AU2004278425A1 - Mammalian T1R3 sweet taste receptors - Google Patents
Mammalian T1R3 sweet taste receptors Download PDFInfo
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- AU2004278425A1 AU2004278425A1 AU2004278425A AU2004278425A AU2004278425A1 AU 2004278425 A1 AU2004278425 A1 AU 2004278425A1 AU 2004278425 A AU2004278425 A AU 2004278425A AU 2004278425 A AU2004278425 A AU 2004278425A AU 2004278425 A1 AU2004278425 A1 AU 2004278425A1
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- 150000003505 terpenes Chemical class 0.000 description 1
- 208000002918 testicular germ cell tumor Diseases 0.000 description 1
- 101150024821 tetO gene Proteins 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- MPLHNVLQVRSVEE-UHFFFAOYSA-N texas red Chemical compound [O-]S(=O)(=O)C1=CC(S(Cl)(=O)=O)=CC=C1C(C1=CC=2CCCN3CCCC(C=23)=C1O1)=C2C1=C(CCC1)C3=[N+]1CCCC3=C2 MPLHNVLQVRSVEE-UHFFFAOYSA-N 0.000 description 1
- 210000001103 thalamus Anatomy 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 150000003568 thioethers Chemical class 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 230000001550 time effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000003151 transfection method Methods 0.000 description 1
- 239000012581 transferrin Substances 0.000 description 1
- 238000003146 transient transfection Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/679,102 US20050106571A1 (en) | 2003-10-02 | 2003-10-02 | Mammalian T1R3 sweet taste receptors |
| US10/679,102 | 2003-10-02 | ||
| PCT/US2004/032678 WO2005033125A2 (en) | 2003-10-02 | 2004-10-04 | Mammalian t1r3 sweet taste receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004278425A1 true AU2004278425A1 (en) | 2005-04-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004278425A Abandoned AU2004278425A1 (en) | 2003-10-02 | 2004-10-04 | Mammalian T1R3 sweet taste receptors |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050106571A1 (enExample) |
| EP (1) | EP1684789A4 (enExample) |
| JP (1) | JP2007507544A (enExample) |
| AU (1) | AU2004278425A1 (enExample) |
| CA (1) | CA2540837A1 (enExample) |
| WO (1) | WO2005033125A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973155A (zh) * | 2020-08-23 | 2020-11-24 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201006846A (en) * | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| EP1301595A2 (en) * | 2000-05-22 | 2003-04-16 | Incyte Genomics, Inc. | G-protein coupled receptors |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US20080244761A1 (en) * | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| DE602006012460D1 (de) | 2006-06-07 | 2010-04-08 | Nutrinova Gmbh | Verfahren zum Screening von Substanzen die die Aktivität von Gpcrs modulieren |
| WO2008014450A2 (en) * | 2006-07-27 | 2008-01-31 | The Coca-Cola Company | Model taste cells and methods of use for identifying modulators of taste sensation |
| EP2066812A4 (en) * | 2006-09-21 | 2010-04-28 | Univ Rochester | COMPOSITIONS AND METHODS RELATED TO PROTEIN SHIFT THERAPY FOR MYOTONE DYSTROPHY |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| CA2713885A1 (en) * | 2008-02-01 | 2009-08-20 | Chromocell Corporation | Novel cell lines and methods |
| WO2010065568A2 (en) | 2008-12-01 | 2010-06-10 | Laboratory Corporation Of America Holdings | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 |
| SG172983A1 (en) | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
| EP2387717B1 (en) * | 2009-01-15 | 2014-12-10 | Laboratory Corporation of America Holdings | Methods of determining patient response by measurement of her-2 expression |
| WO2013022948A1 (en) | 2011-08-08 | 2013-02-14 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| MX384586B (es) | 2013-05-10 | 2025-03-14 | Pepsico Inc | Ensayo de internalización del receptor del gusto. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020061522A1 (en) | 2000-02-29 | 2002-05-23 | Glucksmann Maria Alexandra | 1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor |
| US7402400B2 (en) * | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| AU764180B2 (en) | 1998-07-28 | 2003-08-14 | Regents Of The University Of California, The | Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| JP2003531614A (ja) | 2000-04-28 | 2003-10-28 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 炭水化物化合物および他の甘味物質の感知に関連する遺伝子および配列変異 |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| WO2002086079A2 (en) * | 2001-04-20 | 2002-10-31 | Mount Sinai School Of Medicine | T1r3 a novel taste receptor |
| JP3698069B2 (ja) * | 2001-05-01 | 2005-09-21 | 独立行政法人食品総合研究所 | 新規遺伝子 |
| US20030143668A1 (en) | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
| EP2327985B2 (en) | 2001-06-26 | 2019-08-21 | Senomyx, Inc. | T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| WO2003025137A2 (en) | 2001-09-18 | 2003-03-27 | Irm, Llc | Sweet taste receptors |
-
2003
- 2003-10-02 US US10/679,102 patent/US20050106571A1/en not_active Abandoned
-
2004
- 2004-10-04 AU AU2004278425A patent/AU2004278425A1/en not_active Abandoned
- 2004-10-04 JP JP2006534237A patent/JP2007507544A/ja active Pending
- 2004-10-04 CA CA002540837A patent/CA2540837A1/en not_active Abandoned
- 2004-10-04 WO PCT/US2004/032678 patent/WO2005033125A2/en not_active Ceased
- 2004-10-04 EP EP04794142A patent/EP1684789A4/en not_active Ceased
-
2006
- 2006-04-10 US US11/402,202 patent/US7459277B2/en not_active Expired - Lifetime
-
2008
- 2008-10-23 US US12/257,290 patent/US7939279B2/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973155A (zh) * | 2020-08-23 | 2020-11-24 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
| CN111973155B (zh) * | 2020-08-23 | 2023-06-16 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20070105159A1 (en) | 2007-05-10 |
| US20090155819A1 (en) | 2009-06-18 |
| CA2540837A1 (en) | 2005-04-14 |
| US7459277B2 (en) | 2008-12-02 |
| US20050106571A1 (en) | 2005-05-19 |
| JP2007507544A (ja) | 2007-03-29 |
| US7939279B2 (en) | 2011-05-10 |
| EP1684789A4 (en) | 2006-12-27 |
| WO2005033125A2 (en) | 2005-04-14 |
| EP1684789A2 (en) | 2006-08-02 |
| WO2005033125A3 (en) | 2006-03-23 |
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Legal Events
| Date | Code | Title | Description |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |