristic of human gene transcription product
BR9711291A (pt) 1996-09-04 2002-01-22 Mogen Int Proteìnas anti-fúngicas, codificação de dna para as mesmas e hospedeiros que incorporam as mesmas
CA2320799A1 (en) 1998-02-18 1999-08-26 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
EP1139793B1 (en) 1998-12-23 2009-10-14 Mount Sinai School of Medicine of New York University Inhibitors of the bitter taste response
JP4339542B2 (ja) 1999-09-10 2009-10-07 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア Ｔ２ｒ、すなわち味覚受容体の新規ファミリー
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors

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