JP2005502344A5 - - Google Patents
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- Publication number
- JP2005502344A5 JP2005502344A5 JP2003523647A JP2003523647A JP2005502344A5 JP 2005502344 A5 JP2005502344 A5 JP 2005502344A5 JP 2003523647 A JP2003523647 A JP 2003523647A JP 2003523647 A JP2003523647 A JP 2003523647A JP 2005502344 A5 JP2005502344 A5 JP 2005502344A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- polynucleotide
- isolated
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 54
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 52
- 210000004027 cell Anatomy 0.000 claims description 9
- 229920001184 polypeptide Polymers 0.000 claims 50
- 108091033319 polynucleotide Proteins 0.000 claims 33
- 102000040430 polynucleotide Human genes 0.000 claims 33
- 239000002157 polynucleotide Substances 0.000 claims 33
- 150000001875 compounds Chemical class 0.000 claims 9
- 238000000670 ligand binding assay Methods 0.000 claims 9
- 230000001747 exhibiting effect Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000012528 membrane Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000012286 ELISA Assay Methods 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000010561 standard procedure Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 101000604540 Homo sapiens PRKCA-binding protein Proteins 0.000 description 1
- 102100038730 PRKCA-binding protein Human genes 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31511101P | 2001-08-27 | 2001-08-27 | |
| PCT/EP2002/009518 WO2003018798A2 (en) | 2001-08-27 | 2002-08-26 | G-protein coupled receptor and dna sequences thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005502344A JP2005502344A (ja) | 2005-01-27 |
| JP2005502344A5 true JP2005502344A5 (enExample) | 2006-01-05 |
Family
ID=23222935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003523647A Pending JP2005502344A (ja) | 2001-08-27 | 2002-08-26 | 新規ｇタンパク質共役受容体およびそのｄｎａ配列 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20050106659A1 (enExample) |
| EP (1) | EP1423519A2 (enExample) |
| JP (1) | JP2005502344A (enExample) |
| AU (1) | AU2002331181A1 (enExample) |
| WO (1) | WO2003018798A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| HUE069586T2 (hu) | 2010-10-01 | 2025-03-28 | Modernatx Inc | Módosított nukleozidok, nukleotidok és nukleinsavak, valamint ezek felhasználása |
| JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| DK3682905T3 (da) | 2011-10-03 | 2022-02-28 | Modernatx Inc | Modificerede nukleosider, nukleotider og nukleinsyrer og anvendelser deraf |
| HRP20220717T1 (hr) | 2011-12-16 | 2022-07-22 | Modernatx, Inc. | Modificirani pripravci mrna |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| JP6189415B2 (ja) | 2012-04-02 | 2017-08-30 | モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． | 細胞質および細胞骨格タンパク質の産生のための修飾ポリヌクレオチド |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| EP2922554B1 (en) | 2012-11-26 | 2022-02-23 | ModernaTX, Inc. | Terminally modified rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5011912A (en) * | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| US5541087A (en) * | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| AU1208200A (en) * | 1998-10-15 | 2000-05-01 | Genetics Institute Inc. | Secreted expressed sequence tags (sests) |
| AU782817B2 (en) * | 2000-02-04 | 2005-09-01 | Lexicon Pharmaceuticals, Inc. | Novel human G protein coupled receptor proteins and polynucleotides encoding the same |
| US20030078407A1 (en) * | 2000-10-19 | 2003-04-24 | Smith Kelli E. | DNA encoding orphan SNORF53 receptor |
-
2002
- 2002-08-26 JP JP2003523647A patent/JP2005502344A/ja active Pending
- 2002-08-26 US US10/485,006 patent/US20050106659A1/en not_active Abandoned
- 2002-08-26 AU AU2002331181A patent/AU2002331181A1/en not_active Abandoned
- 2002-08-26 WO PCT/EP2002/009518 patent/WO2003018798A2/en not_active Ceased
- 2002-08-26 EP EP02767430A patent/EP1423519A2/en not_active Ceased
-
2007
- 2007-06-13 US US11/762,237 patent/US20070238135A1/en not_active Abandoned
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