JP2007507544A5 - - Google Patents
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- Publication number
- JP2007507544A5 JP2007507544A5 JP2006534237A JP2006534237A JP2007507544A5 JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5 JP 2006534237 A JP2006534237 A JP 2006534237A JP 2006534237 A JP2006534237 A JP 2006534237A JP 2007507544 A5 JP2007507544 A5 JP 2007507544A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- cell
- compound
- functional effect
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 20
- 230000000694 effects Effects 0.000 claims 12
- 102000005962 receptors Human genes 0.000 claims 9
- 108020003175 receptors Proteins 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 101000659767 Homo sapiens Taste receptor type 1 member 1 Proteins 0.000 claims 2
- 101000659765 Homo sapiens Taste receptor type 1 member 2 Proteins 0.000 claims 2
- 101000659774 Homo sapiens Taste receptor type 1 member 3 Proteins 0.000 claims 2
- 102100035941 Taste receptor type 1 member 1 Human genes 0.000 claims 2
- 102100035948 Taste receptor type 1 member 2 Human genes 0.000 claims 2
- 102100035942 Taste receptor type 1 member 3 Human genes 0.000 claims 2
- 108091005708 gustatory receptors Proteins 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000000704 physical effect Effects 0.000 claims 2
- 101100004408 Arabidopsis thaliana BIG gene Proteins 0.000 claims 1
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 claims 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 claims 1
- 101100206901 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) TIR3 gene Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000002925 chemical effect Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/679,102 US20050106571A1 (en) | 2003-10-02 | 2003-10-02 | Mammalian T1R3 sweet taste receptors |
| PCT/US2004/032678 WO2005033125A2 (en) | 2003-10-02 | 2004-10-04 | Mammalian t1r3 sweet taste receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007507544A JP2007507544A (ja) | 2007-03-29 |
| JP2007507544A5 true JP2007507544A5 (enExample) | 2008-05-15 |
Family
ID=34422153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534237A Pending JP2007507544A (ja) | 2003-10-02 | 2004-10-04 | 哺乳動物ｔ１ｒ３甘味レセプター |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050106571A1 (enExample) |
| EP (1) | EP1684789A4 (enExample) |
| JP (1) | JP2007507544A (enExample) |
| AU (1) | AU2004278425A1 (enExample) |
| CA (1) | CA2540837A1 (enExample) |
| WO (1) | WO2005033125A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| JP2004515215A (ja) * | 2000-05-22 | 2004-05-27 | インサイト・ゲノミックス・インコーポレイテッド | Ｇタンパク質結合受容体 |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US20080244761A1 (en) * | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| ATE458998T1 (de) | 2006-06-07 | 2010-03-15 | Nutrinova Gmbh | Verfahren zum screening von substanzen die die aktivität von gpcrs modulieren |
| EP2046829A4 (en) * | 2006-07-27 | 2010-05-12 | Coca Cola Co | MODEL TASTE CELLS AND METHODS OF USING SAME FOR IDENTIFYING MODULATORS OF TASTE SENSATION |
| EP3034083B1 (en) * | 2006-09-21 | 2020-12-09 | University of Rochester | Antisense oligonucleotides for use in treating myotonic dystrophy |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| AU2009215106B2 (en) * | 2008-02-01 | 2015-07-23 | Chromocell Corporation | Cell lines and methods for making and using them |
| ES2637411T3 (es) | 2008-12-01 | 2017-10-13 | Laboratory Corporation Of America Holdings | Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95 |
| CA2749846C (en) | 2009-01-15 | 2018-08-07 | Laboratory Corporation Of America Holdings | Methods of determining patient response by measurement of her-3 |
| WO2010083463A1 (en) * | 2009-01-15 | 2010-07-22 | Laboratory Corporation Of America Holdings | Methods of determining patient response by measurement of her-2 expression |
| EP2742350B1 (en) | 2011-08-08 | 2019-10-30 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| RU2665812C2 (ru) | 2013-05-10 | 2018-09-04 | Пепсико, Инк. | Метод анализа интернализации вкусовых рецепторов |
| CN111973155B (zh) * | 2020-08-23 | 2023-06-16 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020061522A1 (en) | 2000-02-29 | 2002-05-23 | Glucksmann Maria Alexandra | 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor |
| US6383778B1 (en) | 1998-07-28 | 2002-05-07 | The Regents Of The University Of California | Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction |
| US7402400B2 (en) | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| AU2001255681A1 (en) | 2000-04-28 | 2001-11-12 | The Monell Chemical Senses Center | Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US20040219632A1 (en) * | 2001-04-20 | 2004-11-04 | Robert Margolskee | T1r3 a novel taste receptor |
| JP3698069B2 (ja) * | 2001-05-01 | 2005-09-21 | 独立行政法人食品総合研究所 | 新規遺伝子 |
| US20030143668A1 (en) | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
| CN100489102C (zh) | 2001-06-26 | 2009-05-20 | 塞诺米克斯公司 | T1r异源寡聚的味觉受体和表达所述受体的细胞系及其在鉴定味觉化合物中的用途 |
| WO2003025137A2 (en) | 2001-09-18 | 2003-03-27 | Irm, Llc | Sweet taste receptors |
-
2003
- 2003-10-02 US US10/679,102 patent/US20050106571A1/en not_active Abandoned
-
2004
- 2004-10-04 WO PCT/US2004/032678 patent/WO2005033125A2/en not_active Ceased
- 2004-10-04 AU AU2004278425A patent/AU2004278425A1/en not_active Abandoned
- 2004-10-04 JP JP2006534237A patent/JP2007507544A/ja active Pending
- 2004-10-04 EP EP04794142A patent/EP1684789A4/en not_active Ceased
- 2004-10-04 CA CA002540837A patent/CA2540837A1/en not_active Abandoned
-
2006
- 2006-04-10 US US11/402,202 patent/US7459277B2/en not_active Expired - Lifetime
-
2008
- 2008-10-23 US US12/257,290 patent/US7939279B2/en not_active Expired - Lifetime
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