JP2007507544A5 - - Google Patents
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- Publication number
- JP2007507544A5 JP2007507544A5 JP2006534237A JP2006534237A JP2007507544A5 JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5 JP 2006534237 A JP2006534237 A JP 2006534237A JP 2006534237 A JP2006534237 A JP 2006534237A JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- cell
- compound
- functional effect
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 20
- 230000000694 effects Effects 0.000 claims 12
- 102000005962 receptors Human genes 0.000 claims 9
- 108020003175 receptors Proteins 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 101000659767 Homo sapiens Taste receptor type 1 member 1 Proteins 0.000 claims 2
- 101000659765 Homo sapiens Taste receptor type 1 member 2 Proteins 0.000 claims 2
- 101000659774 Homo sapiens Taste receptor type 1 member 3 Proteins 0.000 claims 2
- 102100035941 Taste receptor type 1 member 1 Human genes 0.000 claims 2
- 102100035948 Taste receptor type 1 member 2 Human genes 0.000 claims 2
- 102100035942 Taste receptor type 1 member 3 Human genes 0.000 claims 2
- 108091005708 gustatory receptors Proteins 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000000704 physical effect Effects 0.000 claims 2
- 101100004408 Arabidopsis thaliana BIG gene Proteins 0.000 claims 1
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 claims 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 claims 1
- 101100206901 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) TIR3 gene Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000002925 chemical effect Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/679,102 US20050106571A1 (en) | 2003-10-02 | 2003-10-02 | Mammalian T1R3 sweet taste receptors |
| PCT/US2004/032678 WO2005033125A2 (en) | 2003-10-02 | 2004-10-04 | Mammalian t1r3 sweet taste receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007507544A JP2007507544A (ja) | 2007-03-29 |
| JP2007507544A5 true JP2007507544A5 (enExample) | 2008-05-15 |
Family
ID=34422153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534237A Pending JP2007507544A (ja) | 2003-10-02 | 2004-10-04 | 哺乳動物ｔ１ｒ３甘味レセプター |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050106571A1 (enExample) |
| EP (1) | EP1684789A4 (enExample) |
| JP (1) | JP2007507544A (enExample) |
| AU (1) | AU2004278425A1 (enExample) |
| CA (1) | CA2540837A1 (enExample) |
| WO (1) | WO2005033125A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| CA2408140A1 (en) * | 2000-05-22 | 2001-11-29 | Incyte Genomics, Inc. | G-protein coupled receptors |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US20080244761A1 (en) * | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| WO2006113422A2 (en) * | 2005-04-13 | 2006-10-26 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| DE602006012460D1 (de) | 2006-06-07 | 2010-04-08 | Nutrinova Gmbh | Verfahren zum Screening von Substanzen die die Aktivität von Gpcrs modulieren |
| JP2009544332A (ja) * | 2006-07-27 | 2009-12-17 | ザ・コカ−コーラ・カンパニー | 味覚調節物質を同定するためのモデル味覚細胞および使用方法 |
| EP3034083B1 (en) * | 2006-09-21 | 2020-12-09 | University of Rochester | Antisense oligonucleotides for use in treating myotonic dystrophy |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| NZ586957A (en) * | 2008-02-01 | 2014-03-28 | Chromocell Corp | Cell lines and methods for making and using them |
| SG177252A1 (en) | 2008-12-01 | 2012-03-29 | Lab Corp America Holdings | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 |
| SG172983A1 (en) | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
| JP2012515353A (ja) * | 2009-01-15 | 2012-07-05 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Ｈｅｒ−２発現の測定による患者の反応を判定する方法 |
| EP2742350B1 (en) | 2011-08-08 | 2019-10-30 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| RU2665812C2 (ru) | 2013-05-10 | 2018-09-04 | Пепсико, Инк. | Метод анализа интернализации вкусовых рецепторов |
| CN111973155B (zh) * | 2020-08-23 | 2023-06-16 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020061522A1 (en) | 2000-02-29 | 2002-05-23 | Glucksmann Maria Alexandra | 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor |
| CN1178952C (zh) | 1998-07-28 | 2004-12-08 | 加利福尼亚大学董事会 | 编码与感觉转导有关的g-蛋白偶联受体的核酸 |
| US7402400B2 (en) | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| TW201006846A (en) * | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| CA2406999A1 (en) | 2000-04-28 | 2001-11-08 | Warner-Lambert Company | Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| EP1572871A4 (en) * | 2001-04-20 | 2007-11-14 | Sinai School Medicine | T1R3, A NEW TASTE RECEPTOR |
| JP3698069B2 (ja) * | 2001-05-01 | 2005-09-21 | 独立行政法人食品総合研究所 | 新規遺伝子 |
| US20030143668A1 (en) | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
| EP2003451B1 (en) | 2001-06-26 | 2012-05-30 | Senomyx, Inc. | T1r1-t1r3 hetero-oligomeric umami taste receptors and cell lines that express said receptors and use thereof for identification of umami taste compounds |
| WO2003025137A2 (en) | 2001-09-18 | 2003-03-27 | Irm, Llc | Sweet taste receptors |
-
2003
- 2003-10-02 US US10/679,102 patent/US20050106571A1/en not_active Abandoned
-
2004
- 2004-10-04 CA CA002540837A patent/CA2540837A1/en not_active Abandoned
- 2004-10-04 EP EP04794142A patent/EP1684789A4/en not_active Ceased
- 2004-10-04 JP JP2006534237A patent/JP2007507544A/ja active Pending
- 2004-10-04 WO PCT/US2004/032678 patent/WO2005033125A2/en not_active Ceased
- 2004-10-04 AU AU2004278425A patent/AU2004278425A1/en not_active Abandoned
-
2006
- 2006-04-10 US US11/402,202 patent/US7459277B2/en not_active Expired - Lifetime
-
2008
- 2008-10-23 US US12/257,290 patent/US7939279B2/en not_active Expired - Lifetime
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