JP2007507544A5 - - Google Patents
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- JP2007507544A5 JP2007507544A5 JP2006534237A JP2006534237A JP2007507544A5 JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5 JP 2006534237 A JP2006534237 A JP 2006534237A JP 2006534237 A JP2006534237 A JP 2006534237A JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- cell
- compound
- functional effect
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 20
- 230000000694 effects Effects 0.000 claims 12
- 102000005962 receptors Human genes 0.000 claims 9
- 108020003175 receptors Proteins 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 101000659767 Homo sapiens Taste receptor type 1 member 1 Proteins 0.000 claims 2
- 101000659765 Homo sapiens Taste receptor type 1 member 2 Proteins 0.000 claims 2
- 101000659774 Homo sapiens Taste receptor type 1 member 3 Proteins 0.000 claims 2
- 102100035941 Taste receptor type 1 member 1 Human genes 0.000 claims 2
- 102100035948 Taste receptor type 1 member 2 Human genes 0.000 claims 2
- 102100035942 Taste receptor type 1 member 3 Human genes 0.000 claims 2
- 108091005708 gustatory receptors Proteins 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000000704 physical effect Effects 0.000 claims 2
- 101100004408 Arabidopsis thaliana BIG gene Proteins 0.000 claims 1
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 claims 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 claims 1
- 101100206901 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) TIR3 gene Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000002925 chemical effect Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/679,102 US20050106571A1 (en) | 2003-10-02 | 2003-10-02 | Mammalian T1R3 sweet taste receptors |
| PCT/US2004/032678 WO2005033125A2 (en) | 2003-10-02 | 2004-10-04 | Mammalian t1r3 sweet taste receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007507544A JP2007507544A (ja) | 2007-03-29 |
| JP2007507544A5 true JP2007507544A5 (enExample) | 2008-05-15 |
Family
ID=34422153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534237A Pending JP2007507544A (ja) | 2003-10-02 | 2004-10-04 | 哺乳動物ｔ１ｒ３甘味レセプター |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050106571A1 (enExample) |
| EP (1) | EP1684789A4 (enExample) |
| JP (1) | JP2007507544A (enExample) |
| AU (1) | AU2004278425A1 (enExample) |
| CA (1) | CA2540837A1 (enExample) |
| WO (1) | WO2005033125A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| CA2408140A1 (en) * | 2000-05-22 | 2001-11-29 | Incyte Genomics, Inc. | G-protein coupled receptors |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US20080244761A1 (en) * | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| DK1865316T3 (da) | 2006-06-07 | 2010-05-25 | Nutrinova Gmbh | Fremgangsmåde til screening af forbindelser, der modulerer aktiviteten af G-protein-koblede receptorer |
| CN101495508A (zh) * | 2006-07-27 | 2009-07-29 | 可口可乐公司 | 用于鉴定味觉调节剂的模式味觉细胞和方法 |
| JP5926475B2 (ja) * | 2006-09-21 | 2016-05-25 | ユニバーシティー オブ ロチェスター | 筋緊張性ジストロフィーのためのタンパク質置換治療に関する組成物および方法 |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| KR20100122491A (ko) * | 2008-02-01 | 2010-11-22 | 크로모셀 코포레이션 | 세포주 및 이의 제조 및 사용 방법 |
| ES2637411T3 (es) | 2008-12-01 | 2017-10-13 | Laboratory Corporation Of America Holdings | Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95 |
| SG172983A1 (en) | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
| CA2749817A1 (en) * | 2009-01-15 | 2010-07-22 | Laboratory Corporation Of America Holdings | Methods of determining patient response by measurement of her-2 expression |
| EP2742350B1 (en) | 2011-08-08 | 2019-10-30 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| PL2994482T3 (pl) | 2013-05-10 | 2020-06-01 | Pepsico, Inc. | Test internalizacji receptora smaku |
| CN111973155B (zh) * | 2020-08-23 | 2023-06-16 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020061522A1 (en) | 2000-02-29 | 2002-05-23 | Glucksmann Maria Alexandra | 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor |
| US7402400B2 (en) * | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| AU764180B2 (en) | 1998-07-28 | 2003-08-14 | Regents Of The University Of California, The | Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| EP1280899A2 (en) | 2000-04-28 | 2003-02-05 | Warner-Lambert Company | Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| CA2445197A1 (en) * | 2001-04-20 | 2002-10-31 | Mount Sinai School Of Medicine | T1r3 a novel taste receptor |
| JP3698069B2 (ja) * | 2001-05-01 | 2005-09-21 | 独立行政法人食品総合研究所 | 新規遺伝子 |
| US20030143668A1 (en) | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
| WO2003001876A2 (en) | 2001-06-26 | 2003-01-09 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| AU2002336571A1 (en) | 2001-09-18 | 2003-04-01 | Irm, Llc | Sweet taste receptors |
-
2003
- 2003-10-02 US US10/679,102 patent/US20050106571A1/en not_active Abandoned
-
2004
- 2004-10-04 JP JP2006534237A patent/JP2007507544A/ja active Pending
- 2004-10-04 WO PCT/US2004/032678 patent/WO2005033125A2/en not_active Ceased
- 2004-10-04 AU AU2004278425A patent/AU2004278425A1/en not_active Abandoned
- 2004-10-04 CA CA002540837A patent/CA2540837A1/en not_active Abandoned
- 2004-10-04 EP EP04794142A patent/EP1684789A4/en not_active Ceased
-
2006
- 2006-04-10 US US11/402,202 patent/US7459277B2/en not_active Expired - Lifetime
-
2008
- 2008-10-23 US US12/257,290 patent/US7939279B2/en not_active Expired - Lifetime
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