CA2540837A1 - Mammalian t1r3 sweet taste receptors - Google Patents

Mammalian t1r3 sweet taste receptors Download PDF

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Publication number
CA2540837A1
CA2540837A1 CA002540837A CA2540837A CA2540837A1 CA 2540837 A1 CA2540837 A1 CA 2540837A1 CA 002540837 A CA002540837 A CA 002540837A CA 2540837 A CA2540837 A CA 2540837A CA 2540837 A1 CA2540837 A1 CA 2540837A1
Authority
CA
Canada
Prior art keywords
receptor
taste
cell
polypeptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002540837A
Other languages
English (en)
French (fr)
Inventor
Isolde Erlenbach
Nicholas J. P. Ryba
Grace Zhao
Charles S. Zuker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
US Department of Health and Human Services
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2540837A1 publication Critical patent/CA2540837A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002540837A 2003-10-02 2004-10-04 Mammalian t1r3 sweet taste receptors Abandoned CA2540837A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/679,102 US20050106571A1 (en) 2003-10-02 2003-10-02 Mammalian T1R3 sweet taste receptors
US10/679,102 2003-10-02
PCT/US2004/032678 WO2005033125A2 (en) 2003-10-02 2004-10-04 Mammalian t1r3 sweet taste receptors

Publications (1)

Publication Number Publication Date
CA2540837A1 true CA2540837A1 (en) 2005-04-14

Family

ID=34422153

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002540837A Abandoned CA2540837A1 (en) 2003-10-02 2004-10-04 Mammalian t1r3 sweet taste receptors

Country Status (6)

Country Link
US (3) US20050106571A1 (enExample)
EP (1) EP1684789A4 (enExample)
JP (1) JP2007507544A (enExample)
AU (1) AU2004278425A1 (enExample)
CA (1) CA2540837A1 (enExample)
WO (1) WO2005033125A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
CA2408140A1 (en) * 2000-05-22 2001-11-29 Incyte Genomics, Inc. G-protein coupled receptors
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
WO2006113422A2 (en) * 2005-04-13 2006-10-26 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Human sweet and umami taste receptor variants
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
DE602006012460D1 (de) 2006-06-07 2010-04-08 Nutrinova Gmbh Verfahren zum Screening von Substanzen die die Aktivität von Gpcrs modulieren
JP2009544332A (ja) * 2006-07-27 2009-12-17 ザ・コカ−コーラ・カンパニー 味覚調節物質を同定するためのモデル味覚細胞および使用方法
EP3034083B1 (en) * 2006-09-21 2020-12-09 University of Rochester Antisense oligonucleotides for use in treating myotonic dystrophy
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
NZ586957A (en) * 2008-02-01 2014-03-28 Chromocell Corp Cell lines and methods for making and using them
SG177252A1 (en) 2008-12-01 2012-03-29 Lab Corp America Holdings METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95
SG172983A1 (en) 2009-01-15 2011-08-29 Lab Corp America Holdings Methods of determining patient response by measurement of her-3
JP2012515353A (ja) * 2009-01-15 2012-07-05 ラボラトリー コーポレイション オブ アメリカ ホールディングス Her−2発現の測定による患者の反応を判定する方法
EP2742350B1 (en) 2011-08-08 2019-10-30 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
RU2665812C2 (ru) 2013-05-10 2018-09-04 Пепсико, Инк. Метод анализа интернализации вкусовых рецепторов
CN111973155B (zh) * 2020-08-23 2023-06-16 吾征智能技术(北京)有限公司 一种基于人体口味异常变化的疾病认知自学习系统

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020061522A1 (en) 2000-02-29 2002-05-23 Glucksmann Maria Alexandra 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor
CN1178952C (zh) 1998-07-28 2004-12-08 加利福尼亚大学董事会 编码与感觉转导有关的g-蛋白偶联受体的核酸
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
CA2406999A1 (en) 2000-04-28 2001-11-08 Warner-Lambert Company Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US6955887B2 (en) * 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
EP1572871A4 (en) * 2001-04-20 2007-11-14 Sinai School Medicine T1R3, A NEW TASTE RECEPTOR
JP3698069B2 (ja) * 2001-05-01 2005-09-21 独立行政法人食品総合研究所 新規遺伝子
US20030143668A1 (en) 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors
EP2003451B1 (en) 2001-06-26 2012-05-30 Senomyx, Inc. T1r1-t1r3 hetero-oligomeric umami taste receptors and cell lines that express said receptors and use thereof for identification of umami taste compounds
WO2003025137A2 (en) 2001-09-18 2003-03-27 Irm, Llc Sweet taste receptors

Also Published As

Publication number Publication date
WO2005033125A3 (en) 2006-03-23
US20070105159A1 (en) 2007-05-10
AU2004278425A1 (en) 2005-04-14
EP1684789A2 (en) 2006-08-02
WO2005033125A2 (en) 2005-04-14
EP1684789A4 (en) 2006-12-27
JP2007507544A (ja) 2007-03-29
US20090155819A1 (en) 2009-06-18
US20050106571A1 (en) 2005-05-19
US7939279B2 (en) 2011-05-10
US7459277B2 (en) 2008-12-02

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued