JP2002538775A - 骨刺激因子 - Google Patents

骨刺激因子

Info

Publication number
JP2002538775A
JP2002538775A JP2000593635A JP2000593635A JP2002538775A JP 2002538775 A JP2002538775 A JP 2002538775A JP 2000593635 A JP2000593635 A JP 2000593635A JP 2000593635 A JP2000593635 A JP 2000593635A JP 2002538775 A JP2002538775 A JP 2002538775A
Authority
JP
Japan
Prior art keywords
polypeptide
seq
amino acid
acid sequence
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000593635A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002538775A5 (enExample
Inventor
チャーク シン タム
Original Assignee
オステオファーム インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オステオファーム インコーポレイテッド filed Critical オステオファーム インコーポレイテッド
Publication of JP2002538775A publication Critical patent/JP2002538775A/ja
Publication of JP2002538775A5 publication Critical patent/JP2002538775A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000593635A 1999-01-13 2000-01-13 骨刺激因子 Pending JP2002538775A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/229,304 US6693081B2 (en) 1995-09-26 1999-01-13 Bone stimulating factor
US09/229,304 1999-01-13
PCT/CA2000/000031 WO2000042069A1 (en) 1999-01-13 2000-01-13 Bone stimulating factor

Publications (2)

Publication Number Publication Date
JP2002538775A true JP2002538775A (ja) 2002-11-19
JP2002538775A5 JP2002538775A5 (enExample) 2007-03-01

Family

ID=22860649

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000593635A Pending JP2002538775A (ja) 1999-01-13 2000-01-13 骨刺激因子

Country Status (19)

Country Link
US (2) US6693081B2 (enExample)
EP (1) EP1161450A1 (enExample)
JP (1) JP2002538775A (enExample)
KR (1) KR20010101425A (enExample)
CN (1) CN1341120A (enExample)
AU (1) AU779261B2 (enExample)
BG (1) BG105682A (enExample)
BR (1) BR0007816A (enExample)
CA (1) CA2358908A1 (enExample)
CZ (1) CZ20012456A3 (enExample)
HU (1) HUP0105004A2 (enExample)
IL (1) IL143990A0 (enExample)
IS (1) IS5999A (enExample)
MA (1) MA25594A1 (enExample)
MX (1) MXPA01007043A (enExample)
NO (1) NO20013257L (enExample)
NZ (1) NZ512637A (enExample)
PL (1) PL349786A1 (enExample)
WO (1) WO2000042069A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
AU5379200A (en) * 1999-06-02 2000-12-28 Osteopharm Inc. Bone stimulating factor
WO2004015378A1 (en) * 2002-07-05 2004-02-19 Gaspardo Seminatrici S.P.A. A volumetric metering device for the metered delivery of granular and powdery materials, particularly for machines for distributing the said materials
AU2003272814A1 (en) 2003-10-02 2005-05-19 Ibrahim Al-Habdan Peptide for promoting healing of fractures
EP2718728A1 (en) * 2011-06-10 2014-04-16 Université Libre de Bruxelles Targets and agents for the treatment of impaired bone fracture healing
CN103159762B (zh) * 2013-03-25 2015-04-15 华东理工大学 表吲哚二酮衍生物及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08508158A (ja) * 1993-03-12 1996-09-03 オステオファーム リミテッド 骨刺激因子
WO1997012036A2 (en) * 1995-09-26 1997-04-03 Gensci Regeneration Sciences Inc. Bone stimulating factor
JPH09512253A (ja) * 1994-04-18 1997-12-09 オステオファーム リミテッド ヒトの骨刺激因子

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320118A (en) 1980-12-22 1982-03-16 Syntex (U.S.A.) Inc. Deca-, undeca-, dodeca- and tridecapeptides with thymic activity
US4897348A (en) 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US5354557A (en) 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5264214A (en) 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
JP3051160B2 (ja) * 1988-12-08 2000-06-12 ノバルティス・アクチエンゲゼルシャフト 好中球活性化ペプチド‐２
US5461034A (en) 1989-02-23 1995-10-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
EP0513201A1 (en) 1990-02-01 1992-11-19 University Of South Florida Leukocyte-derived growth factor
CA2040264A1 (en) 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
AU668347B2 (en) 1990-11-21 1996-05-02 Torrey Pines Institute For Molecular Studies Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
CA2098921C (en) * 1990-12-21 2000-12-05 Russel B. Whitman Angiogenic peptides
US5208219A (en) 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
EP0499242B1 (en) 1991-02-15 1996-06-26 Takeda Chemical Industries, Ltd. Stimulation of endosteal bone formation with a cell growth factor
EP0504938A3 (en) 1991-03-22 1993-04-14 Suntory Limited Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
US5792664A (en) 1992-05-29 1998-08-11 The Rockefeller University Methods for producing and analyzing biopolymer ladders
DE69332377T2 (de) * 1992-07-13 2003-07-03 Bionebraska, Inc. Verfahren zur modifizierung rekombinanter polypeptide
US5304542A (en) 1992-08-28 1994-04-19 University Of Louisville Research Foundation, Inc. Use of platelet factor 4 to inhibit osteoblast proliferation
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
US5661127A (en) 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US5880094A (en) 1995-06-07 1999-03-09 Osteopharm Limited Polypeptides that stimulate bone growth
US6117839A (en) 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08508158A (ja) * 1993-03-12 1996-09-03 オステオファーム リミテッド 骨刺激因子
JPH09512253A (ja) * 1994-04-18 1997-12-09 オステオファーム リミテッド ヒトの骨刺激因子
WO1997012036A2 (en) * 1995-09-26 1997-04-03 Gensci Regeneration Sciences Inc. Bone stimulating factor

Also Published As

Publication number Publication date
US20020090671A1 (en) 2002-07-11
KR20010101425A (ko) 2001-11-14
CN1341120A (zh) 2002-03-20
CZ20012456A3 (cs) 2002-02-13
BG105682A (en) 2003-04-30
MA25594A1 (fr) 2002-12-31
NO20013257D0 (no) 2001-06-29
WO2000042069A1 (en) 2000-07-20
IS5999A (is) 2001-07-11
AU3028200A (en) 2000-08-01
MXPA01007043A (es) 2002-03-27
US6693081B2 (en) 2004-02-17
EP1161450A1 (en) 2001-12-12
BR0007816A (pt) 2002-12-31
US20040147450A1 (en) 2004-07-29
NZ512637A (en) 2003-08-29
PL349786A1 (en) 2002-09-09
NO20013257L (no) 2001-08-17
CA2358908A1 (en) 2000-07-20
AU779261B2 (en) 2005-01-13
IL143990A0 (en) 2002-04-21
HUP0105004A2 (hu) 2002-04-29

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