JP2006502738A5 - - Google Patents

Info

Publication number

JP2006502738A5

JP2006502738A5 JP2004551403A JP2004551403A JP2006502738A5 JP 2006502738 A5 JP2006502738 A5 JP 2006502738A5 JP 2004551403 A JP2004551403 A JP 2004551403A JP 2004551403 A JP2004551403 A JP 2004551403A JP 2006502738 A5 JP2006502738 A5 JP 2006502738A5

Authority

JP

Japan

Prior art keywords

oasl

peptide

seq

expression

protein

Prior art date

2003-05-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
• Discuss

• 102100035473 2'-5'-oligoadenylate synthase-like protein Human genes 0.000 claims 45
• 101000597360 Homo sapiens 2'-5'-oligoadenylate synthase-like protein Proteins 0.000 claims 45
• 108090000765 processed proteins & peptides Proteins 0.000 claims 39
• 108090000623 proteins and genes Proteins 0.000 claims 17
• 230000027455 binding Effects 0.000 claims 15
• 238000000034 method Methods 0.000 claims 15
• 102000004169 proteins and genes Human genes 0.000 claims 14
• 150000001875 compounds Chemical class 0.000 claims 13
• 108091033319 polynucleotide Proteins 0.000 claims 13
• 102000040430 polynucleotide Human genes 0.000 claims 13
• 239000002157 polynucleotide Substances 0.000 claims 13
• 241001465754 Metazoa Species 0.000 claims 12
• 229920001184 polypeptide Polymers 0.000 claims 12
• 102000004196 processed proteins & peptides Human genes 0.000 claims 12
• 230000000694 effects Effects 0.000 claims 11
• 210000004027 cell Anatomy 0.000 claims 10
• 230000009261 transgenic effect Effects 0.000 claims 7
• 230000029279 positive regulation of transcription, DNA-dependent Effects 0.000 claims 5
• 108020001507 fusion proteins Proteins 0.000 claims 4
• 102000037865 fusion proteins Human genes 0.000 claims 4
• 230000003993 interaction Effects 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 230000004913 activation Effects 0.000 claims 3
• 238000012258 culturing Methods 0.000 claims 3
• 210000003527 eukaryotic cell Anatomy 0.000 claims 3
• 239000012634 fragment Substances 0.000 claims 3
• 239000002773 nucleotide Substances 0.000 claims 3
• 125000003729 nucleotide group Chemical group 0.000 claims 3
• 238000012216 screening Methods 0.000 claims 3
• 238000013518 transcription Methods 0.000 claims 3
• 230000035897 transcription Effects 0.000 claims 3
• 230000004568 DNA-binding Effects 0.000 claims 2
• FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 230000015556 catabolic process Effects 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 238000006731 degradation reaction Methods 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 108020004999 messenger RNA Proteins 0.000 claims 2
• 210000001672 ovary Anatomy 0.000 claims 2
• 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 2
• 101100134747 Mus musculus Oas1d gene Proteins 0.000 claims 1
• 101100134752 Mus musculus Oas2 gene Proteins 0.000 claims 1
• 101100518043 Mus musculus Oas3 gene Proteins 0.000 claims 1
• 101100518045 Mus musculus Oasl1 gene Proteins 0.000 claims 1
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
• 241000283984 Rodentia Species 0.000 claims 1
• 230000000692 anti-sense effect Effects 0.000 claims 1
• 238000004113 cell culture Methods 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 230000035558 fertility Effects 0.000 claims 1
• 238000009396 hybridization Methods 0.000 claims 1
• 210000004408 hybridoma Anatomy 0.000 claims 1
• 230000036512 infertility Effects 0.000 claims 1
• 208000000509 infertility Diseases 0.000 claims 1
• 231100000535 infertility Toxicity 0.000 claims 1
• 150000007523 nucleic acids Chemical group 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 210000001236 prokaryotic cell Anatomy 0.000 claims 1
• 239000011780 sodium chloride Substances 0.000 claims 1