JP2003335776A5 - - Google Patents

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Publication number
JP2003335776A5
JP2003335776A5 JP2002229532A JP2002229532A JP2003335776A5 JP 2003335776 A5 JP2003335776 A5 JP 2003335776A5 JP 2002229532 A JP2002229532 A JP 2002229532A JP 2002229532 A JP2002229532 A JP 2002229532A JP 2003335776 A5 JP2003335776 A5 JP 2003335776A5
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JP
Japan
Prior art keywords
phenyl
benzoazosin
butoxyethoxy
sulfinyl
imidazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002229532A
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English (en)
Japanese (ja)
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JP4316203B2 (ja
JP2003335776A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2003335776A publication Critical patent/JP2003335776A/ja
Publication of JP2003335776A5 publication Critical patent/JP2003335776A5/ja
Application granted granted Critical
Publication of JP4316203B2 publication Critical patent/JP4316203B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2002229532A 2001-08-08 2002-08-07 二環性化合物、その製造法および用途 Expired - Lifetime JP4316203B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001240750 2001-08-08
JP2001-240750 2001-08-08
JP2002-66809 2002-03-12
JP2002066809 2002-03-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006355701A Division JP4358851B2 (ja) 2001-08-08 2006-12-28 二環性化合物、その製造法および用途

Publications (3)

Publication Number Publication Date
JP2003335776A JP2003335776A (ja) 2003-11-28
JP2003335776A5 true JP2003335776A5 (https=) 2007-12-13
JP4316203B2 JP4316203B2 (ja) 2009-08-19

Family

ID=26620186

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2002229532A Expired - Lifetime JP4316203B2 (ja) 2001-08-08 2002-08-07 二環性化合物、その製造法および用途
JP2006355701A Expired - Lifetime JP4358851B2 (ja) 2001-08-08 2006-12-28 二環性化合物、その製造法および用途
JP2009147839A Expired - Lifetime JP5275148B2 (ja) 2001-08-08 2009-06-22 二環性化合物、その製造法および用途
JP2013050937A Pending JP2013136629A (ja) 2001-08-08 2013-03-13 二環性化合物、その製造法および用途

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2006355701A Expired - Lifetime JP4358851B2 (ja) 2001-08-08 2006-12-28 二環性化合物、その製造法および用途
JP2009147839A Expired - Lifetime JP5275148B2 (ja) 2001-08-08 2009-06-22 二環性化合物、その製造法および用途
JP2013050937A Pending JP2013136629A (ja) 2001-08-08 2013-03-13 二環性化合物、その製造法および用途

Country Status (13)

Country Link
US (7) US7371772B2 (https=)
EP (3) EP2206702B1 (https=)
JP (4) JP4316203B2 (https=)
AR (1) AR034985A1 (https=)
AT (2) ATE539062T1 (https=)
AU (1) AU2002328092A1 (https=)
CA (2) CA2607992A1 (https=)
DE (1) DE60235632D1 (https=)
DK (2) DK2206702T3 (https=)
ES (2) ES2339340T3 (https=)
PE (1) PE20030329A1 (https=)
PT (2) PT1423376E (https=)
WO (1) WO2003014105A1 (https=)

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WO2008109591A1 (en) * 2007-03-08 2008-09-12 Lexicon Pharmaceuticals, Inc. Phlorizin analogs as inhibitors of sodium glucose co-transporter 2
RU2011119533A (ru) * 2008-10-17 2012-11-27 Инваск Терапеутикс, Инк. Композиции и способы для лечения нарушений деятельности, связанных с ренин-ангиотензин-альдостероновой системой (раас)
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EP2552429A1 (en) 2010-04-02 2013-02-06 Phivco-1 LLC Combination therapy comprising a ccr5 antagonist, a hiv-1 protease inhibitor and a pharmacokinetic enhancer
WO2012047630A2 (en) * 2010-09-27 2012-04-12 Martin Teintze N-alkyl or n-aryl substituted guanide and biguanide compounds and methods of their use
EP2741777B1 (en) 2011-08-12 2017-01-18 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical compositions for treatment of pulmonary hypertension
HK1232147A1 (zh) 2014-03-21 2018-01-05 Tobira Therapeutics, Inc. 用於治疗纤维化的赛尼克韦罗
US20170105969A1 (en) * 2014-06-02 2017-04-20 Tobira Therapeutics, Inc. Cenicriviroc for the treatment of hiv-2 infection
BR112017004708A2 (pt) 2014-09-12 2017-12-05 Tobira Therapeutics Inc terapia de combinação de cenicriviroc para o tratamento de fibrose
JP6716568B2 (ja) * 2014-12-23 2020-07-01 トビラ セラピューティクス， インコーポレイテッド セニクリビロックの製造方法及び関連類似体
BR112017016388A2 (pt) 2015-02-10 2018-03-27 Tobira Therapeutics, Inc. cenicriviroc para o tratamento da fibrose
KR101938036B1 (ko) * 2015-04-16 2019-01-14 서울대학교산학협력단 고혈압 치료제를 이용한 흡연 및 비흡연자의 폐암 억제 방법
JP2019520427A (ja) * 2016-06-21 2019-07-18 トビラ セラピューティクス， インコーポレイテッド 精製されたセニクリビロク及びセニクリビロク製造のための精製された中間体
MX2019002057A (es) * 2016-08-31 2019-11-18 Tobira Therapeutics Inc Formas solidas de mesilato de cenicriviroc y procesos para elaborar formas sólidas de mesilato de cenicriviroc.
ES2906992T3 (es) 2016-12-09 2022-04-21 Medshine Discovery Inc Compuesto de bifenilo como antagonista del receptor CCR2/CCR5
CA3051977A1 (en) 2017-02-24 2018-08-30 Genfit Pharmaceutical compositions for combination therapy
WO2019149089A1 (zh) 2018-02-02 2019-08-08 四川科伦博泰生物医药股份有限公司 含有羧酸基团的苯并氮杂环类化合物及其制备方法和用途
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WO2019238041A1 (zh) * 2018-06-12 2019-12-19 南京明德新药研发有限公司 一种丙烯酰胺类化合物的晶型及其制备方法
WO2020207263A1 (zh) * 2019-04-08 2020-10-15 四川科伦博泰生物医药股份有限公司 苯并咪唑化合物、其制备方法及其用途
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WO2023143112A1 (zh) * 2022-01-26 2023-08-03 无锡瓴方生物医药科技有限公司 氮杂苯并八元环化合物的盐型、晶型及其应用
WO2024240025A1 (zh) * 2023-05-22 2024-11-28 无锡瓴方生物医药科技有限公司 一种联合用药物组合物及其应用

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JP2004123694A (ja) 2002-03-12 2004-04-22 Takeda Chem Ind Ltd 光学活性スルホキシド誘導体の製造法
WO2005089714A1 (ja) * 2004-03-24 2005-09-29 Takeda Pharmaceutical Company Limited エマルション安定化製剤
CA2560298A1 (en) * 2004-03-24 2005-09-29 Takeda Pharmaceutical Company Limited Preparation with elevated content
WO2006059716A1 (ja) * 2004-12-03 2006-06-08 Takeda Pharmaceutical Company Limited 固形製剤
US20080108586A1 (en) 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
EP2552429A1 (en) 2010-04-02 2013-02-06 Phivco-1 LLC Combination therapy comprising a ccr5 antagonist, a hiv-1 protease inhibitor and a pharmacokinetic enhancer
CN103402998B (zh) 2010-11-18 2017-09-26 耶鲁大学 具有募集抗体并对人体免疫缺陷病毒进入有抑制活性的双功能分子
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HK1232147A1 (zh) 2014-03-21 2018-01-05 Tobira Therapeutics, Inc. 用於治疗纤维化的赛尼克韦罗
JP6716568B2 (ja) 2014-12-23 2020-07-01 トビラ セラピューティクス， インコーポレイテッド セニクリビロックの製造方法及び関連類似体
BR112017016388A2 (pt) 2015-02-10 2018-03-27 Tobira Therapeutics, Inc. cenicriviroc para o tratamento da fibrose

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