JP2007507544A - 哺乳動物ｔ１ｒ３甘味レセプター - Google Patents

哺乳動物ｔ１ｒ３甘味レセプター Download PDF

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Publication number
JP2007507544A
JP2007507544A JP2006534237A JP2006534237A JP2007507544A JP 2007507544 A JP2007507544 A JP 2007507544A JP 2006534237 A JP2006534237 A JP 2006534237A JP 2006534237 A JP2006534237 A JP 2006534237A JP 2007507544 A JP2007507544 A JP 2007507544A
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JP
Japan
Prior art keywords
seq
receptor
taste
polypeptide
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006534237A
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English (en)
Japanese (ja)
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JP2007507544A5 (enExample
Inventor
イゾルデ エルレンバッハ，
ニコラス ジェイ． ピー． ルイバ，
グレイス チャオ，
チャールズ エス． ズーカー，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
US Department of Health and Human Services
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University of California
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by University of California, US Department of Health and Human Services filed Critical University of California
Publication of JP2007507544A publication Critical patent/JP2007507544A/ja
Publication of JP2007507544A5 publication Critical patent/JP2007507544A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2006534237A 2003-10-02 2004-10-04 哺乳動物ｔ１ｒ３甘味レセプター Pending JP2007507544A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/679,102 US20050106571A1 (en) 2003-10-02 2003-10-02 Mammalian T1R3 sweet taste receptors
PCT/US2004/032678 WO2005033125A2 (en) 2003-10-02 2004-10-04 Mammalian t1r3 sweet taste receptors

Publications (2)

Publication Number Publication Date
JP2007507544A true JP2007507544A (ja) 2007-03-29
JP2007507544A5 JP2007507544A5 (enExample) 2008-05-15

Family

ID=34422153

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006534237A Pending JP2007507544A (ja) 2003-10-02 2004-10-04 哺乳動物ｔ１ｒ３甘味レセプター

Country Status (6)

Country Link
US (3) US20050106571A1 (enExample)
EP (1) EP1684789A4 (enExample)
JP (1) JP2007507544A (enExample)
AU (1) AU2004278425A1 (enExample)
CA (1) CA2540837A1 (enExample)
WO (1) WO2005033125A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
CA2408140A1 (en) * 2000-05-22 2001-11-29 Incyte Genomics, Inc. G-protein coupled receptors
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
DK1865316T3 (da) 2006-06-07 2010-05-25 Nutrinova Gmbh Fremgangsmåde til screening af forbindelser, der modulerer aktiviteten af G-protein-koblede receptorer
CN101495508A (zh) * 2006-07-27 2009-07-29 可口可乐公司 用于鉴定味觉调节剂的模式味觉细胞和方法
JP5926475B2 (ja) * 2006-09-21 2016-05-25 ユニバーシティー オブ ロチェスター 筋緊張性ジストロフィーのためのタンパク質置換治療に関する組成物および方法
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
KR20100122491A (ko) * 2008-02-01 2010-11-22 크로모셀 코포레이션 세포주 및 이의 제조 및 사용 방법
ES2637411T3 (es) 2008-12-01 2017-10-13 Laboratory Corporation Of America Holdings Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95
SG172983A1 (en) 2009-01-15 2011-08-29 Lab Corp America Holdings Methods of determining patient response by measurement of her-3
CA2749817A1 (en) * 2009-01-15 2010-07-22 Laboratory Corporation Of America Holdings Methods of determining patient response by measurement of her-2 expression
EP2742350B1 (en) 2011-08-08 2019-10-30 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
PL2994482T3 (pl) 2013-05-10 2020-06-01 Pepsico, Inc. Test internalizacji receptora smaku
CN111973155B (zh) * 2020-08-23 2023-06-16 吾征智能技术(北京)有限公司 一种基于人体口味异常变化的疾病认知自学习系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160424A1 (en) * 2001-03-30 2002-10-31 Adler Jon Elliot T1R hetero-oligomeric taste receptors
WO2002086079A2 (en) * 2001-04-20 2002-10-31 Mount Sinai School Of Medicine T1r3 a novel taste receptor
JP2002355044A (ja) * 2001-05-01 2002-12-10 National Food Research Institute 新規遺伝子

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020061522A1 (en) 2000-02-29 2002-05-23 Glucksmann Maria Alexandra 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor
US7402400B2 (en) * 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
AU764180B2 (en) 1998-07-28 2003-08-14 Regents Of The University Of California, The Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
EP1280899A2 (en) 2000-04-28 2003-02-05 Warner-Lambert Company Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US20030143668A1 (en) 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors
WO2003001876A2 (en) 2001-06-26 2003-01-09 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
AU2002336571A1 (en) 2001-09-18 2003-04-01 Irm, Llc Sweet taste receptors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160424A1 (en) * 2001-03-30 2002-10-31 Adler Jon Elliot T1R hetero-oligomeric taste receptors
WO2002086079A2 (en) * 2001-04-20 2002-10-31 Mount Sinai School Of Medicine T1r3 a novel taste receptor
JP2002355044A (ja) * 2001-05-01 2002-12-10 National Food Research Institute 新規遺伝子

Also Published As

Publication number Publication date
EP1684789A4 (en) 2006-12-27
WO2005033125A3 (en) 2006-03-23
CA2540837A1 (en) 2005-04-14
AU2004278425A1 (en) 2005-04-14
US20050106571A1 (en) 2005-05-19
US7459277B2 (en) 2008-12-02
US20070105159A1 (en) 2007-05-10
EP1684789A2 (en) 2006-08-02
US20090155819A1 (en) 2009-06-18
US7939279B2 (en) 2011-05-10
WO2005033125A2 (en) 2005-04-14

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