|
US5776093A
(en)
*
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
MXPA01011279A
(es)
*
|
1999-05-07 |
2002-07-02 |
Genentech Inc |
Tratamiento de enfermedades autoinmunes con antagonistas que se unene a los marcadores de superficie, de celulas b.
|
|
US8383081B2
(en)
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
|
CA2375912C
(en)
*
|
1999-06-09 |
2014-03-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
WO2001003734A1
(en)
*
|
1999-07-12 |
2001-01-18 |
Genentech, Inc. |
Blocking immune response to a foreign antigen using an antagonist which binds to cd20
|
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
US6451284B1
(en)
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
CA2396793A1
(en)
*
|
2000-02-16 |
2001-08-23 |
Genentech, Inc. |
Uses of agonists and antagonists to modulate activity of tnf-related molecules
|
|
CA2411102A1
(en)
*
|
2000-06-20 |
2001-12-27 |
Idec Pharmaceutical Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
CA2422076A1
(en)
*
|
2000-09-18 |
2002-03-21 |
Idec Pharmaceutical Corporation |
Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination
|
|
US20030133939A1
(en)
*
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
US7754208B2
(en)
*
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
WO2002079517A1
(en)
*
|
2001-03-29 |
2002-10-10 |
Cytokine Pharmasciences, Inc. |
Methods and compositions for using mhc class ii invariant chain polypeptide as a receptor for macrophage migration inhibitory factor
|
|
AU2003202093B2
(en)
*
|
2001-07-02 |
2010-05-13 |
Aimsco Limited |
Treatment of MS with goat serum
|
|
CA2452986C
(en)
*
|
2001-07-02 |
2011-11-01 |
Aimsco Limited |
Use of polyclonal anti-hiv goat serum as a therapeutic agent
|
|
BR0211614A
(pt)
*
|
2001-08-03 |
2006-10-31 |
Genentech Inc |
polipeptìdeo tacis e br3 e empregos dos mesmos
|
|
CA2461351C
(en)
*
|
2001-09-26 |
2014-08-05 |
Ira H. Pastan |
Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells
|
|
US7030126B2
(en)
|
2001-11-16 |
2006-04-18 |
Als Therapy Development Foundation, Inc. |
Use of polyamine analogs for amyotrophic lateral sclerosis
|
|
KR101033196B1
(ko)
*
|
2002-02-14 |
2011-05-09 |
이뮤노메딕스, 인코오포레이티드 |
항-ｃｄ20 항체 및 그 융합 단백질 및 이들의 이용방법
|
|
US8287864B2
(en)
|
2002-02-14 |
2012-10-16 |
Immunomedics, Inc. |
Structural variants of antibodies for improved therapeutic characteristics
|
|
US20040001828A1
(en)
|
2002-02-21 |
2004-01-01 |
Joseph Tuscano |
Treatment methods using anti-CD22 antibodies
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
|
AU2015201433B2
(en)
*
|
2002-03-01 |
2017-01-12 |
Immunomedics, Inc. |
Internalizing anti-cd74 antibodies and methods of use
|
|
US8361464B2
(en)
|
2002-03-01 |
2013-01-29 |
Immunomedics, Inc. |
Anthracycline-Antibody Conjugates for Cancer Therapy
|
|
CA2478011C
(en)
|
2002-03-01 |
2013-05-21 |
Immunomedics, Inc. |
Bispecific antibody point mutations for enhancing rate of clearance
|
|
AU2012216518B2
(en)
*
|
2002-03-01 |
2014-12-18 |
Immunomedics, Inc. |
Internalizing Anti-CD74 Antibodies and Methods of Use
|
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
|
KR101017732B1
(ko)
|
2002-03-01 |
2011-02-28 |
이뮤노메딕스, 인코오포레이티드 |
내재화 항-ｃｄ74 항체 및 그 이용방법
|
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
|
SI2371392T1
(sl)
*
|
2002-05-02 |
2015-10-30 |
Wyeth Holdings Llc |
Konjugati derivat-nosilec kaliheamicina
|
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
AU2015246156B2
(en)
*
|
2002-05-02 |
2017-06-29 |
Wyeth Holdings Llc. |
Calicheamicin derivative-carrier conjugates
|
|
CN1692127A
(zh)
*
|
2002-07-25 |
2005-11-02 |
健泰科生物技术公司 |
Taci抗体及其用途
|
|
CN101928344B
(zh)
|
2002-10-17 |
2014-08-13 |
根马布股份公司 |
抗cd20的人单克隆抗体
|
|
US8420086B2
(en)
*
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
|
EP3263596A1
(en)
|
2002-12-16 |
2018-01-03 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
US7534427B2
(en)
*
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
US20040202666A1
(en)
*
|
2003-01-24 |
2004-10-14 |
Immunomedics, Inc. |
Anti-cancer anthracycline drug-antibody conjugates
|
|
AU2011236095B2
(en)
*
|
2003-01-24 |
2013-08-01 |
Immunomedics, Inc. |
Anthracycline-antibody conjugates
|
|
EP1460088A1
(en)
*
|
2003-03-21 |
2004-09-22 |
Biotest AG |
Humanized anti-CD4 antibody with immunosuppressive properties
|
|
AU2007242919B8
(en)
*
|
2003-04-09 |
2011-11-10 |
F. Hoffmann-La Roche Ag |
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor
|
|
EP2062916A3
(en)
|
2003-04-09 |
2009-08-19 |
Genentech, Inc. |
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-Alpha inhibitor
|
|
CA2525251C
(en)
*
|
2003-05-09 |
2015-10-27 |
Duke University |
Cd20-specific antibodies and methods employing same
|
|
US20050163775A1
(en)
*
|
2003-06-05 |
2005-07-28 |
Genentech, Inc. |
Combination therapy for B cell disorders
|
|
PL1631313T3
(pl)
|
2003-06-05 |
2015-08-31 |
Genentech Inc |
Terapia skojarzona zaburzeń z komórek B
|
|
US7754209B2
(en)
|
2003-07-26 |
2010-07-13 |
Trubion Pharmaceuticals |
Binding constructs and methods for use thereof
|
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
EP2216342B1
(en)
|
2003-07-31 |
2015-04-22 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
US8147832B2
(en)
*
|
2003-08-14 |
2012-04-03 |
Merck Patent Gmbh |
CD20-binding polypeptide compositions and methods
|
|
KR20060132554A
(ko)
*
|
2003-08-29 |
2006-12-21 |
제넨테크, 인크. |
안과 질병의 항-ｃｄ２０ 치료
|
|
ES2672640T3
(es)
|
2003-11-05 |
2018-06-15 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
|
KR20060109494A
(ko)
*
|
2003-12-19 |
2006-10-20 |
제넨테크, 인크. |
자가면역 질환의 치료에 있어서 ｃｄ20의 검출
|
|
MXPA06006865A
(es)
*
|
2003-12-19 |
2006-08-23 |
Genentech Inc |
Deteccion de cd20 en rechazo de transplante.
|
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US8883160B2
(en)
*
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
WO2005103081A2
(en)
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
JP2007536246A
(ja)
*
|
2004-05-05 |
2007-12-13 |
ジェネンテック・インコーポレーテッド |
自己免疫疾患の予防法
|
|
KR20120064120A
(ko)
|
2004-06-01 |
2012-06-18 |
제넨테크, 인크. |
항체 약물 접합체 및 방법
|
|
TW201422238A
(zh)
*
|
2004-06-04 |
2014-06-16 |
Genentech Inc |
Ｃｄ２０抗體於治療多發性硬化症之用途及用於該用途之物品
|
|
EP1765400A2
(en)
*
|
2004-06-04 |
2007-03-28 |
Genentech, Inc. |
Method for treating lupus
|
|
CN101027100A
(zh)
*
|
2004-07-22 |
2007-08-29 |
健泰科生物技术公司 |
治疗干燥综合征的方法
|
|
PL1776384T3
(pl)
|
2004-08-04 |
2013-10-31 |
Mentrik Biotech Llc |
WARIANTY REGIONÓW Fc
|
|
CA2580271A1
(en)
*
|
2004-10-05 |
2006-04-20 |
Genentech, Inc. |
Method for treating vasculitis
|
|
GT200500283A
(es)
*
|
2004-10-08 |
2006-05-08 |
|
Inmunoterapia de desordenes autoinmunes
|
|
ZA200705459B
(en)
*
|
2005-01-13 |
2008-09-25 |
Genentech Inc |
Treatment method
|
|
DOP2006000029A
(es)
*
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
|
KR101335798B1
(ko)
*
|
2005-02-15 |
2013-12-02 |
듀크 유니버시티 |
항-ｃｄ19 항체 및 종양학에서 이의 용도
|
|
US8444973B2
(en)
|
2005-02-15 |
2013-05-21 |
Duke University |
Anti-CD19 antibodies and uses in B cell disorders
|
|
US20060280738A1
(en)
*
|
2005-06-08 |
2006-12-14 |
Tedder Thomas F |
Anti-CD19 antibody therapy for transplantation
|
|
TW200714289A
(en)
*
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
|
ES2665422T3
(es)
|
2005-03-03 |
2018-04-25 |
Immunomedics Inc. |
Anticuerpos L243 humanizados
|
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
|
AR053579A1
(es)
*
|
2005-04-15 |
2007-05-09 |
Genentech Inc |
Tratamiento de la enfermedad inflamatoria intestinal (eii)
|
|
JP2008538767A
(ja)
*
|
2005-04-22 |
2008-11-06 |
ジェネンテック・インコーポレーテッド |
Ｃｄ２０抗体による認知症又はアルツハイマー病の治療方法
|
|
CA2606081C
(en)
|
2005-04-26 |
2013-09-17 |
Markus M. Heiss |
Combination of the application of antibodies for immunostimulation together with glucocorticoids
|
|
CA2607281C
(en)
*
|
2005-05-05 |
2023-10-03 |
Duke University |
Anti-cd19 antibody therapy for autoimmune disease
|
|
ATE460672T1
(de)
*
|
2005-05-20 |
2010-03-15 |
Genentech Inc |
Vorbehandlung einer biologischen probe aus einem individuum mit autoimmunkrankheit
|
|
JP2009502936A
(ja)
|
2005-07-25 |
2009-01-29 |
トルビオン ファーマシューティカルズ， インコーポレイテッド |
Ｃｄ２０特異的結合分子の単一投与量
|
|
HRP20140338T1
(hr)
|
2005-07-25 |
2014-06-20 |
Emergent Product Development Seattle, Llc |
Smanjenje broja b-stanica upotrebom molekula koje se specifiäśno vežu na cd37 i cd20
|
|
WO2007016562A2
(en)
*
|
2005-07-29 |
2007-02-08 |
Amgen Inc. |
Formulations that inhibit protein aggregation
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
WO2007062090A2
(en)
|
2005-11-23 |
2007-05-31 |
Genentech, Inc. |
Methods and compositions related to b cell assays
|
|
EP2650306A1
(en)
|
2006-03-06 |
2013-10-16 |
Aeres Biomedical Limited |
Humanized Anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CA2644906C
(en)
*
|
2006-03-06 |
2016-05-10 |
Medimmune, Inc. |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
WO2007146968A2
(en)
|
2006-06-12 |
2007-12-21 |
Trubion Pharmaceuticals, Inc. |
Single-chain multivalent binding proteins with effector function
|
|
PL2383297T3
(pl)
|
2006-08-14 |
2013-06-28 |
Xencor Inc |
Zoptymalizowane przeciwciała ukierunkowane na CD19
|
|
KR101456728B1
(ko)
*
|
2006-09-08 |
2014-10-31 |
메디뮨 엘엘씨 |
인간화 항-ｃｄ19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도
|
|
WO2008034076A2
(en)
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Cyclophosphamide in combination with immune therapeutics
|
|
WO2008034071A2
(en)
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Method of identifying patients suitable for high-dose cyclophosphamide treatment
|
|
WO2008034074A2
(en)
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Cyclosphosphamide in combination with anti-idiotypic vaccines
|
|
WO2008156494A1
(en)
*
|
2006-11-03 |
2008-12-24 |
The Johns Hopkins University |
Use of high-dose oxazaphosphorine drugs in combination with monoclonal antibodies for treating immune disorders
|
|
KR101552735B1
(ko)
|
2006-12-01 |
2015-09-14 |
메다렉스, 엘.엘.시. |
씨디22에 결합하는 인간 항체 및 이의 용도
|
|
WO2008098145A1
(en)
*
|
2007-02-07 |
2008-08-14 |
University Of Washington |
Methods for modulating antigen-specific b cell responses
|
|
WO2008141278A1
(en)
*
|
2007-05-11 |
2008-11-20 |
Centocor, Inc. |
Method for preparing antibody conjugates
|
|
KR20190140090A
(ko)
|
2007-07-09 |
2019-12-18 |
제넨테크, 인크. |
폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지
|
|
EP2200631A1
(en)
|
2007-10-16 |
2010-06-30 |
Zymogenetics, Inc. |
Combination of blys inhibition and anti-cd 20 agents for treatment of autoimmune disease
|
|
WO2009054556A1
(en)
*
|
2007-10-24 |
2009-04-30 |
Sang Yun Nam |
Method for preparation of therapeutic b cells against autoimmune diseases which are induced by autoimmune cytotoxicity
|
|
US9026372B2
(en)
|
2007-11-21 |
2015-05-05 |
Accentia Biopharmaceuticals, Inc. |
Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen
|
|
EP2077281A1
(en)
|
2008-01-02 |
2009-07-08 |
Bergen Teknologioverforing AS |
Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome
|
|
CN101959429B
(zh)
|
2008-01-08 |
2014-09-10 |
阿克塞利亚制药公司 |
抗微生物肽系统的激动剂
|
|
WO2009105548A2
(en)
*
|
2008-02-19 |
2009-08-27 |
Children's Medical Center Corporation |
Methods for treating diabetes
|
|
DK2257301T3
(da)
|
2008-03-03 |
2014-04-28 |
Univ Miami |
Immunterapi baseret på allogene cancerceller.
|
|
ES2610327T3
(es)
*
|
2008-03-13 |
2017-04-27 |
Biotest Ag |
Régimen de dosificación de anticuerpos anti-CD4 para el tratamiento de enfermedades autoinmunitarias
|
|
HUE028962T2
(en)
*
|
2008-03-13 |
2017-01-30 |
Biotest Ag |
Active ingredient for treating disease
|
|
BRPI0909048A2
(pt)
*
|
2008-03-13 |
2015-11-24 |
Biotest Ag |
composição farmacêutica, e, método de tratamento de uma doença autoimune
|
|
KR20110017356A
(ko)
|
2008-03-20 |
2011-02-21 |
유니버시티 오브 마이애미 |
열충격 단백질 ｇｐ96 백신접종 및 이를 사용하는 방법
|
|
EP2365003A1
(en)
|
2008-04-11 |
2011-09-14 |
Emergent Product Development Seattle, LLC |
CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
JP6049163B2
(ja)
*
|
2008-07-21 |
2016-12-21 |
イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． |
改善された治療上の特徴のための抗体の構造変異体
|
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
|
KR20110061630A
(ko)
*
|
2008-09-29 |
2011-06-09 |
바이오테스트 아게 |
질병 치료용 조성물
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
EP3912643B8
(en)
|
2009-02-13 |
2023-08-23 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
CN104059955A
(zh)
|
2009-08-11 |
2014-09-24 |
弗·哈夫曼-拉罗切有限公司 |
在无谷氨酰胺的细胞培养基中的蛋白质生产
|
|
US8728730B2
(en)
*
|
2009-09-03 |
2014-05-20 |
Genentech, Inc. |
Methods for treating, diagnosing, and monitoring rheumatoid arthritis
|
|
EP3009455A1
(en)
|
2009-09-16 |
2016-04-20 |
Immunomedics Inc. |
Class i anti-cea antibodies and uses thereof
|
|
US20110070227A1
(en)
*
|
2009-09-18 |
2011-03-24 |
Anna-Marie Novotney-Barry |
Treatment of Autoimmune and Inflammatory Diseases
|
|
GB0917054D0
(en)
*
|
2009-09-29 |
2009-11-11 |
Cytoguide As |
Agents, uses and methods
|
|
GB0920944D0
(en)
|
2009-11-30 |
2010-01-13 |
Biotest Ag |
Agents for treating disease
|
|
ES2978177T3
(es)
|
2009-12-02 |
2024-09-06 |
Immunomedics Inc |
Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer
|
|
AU2011203890B2
(en)
*
|
2010-01-11 |
2013-05-30 |
Center For Molecular Medicine And Immunology |
Enhanced cytotoxicity of anti-CD74 and anti-HLA-DR antibodies with interferon-gamma
|
|
TW201129384A
(en)
|
2010-02-10 |
2011-09-01 |
Immunogen Inc |
CD20 antibodies and uses thereof
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
RU2013120302A
(ru)
|
2010-10-01 |
2014-11-20 |
Модерна Терапьютикс, Инк. |
Сконструированные нуклеиновые кислоты и способы их применения
|
|
CN102586408B
(zh)
*
|
2011-01-12 |
2015-08-19 |
首都医科大学附属北京安贞医院 |
高血压易感基因Mfn2单核苷酸多态性位点rs3820189的检测方法及检测试剂盒
|
|
BR112013021725A2
(pt)
|
2011-02-28 |
2016-11-01 |
Genentech Inc |
marcadores biológicos e métodos para prever resposta aos antagonistas de células b
|
|
EP2691101A2
(en)
|
2011-03-31 |
2014-02-05 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
AU2012250924B2
(en)
|
2011-05-02 |
2017-05-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
CA2842195A1
(en)
|
2011-07-18 |
2013-01-24 |
Immunomedics, Inc. |
Fty720 increases cd74 expression and sensitizes cancer cells to anti-cd74 antibody-mediated cell death
|
|
HUE058855T2
(hu)
|
2011-08-16 |
2022-09-28 |
Morphosys Ag |
Kombinációs terápia, CD19 elleni ellenanyag és purinanalóg alkalmazásával
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
RU2648950C2
(ru)
|
2011-10-03 |
2018-04-02 |
Модерна Терапьютикс, Инк. |
Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение
|
|
CA2851280C
(en)
|
2011-10-11 |
2021-05-18 |
The Brigham And Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
CA2853637C
(en)
|
2011-10-26 |
2023-04-04 |
Novartis Ag |
Anti-canine cd20 monoclonal antibodies and methods of use
|
|
CA2853138A1
(en)
|
2011-12-05 |
2013-06-13 |
Immunomedics, Inc. |
Therapeutic use of anti-cd22 antibodies for inducing trogocytosis
|
|
US9757458B2
(en)
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
|
CN104114572A
(zh)
|
2011-12-16 |
2014-10-22 |
现代治疗公司 |
经修饰的核苷、核苷酸和核酸组合物
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
AU2013243948A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins associated with human disease
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
KR101482237B1
(ko)
*
|
2012-05-11 |
2015-01-14 |
가톨릭대학교 산학협력단 |
항 ｉｌ-６ｒ 및 ｔｎｆｒ２을 포함하는 이중특이적 단백질을 발현하는 미니서클 벡터를 포함하는 자가 면역 질환 치료용 약학 조성물
|
|
KR102165464B1
(ko)
|
2012-07-19 |
2020-10-14 |
레드우드 바이오사이언스 인코포레이티드 |
Cd22에 대해 특이적인 항체 및 이들의 사용 방법
|
|
AU2013302696B9
(en)
|
2012-08-14 |
2018-08-09 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
WO2014081507A1
(en)
|
2012-11-26 |
2014-05-30 |
Moderna Therapeutics, Inc. |
Terminally modified rna
|
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
WO2015012904A2
(en)
|
2012-12-13 |
2015-01-29 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
SI2900277T1
(sl)
|
2012-12-13 |
2022-05-31 |
Immunomedics, Inc. |
Odmerki imunokonjugatov protiteles in SN-38 za boljšo učinkovitost in zmanjšano toksičnost
|
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US12310958B2
(en)
|
2012-12-13 |
2025-05-27 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US20240139324A1
(en)
|
2012-12-13 |
2024-05-02 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
|
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
|
CA2895284A1
(en)
|
2013-02-07 |
2014-08-14 |
Immunomedics, Inc. |
Pro-drug form (p2pdox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer
|
|
EP2774930A1
(en)
|
2013-03-07 |
2014-09-10 |
Aptenia S.R.L. |
Metallocene compounds and labeled molecules comprising the same for in vivo imaging.
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
JP2016538829A
(ja)
|
2013-10-03 |
2016-12-15 |
モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
低密度リポタンパク質受容体をコードするポリヌクレオチド
|
|
WO2015126548A1
(en)
|
2014-02-21 |
2015-08-27 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to trop-2 expressing cells
|
|
US9139649B2
(en)
|
2014-02-25 |
2015-09-22 |
Immunomedics, Inc. |
Humanized anti-CD22 antibody
|
|
IL292311A
(en)
|
2014-04-03 |
2022-06-01 |
Igm Biosciences Inc |
J-chain qualified
|
|
WO2015200260A1
(en)
|
2014-06-24 |
2015-12-30 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
|
GB201412658D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
|
EP2990416B1
(en)
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
|
WO2016037985A1
(en)
|
2014-09-08 |
2016-03-17 |
Ruprecht-Karls-Universität Heidelberg |
Construct for the delivery of a molecule into the cytoplasm of a cell
|
|
CN117138060A
(zh)
|
2014-10-07 |
2023-12-01 |
免疫医疗公司 |
抗体-药物缀合物的新辅助剂用途
|
|
KR102357312B1
(ko)
|
2015-03-04 |
2022-02-03 |
아이쥐엠 바이오사이언스 인코포레이티드 |
Ｃｄ20 결합 분자 및 그의 용도
|
|
WO2016172427A1
(en)
|
2015-04-22 |
2016-10-27 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
|
AU2016271124C1
(en)
|
2015-05-30 |
2020-05-14 |
Molecular Templates, Inc. |
De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
|
MX391086B
(es)
|
2015-06-24 |
2025-03-21 |
Hoffmann La Roche |
Anticuerpos anti-receptor de transferrina con afinidad diseñada.
|
|
EP4257134A3
(en)
|
2015-06-25 |
2024-01-24 |
Immunomedics, Inc. |
Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
PL3316885T3
(pl)
|
2015-07-01 |
2021-12-06 |
Immunomedics, Inc. |
Immunokoniugaty przeciwciało-sn-38 z linkerem cl2a
|
|
GB201601073D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies
|
|
GB201601075D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies molecules
|
|
GB201601077D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibody molecule
|
|
EP3352760B1
(en)
|
2015-09-21 |
2026-03-11 |
Aptevo Research and Development LLC |
Cd3 binding polypeptides
|
|
EP3824903A1
(en)
|
2015-09-30 |
2021-05-26 |
IGM Biosciences Inc. |
Binding molecules with modified j-chain
|
|
EP3356401B1
(en)
|
2015-09-30 |
2020-06-24 |
IGM Biosciences, Inc. |
Binding molecules with modified j-chain
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
NZ741067A
(en)
|
2015-10-02 |
2023-07-28 |
Hoffmann La Roche |
Bispecific anti-human cd20/human transferrin receptor antibodies and methods of use
|
|
KR102783230B1
(ko)
|
2015-11-09 |
2025-03-19 |
알.피.쉐러 테크놀러지즈 엘엘씨 |
항-cd22 항체-메이탄신 콘쥬게이트 및 그것의 사용 방법
|
|
CN108367071B
(zh)
|
2015-11-13 |
2022-05-13 |
达纳-法伯癌症研究所有限公司 |
用于癌症免疫疗法的nkg2d-ig融合蛋白
|
|
CN115969970A
(zh)
|
2016-02-10 |
2023-04-18 |
免疫医疗公司 |
Abcg2抑制剂与sacituzumab govitecan的组合
|
|
JP7379795B2
(ja)
|
2016-04-27 |
2023-11-15 |
イミューノメディクス、インコーポレイテッド |
チェックポイント阻害薬に再発／耐性を示す腫瘍を治療するための抗Ｔｒｏｐ－２－ＳＮ－３８抗体薬物複合体の効果
|
|
GB2552774A
(en)
*
|
2016-07-12 |
2018-02-14 |
Evox Therapeutics Ltd |
EV-Mediated delivery of binding protein-small molecule conjugates
|
|
US10918734B2
(en)
|
2017-03-27 |
2021-02-16 |
Immunomedics, Inc. |
Treatment of high Trop-2 expressing triple negative breast cancer (TNBC) with sacituzumab govitecan (IMMU-132) overcomes homologous recombination repair (HRR) rescue mediated by Rad51
|
|
WO2018187074A1
(en)
|
2017-04-03 |
2018-10-11 |
Immunomedics, Inc. |
Subcutaneous administration of antibody-drug conjugates for cancer therapy
|
|
CN108359004A
(zh)
*
|
2018-01-12 |
2018-08-03 |
中国农业科学院北京畜牧兽医研究所 |
犬重组干扰素-λ1及其制备方法与应用
|
|
EP4178624A2
(en)
|
2020-07-07 |
2023-05-17 |
Bionecure Therapeutics, Inc. |
Maytansinoids as adc payloads and their use for the treatment of cancer
|
|
EP4178530A1
(en)
|
2020-07-09 |
2023-05-17 |
F. Hoffmann-La Roche AG |
Concentrated compositions of proteins, their preparation and use thereof
|
|
US20250073349A1
(en)
|
2021-05-10 |
2025-03-06 |
Kawasaki Institute Of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|
|
CN113855792B
(zh)
*
|
2021-12-01 |
2022-03-01 |
上海惠盾因泰生物科技有限公司 |
重组hEGF-CRM197肿瘤治疗性疫苗配制剂
|
|
CN114778417B
(zh)
*
|
2022-04-29 |
2024-02-13 |
上海顿慧医疗科技发展有限公司 |
免疫检查点抑制剂相关不良反应风险预测的模型建立方法
|
|
IL318865A
(en)
|
2022-08-10 |
2025-04-01 |
Kowa Co |
New drug complex
|
|
CN115998903A
(zh)
*
|
2022-12-27 |
2023-04-25 |
浙江大学杭州国际科创中心 |
聚合物纳米颗粒在制备用于蛋白质降解的药物中的应用
|