JP2007523200A5 - - Google Patents
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- Publication number
- JP2007523200A5 JP2007523200A5 JP2006554355A JP2006554355A JP2007523200A5 JP 2007523200 A5 JP2007523200 A5 JP 2007523200A5 JP 2006554355 A JP2006554355 A JP 2006554355A JP 2006554355 A JP2006554355 A JP 2006554355A JP 2007523200 A5 JP2007523200 A5 JP 2007523200A5
- Authority
- JP
- Japan
- Prior art keywords
- substances
- densities
- weights
- vol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63862804P | 2004-12-22 | 2004-12-22 | |
| US63881504P | 2004-12-23 | 2004-12-23 | |
| PCT/US2005/046856 WO2006069333A1 (en) | 2004-12-22 | 2005-12-22 | Method of purifying macrolides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007523200A JP2007523200A (ja) | 2007-08-16 |
| JP2007523200A5 true JP2007523200A5 (https=) | 2008-12-25 |
Family
ID=36128612
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006554356A Pending JP2007523201A (ja) | 2004-12-22 | 2005-12-22 | タクロリムスを精製する方法 |
| JP2006554355A Pending JP2007523200A (ja) | 2004-12-22 | 2005-12-22 | マクロライドを精製する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006554356A Pending JP2007523201A (ja) | 2004-12-22 | 2005-12-22 | タクロリムスを精製する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20060142565A1 (https=) |
| EP (2) | EP1828204A1 (https=) |
| JP (2) | JP2007523201A (https=) |
| CA (2) | CA2586700A1 (https=) |
| IL (2) | IL183241A0 (https=) |
| MX (2) | MX2007005867A (https=) |
| TW (2) | TW200637834A (https=) |
| WO (2) | WO2006069333A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008059516A2 (en) * | 2006-08-21 | 2008-05-22 | Concord Biotech Limited | Process for purification of macrolides |
| WO2008065887A1 (en) * | 2006-11-27 | 2008-06-05 | Terumo Kabushiki Kaisha | Process for producing o-alkylated rapamycin derivative, and o-alkylated rapamycin derivative |
| KR101003042B1 (ko) * | 2008-03-17 | 2010-12-21 | 종근당바이오 주식회사 | 고순도 타크로리무스의 정제 방법 |
| GB201020032D0 (en) * | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| KR101344012B1 (ko) | 2012-04-09 | 2013-12-23 | 인하대학교 산학협력단 | 모사이동층 크로마토그래피를 이용하여 타크로리무스와 아스코마이신의 혼합액으로부터 타크로리무스를 분리하는 방법 |
| CN103554133B (zh) * | 2013-10-31 | 2015-06-24 | 国药集团川抗制药有限公司 | 一种制备高纯度他克莫司的工艺 |
| CN105301159B (zh) * | 2015-10-29 | 2017-01-18 | 无锡福祈制药有限公司 | 一种西罗莫司的高效液相色谱分析方法 |
| CN117402175A (zh) * | 2023-10-18 | 2024-01-16 | 国药集团川抗制药有限公司 | 一种他克莫司的结晶方法及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3244592A (en) * | 1962-06-09 | 1966-04-05 | Arai Tadashi | Ascomycin and process for its production |
| US3993749A (en) * | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
| US4160861A (en) * | 1977-10-03 | 1979-07-10 | Merck & Co., Inc. | Method for the separation of antibiotic macrolides |
| US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
| US5182207A (en) * | 1984-09-14 | 1993-01-26 | American Cyanamid Company | Strains of streptomyces thermoarchaensis |
| US4874843A (en) * | 1987-12-03 | 1989-10-17 | Eli Lilly And Company | Chromatographic purification process |
| JP2639737B2 (ja) * | 1990-01-23 | 1997-08-13 | 寳酒造株式会社 | 新規ｒ１０６類化合物 |
| US5116756A (en) * | 1991-01-28 | 1992-05-26 | Merck & Co., Inc. | Process for producing FK-506 |
| US5194378A (en) * | 1991-01-28 | 1993-03-16 | Merck & Co., Inc. | Process for producing fk-506 |
| US5091389A (en) * | 1991-04-23 | 1992-02-25 | Merck & Co., Inc. | Lipophilic macrolide useful as an immunosuppressant |
| US5227295A (en) * | 1991-11-08 | 1993-07-13 | Dowelanco | Process for isolating A83543 and its components |
| WO1993018042A1 (en) * | 1992-03-02 | 1993-09-16 | Pfizer Inc. | Desosamino derivatives of macrolides as immunosuppressants and antifungal agents |
| US5612316A (en) * | 1992-03-02 | 1997-03-18 | Pfizer Inc. | Fluorosugar derivatives of macrolides |
| US5264355A (en) * | 1992-07-02 | 1993-11-23 | Merck & Co., Inc. | Methlating enzyme from streptomyces MA6858 |
| UA41884C2 (uk) * | 1993-11-05 | 2001-10-15 | Амерікан Хоум Продактс Корпорейшн | Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів |
| US5622866A (en) * | 1994-06-23 | 1997-04-22 | Merck & Co., Inc. | Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces |
| GB9618952D0 (en) * | 1996-09-11 | 1996-10-23 | Sandoz Ltd | Process |
| US5616595A (en) * | 1995-06-07 | 1997-04-01 | Abbott Laboratories | Process for recovering water insoluble compounds from a fermentation broth |
| NZ510819A (en) * | 1998-10-02 | 2004-03-26 | Kosan Biosciences Inc | Polyketide synthase enzymes and recombinant DNA constructs therefor |
| AU1214400A (en) * | 1998-10-20 | 2000-05-08 | Ben Venue Laboratories, Inc. | Process for purification of solvents useful in the preparation of pharmaceuticalcompositions |
| CA2351222A1 (en) * | 1998-11-09 | 2000-05-18 | Aventis Pharma Deutschland Gmbh | Vancoresmycin, a process for its production and its use as a pharmaceutical |
| CN1154651C (zh) * | 1999-05-25 | 2004-06-23 | 藤泽药品工业株式会社 | 分离类似的有机化合物的方法 |
| TW553946B (en) * | 1999-09-08 | 2003-09-21 | Fujisawa Pharmaceutical Co | Method for separating lactone-containing high-molecular weight compounds |
| HRP20020683A2 (en) * | 2000-02-24 | 2004-12-31 | Biogal Gyogyszergyar | Method of purifying a fermentation broth |
| MXPA04007847A (es) * | 2002-02-13 | 2005-02-24 | Biogal Gyogyszergyar | Metodo para extraer un macrolido de biomateria. |
| TW200523266A (en) * | 2003-07-24 | 2005-07-16 | Biogal Gyogyszergyar | Method of purifying macrolides |
-
2005
- 2005-12-22 WO PCT/US2005/046856 patent/WO2006069333A1/en not_active Ceased
- 2005-12-22 TW TW094145958A patent/TW200637834A/zh unknown
- 2005-12-22 EP EP05855421A patent/EP1828204A1/en not_active Withdrawn
- 2005-12-22 CA CA002586700A patent/CA2586700A1/en not_active Abandoned
- 2005-12-22 JP JP2006554356A patent/JP2007523201A/ja active Pending
- 2005-12-22 EP EP05855772A patent/EP1828205A1/en not_active Withdrawn
- 2005-12-22 TW TW094145959A patent/TW200637835A/zh unknown
- 2005-12-22 US US11/317,155 patent/US20060142565A1/en not_active Abandoned
- 2005-12-22 WO PCT/US2005/047264 patent/WO2006069386A1/en not_active Ceased
- 2005-12-22 CA CA002586692A patent/CA2586692A1/en not_active Abandoned
- 2005-12-22 JP JP2006554355A patent/JP2007523200A/ja active Pending
- 2005-12-22 US US11/317,152 patent/US20060149057A1/en not_active Abandoned
- 2005-12-22 MX MX2007005867A patent/MX2007005867A/es unknown
- 2005-12-22 MX MX2007005868A patent/MX2007005868A/es not_active Application Discontinuation
-
2007
- 2007-05-15 IL IL183241A patent/IL183241A0/en unknown
- 2007-05-15 IL IL183240A patent/IL183240A0/en unknown
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